@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA1822: (2016-02-01 )
MVTGATSLSLVRDELFATMEQAEQGLEQFIAERQNGSLLQHAVECLQQIRGTLNLIELAGAELLAQEALQLATDIPTGVSEERDGQLAALGNALYVLRRYLENVEANRQEIPELLLPAINEVRCAAGQPALPESFFFSARLDIPRPPSTAIDHLPSEAELGEESRRMRHMYQIGLLGLIREQNLYPSLKLMGRALARLDSLHGGVARSRLCWIGAAAIESIVDGQLLPRKSRKQLFSRIDRELKQLLIGPAYEAPRHLLKELLYLVALSDGQGPRSREVRELHGLAPLPFTDHLLEEESQRLSGPGQSVMRSLSTAIREELAGVKDMLDLIERGVAQPDSLTNLHAQLGKLSKTLGMVGLNSAGTALQTQLPTVAAWAASGVADSPPALLRLADAVLYVESMVGNLERGERRIIRPTPAEPGQEADAFAVHQLAEARIVVIEEAKAGLALAKRAITAYLESNGDKLNLANVPASLQAVRGGLWFLGQERAALLVGGCADYIQQRMIETAQMPSEQMLETLADALTSLEYYLEGGAVLRPQGQPDVLDLASASVKALGLPVAA
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10......-..20.....-...-------30...-----.--...-----------.40........50--..------.......60........70........80.-------------.......90........100.------....---..110..--.....120.......130..-----....---.140----.......150...----....160....----...170-----........180---...--....190.......200.......-210..--.....--220.--------.------.....230..-----.....240...-------.--...250.......260------........------270.......280.......290....-------------...300.......--310------..--......320........-330......-----------.340.......----350.......360....------.....370.....---..380.......390.....-----..----------400.......410........420.......430-.-----......440-....----...450.......460.-------.....----.470.......480.....--..490...-....500..------.....510----------........520---------------......----...530...---------....----------540.--......550.......560-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTGA
T
S
L
S
L
V
R
D
E
L
F
A
-
T
M
E
Q
A
E
Q
G
L
-
E
Q
F
-------
I
A
ERQ-----N--
G
S
L
-----------
L
Q
H
A
V
E
C
L
Q
Q
I
R
---
G
T
------
L
N
L
I
E
LA
G
A
E
L
L
A
Q
E
A
L
Q
L
A
TDIPTGVSEE-------------RDG
Q
L
A
A
L
G
N
A
L
Y
V
L
R
R
Y
L
E
N
------VEA
N
---
R
Q
E
I
P
E
L
--
L
L
P
A
I
N
E
V
RCAAGQPALPES-----
F
F
F
S
---
A
RLD----IPRPP
S
T
A
I
DHLP----
S
E
A
E
L
G
E
E
S
R
R
----
M
R
H
M
Y
------
Q
I
G
L
L
G
L
I
R
EQ---NL
Y
--
P
S
L
K
L
M
G
R
A
L
A
R
L
D
S
L
H
G
G
V
A
R
S
R
-
L
C
W
I
G
--
A
A
A
I
E
--
S
I
VD--------G------QLL
P
R
K
S
R
K
Q
-----
L
F
S
R
I
D
R
E
L
K
Q
-------
L
--LIGPA
Y
E
A
P
R
H
L
L
K
E
-------
L
L
Y
L
V
A
LS------DGQGPRS
R
E
V
R
E
L
HGLAPLP
F
T
D
H
L
L
E
-------------
E
E
S
Q
RLSGP
G
Q
S
V
--
M
R
-------
S
L
--
S
T
A
I
R
E
E
-
L
A
G
V
K
D
M
L
D
-
L
I
E
R
GVAQP-----------
D
S
L
T
N
L
H
A
Q
L
G
----
K
L
S
K
T
L
GMVGL--NSAG------T
A
L
Q
TQL
P
T
V
A
A
W
---AASGVADS
P
P
A
L
L
R
L
A
D
A
V
L
-----
Y
V
----------
E
S
M
VG
N
L
E
RGE-
R
R
IIRPTPAEPGQE
A
D
A
F
A
V
H
Q
-L-----AE
A
R
I
V
V
I
E-EAKA----
G
L
A
L
A
K
R
A
I
T
A
Y
L
ESNG-------
D
K
L
N
L----ANVP
A
S
L
Q
A
V
RGG
L
W
F
