@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5208: (2016-03-05 )
MPTNPFISLFGRSPIGPMQQHIAKAHECAAGLLPFFRAVIAEDWAQVEQVQQDMVRLEQEADRLKKHVRMHLPKSLFLPVPRSDLLELLSVQDKVANRAKDIAGLMLGRRMRIPLPLQGQMLAYVQRSVDASAQALRVVNELNELLETGFGGRETSLVESMVEELEAIENDTDRIQVEVRRELFRLESELPPVDVMFLYQIIEWIGDVADRAQRVGNRLEQLLAR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-----.......20-----.-----.....-------..30........40.--.......50........60-.........70....---.--.--.----------.80.-----.-----......-----90........100.-----......110..-------------.....120-----........130---.......-------..-140......---.-150.......160........170....---------...180-----......--.-----190...-...------------.200......-----.210-----------........220....------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTNPF
I
S
LFGR-----SPI
G
P
M
Q
Q
H
-----
I
-----
A
K
A
H
E
-------
C
A
A
G
L
L
P
F
F
R
A
V
I
A
E
--
D
W
A
Q
V
E
Q
V
Q
Q
D
M
V
R
L
E
Q
E
--
A
D
R
L
K
K
H
V
R
M
HL
P
K
S
---L--F--L----------PV
P
R
-----
S
-----
D
L
L
E
L
L
-----
S
V
Q
D
K
V
A
N
R
A
K
D
I
A
-----
G
L
M
LGRRMRIP-------------LPLQ
G
Q
M
------
L
A
Y
V
Q
R
SVD-----
A
S
A
Q
A
L
R
-------
V
V
-
N
E
L
N
E
L
L
ET---G-FGG
R
E
T
S
L
V
E
S
M
-
V
E
E
L
E
A
IENDT
D
R
I
Q
---------
V
E
V
R
R
E
-----
L
F
R
L
ES--E-----LP
P
V
D
V
-
M
F
L
------------
Y
Q
I
I
E
W
I
G
D
V
-----
A
D
R
------------
A
Q
R
V
G
N
R
L
E
Q
-
L
LAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
99.51
52%
-116
- C2 -
2OLT
2
?
A:
[14-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
K
P
L
Q
E
H
-----
M
-----
D
K
V
Y
D
-------
C
A
S
L
L
V
P
F
F
E
A
T
I
T
G
--
N
W
D
D
A
V
Q
I
R
K
Q
I
S
L
A
E
K
Q
--
G
D
S
L
K
R
E
I
R
L
T
L
P
S
G
---
L
--
F
--
M
----------
P
V
E
R
-----
T
-----
D
L
L
E
L
L
-----
T
Q
Q
D
K
I
A
N
K
A
K
D
I
S
-----
G
R
V
I
G
R
Q
L
L
I
P
-------------
Q
A
L
Q
V
P
F
------
I
A
Y
L
Q
R
C
I
D
-----
A
V
G
L
A
Q
Q
-------
V
I
-
N
E
L
D
D
L
L
E
A
---
G
-
F
R
G
R
E
V
D
F
V
A
K
M
-
I
N
E
L
D
I
I
E
E
D
T
D
D
L
Q
---------
I
Q
L
R
R
Q
-----
L
F
A
L
E
S
--
E
-----
L
N
P
V
D
V
-
M
F
L
------------
Y
K
T
I
E
W
V
G
G
L
-----
A
D
L
------------
A
E
R
V
G
S
R
L
E
L
-
M
L
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
98.66
50%
-116
- C2 -
2OLT
2
?
