@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3748: (2016-02-20 )
MDELHPGYLVGLLVLLVACSAFFSCVETALLNLDRYRLRLQAKQGLRGARRSSWLLLHDDRLRGTLLFGRTLVNVSAAALASWAALRHWGVIGLAVAIPGMTLLLLLFGALLPRRYGALRSERVALPLSLPLLILQRLCWPLLWLLTLLSNALLRLLGVAAAEQDDSGRSRDEEALHPADNPQASEVNRHDMLLGLLDLEKVTVNDLMIPRNEIEGIDLDDELEVIVEQLRTTSHTRLPVYRDDVNQIEGVVHMRQIARLLTQGRLTKENLRQACMEPYFVPESTPLSTQLVNFQKEKRRIGVVVDEYGEVIGIVTLEDILEEIVGDFNDLDSLDNPDIQAQEDGSFVIDGSANLRELNKSLGWQLPCDGPKTLNGLVTEALEQIPDCAVCLRIGPYCLEIQQSAENRVKSVRAWHPRALTPLVESDASV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......--180.......190....---...200.......210..----.....220.-..-....230.......240.......250....-.---..260-....-....270...----...-.280.......290.......300...--------..--------..310.......320.......330.......340-.......350.......360.......370.......380.......390.......400.......410.......420.......430
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDELH
P
G
Y
L
V
G
L
L
V
L
L
V
A
C
S
A
F
F
S
C
V
E
T
A
L
L
N
L
D
R
Y
R
L
R
L
Q
A
K
QGLRGARRS
S
W
L
L
L
HDDRL
R
G
T
L
L
FG
R
T
L
V
N
V
S
A
A
A
L
A
S
W
A
A
L
R
H
WG
V
I
G
L
A
V
A
I
P
G
M
T
L
L
L
L
L
F
G
A
L
L
P
R
R
Y
G
ALRSE
R
V
ALPLS
L
P
L
L
I
L
Q
R
L
C
W
P
L
L
W
L
L
T
L
L
S
N
A
L
L
R
L
L
G
VAAAEQDDSGRSR
D
E
EALHPA--DNPQASEV
N
R
H
D
M
L
L
G
L
---
L
D
L
E
KVTVNDLMIPRNEI----EGIDL
D
D
E
L
-
E
V
-
I
V
E
Q
L
R
TTSHTRLPVYRD
D
V
N
Q
I
E
G
V
V
H
M
R
Q
-
I
---
A
R
L
-
L
-TQGR-L
T
K
E
N
L
R
Q
A
C
----MEP-YFVPESTPL
S
T
Q
L
V
N
F
Q
K
E
KRRI
G
V
V
V
--------DE--------YG
E
V
I
G
I
V
T
L
E
D
I
L
E
E
I
V
GDFNDLDSLDNPDIQAQ-EDG
S
F
V
IDGSA
N
L
R
E
L
N
K
SLGWQLPCDG
P
K
T
L
N
G
L
V
T
E
A
L
E
QIPD
C
A
V
C
L
RIG
P
Y
C
L
E
I
Q
Q
S
A
E
N
R
V
K
S
V
RAWHPRAL
T
P
L
VESDASV
1
PsiBlast_PDB
89.18
54%
-102
- C1 -
3HF7
1
?
A:
[1-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
----
V
G
I
D
I
N
D
D
W
-
K
S
-
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
-
A
---
Y
R
L
-
M
-
T
E
K
K
E
F
T
K
E
I
M
L
R
A
A
----
D
E
I
-
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
---------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.73
28%
-85
* C1 *
4HG0
1
CORC_ECOLI
A:
[56-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
L
E
G
V
---
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
L
D
E
C
L
-
D
V
-
I
I
E
----
S
A
H
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
-
L
LPF
M
R
S
-
D
-
A
E
A
F
-
S
M
D
K
V
L
R
Q
A
V
----
V
-----
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
L
V
M
Q
A
F
G
H
L
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
I
P
-------------
51
Fugue
87.69
53%
-102
- C1 -
3HF7
1
?
A:
[1-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
----
V
G
I
D
I
N
D
D
W
-
K
S
-
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
-
A
---
Y
R
L
-
M
T
E
K
K
E
-
F
T
K
E
I
M
L
R
A
A
----
D
E
I
-
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
---------------------------------------------------------------------------------------------------------
48
HHSearch
83.54
53%
-96
- C1 -
3HF7
1
?
A:
[2-127]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
V
N
D
I
M
V
P
R
N
E
I
----
V
G
I
D
I
N
D
D
W
-
K
S
-
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
-
A
---
Y
R
L
-
M
-
T
E
K
K
----
E
F
T
K
E
I
M
L
R
A
A
D
E
I
-
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
---------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.26
28%
-79
- C1 -
3OCM
7
?