LGQ--E
R
A
A
L
L
VG-
G
C
A
D
Y
I
Q
Q
R
------
M
I
E
T
AQM-----------
P
S
E
Q
M
L
E
T
L
-----------------
A
D
A
L
T
S
----
L
E
Y
Y
LEG
G
A
---------
V
LRP----------QGQP--
D
V
L
D
L
A
SA
S
V
K
ALGLPVAA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
68.96
14%
-44
- C3 -
3J5P
-
TRPV1_RAT
A:
[1-564]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
D
R
R
S
I
F
D
A
V
A
Q
S
N
C
Q
-
E
L
E
S
L
L
P
F
L
-
Q
R
S
-------
K
K
R
L
T
-----
D
--
S
E
F
-----------
K
D
P
E
T
G
K
T
C
L
L
K
---
A
M
------
L
N
L
H
N
--
G
Q
N
D
T
I
A
L
L
L
D
V
A
R
K
----------------------
T
D
S
L
K
Q
F
V
N
A
S
Y
T
D
S
Y
Y
K
G
Q
T
A
L
H
I
A
I
E
R
R
---
N
M
T
L
V
T
L
--
L
V
E
N
G
A
D
V
Q
A
A
A
N
G
D
F
F
K
K
T
KGRP
G
F
Y
F
G
EL
P
L
S
L
A
----
A
C
T
N
Q
L
A
I
V
K
F
L
L
Q
NSW
Q
P
A
D
I
S
A
R
D
S
V
GNT
V
L
H
A
L
V
------
E
V
A
D
N
T
V
D
N
T
K
F
V
T
S
M
Y
--
N
E
I
L
I
L
G
A
K
L
H
P
T
L
K
L
E
E
I
T
N
R
K
G
-
L
T
P
L
A
--
L
A
A
S
S
GK
I
G
V
L
--------
A
------
Y
I
L
Q
R
E
I
H
E
P
-----
E
C
R
H
L
S
R
K
F
T
E
-------
W
--
A
Y
G
P
V
H
S
S
L
Y
D
L
S
C
I
DTCEKNS
V
L
E
V
I
A
Y
S
------
S
S
E
T
P
N
R
------
H
D
M
L
L
V
E
P
L
N
R
L
L
Q
-------------
D
K
W
D
R
F
------------------
V
K
--
R
I
F
Y
F
N
F
-
F
V
Y
C
L
Y
M
I
I
-
F
T
A
A
A
Y
Y
R
P
VEGLPPYKLKN
T
V
G
D
Y
F
R
V
T
G
E
----
I
L
S
V
S
G
G
V
Y
F
F
--
F
R
G
I
------
Q
Y
F
L
Q
R
R
P
S
V
D
S
Y
---
S
E
I
L
F
F
V
Q
S
L
F
M
L
V
S
V
V
L
Y
F
S
QRKE
Y
V
----------
A
S
M
V
F
S
L
A
M
G
W
-
T
N
M
L
Y
Y
T
R
G
F
Q
Q
M
G
I
Y
A
V
M
I
E
K
-
M
-----
I
L
R
D
L
C
R
F
M
-
F
V
Y
L
----
V
F
L
F
G
F
S
T
A
V
V
T
L
I
E
D
G
-------
K
Y
N
S
L
----
Y
S
T
C
L
E
L
F
K
F
T
I
G
M
G
D
L
E
F
--
T
E
N
Y
D
F
K
A
-
V
F
I
I
L
L
L
A
Y
------
V
I
L
T
Y
I
L
-----------
L
L
N
M
L
I
A
L
M
-----------------
G
E
T
V
N
K
----
I
A
Q
--
E
S
K
N
---------
I
W
K
L
----------
Q
R
A
I
--
T
I
L
D
T
E
K
S
F
L
K
C
M
R
K
A
U
N
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
65.28
19%
-16
- C5 -
4Z2T
1
?
A:
[11-591]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AETD
V
L
I
V
G
A
G
P
A
G
A
M
S
A
T
L
L
A
-
S
L
-----
G
I
-
R
S
L
-------
M
I
N
R
W
-----
R
--
S
T
S
-----------
P
G
---------------------------
P
R
S
H
I
I
N
Q
R
T
M
E
I
L
R
D
I
----
G
L
E
-------------
E
S
A
K
S
L
A
V
P
K
E
Y
M
G
E
H
V
Y
A
T
S
------
L
A
G
-----
E
E
F
G
R
I
--
P
A
W
A
S
H
P
Q
A
H
A
E
H
E
L
A
S
P
S
R
-----
Y
--------
C
D
----
L
P
--
Q
L
Y
F
E
P
M
V
V
----
S
E
A
A
L
R
G
A
D
V
R
----
F
L
T
E
Y
L
G
H
V
E
D
Q
D
G
V
T
A
R
L
L
D
H
---
V
S
G
--
A
E
Y
E
V
R
A
K
Y
I
I
G
A
D
G
A
H
S
L
V
A
Q
N
A
G
L
P
F
E
G
QM
G
G
S
I
N
--
I
E
F
S
--------
A
------
D
L
S
S
L
C
E
H
R
K
GD
M
Y
Y
M
F
V
A
A
L
R
M
I
R
P
-------
W
N
K
W
I
C
V
W
G
E
I
T
K
E
E
A
K
K
-------
I
I
H
E
I
I
G
T
------
D
E
I
P
V
E
V
G
P
I
S
T
W
T
-----
I
N
Q
Q
