@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2892: (2016-02-11 )
MSLHGKTLFITGASRGIGREIALRAARDGANLVIAAKSAEPHPKLEGTIFSVAAEVEAAGGQALPLQLDVRDEQAVAAAMARAAERFGGIDALVNNAGAIRLVGVEKLEPKRFDLMYQINTRAVLVCSQAALPYLRRSANGHILSLSPPINLAGRWFAQHGPYTVTKYGMSMLTLGMHEEFGKYAISVNALWPKTMIATAAIEFELGSRDAFRRARTPAIMADAAHAILTSEGRSLSGRLLVDEELLRERGQSDFEQYRYDPEGGALVPDLFLD
Atome Classification :
(21 SA)
.........10........20........30....--....40........50.....-..-..60........70........80......------..90........100.---......110.......120.......130....------..-.140.......150.......160-.......170.......180.......190.--.....--.200.....-------------------.---------.210....--...-------220.......230.......-240-.......-----.250.......260-.......270..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSLHG
K
T
L
F
I
TGASRGI
G
R
E
I
A
L
R
AARDGA
N
L
V
I
A
--AKSAEPHPKLE
G
T
I
F
-
S
V
A
A
E
-
V
E-AAGG
Q
A
L
P
L
Q
L
DVR
D
E
Q
A
V
A
A
A
M
A
R
A
A
E
R
F------G
G
I
D
A
L
VNNA
G
A
I
R
L
V
---
G
VEKLEPK
R
F
D
L
M
Y
Q
IN
T
R
A
V
L
V
C
S
Q
A
A
L
P
Y
L
R
------RS-ANG
H
I
L
SLSPPI
N
L
A
G
R
W
FAQHGP-
Y
T
V
T
K
Y
G
M
S
M
L
T
L
G
M
H
E
E
FG
K
Y
A
I
S
V
NALWP--K
T
M
I
A
--
T
A
A
I
E
F
ELG-------------------S---------
R
D
A
F
R
RAR--T
P
A
-------
I
M
A
D
A
A
H
A
I
L
TSEGRSLS
G
R
-
L
-
L
-V
D
E
E
L
L
R
-----ERG
Q
S
D
F
E
Q
YRYDP-EG
G
A
LVPDLFLD
1
PsiBlast_PDB
95.36
54%
-97
- C1 -
3KVO
2
HSDL2_HUMAN
A:
[43-310]
--
L
A
G
C
T
V
F
I
T
G
A
S
R
G
I
G
K
A
I
A
L
K
A
A
K
D
G
A
N
I
V
I
A
--
A
K
T
A
Q
P
H
P
K
L
L
G
T
I
Y
-
T
A
A
E
E
-
I
E
-
A
V
G
G
K
A
L
P
C
I
V
D
V
R
D
E
Q
Q
I
S
A
A
V
E
K
A
I
K
K
F
------
G
G
I
D
I
L
V
N
N
A
S
A
I
S
L
T
---
N
T
L
D
T
P
T
K
R
L
D
L
M
M
N
V
N
T
R
G
T
Y
L
A
S
K
A
C
I
P
Y
L
K
------
K
S
-
K
V
A
H
I
L
N
I
S
P
P
L
N
L
N
P
V
W
F
K
Q
H
C
A
-
Y
T
I
A
K
Y
G
M
S
M
Y
V
L
G
M
A
E
E
F
-
K
G
E
I
A
V
N
A
L
W
P
--
K
T
A
I
H
--
T
A
A
M
D
M
-
L
G
------------------------------
G
I
E
S
Q
C
R
--
K
V
D
-------
I
I
A
D
A
A
Y
S
I
F
-
Q
K
P
K
S
F
T
G
N
-
F
-
V
-
I
D
E
N
I
L
K
-----
E
E
G
I
E
N
F
D
V
Y
A
I
K
P
--
G
H
P
L
Q
P
D
F
F
L
D
21
PsiBlast_CBE
95.27
54%
-98
- C1 -
3KVO
2
HSDL2_HUMAN
B:
[43-310]