A:
[14-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
K
P
L
Q
E
H
-----
M
-----
D
K
V
Y
D
-------
C
A
S
L
L
V
P
F
F
E
A
T
I
T
G
--
N
W
D
D
A
V
Q
I
R
K
Q
I
S
L
A
E
K
Q
--
G
D
S
L
K
R
E
I
R
L
T
L
P
S
G
---
L
--
F
--
M
----------
P
V
E
R
-----
T
-----
D
L
L
E
L
L
-----
T
Q
Q
D
K
I
A
N
K
A
K
D
I
S
-----
G
R
V
I
G
R
Q
L
L
I
P
-------------
Q
A
L
Q
V
P
F
------
I
A
Y
L
Q
R
C
I
D
-----
A
V
G
L
A
Q
Q
-------
V
I
-
N
E
L
D
D
L
L
E
A
---
G
-
F
R
G
R
E
V
D
F
V
A
K
M
-
I
N
E
L
D
I
I
E
E
D
T
D
D
L
Q
---------
I
Q
L
R
R
Q
-----
L
F
A
L
E
S
--
E
-----
L
N
P
V
D
V
-
M
F
L
------------
Y
K
T
I
E
W
V
G
G
L
-----
A
D
L
------------
A
E
R
V
G
S
R
L
E
L
-
M
L
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.48
50%
-114
- C2 -
2IIU
3
?
A:
[14-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
K
P
L
Q
E
H
-----
M
-----
D
K
V
Y
D
-------
C
A
S
L
L
V
P
F
F
E
A
T
I
T
G
--
N
W
D
D
A
V
Q
I
R
K
Q
I
S
L
A
E
K
Q
--
G
D
S
L
K
R
E
I
R
L
T
---
G
---
L
--
F
--
M
----------
P
V
E
R
-----
T
-----
D
L
L
E
L
L
-----
T
Q
Q
D
K
I
A
N
K
A
K
D
I
S
-----
G
R
V
I
G
R
Q
L
L
I
P
-------------
Q
A
L
Q
V
P
F
------
I
A
Y
L
Q
R
C
I
D
-----
A
V
G
L
A
Q
Q
-------
V
I
-
N
E
L
D
D
L
L
E
-------
R
G
R
E
V
D
F
V
A
K
M
-
I
N
E
L
D
I
I
E
E
D
T
D
D
L
Q
---------
I
Q
L
R
R
Q
-----
L
F
A
L
E
S
--
E
-----
L
N
P
V
D
V
-
M
F
L
------------
Y
K
T
I
E
W
V
G
G
L
-----
A
D
L
------------
A
E
R
V
G
S
R
L
E
L
-
M
L
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
86.17
48%
-101
- C2 -
2IIU
3
?
A:
[14-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
K
P
L
Q
E
H
------
M
----
D
K
V
Y
D
-------
C
A
S
L
L
V
P
F
F
E
A
T
I
T
G
--
N
W
D
D
A
V
Q
I
R
K
Q
I
S
L
A
E
K
Q
--
G
D
S
L
K
R
E
I
R
L
----
T
---
G
--
L
--
F
M---------
P
V
E
R
-----
T
-----
D
L
L
E
L
L
-----
T
Q
Q
D
K
I
A
N
K
A
K
D
I
S
-----
G
R
V
I
G
R
Q
L
L
I
P
-------------
Q
A
L
Q
V
P
F
------
I
A
Y
L
Q
R
C
I
D
-----
A
V
G
L
A
Q
Q
-------
V
I
-
N
E
L
D
D
L
L
E
R
---
G
-
R
E
V
D
F
V
A
----
K
M
I
N
E
L
D
I
I
E
E
D
T
D
D
L
Q
---------
I
Q
L
R
R
Q
-----
L
F
A
L
E
S
--
E
-----
L
N
P
V
D
V
M
F
-
L
------------
Y
K
T
I
E
W
V
G
G
L
-----
A
D
L
------------
A
E
R
V
G
S
R
L
E
L
M
L
A
R
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
55.59
16%
-73
- C2 -
3L39
6
?