Y
A
V
R
-------------
N
T
S
G
R
V
F
C
M
G
D
A
V
--
H
R
H
T
PMGGL
G
L
--
N
T
S
V
Q
D
A
-
Y
N
L
A
W
K
L
A
L
-
V
L
-
K
G
T
A
A
P
-----------
T
L
L
D
S
Y
D
A
E
R
S
----
P
V
A
K
Q
I
----
V
--
E
R
A
F
------
K
S
L
S
T
F
P
P
V
F
E
A
L
SLP
P
A
P
T
E
S
E
M
A
E
A
L
V
R
L
K
D
A
--------------------
S
E
E
G
A
K
R
R
A
A
L
R
K
A
M
D
A
T
I
I
G
L
G
-
G
G
H
G
V
E
L
N
Q
-
R
-----
Y
V
S
R
A
V
F
P
D
G
T
P
D
P
----
G
F
V
R
D
Q
E
F
F
Y
Q
A
S
T
R
P
G
-------
A
H
L
P
H
----
V
W
L
T
E
N
-
Q
R
R
I
S
T
L
D
L
C
G
K
--
G
R
F
T
L
L
T
G
-
L
S
G
A
A
W
K
H
E
------
A
E
Q
V
S
Q
S
L
G
I
E
L
K
V
C
VIG
P
G
Q
E
F
V
D
T
Y
-----------------
G
E
Y
A
K
I
----
S
E
I
G
E
S
G
A
L
---------
L
V
R
P
DMFIAFRAKD
A
S
R
E
--
G
L
E
Q
L
N
V
A
V
K
S
I
L
G
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
64.23
15%
-34
- C1 -
4LLG
-
RPOD_ECOLI
F:
[6-612]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
Q
L
K
L
L
V
T
R
G
K
E
Q
G
Y
L
-
T
Y
A
E
V
N
D
H
L
P
E
D
I
-------
V
D
S
D
Q
-----
I
--
E
D
I
-----------
I
Q
M
I
N
D
M
G
I
Q
V
M
---
G
R
TTDP
V
R
M
Y
M
R
E
M
G
T
V
E
L
L
T
R
E
G
E
I
D
I
A
K
R
I
E
D
G
I
N
Q
-------------
V
Q
C
S
V
A
E
Y
P
E
A
I
T
Y
L
L
E
Q
Y
D
R
------
V
E
A
E
---
E
A
R
L
S
D
L
--
I
T
G
F
V
D
D
-------
P
E
L
A
R
E
-----
K
F
A
E
---
L
R
A
Q
----
Y
V
V
T
R
D
T
I
--
K
A
T
----
A
Q
E
E
I
L
K
L
S
E
V
----
F
K
Q
F
R
----------
L
V
P
K
Q
F
D
---
Y
L
V
--
N
S
M
R
V
M
M
D
R
V
R
T
Q
E
R
L
I
M
K
L
C
--------------------
V
E
--------
Q
------
C
K
M
P
K
K
N
F
I
T
-----
L
F
T
--
G
N
E
T
S
D
-------
T
--
W
F
N
A
A
I
A
M
N
K
P
W
S
E
K
-------
L
H
D
V
S
E
E
V
------
H
R
A
L
Q
K
L
Q
Q
I
E
E
E
T
G
L
-----
T
I
E
Q
V
K
-------------
D
I
N
R
R
M
S
I
G
E
A
K
A
--
R
R
-------
A
K
--
K
E
M
V
E
A
N
-
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
-----------
D
L
I
Q
E
G
N
I
G
L
M
----
K
A
V
D
K
F
E
------
Y
R
R
G
------
Y
K
F
S
T
Y
---
A
T
W
W
---
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
-----
H
M
----------
I
E
T
I
N
K
L
N
R
I
S
-
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
-------
E
-
L
-----
A
E
R
M
L
M
P
E
D
-
K
I
R
K
----
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
-------
D
E
D
S
H
----
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
--
E
S
L
R
A
A
T
H
-
D
V
L
A
G
L
T
A
R
------
E
A
K
V
L
R
M
-----------
R
F
G
I
D
M
N
T
D
-----------------
Y
T
L
E
E
V
----
G
K
Q
F
D
V
T
R
E
---------
R
I
R
Q
----------
I
E
A
K
--
A
L
R
K
L
R
H
P
S
R
S
E
V
L
R
S
F
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
60.91
16%
-54
- C2 -
4WRT
2
?
B:
[10-758]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNINPYF
L
F
I
D
V
PIQAAISTTFPYTGV
P
P
Y
S
H
G
T
G
T
G
Y
T
I
D
T
V
I
R
-
T
H
E
Y
S
N
K
G
K
-
Q
Y
I
S
DVTG
C
T
M
V
D
P
T
-----
N
--
G
P
L
PEDNEPSAYAQ
L
D
C
V