--
L
A
G
C
T
V
F
I
T
G
A
S
R
G
I
G
K
A
I
A
L
K
A
A
K
D
G
A
N
I
V
I
A
--
A
K
T
A
Q
P
H
P
K
L
L
G
T
I
Y
-
T
A
A
E
E
-
I
E
-
A
V
G
G
K
A
L
P
C
I
V
D
V
R
D
E
Q
Q
I
S
A
A
V
E
K
A
I
K
K
F
------
G
G
I
D
I
L
V
N
N
A
S
A
I
S
L
T
---
N
T
L
D
T
P
T
K
R
L
D
L
M
M
N
V
N
T
R
G
T
Y
L
A
S
K
A
C
I
P
Y
L
K
------
K
S
-
K
V
A
H
I
L
N
I
S
P
P
L
N
L
N
P
V
W
F
K
Q
H
C
A
-
Y
T
I
A
K
Y
G
M
S
M
Y
V
L
G
M
A
E
E
F
-
K
G
E
I
A
V
N
A
L
W
P
--
K
T
A
I
H
--
T
A
A
M
D
M
-
L
G
-------------------
G
---------
P
G
I
E
S
Q
C
R
--
K
V
D
-------
I
I
A
D
A
A
Y
S
I
F
-
Q
K
P
K
S
F
T
G
N
-
F
-
V
-
I
D
E
N
I
L
K
-----
E
E
G
I
E
N
F
D
V
Y
A
I
K
P
--
G
H
P
L
Q
P
D
F
F
L
D
120
HHSearch
95.02
54%
-98
- C1 -
3KVO
2
HSDL2_HUMAN
A:
[41-309]
G
R
L
A
G
C
T
V
F
I
T
G
A
S
R
G
I
G
K
A
I
A
L
K
A
A
K
D
G
A
N
I
V
I
A
--
A
K
T
A
Q
P
H
P
K
L
L
G
T
I
Y
-
T
A
A
E
E
-
I
E
-
A
V
G
G
K
A
L
P
C
I
V
D
V
R
D
E
Q
Q
I
S
A
A
V
E
K
A
I
K
K
F
------
G
G
I
D
I
L
V
N
N
A
S
A
I
S
L
T
---
N
T
L
D
T
P
T
K
R
L
D
L
M
M
N
V
N
T
R
G
T
Y
L
A
S
K
A
C
I
P
Y
L
K
------
K
S
-
K
V
A
H
I
L
N
I
S
P
P
L
N
L
N
P
V
W
F
K
Q
H
C
A
-
Y
T
I
A
K
Y
G
M
S
M
Y
V
L
G
M
A
E
E
F
K
G
-
E
I
A
V
N
A
L
W
P
--
K
T
A
I
H
--
T
A
A
M
-
D
M
L
G
------------------------------
G
I
E
S
Q
C
R
--
K
V
D
-------
I
I
A
D
A
A
Y
S
I
F
Q
K
P
K
S
-
F
T
G
N
-
F
-
V
-
I
D
E
N
I
L
K
-----
E
E
G
I
E
N
F
D
V
Y
A
I
K
P
--
G
H
P
L
Q
P
D
F
F
L
-
3
PsiBlast_PDB
92.45
49%
-97
- C1 -
3SC4
9
?
A:
[6-275]
-
S
L
R
G
K
T
M
F
I
S
G
G
S
R
G
I
G
L
A
I
A
K
R
V
A
A
D
G
A
N
V
A
L
V
--
A
K
S
A
E
P
H
P
K
L
P
G
T
I
Y
-
T
A
A
K
E
-
I
E
-
E
A
G
G
Q
A
L
P
I
V
G
D
I
R
D
G
D
A
V
A
A
A
V
A
K
T
V
E
Q
F
------
G
G
I
D
I
C
V
N
N
A
S
A
I
N
L
G
---
S
I
E
E
V
P
L
K
R
F
D
L
M
N
G
I
Q
V
R
G
T
Y
A
V
S
Q
S
C
I
P
H
M
K
------
G
R
-
D
N
P
H
I
L
T
L
S
P
P
I
R
L
E
P
K
W
L
-
R
P
T
P
-
Y
M
M
A
K
Y
G
M
T
L
C
A
L
G
I
A
E
E
L
R
D
A
G
I
A
S
N
T
L
W
P
--
R
T
T
V
A
--
T
A
A
V
Q
N
L
L
G
-------------------
G
---------
D
E
A
M
A
R
S
R
--
K
P
E
-------
V
Y
A
D
A
A
Y
V
V
L
-
N
K
P
S
S
Y
T
G
N
-
T
-
L
-
L
C
E
D
V
L
L
-----
E
S
G
V
T
D
L
S
V
Y
D
C
V
P
--
G
S
E
L
G
V
D
L
W
V
D
2
PsiBlast_PDB
91.79
54%
-94
- C1 -
3E03
1
?