A:
[19-227]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
F
T
P
-----
K
E
P
K
F
F
P
L
L
-----
K
-----
Q
L
S
D
V
-------
L
S
A
S
S
V
L
L
V
E
S
M
E
H
D
--
L
P
T
E
R
A
D
Y
Y
K
Q
I
K
D
M
E
R
E
--
G
D
R
L
T
H
L
I
F
D
E
L
S
T
T
---
F
--
I
--
T
----------
P
F
D
R
-----
E
-----
D
I
H
D
L
A
-----
S
C
M
D
D
V
I
D
G
I
N
S
S
A
-----
K
R
I
V
I
Y
N
P
R
P
I
-------------
S
E
S
G
K
E
L
------
S
R
L
I
H
E
E
A
I
-----
N
I
G
K
A
M
D
-------
E
L
-
E
T
F
R
-------------
K
N
P
K
P
L
R
D
Y
-
C
T
Q
L
H
D
I
E
N
Q
A
D
D
V
Y
---------
E
L
F
I
T
K
-----
L
F
E
E
E
K
--
D
-------
C
I
E
L
-
I
K
I
------------
K
E
I
M
H
E
L
E
K
T
-----
T
D
A
------------
A
E
H
V
G
K
I
L
K
N
-
L
I
V
K
Y
S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
55.29
16%
-71
- C2 -
3L39
6
?
A:
[19-225]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
F
T
P
K
E
P
-----
K
F
F
P
L
L
K
Q
L
-----
S
-----
D
V
L
S
A
-------
S
S
V
L
L
V
E
S
M
E
H
D
L
P
T
-----
E
R
A
D
Y
Y
K
Q
I
K
D
M
E
R
E
--
G
D
R
L
T
H
L
I
F
D
E
L
S
T
T
---
F
--
I
--
T
----------
P
F
D
R
-----
E
-----
D
I
H
D
L
A
-----
S
C
M
D
D
V
I
D
G
I
N
S
S
A
-----
K
R
I
V
I
Y
N
P
R
P
I
-------------
S
---
E
S
G
------
K
E
L
S
R
L
I
H
E
-----
E
A
I
N
I
G
K
-------
A
M
-
D
E
L
E
T
F
----------
R
K
N
P
K
P
L
R
D
Y
-
C
T
Q
L
H
D
I
E
N
Q
A
D
D
V
Y
---------
E
L
F
I
T
K
-----
L
F
E
E
E
---------
K
D
C
I
E
L
-
I
K
I
------------
K
E
I
M
H
E
L
E
K
T
-----
T
D
A
------------
A
E
H
V
G
K
I
L
K
N
-
L
I
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
53.94
15%
-67
- C2 -
1SUM
10
PHOU2_THEMA
B:
[21-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
-------
I
E
K
M
F
R
N
S
I
S
S
L
V
E
R
--
N
----
E
S
L
A
R
E
V
I
A
D
E
E
V
--
V
D
Q
M
E
V
E
I
Q
E
K
A
M
E
V
---
L
--
G
LF
S
----------
P
I
G
K
PLLTV
T
-----
A
G
I
R
V
A
-----
E
L
I
E
N
I
A
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C
H
D
I
A
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M
E
E
P
P
-------------
L
K
P
L
E
D
I
------
P
A
M
A
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Q
T
S
E
-----
M
L
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F
A
----------
L
-
R
M
F
A
D
------------
V
N
V
E
----
K
-
S
F
E
V
C
R
M
D
S
K
V
D
D
L
Y
---------
E
K
V
R
E
E
-----
L
L
L
Y
M
M
--
E
SP---
K
Y
V
K
R
A
-
L
L
L
------------
L
E
I
A
G
N
I
E
I
I
-----
A
D
Y
------------
A
T
N
I
V
E
V
S
V
Y
-
M
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
49.11
11%
-67
- C2 -
1SUM
11
PHOU2_THEMA
B:
[2-225]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
L
L
N
-----
E
K
V
E
E
F
K
K
G
-----
V
-----
L
K
A
G
W
-------
F
I
E
K
M
F
R
N
S
I
S
S
L
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E
-----
R
N
E
S
L
A
R
E
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I
A
D
E
E
V
--
V
D
Q
M
E
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E
I
Q
E
K
A
M
E
V
---
L
--
G
--
L
----------
F
S
P
I
-----
G
-----
K
P
L