L
E
A
L
D
R
M
D
---
E
E
------
H
P
G
L
F
Q
A
A
S
Q
N
A
M
E
T
L
M
V
T
T
V
D
K
L
T
Q
G
R
Q
T
-------------
F
D
W
T
V
C
R
N
Q
P
A
A
T
A
L
N
T
T
I
T
S
------
F
R
L
N
---
D
L
N
G
A
D
K
GG
L
I
P
F
C
Q
D
I
I
D
S
L
D
R
P
E
M
--
T
-----
F
F
S
V
---
K
N
I
K
----
K
K
L
P
A
K
N
R
K
G
F
L
I
----
K
R
I
P
M
K
V
K
D
K
I
----
T
K
V
E
Y
------
I
K
R
A
L
S
L
N
T
M
T
---
K
D
A
--
E
R
G
K
L
K
R
R
A
I
A
T
A
-----
G
I
Q
I
R
G
-
F
V
L
V
V
--
E
N
L
A
K
--
N
I
C
E
--------
N
LEQSGL
P
V
G
G
N
E
K
K
A
K
-----
L
S
N
A
V
A
K
M
L
S
N
CPPG
G
I
S
M
--
T
V
T
G
D
N
T
K
W
N
E
C
L
N
P
-------
R
I
F
L
A
M
T
E
------
R
I
T
R
D
S
P
I
W
F
R
D
F
C
S
I
A
P
V
L
F
S
N
K
I
A
R
LGK
G
F
M
I
T
S
KTKR
L
K
A
Q
I
P
C
P
D
L
F
S
I
P-
L
E
-------
R
Y
--
N
E
E
T
R
A
K
-
L
K
K
L
K
P
F
F
N
---
E
E
G
T
A
S
L
------------
S
P
G
M
M
M
G
M
F
N
----
M
L
S
T
V
L
G
V
A
A
L
G
I
K
N
I
G
NKE
Y
L
W
D
G
L
Q
S
S
D
D
F
A
L
F
V
---
N
A
K
D
E
E
T
C
M
E
G
I
N
D
F
Y
R
T
C
K
-----
L
L
G
I
N
M
S
KKK
S
Y
C
N
E
T
G
M
F
E
F
T
S
-
M
F
Y
R
D
G
F
V
S
N
F
A
M
E
L
P
S
F
G
V
A
G
-
V
N
E
S
A
D
M
A
I
G
M
T
I
I
K
-
N
N
M
I
NNGM
G
P
A
T
A
Q
T
A
I
Q
L
F
I
A
D
Y
R
-------
Y
T
Y
K
C
HRGD
S
K
V
E
G
K
R
M
K
I
I
K
E
L
W
E
N
T
K
--
G
R
D
G
L
L
V
A
D
G
G
P
N
I
Y
N
L
R
NLHIP
E
I
V
L
K
Y
N
L
-----------
M
D
P
E
Y
K
G
R
L
L
HPQNPFVGHLSIEGIK
E
A
D
I
T
K
----
M
D
Y
D
A
V
S
G
T
HS
W
R
T
K
R
NR
S
I
L
N
----------
T
D
Q
R
--
N
M
I
L
E
E
Q
C
Y
A
K
C
C
N
L
F
E
A
C
F
NSASY
R
K
P
V
G
QHS
M
L
E
A
M
A
H
R
L
R
M
D
A
R
L
D
Y
E
S
GRMS
K
D
D
F
E
K
A
M
A
H
L
G
E
I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
60.64
17%
-47
* C7 *
4PE2
2
MALE_ECOLI
A:
[3-498]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
G
K
L
V
I
W
I
N
G
D
K
G
Y
N
-
G
L
A
E
V
G
K
K
F
-
E
K
D
TG
I
----
K
V
T
V
E
-----
H
--
P
D
K
-----------
L
E
E
K
F
P
Q
V
A
A
T
G
---
D
G
------
P
D
I
I
F
W
A
H
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
----------------------
K
A
F
Q
D
K
L
Y
--
P
F
T
W
D
A
------
V
R
Y
N
---
G
K
L
I
A
-----
Y
P
I
A
V
E
--------
A
L
--
S
-----
L
I
Y
N
---
K
D
L
-----
L
P
N
P
P
K
T
-----------
W
E
E
I
P
A
L
D
K
E
----
L
K
A
K
G
------
K
S
A
L
M
F
N
L
Q
E
P
---
Y
F
T
--
W
P
L
I
A
A
D
G
G
Y
A
-
F
K
Y
E
N
G
K
Y
D
I
K
D
-
V
G
V
D
N
--
A
G
A
K
A
--
G
L
T
F
--------
L
------
V
D
L
I
K
N
K
H
-----------
M
N
A
D
T
D
Y
-------
S
--
I
A
E
A
A
F
N
K
G
E
T
A
M
T
I
-------
N
G
P
W
A
W
S
N
------
I
D
T
S
K
V
N
Y
G
V
T
V
L
P
T
F
K
-----------------------------
G
Q
P
S
K
P
F
--
V
G
-------
V
L
--
S
A
G
I
N
A
A
-
S
P
N
K
E
L
A
K
E
-
F
L
E
N
Y
L
L
T
D
-----------
E
G
L
E
A
V
N
K
D
---------
K
P
L
G
A
V
A
L
--
K
S
Y
E
------
E
E
L
A
K
D
P
R
I
A
A
T
M
---
E
N
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
-----
A
V
----------
R
T
A
V
I
N
A
A
S
G
------
R
Q
T