A:
[2-272]
L
T
L
S
G
K
T
L
F
I
T
G
A
S
R
G
I
G
L
A
I
A
L
R
A
A
R
D
G
A
N
V
A
I
A
--
A
K
S
A
V
A
N
P
K
L
P
G
T
I
H
-
S
A
A
A
A
-
V
N
-
A
A
G
G
Q
G
L
A
L
K
C
D
I
R
E
E
D
Q
V
R
A
A
V
A
A
T
V
D
T
F
------
G
G
I
D
I
L
V
N
N
A
S
A
I
W
L
R
---
G
T
L
D
T
P
M
K
R
F
D
L
M
Q
Q
V
N
A
R
G
S
F
V
C
A
Q
A
C
L
P
H
L
L
------
Q
A
-
P
N
P
H
I
L
T
L
A
P
P
P
S
L
N
P
A
W
W
G
A
H
T
G
-
Y
T
L
A
K
M
G
M
S
L
V
T
L
G
L
A
A
E
F
G
P
Q
G
V
A
I
N
A
L
W
P
--
R
T
V
I
A
--
T
-------
G
-------------------
V
---------
D
A
A
--
A
C
R
--
R
P
E
-------
I
M
A
D
A
A
H
A
V
L
T
R
E
A
A
G
F
H
G
Q
-
F
-
L
-
I
D
D
E
V
L
A
-----
Q
A
G
I
T
D
L
S
G
Y
A
V
D
P
-
Q
-
R
A
L
L
P
D
L
F
L
E
22
PsiBlast_CBE
91.51
49%
-97
- C1 -
3SC4
6
?
B:
[5-275]
M
S
L
R
G
K
T
M
F
I
S
G
G
S
R
G
I
G
L
A
I
A
K
R
V
A
A
D
G
A
N
V
A
L
V
--
A
K
S
A
E
P
H
P
K
L
P
G
T
I
Y
-
T
A
A
K
E
-
I
E
-
E
A
G
G
Q
A
L
P
I
V
G
D
I
R
D
G
D
A
V
A
A
A
V
A
K
T
V
E
Q
F
------
G
G
I
D
I
C
V
N
N
A
S
A
I
N
L
G
---
S
I
E
E
V
P
L
K
R
F
D
L
M
N
G
I
Q
V
R
G
T
Y
A
V
S
Q
S
C
I
P
H
M
K
------
G
R
-
D
N
P
H
I
L
T
L
S
P
P
I
R
L
E
P
K
W
L
-
R
P
T
P
-
Y
M
M
A
K
Y
G
M
T
L
C
A
L
G
I
A
E
E
L
R
D
A
G
I
A
S
N
T
L
W
P
--
R
T
T
V
A
--
T
A
A
V
Q
N
L
L
G
-------------------
G
---------
D
E
A
M
A
R
S
R
--
K
P
E
-------
V
Y
A
D
A
A
Y
V
V
L
-
N
K
P
S
S
Y
T
G
N
-
T
-
L
-
L
C
E
D
V
L
L
-----
E
S
G
V
T
D
L
S
V
Y
D
C
V
P
--
G
S
E
L
G
V
D
L
W
V
D
126
HHSearch
89.74
50%
-101
- C1 -
3SC4
9
?