A:
[21-166]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
E
R
N
M
V
S
G
V
---
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
----
S
W
V
N
I
D
D
D
A
-
A
T
-
I
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
R
G
S
L
D
E
V
V
G
I
G
R
A
K
D
L
V
---
A
D
L
-
I
-
T
E
G
R
-
V
R
R
N
R
L
R
--------
D
P
-
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
--------
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
G
E
F
P
D
E
D
E
L
--
P
----------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.07
31%
-93
- C1 -
3LV9
1
?
A:
[18-147]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
----
V
C
I
Y
E
S
D
S
E
-
E
K
-
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
-
L
Y
--
N
Q
K
-
I
-
N
E
N
K
-
I
---
E
L
E
E
I
L
----
R
D
I
-
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
I
-------------------------------------------------------------------------------------------------------
30
HHSearch
71.88
26%
-75
- C1 -
3OI8
4
?
A:
[3-156]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
---
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
----
N
V
L
K
E
N
D
S
I
-
E
R
-
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
-
L
---
L
K
Y
-
M
-
F
N
P
---
E
Q
F
H
L
K
S
I
L
----
R
P
A
-
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
-------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
71.56
29%
-89
- C1 -
3LHH
1
?
A:
[43-167]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
----
V
F
L
D
L
N
L
P
L
-
D
A
-
N
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
N
V
D
D
M
V
G
I
I
S
A
K
Q
L
L
---
S
E
S
-
I
-
A
G
E
R
-
L
E
L
V
D
L
V
K
N
C
--------
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
--------
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
F
------------
F
------------------------------------------------------------------------------------------
34
HHSearch
71.32
31%
-79
- C1 -
3LV9
1
?
A:
[18-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
----
V
C
I
Y
E
S
D
S
E
-
E
K
-
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
-
L
---
Y
N
Q
-
K
-
I
N
E
---
N
K
I
E
L
E
E
I
L
----
R
D
I
-
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
--------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.81
32%
-99
- C1 -
3JTF
4
?
A:
[6-128]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
A
D
I
M
V
P
R
S
R
M
----
D
L
L
D
I
S
Q
P
L
-
P
Q
-
L
L
A
T
I
I
E
T
A
H
S
R
F
P
V
Y
E
D
D
R
D
N
I
I
G
I
L
L
A
K
D
-
L
---
L
R
Y
-
M
-
L
E
P
A
-
L
---
D
I
R
S
L
V
----
R
P
A
-
V
F
I
P
E
V
K
R
L
N
V
L
L
R
E
F
R
A
S
R
N
H
L
A
I
V
I
--------
D
E
---------
G
G
I
S
G
L
V
T
M
E
D
V
L
E
Q
I
V
G
D
I
-------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
69.79
26%
-80
- C1 -
4P1O
2
CNNM2_MOUSE
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
VNNEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
69.60
27%
-80
- C1 -
4IY3
-
CNNM4_HUMAN
B:
[2-146]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
M
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
Q
L
Q
D
C
----
F
M
I
R
S
D
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
D
E
Q
S
N
I
V
D
I
L
Y
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
R
F
Y
----
N
H
P
V
H
F
V
F
H
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
K
V
N
NEG--
D
P
--------
F
Y
E
V
L
G
L
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.57
29%
-85
- C1 -
3OI8
4
?
A:
[6-156]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
V
L
N
L
L
--
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
----
N
V
L
K
E
N
D
S
I
-
E
R
-
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
-
L
---
L
K
Y
-
M
-
F
N
P
E
---
Q
F
H
L
K
S
I
L
----
R
P
A
-
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
-------------------------------------------------------------------------------------------------------------
29
HHSearch
69.51
27%
-87
- C1 -
3LHH
1
?
A:
[43-167]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
----
V
F
L
D
L
N
L
P
L
-
D
A
-
N
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
N
V
D
D
M
V
G
I
I
S
A
K
Q
-
L
---
L
S
E
-
S
-
I
A
G
---
E
R
L
E
L
V
D
L
V
----
K
N
C
-
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
--------
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
F
F
------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
69.47
26%
-84
- C1 -
4P1G
1
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
69.34
26%
-79
- C1 -
4IY2
-
CNNM2_HUMAN
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
69.05
26%
-80
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
68.95
26%
-79
- C1 -
4IY0
4
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
68.13
26%
-77
- C1 -
4IYS
-
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
-
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
-
D
-
P
D
D
C
-
T
P
L
K
T
I
T
K
F
Y
----
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
VNNEGE-
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
----------------------------------------------------------------------------------------------------------
52
Fugue
66.92
26%
-69
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[1-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
N
I
I
Q
G
A
---
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
----
F
M
I
T
G
E
A
I
L
D
F
N
-
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
-
L
---
A
F
V
D
P
-
D
D
C
T
-
P
L
K
T
I
T
K
F
Y
N
----
H
P
L
-
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
--------
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
K
S
E
-------------------------------------------------------------------------------------------------------