V
D
E
A
L
K
D
A
Q
T
N
A
A
A
S
N
I
-----
N
K
A
K
V
A
S
V
E
-
S
D
Y
S
----
S
V
K
S
A
--
A
L
S
Y
Y
S
D
K
N
T
MPPSGEL
D
A
L
E
T
----
Y
M
D
T
L
P
D
K
A
D
I
G
G
G
Y
K
L
L
L
V
N
N
K
L
A
L
K
I
G
----
D
G
T
A
A
D
------
S
V
T
---------------
L
T
K
A
Q
I
E
K
L
-----------------
L
S
D
I
G
P
----
K
K
I
Y
T
E
N
T
-----------
L
K
T
----------
E
L
Q
K
--
N
----
S
T
L
K
D
G
T
L
Y
I
V
L
I
D
N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
57.15
13%
-63
- C6 -
2LP4
-
CHEA_ECOLI
A:
[12-128]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
D
E
A
D
E
-
L
L
A
D
M
E
Q
H
L
-
L
D
L
-------
V
P
E
S
P
-----
D
--
A
E
Q
-----------
L
N
A
I
F
R
A
A
H
S
I
K
---
G
G
------
A
G
T
F
G
F
T
I
L
Q
E
T
T
H
L
M
E
N
L
L
D
E
A
R
R
G
E
M
Q
L
-------------
N
T
D
I
I
N
L
F
L
E
T
K
D
I
M
Q
E
Q
L
D
A
------
Y
K
N
S
---
E
E
P
D
A
A
S
--
F
E
Y
I
C
N
A
L
R
Q
L
A
L
E
A
K
G
E
T
P
-----
S
A
V
T
---
R
L
S
V
----
V
A
K
S
E
P
Q
D
E
Q
S
R
S
----
Q
S
P
R
R
I
I
L
S
R
L
----
K
A
G
E
V
------
D
L
L
E
E
E
L
G
H
L
T
---
T
L
T
--
D
V
V
K
G
A
D
S
L
S
A
I
L
P
G
D
I
A
E
D
D
I
T
A
-
V
L
C
F
V
--
I
E
A
D
Q
--
I
T
F
E
--------
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
56.72
15%
-35
- C8 -
4MGR
3
GABR_BACSU
A:
[2-469]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
T
I
T
L
D
R
S
E
Q
A
D
Y
I
Y
Q
Q
I
Y
Q
K
L
-
K
K
E
-------
I
L
S
R
N
-----
L
LP
H
S
K
-----------
V
P
S
K
R
E
L
A
E
N
L
K
---
V
S
------
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
--
K
G
F
F
V
E
-------------
E
L
D
M
F
S
A
E
E
H
P
P
F
A
L
P
D
D
L
K
E
------
I
H
I
D
---
Q
S
D
W
---------
I
S
F
S
H
M
S
S
D
T
D
H
F
P
I
K
-----
S
W
F
R
---
C
E
Q
K
----
A
A
S
R
S
Y
R
T
L
G
D
M
S
----
H
P
Q
G
I
Y
E
V
R
A
A
----
I
T
R
L
I
------
S
L
T
R
G
V
K
C
R
P
E
---
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
L
---------------
L
P
--
K
E
A
V
Y
--
A
M
E
E
--------
P
---------
G
Y
R
R
M
Y
Q
-----
L
L
K
N
A
G
K
Q
V
K
T
-------
I
--
M
L
D
E
K
G
M
S
I
A
E
I
T
R
Q
-------
Q
P
D
V
L
V
T
T
PSHQFP
S
G
T
I
M
P
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
P
R
R
Y
I
I
E
-------------
D
D
Y
D
S
E
F
T
Y
D
V
D
S
--
I
P
-------
A
L
--
Q
S
L
D
R
F
Q
---------
N
-
V
I
Y
M
G
T
F
S
K
-----------
S
L
L
P
G
L
R
I
S
Y
M
V
L
P
P
E
L
L
R
A
Y
K
Q
R
G
Y
--
D
L
Q
T
------
C
S
S
L
T
Q
L
-
T
L
Q
E
F
---
I
E
S
G
------------
E
Y
Q
K
-----
H
I
----------
K
K
M
K
Q
H
Y
K
E
K
R
-
E
R
L
I
T
A
L
E
A
E
F
S
G
E
--------------------
V
T
V
K
-
G
A
N
A
----
G
L
-----
H
F
V
T
E
F
D
T
R
R
-------
T
E
Q
D
I
----
L
S
H
A
A
G
L
Q
-----
L
E
I
F
G
M
--
S
R
F
N
L
K
E
N
-
K
R
Q
T
G
R
P
A
L
------
I
I
G
F
A
R
L
-----------
K
E
E
D
I
Q
E
G
V
-----------------
Q
R
L
F
K
A
----
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
55.21
13%
-30
* C8 *
1K25
-
?