A:
[6-264]
-
S
L
R
G
K
T
M
F
I
S
G
G
S
R
G
I
G
L
A
I
A
K
R
V
A
A
D
G
A
N
V
A
L
V
--
A
K
S
A
E
P
H
P
K
L
P
G
T
I
Y
-
T
A
A
K
E
-
I
E
-
E
A
G
G
Q
A
L
P
I
V
G
D
I
R
D
G
D
A
V
A
A
A
V
A
K
T
V
E
Q
F
------
G
G
I
D
I
C
V
N
N
A
S
A
I
N
L
G
---
S
I
E
E
V
P
L
K
R
F
D
L
M
N
G
I
Q
V
R
G
T
Y
A
V
S
Q
S
C
I
P
H
M
K
------
G
R
-
D
N
P
H
I
L
T
L
S
P
P
I
R
L
E
P
K
-
W
L
R
P
T
P
-
Y
M
M
A
K
Y
G
M
T
L
C
A
L
G
I
A
E
E
L
R
D
A
G
I
A
S
N
T
L
W
P
--
R
T
T
V
A
--
T
A
A
V
Q
N
L
L
G
-------------------
G
---------
D
E
A
M
A
R
S
R
--
K
P
E
-------
V
Y
A
D
A
A
Y
V
V
L
N
K
P
S
-
S
Y
T
G
N
-
T
L
L
-
C
E
D
V
L
-
L
-----
E
S
G
V
T
D
L
S
V
Y
D
C
V
P
-------------
41
PsiBlast_CBE
67.33
34%
-101
- C1 -
2JAP
2
?
D:
[4-187]
-
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
--
A
R
R
V
E
K
-------
L
R
-
A
L
G
D
E
-
L
T
-
A
A
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
------
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
---
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
------
R
S
--
K
G
T
V
V
Q
M
S
---
S
I
A
G
R
V
N
V
R
N
A
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
T
E
R
G
V
R
V
V
V
I
E
P
--
G
T
-------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
67.02
34%
-100
- C1 -
2JAP
2
?
C:
[4-187]
-
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
--
A
R
R
V
E
K
-------
L
R
-
A
L
G
D
E
-
L
T
-
A
A
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
------
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
---
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
------
R
S
--
K
G
T
V
V
Q
M
S
---
S
I
A
G
R
V
N
V
R
N
A
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
T
E
R
G
V
R
V
V
V
I
E
P
--
G
T
-------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
66.75
28%
-82
- C1 -
3QLJ
5
?
A:
[25-310]
--
V
D
G
R
V
V
I
V
T
G
A
G
G
G
I
G
R
A
H
A
L
A
F
A
A
E
G
A
R
V
V
V
N
DI
G
V
G
L
D
G
S
P
A
S
G
G
S
A
A
Q
S
V
V
D
E
-
I
T
-
A
A
G
G
E
A
V
A
D
G
S
N
V
A
D
W
D
Q
A
A
G
L
I
Q
T
A
V
E
T
F
------
G
G
L
D
V
L
V
N
N
A
G
I
V
R
D
R
---
M
I
A
N
T
S
E
E
E
F
D
A
V
I
A
V
H
L
K
G
H
F
A
T
M
R
H
A
A
A
Y
W
R
G
L
S
K
A
G
K
A
-
V
D
G
R
I
I
N
T
S
S
G
A
G
L
Q
G
S
--
V
G
Q
G
N
-
Y
S
A
A
K
A
G
I
A
T
L
T
L
V
G
A
A
E
M
G
R
Y
G
V
T
V
N
A
I
A
P
S
A
R
T
R
M
T
--
E
T
V
F
A
E
------------------------------------
F
D
A
M
--
A
P
E
-------
N
V
S
P
L
V
V
W
L
G
S
A
E
A
R
D
V
T
G
K
-
V
-
F
E
V
E
G
G
K
I
R
V
A
E
G
W
A
H
G
P
Q
I
D
K
G
A
R
W
D
P
A
E
L
G
P
V
V
A
D
L
L
--
43
PsiBlast_CBE
66.41
34%
-102
- C1 -
2JAP
2
?
B:
[4-187]
-
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
--
A
R
R
V
E
K
-------
L
R
-
A
L
G
D
E
-
L
T
-
A
A
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
------
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
---
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
------
R
S
--
K
G
T
V
V
Q
M
S
---
S
I
A
G
R
V
N
V
R
N
A
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
T
E
R
G
V
R
V
V
V
I
E
P
--
G
T
-------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
66.12
34%
-101
- C1 -
2JAP
2
?