L
T
V
-----
T
A
G
I
R
V
A
E
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I
E
N
I
A
-----
D
K
C
H
D
I
A
K
N
V
L
-------------
E
L
M
E
E
P
P
------
L
K
P
L
E
D
I
P
A
-----
M
A
N
Q
T
S
E
-------
M
L
-
K
F
A
L
R
M
F
A
D
--------
V
N
V
E
K
S
F
E
V
-
C
R
M
D
S
K
V
D
D
L
Y
E
K
V
R
---------
E
E
L
L
L
Y
-----
M
M
E
--
S
--
P
-----
K
Y
V
K
R
A
-
L
L
L
------------
L
E
I
A
G
N
I
E
I
I
-----
A
D
Y
------------
A
T
N
I
V
E
V
S
V
Y
-
M
V
Q
G
EAYKCYHDELLLFKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
48.24
12%
-77
- C2 -
2I0M
2
PHOU_STRPN
A:
[11-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
Q
S
F
L
G
L
-----
G
-----
Q
---
L
-------
V
L
E
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A
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L
A
L
A
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--
D
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----
E
M
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E
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--
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A
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A
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---
L
A
L--------------
P
Q
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-----
D
L
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C
-----
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-----
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-------------
A
--
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E
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L
------
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Q
M
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-----
M
L
A
D
L
----------
L
-
V
A
F
P
L
------------
H
Q
A
S
----
K
-
A
I
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A
Q
K
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E
Q
I
D
Q
Y
Y
---------
Y
A
L
S
K
E
-----
I
I
G
L
M
K
--
D
QE----
S
I
P
N
G
-
T
Q
Y
------------
L
Y
I
I
G
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E
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F
-----
A
D
Y
------------
I
A
N
I
C
E
R
L
V
Y
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.53
23%
-59
- C2 -
3L39
5
?
A:
[68-225]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
R
E
--
G
D
R
L
T
H
L
I
F
D
E
L
S
T
T
---
F
--
I
--
T
----------
P
F
D
R
-----
E
-----
D
I
H
D
L
A
-----
S
C
M
D
D
V
I
D
G
I
N
S
S
A
-----
K
R
I
V
I
Y
N
P
R
-
P
-------------
I
S
E
S
G
K
E
------
L
S
R
L
----------
I
H
E
E
A
I
N
-------
I
G
-
K
A
M
D
E
-
L
E
T
------
F
R
K
N
P
K
P
L
R
D
Y
-
C
T
Q
L
H
D
I
E
N
Q
A
D
D
V
Y
---------
E
L
F
I
T
K
-----
L
F
--
E
E
--
E
-----
K
D
C
I
E
L
-
I
K
I
------------
K
E
I
M
H
E
L
E
K
T
-----
T
D
A
------------
A
E
H
V
G
K
I
L
K
N
-
L
I
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
40.78
16%
-75
- C2 -
4WD8
4
?