A:
[67-750]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q
I
T
R
T
V
P
A
K
R
G
T
I
Y
D
R
N
G
V
P
-
I
A
E
D
A
T
S
Y
N
-
V
Y
A
-------
V
T
T
S
P
N
R
S
YP
N
--
G
Q
F
-----------
A
S
S
F
I
G
L
A
Q
L
H
E
N
ED
G
S
------
K
S
L
L
G
T
S
G
M
E
S
S
L
N
S
I
L
A
G
T
D
G
I
I
T
Y
G
N
I
V
PGTELVSQQTVD
G
K
D
V
Y
T
T
L
S
S
P
L
Q
S
F
M
E
T
Q
M
D
A
------
F
L
E
K
V
KG
K
Y
M
T
A
T
L
--
V
S
A
K
T
G
E
I
L
A
T
T
Q
R
P
----
T
-----
F
N
A
D
---
T
K
E
G
----
I
T
E
D
F
V
W
R
D
I
L
Y
Q
----
S
N
Y
E
P
G
-----------
S
A
M
------
K
V
M
T
L
A
S
S
I
D
N
---
N
T
F
--
P
S
----
G
E
Y
F
N
S
S
E
L
S
S
N
V
G
M
S
L
L
-
E
Q
K
M
G
--
D
A
T
W
L
--
D
Y
L
K
R
F
KFGVPT
R
------
F
G
L
T
D
E
Y
A
G
Q
-----
L
P
A
D
N
I
V
S
I
A
Q
-------
S
--
S
F
G
Q
G
I
S
V
T
Q
T
Q
M
L
R
-------
A
F
T
A
I
A
-
N
------
D
G
V
M
L
E
P
K
F
I
S
A
I
Y
D
T
N
N
Q
S
V
R
K
S
Q
K
E
-------------
I
V
G
N
P
V
S
K
E
A
A
S
T
--
T
R
-------
N
H
M
I
L
V
G
T
D
P
L
-
I
I
T
V
P
G
Q
N
V
-
A
V
K
S
G
T
A
Q
I
-----------
A
D
E
K
N
G
G
Y
L
V
G
----
S
T
N
Y
I
F
S
A
V
T
M
--
N
P
A
E
------
N
------
P
D
F
I
L
Y
---
V
T
V
Q
----
Q
P
E
H
Y
S
G
I
Q
L
G
E
-----
F
A
----------
T
P
I
L
E
R
A
S
A
M
K
-
E
S
L
N
L
Q
S
P
A
K
N
L
D
K
V
T
T
E
S
S
Y
A
-
M
-----
P
S
I
K
D
I
S
P
G
-
E
L
A
E
----
A
L
R
--
R
N
I
V
Q
P
I
V
V
G
T
G
-------
T
K
I
K
E
----
T
S
V
E
E
G
T
N
L
A
P
N
---------
Q
Q
V
L
L
L
S
D
-
K
------
V
E
------
E
I
P
D
M
Y
G
-----------
W
K
K
E
T
A
E
T
F
-----------------
A
K
W
L
D
I
----
E
L
E
F
E
G
S
G
S
---------
V
V
Q
K
----------
Q
D
V
R
--
T
N
T
A
I
K
N
I
K
--
K
I
K
L
T
L
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
54.90
12%
-47
- C6 -
1I5N
1
CHEA_SALTY
A:
[11-110]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
F
F
D
E
A
D
E
-
L
L
A
D
M
E
Q
H
L
-
L
D
L
-------
V
P
E
S
P
-----
D
--
A
E
Q
-----------
L
N
A
I
F
R
A
A
H
S
I
K
---
G
G
------
A
G
T
F
G
F
T
I
L
Q
E
T
T
H
L
M
E
N
L
L
D
E
A
R
R
G
E
M
Q
L
-------------
N
T
D
I
I
N
L
F
L
E
T
K
D
I
M
Q
E
Q
L
D
A
------
Y
K
N
S
---
E
E
P
D
A
A
S
--
F
E
Y
I
C
N
A
L
R
Q
L
A
L
E
A
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
53.74
8%
-58
- C6 -
2LCH
-
?
A:
[7-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
K
K
V
T
D
E
L
K
E
-
L
I
Q
N
V
N
D
D
I
-
K
E
V
-------
E
K
N
P
E
-----
D
--
M
E
Y
-----------
W
N
K
I
Y
R
L
V
H
T
M
K
---
E
I
------
T
E
T
M
G
F
S
S
V
A
K
V
L
H
T
I
M
N
L
V
D
K
M
L
N
S
E
I
K
I
-------------
T
S
D
L
I
D
K
V
K
K
K
L
D
M
V
T
R
E
L
D
K
------
K
V
S
G
---
S
Y
L
V
P
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
52.89
11%
-53
- C6 -
1TQG
-
CHEA_THEMA
A:
[9-102]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
D
E
T
K
E
-
Y
L
Q
N
L
N
D
T
L
-
L
E
L
-------
E
K
N
P
E
-----
D
--
M
E
L
-----------
I
N
E
A
F
R
A
L
H
T
L
K
---
G
M
------
A
G
T
M
G
F
S
S
M
A
K
L
C
H
T
L
E
N
I
L
D
K
A
R
N
S
E
I
K
I
-------------
T
S
D
L
L
D
K
I
F
A
G
V
D
M
I
T
R
M
V
D
K
------
I
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
52.51
17%
-43
- C6 -
3KYJ
1
?
A:
[17-116]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
D
G
A
Q
-
A
L
D
A
M
E
A
S
L
-
L
A
L
-------
Q
A
G
E
D
-----
A
--
A
A
H
-----------
V
G
P
L
F
R
A
V
H
T
F
K
---
G
N
------
S
R
V
L
G
L
S
V
V
E
S
R
A
H
L
C
E
D
L
I
G
L
V
R
D
A
G
V
P
M
-------------
D
G
E
I
V
E
I
L
L
F
A
S
D
T
L
R
A
M
L
E
E
------
T
A
A
S
---
R
A
D
V
E
G
T
--
G
S
E
A
L
M
D
Q
L
R
S
K
I
A
R
C
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
52.37
10%
-56
- C6 -
2LD6
-
CHEA_THEMA
A:
[10-107]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
E
T
K
E
-
Y
L
Q
N
L
N
D
T
L
-
L
E
L
-------
E
K
N
P
E
-----
D
--
M
E
L
-----------
I
N
E
A
F
R
A
L
H
T
L
K
---
G
M
------
A
G
T
M
G
F
S
S
M
A
K
L
C
H
T
L
E
N
I
L
D
K
A
R
N
S
E
I
K
I
-------------
T
S
D
L
L
D
K
I
F
A
G
V
D
M
I
T
R
M
V
D
K
------
I
V
S
E
---
G
S
D
D
I
G
E
--
N
I
D
V
F
S
D
T
I
K
S
F
A
S
S
G
K
E
K
L
-----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
52.03
16%
-62
- C6 -
3KYJ
1
?