A:
[4-187]
-
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
--
A
R
R
V
E
K
-------
L
R
-
A
L
G
D
E
-
L
T
-
A
A
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
------
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
---
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
------
R
S
--
K
G
T
V
V
Q
M
S
---
S
I
A
G
R
V
N
V
R
N
A
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
T
E
R
G
V
R
V
V
V
I
E
P
--
G
T
-------------------------------------------------------------------------------------------------------------------------------
121
HHSearch
63.52
29%
-79
- C1 -
3GAF
-
?
A:
[8-253]
-
H
L
N
D
A
V
A
I
V
T
G
A
A
A
G
I
G
R
A
I
A
G
T
F
A
K
A
G
A
S
V
V
V
T
--
D
L
K
S
E
G
A
-------
E
-
A
V
A
A
A
-
I
R
-
Q
A
G
G
K
A
I
G
L
E
C
N
V
T
D
E
Q
H
R
E
A
V
I
K
A
A
L
D
Q
F
------
G
K
I
T
V
L
V
N
N
A
G
G
G
G
P
K
---
P
F
-
D
M
P
M
S
D
F
E
W
A
F
K
L
N
L
F
S
L
F
R
L
S
Q
L
A
A
P
H
M
Q
------
K
A
-
G
G
G
A
I
L
N
I
S
S
M
A
G
E
N
T
N
--
V
R
M
A
S
-
Y
G
S
S
K
A
A
V
N
H
L
T
R
N
I
A
F
D
V
G
P
M
G
I
R
V
N
A
I
A
P
--
G
A
-
I
K
--
T
D
A
L
A
T
V
L
T
-------------------
P
E
I
E
R
A
M
L
K
-
H
T
P
L
G
R
L
G
--
E
A
Q
-------
D
I
A
N
A
A
L
F
L
C
S
P
A
A
A
W
I
S
G
Q
-
V
L
T
-
V
S
G
G
G
V
Q
-----
E
--------------------------
127
HHSearch
63.27
28%
-83
- C1 -
2CFC
2
HCDR_XANP2
A:
[2-248]
----
S
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
--
D
L
S
A
E
T
L
E
E
--------
T
A
R
T
H
W
H
-
A
Y
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
------
G
A
I
D
V
L
V
N
N
A
G
I
T
G
N
S
EAG
V
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
------
L
Q
-
G
A
G
V
I
V
N
I
A
S
V
A
S
L
V
A
F
--
P
G
R
S
A
-
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
--
G
M
-
I
E
--
T
P
M
T
Q
W
R
L
D
-------------------
Q
P
E
L
R
D
Q
V
L
A
R
I
P
Q
K
E
I
G
--
T
A
A
-------
Q
V
A
D
A
V
M
F
L
A
G
E
D
A
T
Y
V
N
G
A
-
A
L
V
-
M
D
G
A
Y
T
---------------------------------
18
PsiBlast_PDB
61.63
27%
-84
- C1 -
3OID
2
FABL_BACSU
A:
[3-241]
---
Q
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
V
I
--------
N
Y
A
R
S
K
K
A
A
L
-
E
T
A
E
E
-
I
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
------
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
R
---
P
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
L
M
E
------
K
N
-
G
G
G
H
I
V
S
I
S
S
L
G
S
I
--
R
Y
L
E
N
Y
T
T
-
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
-
S
--
G
G
A
I
D
--
T
D
A
L
K
H
F
P
N
-------------------
R
---------
E
D
L
L
E
D
A
R
Q
N
T
P
A
GRMVE
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
-
T
-
I
-
I
--------------------------------------
135
HHSearch
61.59
25%
-83
- C1 -
1GEE
1
DHG_BACME
A:
[4-252]
-
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
--
Y
R
S
K
E
D
E
------
A
N
-
S
V
L
E
E
-
I
K
-
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
------
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
---
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
------
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
--
P
L
F
V
H
-
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
--
G
A
-
I
N
--
T
P
I
N
A
E
K
F
A
-------------------
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
--
E
P
E
-------
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
-
T
L
F
-
A
D
G
G
M
T
L
--------------------------------
130
HHSearch
61.14
29%
-79
- C1 -
3ICC
5
?
A:
[3-254]
S
M
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
K
R
L
A
N
D
G
A
L
V
A
I
H
--
Y
G
N
R
K
E
E
------
A
E
-
E
T
V
Y
E
-
I
Q
-
S
N
G
G
S
A
F
S
I
G
A
N
L
E
S
L
H
G
V
E
A
L
Y
S
S
L
D
N
E
L
Q
N
R
TGS
T
K
F
D
I
L
I
N
N
A
G
I
G
P
G
A
---
F
I
E
E
T
T
E
Q
F
F
D
R
M
V
S
V
N
A
K
A
P
F
F
I
I
Q
Q
A
L
S
R
L
R
------
D
---
N
S
R
I
I
N
I
S
S
A
A
T
R
I
S
L
--
P
D
F
I
A
-
Y
S
M
T
K
G
A
I
N
T
M
T
F
T
L
A
K
Q
L
G
A
R
G
I
T
V
N
A
I
L
P
--
G
F
-
V
K
--
T
D
M
N
A
E
L
L
S
-------------------
D
P
M
M
K
Q
Y
A
T
T
I
S
A
F
N
R
L
G
--
E
V
E
-------
D
I
A
D
T
A
A
F
L
A
S
P
D
S
R
W
V
T
G
Q
-
L
-
I
D
V
S
G
G
S
C
---------------------------------
17
PsiBlast_PDB
60.11
27%
-94
- C1 -
3OIC
-
FABL_BACSU
A:
[3-241]
---
Q
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
V
I
--------
N
Y
A
R
S
K
K
A
A
L
-
E
T
A
E
E
-
I
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
------
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
R
---
P
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
L
M
E
------
K
N
-
G
G
G
H
I
V
S
I
S
S
L
G
S
I
--
R
Y
L
E
N
Y
T
T
-
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
-
S
--
G
G
A
I
---------
F
P
N
-------------------
R
---------
E
D
L
L
E
D
A
R
Q
N
T
P
A
GRMVE
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
-
T
-
I
-
I
--------------------------------------
131
HHSearch
58.39
26%
-83
- C1 -
3WDS
4
?
A:
[9-260]
-
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
--
D
L
D
V
M
A
A
Q
--------
A
V
V
A
G
-
L
----
E
N
G
G
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
---
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
------
A
S
N
T
K
G
V
I
V
N
T
A
S
L
A
A
K
V
G
A
--
P
L
L
A
H
-
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
--
G
F
-
V
K
--
T
A
M
Q
E
R
E
I
I
W
E
A
E
L
R
GMT
P
E
A
V
R
A
E
Y
V
-
S
---------
L
T
P
L
G
R
I
E
--
E
P
E
-------
D
V
A
D
V
V
V
F
L
A
S
D
A
A
R
F
M
T
G
Q
-
G
I
N
-
V
T
G
G
V
----------------------------------
129
HHSearch
58.31
25%
-77
- C1 -
3AI3
3
?
A:
[3-260]
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
V
--
A
R
Q
V
D
R
L
H
--------
E
A
A
R
S
-
L
K
E
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
------
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
---
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
------
A
R
-
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
--
W
Y
E
P
I
-
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
--
G
L
-
I
L
--
T
P
D
W
I
K
T
A
K
E
L
T
K
DNGGD
W
K
G
Y
L
Q
S
V
A
D
E
---------
H
A
P
I
K
R
F
A
--
S
P
E
-------
E
L
A
N
F
F
V
F
L
C
S
E
R
A
T
Y
S
V
G
S
A
Y
-
F
-
V
D
G
G
M
L
---------------------------------
5
PsiBlast_PDB
49.33
33%
-67
- C1 -
3OSU
15
FABG_STAAM
A:
[5-199]
-----
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
--
V
A
--
V
N
Y
A
G
S
K
E
K
A
E
-----
A
V
V
E
E
-
I
K
-
A
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
---
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
------
R
Q
-
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
--
P
G
Q
A
N
-
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
--
G
F
I
V
S
DM
T
D
A
L
S
D
E
L
------------------------------------------------------------------------------------------------------------------