A:
[9-113]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-----
D
E
I
W
A
L
Y
A
D
-
D
G
A
Q
----
A
L
D
A
M
E
A
S
L
L
A
L
Q
A
G
E
D
-------
A
A
A
H
V
----
G
P
L
F
R
A
V
H
T
F
K
G
N
S
R
V
L
G
L
--
S
V
V
E
S
R
A
H
-
L
C
E
D
L
I
G
L
V
------
R
-
D
A
G
V
P
-----------
M
D
G
E
I
V
E
I
L
-----------------
L
F
A
S
D
T
----
L
R
A
M
L
E
E
T
A
---------
A
S
R
A
----------
D
V
E
G
--
T
G
S
E
A
L
M
D
Q
L
R
S
K
I
A
R
C
S
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
50.54
12%
-63
- C6 -
2LD6
-
CHEA_THEMA
A:
[4-106]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
L
G
V
F
V
D
-
E
T
K
E
----
Y
L
Q
N
L
N
D
T
L
L
E
L
E
K
N
P
E
-------
D
M
E
L
I
----
N
E
A
F
R
A
L
H
T
L
K
G
M
A
G
T
M
G
F
--
S
S
M
A
K
L
C
H
-
T
L
E
N
I
L
D
K
A
------
R
N
S
E
-
I
K
-----------
I
T
S
D
L
L
D
K
I
-----------------
F
A
G
V
D
M
----
I
T
R
M
V
D
K
I
V
---------
S
E
G
S
----------
D
D
I
G
--
E
N
I
D
V
F
S
D
T
I
K
S
F
A
S
S
G
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
48.92
10%
-60
- C6 -
2LP4
-
CHEA_ECOLI
A:
[5-109]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
S
D
F
Y
Q
T
F
F
D
-
E
A
D
E
----
L
L
A
D
M
E
Q
H
L
L
D
L
V
P
E
S
P
-------
D
A
E
Q
L
----
N
A
I
F
R
A
A
H
S
I
K
G
G
A
G
T
F
G
F
--
T
I
L
Q
E
T
T
H
-
L
M
E
N
L
L
D
E
A
------
R
R
-
G
E
M
Q
-----------
L
N
T
D
I
I
N
L
F
-----------------
L
E
T
K
D
I
----
M
Q
E
Q
L
D
A
Y
K
---------
N
S
E
E
----------
P
D
A
A
--
S
F
E
Y
I
C
N
A
L
R
Q
L
A
L
E
A
K
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
48.59
9%
-56
- C6 -
1I5N
1
CHEA_SALTY
A:
[5-110]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
S
D
F
Y
Q
T
F
F
D
-
E
A
D
E
----
L
L
A
D
M
E
Q
H
L
L
D
L
V
P
E
S
P
-------
D
A
E
Q
L
----
N
A
I
F
R
A
A
H
S
I
K
G
G
A
G
T
F
G
F
--
T
I
L
Q
E
T
T
H
-
L
M
E
N
L
L
D
E
A
------
R
R
G
E
-
M
Q
-----------
L
N
T
D
I
I
N
L
F
-----------------
L
E
T
K
D
I
----
M
Q
E
Q
L
D
A
Y
K
---------
N
S
E
E
----------
P
D
A
A
--
S
F
E
Y
I
C
N
A
L
R
Q
L
A
L
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
48.07
15%
-33
- C4 -
4M8O
7
DPOE_YEAST
A:
[31-1186]
A
L
S
A
Q
Q
L
L
N
A
S
K
I
D
D
I
D
S
M
M
GF
E
R
Y
V
P
P
QYNGRFDAKDIDQ
I
P
G
R
V
G
WLT
N
M
H
A
T
L
V
S
QEVTTN
Q
G
I
S
G
V
D
F
Y
F
L
D
EEG
G
S
F
K
S
T
V
V
Y
D
P
Y
F
F
I
A
C
NDESR
V
N
D
V
E
E
L
V
K
K
Y
L
ESCLK
S
L
Q
I
I
R
K
E
D
LTMDNHLLG
L
Q
K
T
L
I
K
L
S
F
VN
S
N
Q
L
F
E
A
R
K
L
L
R
P
I
L
Q
D
N
A
N
N
N
V
Q
R
NIYNVKVDAKHLIEDIREYDVP
Y
H
V
R
V
S
I
D
K
DIRVG
K
W
Y
K
V
T
QQGFIEDTRKIAFADPV
V
M
A
F
A
I
A
T
T
K
P
P
LKFPDSAVDQIM
M
I
S
Y
M
I
DG
E
G
F
L
I
T
N
REIISEDI
E
D
F
E
Y
T
PKPE
Y
P
G
F
F
T
I
F
NEND
E
V
A
L
L
Q
R
F
F
E
H
I
R
D
V
RPT
V
I
S
T
F
NGDFF
D
W
P
F
I
H
N
R
S
K
I
H
GLDMFDEIG
F
A
P
D
AEG
E
Y
K
S
S
Y
C
S
H
M
D
C
F
R
W
V
K
R
D
S
Y
---
L
P
Q
G
S
Q
G
L
-
K
A
V
-------
T
Q
S
K
L
-----
G
--
Y
N
P
-----------
I
-------------------------------
E
L
D
P
E
L
M
T
P
Y
A
F
E
K
P
Q
H
L
S
E
Y
-------------
S
V
S
D
A
V
A
---
T
Y
Y
L
Y
M
K
Y
V
H
P
------
F
I
F
S
---
L
C
T
I
------
I
P
L
N
P
D
E
T
L
R
K
G
T
G
T
L
C
E
M
-----
L
L
M
V
---
Q
A
Y
Q
H
N
I
L
L
P
N
K
H
T
D
P
I
E
R
F
Y
----
D
G
H
L
L
E
S
E
T
Y
V
----
G
G
H
V
E
------
S
L
E
A
-
G
V
F
R
S
----
D
L
K
--
N
E
F
K
I
D
P
S
A
I
D
E
L
L
Q
E
L
P
E
A
L
K
F
S
-
V
E
V
E
N
--
K
S
S
V
D
--
K
V
T
N
--------
F
------
E
E
I
K
N
Q
I
T
Q
K
-----
L
L
E
L
K
E
N
N
I
R
N
-------
E
--
L
-------------
P
-------
L
I
Y
H
V
D
V
A
------
S
--------------
M
Y
P
N
I
M
T
T
N
R
L
Q
-------------
P
D
S
I
K
A
E
R
D
C
A
S
C
TC
A
R
-------
K
L
--
K
W
A
W
R
G
E
F
F
P
S
K
M
D
E
Y
N
-
M
I
K
R
A
L
Q
N
------------
E
T
F
P
N
K
N
K
F
S
K
----
K
K
V
L
T
F
D
E
L
S
-----------------------------
Y
A
D
Q
V
I
H
I
K
K
R
L
T
E
Y
S
R
K
V
Y
-----
H
-------------------
R
V
K
-
V
S
E
I
V
E
R
E
A
I
V
C
Q
R
E
N
P
F
Y
V
D
T
-
V
-----
K
S
F
R
D
R
R
Y
E
-
F
K
G
L
----
A
K
T
W
K
G
N
L
S
K
I
D
P
S
D
K
H
-------
A
R
D
E
A
----
K
K
M
I
V
L
Y
D
S
L
Q
L
A
H
K
V
I
L
N
--
S
F
Y
G
Y
V
M
R
-
K
G
S
R
W
Y
S
M
E
------
M
A
G
I
T
C
L
-----------
T
G
A
T
I
I
Q
M
A
-----------------
R
A
L
V
E
R
V
G
R
P
L
E
L
D
T
D
G
I
W
---------
C
I
L
P
----------
K
S
F
P
E
T
Y
F
F
T
L
E
N
G
K
K
L
Y
L
S
Y
P
C
S
M
L
N
Y
R
V
H
Q
K
FTNHQYQELKDPLNY
I
Y
E
T
H
S
E
N
T
I
F
F
E
V
D
G
PYK
A
M
I
L
P
S
S
KEEG
K
G
I
K
K
R
Y
A
V
F
N
EDGSLAELKGFELKRRGEL
Q
L
I
K
N
F
Q
S
D
I
FKVFLEGDT
L
E
G
C
Y
S
A
V
A
S
V
C
N
R
W
L
D
V
L
D
S
HGLMLE
D
E
D
L
V
S
L
I
C
E
N
R
S
MSKTLKEYEGQKS
T
S
I
T
T
A
R
R
L
G
D
F
LGEDMVKDKG
L
Q
C
K
Y
I
I
S
SKPFNAPVTERAIPVAIFSAD
I
P
I
K
R
S
F
L
R
R
W
T
LDPSLEDLDIRTIID
W
G
Y
Y
R
E
R
L
G
S
A
I
Q
K
I
IT
I
P
A
A
L
Q
GVSNPVPRVEHP
D
W
L
K
R
K
I
AT
15
HHSearch
47.71
12%
-55
- C6 -
1TQG
-
CHEA_THEMA
A:
[4-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
L
G
V
F
V
D
-
E
T
K
E
----
Y
L
Q
N
L
N
D
T
L
L
E
L
E
K
N
P
E
-------
D
M
E
L
I
----
N
E
A
F
R
A
L
H
T
L
K
G
M
A
G
T
M
G
F
--
S
S
M
A
K
L
C
H
-
T
L
E
N
I
L
D
K
A
------
R
N
S
E
-
I
K
-----------
I
T
S
D
L
L
D
K
I
-----------------
F
A
G
V
D
M
----
I
T
R
M
V
D
K
I
V
---------
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
46.16
13%
-28
- C6 -
2OOC
2
?
A:
[28-111]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
V
L
A
L
-
F
R
E
Q
A
A
L
W
A
-
P
-
M
-------
L
D
------------
P
T
-----------
H
P
G
W
K
D
A
V
H
T
V
K
---
G
A
------
A
R
G
V
G
A
F
N
L
G
E
V
C
E
R
C
E
A
G
Q
E
--------
S
-------------
L
E
G
V
R
T
A
L
D
A
A
L
L
D
I
A
A
Y
A
H
E
------
Q
A
L
R
---
S
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------