A:
[25-292]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SK
I
I
F
R
L
L
L
N
V
L
M
S
I
I
A
I
-----
I
S
Y
Q
W
Y
E
Q
L
G
I
H
L
T
V
-----
A
P
F
S
L
-------
L
G
I
A
I
A
I
F
L
G
F
R
N
S
A
--
S
Y
S
R
F
V
E
A
R
N
L
W
G
T
V
L
I
A
--
E
R
T
L
V
R
Q
L
R
N
I
L
P
A
E
---------
H
----------
D
A
H
R
-----
R
-----
I
V
S
Y
L
V
-----
A
F
S
W
S
L
K
H
Q
L
R
K
T
D
-----
P
T
A
D
L
R
R
L
------------------
L
P
E
E
R
------
V
T
E
I
L
A
S
S
M
-----
P
T
N
R
I
L
L
-------
L
A
G
N
E
I
G
Q
L
R
E
A
---
G
K
L
S
D
I
T
Y
G
L
M
D
N
K
-
L
D
E
L
A
H
V
L
G
G
C
E
R
L
A
T
T
PVP
F
A
Y
T
L
I
L
Q
R
T
-----
V
Y
L
F
C
T
--
L
-----
L
P
F
A
L
V
-
G
D
L
HYM
T
P
F
V
S
V
F
I
S
Y
T
F
L
S
W
D
S
L
A
-----
E
E
L
E
D
PFGTAANDLP
L
N
A
M
C
N
T
I
E
R
-
N
L
L
D
M
T
GQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
37.22
13%
-50
- C2 -
2OLT
2
?
A:
[15-109]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
I
K
P
L
------
Q
E
H
M
D
K
V
Y
D
-----
C
A
S
L
L
V
P
-------
F
F
-
E
A
T
I
T
------------
G
N
W
D
D
A
V
Q
I
-
R
K
Q
I
S
L
A
E
K
Q
G
D
S
L
K
---------
R
E
I
R
L
T
-----
L
P
S
G
L
---------
F
M
P
V
E
R
-
T
D
L
------------
L
E
L
L
T
Q
Q
D
K
I
-----
A
N
K
------------
A
K
D
I
S
G
R
V
I
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
36.51
13%
-67
- C2 -
4O5J
3
?
A:
[27-400]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKN
L
N
E
K
Y
E
Q
L
S
Q
Y
L
N
Q
V
A
S
L
K
Q
S
I
Q
N
A
N
N
I
E
L
V
N
S
S
L
N
Y
L
K
S
F
T
N
N
N
Y
NSTTQS
P
I
F
N
A
V
Q
A
V
I
T
S
V
L
G
F
W
S
L
Y
A
G
N
Y
F
T
F
F
V
G
-------------
K
K
-----
V
-----
D
S
G
Q
P
-------
A
S
V
Q
G
N
P
P
F
K
T
I
I
E
N
CS
G
I
E
N
C
A
M
D
Q
T
T
Y
D
K
M
K
K
L
--
A
E
D
L
Q
A
A
Q
T
N
S
A
T
K
G
---
N
--
N
--
L
CALSGCAATS
N
P
P
N
-----
S
-----
T
V
S
N
A
L
-----
N
L
A
Q
Q
L
M
D
L
I
A
N
T
K
-----
T
A
M
M
W
K
N
I
V
I
S
GVSNTSGAIT
S
T
N
Y
P
T
Q
Y
A
V
------
F
N
N
I
K
A
M
I
P
-----
I
L
Q
Q
A
V
T
-------
L
S
-
Q
S
N
H
T
L
S
A
S
LQA
Q
-
A
T
G
S
Q
T
N
--
P
K
F
-
A
K
D
I
Y
T
F
A
Q
N
Q
K
Q
V
----------
I
S
Y
A
Q
D
-----
I
F
N
L
F
N
--
S
-----
I
P
A
E
Q
Y
-
K
Y
L
------------
E
K
A
Y
L
K
I
P
N
A
-----
G
S
T
------------
P
T
N
P
Y
R
Q
V
V
N
-
L
N
Q
E
V
Q
T
I
K
N
N
V
S
Y
Y
G
N
R
V
D
A
A
L
S
V
A
R
D
V
Y
N
L
K
S
N
Q
A
E
I
V
T
A
Y
N
D
A
K
T
L
S
E
E
I
S
K
LPH------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
31.35
20%
-34
- C2 -
1SUM
6
PHOU2_THEMA
B:
[12-106]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
K
G
V
------
L
K
A
G
W
F
I
E
K
-----
M
F
R
N
S
----------
I
-
S
S
L
V
E
------------
R
N
----
E
S
L
-
A
R
E
V
I
A
D
E
E
V
V
D
Q
M
E
---------
V
E
I
Q
E
K
-----
A
M
E
V
L
G
--
L
FSPIG
K
P
L
L
T
V
-
T
A
G
------------
I
R
V
A
E
L
I
E
N
I
-----
A
D
K
------------
C
H
D
I
A
K
N
V
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
30.58
14%
-13
- C2 -
1T72
-
PHOU_AQUAE
A:
[27-212]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
E
A
I
D
K
A
T
E
A
L
N
K
Q
--
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
--
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
---
I
--
A
--
L
YQ--------
P
E
A
G
D
L
R
M
I
M
-----
G
I
Y
K
I
V
-----
S
D
L
E
R
M
G
D
E
A
E
N
I
A
-----
E
R
A
I
L
L
A
E
E
P
P
-------------
L
K
P
Y
V
N
I
------
N
F
M
S
E
I
V
K
E
-----
M
V
N
D
S
----------
V
-
I
S
F
I
Q
------------
Q
D
----
T
L
L
-
A
K
K
V
I
E
K
D
D
T
V
D
E
L
Y
---------
H
Q
L
E
R
E
-----
L
M
T
Y
V
L
--
E
DP---
R
N
I
K
R
A
-
M
H
L
------------
S
F
V
A
R
H
Y
E
R
I
-----
A
D
H
------------
A
E
N
V
A
E
A
A
I
Y
-
L
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
30.46
12%
-67
- C1 -
3QJ4
3
RNLS_HUMAN
A:
[1-341]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
A
Q
V
L
I
V
G
AG
M
T
G
S
L
C
A
A
L
L
R
R
QTGP
L
Y
L
A
V
W
D
KADDSGGRM
T
T
A
C
S
PHNPQCTADLGAQ
Y
I
T
C
T
PHYAK
K
H
Q
R
F
Y
D
E
L
L
A
Y
-----
G
V
L
R
P
L
S
S
P
-----
I
E
GMVM
G
D
C
N
F
-------
V
A
P
Q
G
I
S
S
I
I
K
H
Y
L
K
--
E
S
G
A
E
V
Y
F
R
H
R
V
T
Q
I
N
L
R
--
D
D
K
W
E
V
S
K
Q
T
G
S
P
E
Q
F
D
L
I
--
V
--
L
----------
T
M
P
V
-----
P
-----
E
I
L
Q
L
Q
G
D
I
T
T
L
I
S
E
C
Q
R
Q
Q
L
E
A
V
S
Y
S
S
R
Y
A
L
G
L
F
Y
E
A
G
T
D
-------------
V
P
W
A
G
Q
Y
I
TSNPC
I
R
F
V
S
I
D
N
K
K
R
NIE
S
S
I
G
P
S
L
-------
V
I
-
H
T
T
V
P
F
G
V
T
---
Y
-
L
E
H
S
I
E
D
V
Q
E
L
V
-
F
Q
Q
L
E
N
I
L
P
G
L
P
Q
P
I
---------
A
T
K
C
Q
K
WRHSQ
V
T
N
A
A
A
--
N
-----
C
P
G
Q
M
T
-
L
H
H
------------
K
P
F
L
A
C
G
G
D
G
FTQSN
F
D
G
------------
C
I
T
S
A
L
C
V
L
E
-
A
L
K
N
Y-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
29.57
15%
-33
- C2 -
1XWM
-
?
A:
[40-207]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
A
M
A
V
I
D
G
D
G
S
--
I
D
A
L
E
E
E
V
N
D
F
A
L
W
L
---
I
--
A
--
A
QQ--------
P
V
A
T
-----
D
L
R
R
I
V
A
A
I
K
I
A
-----
S
D
I
E
R
I
A
D
F
A
V
N
I
A
-----
K
A
C
I
R
I
G
G
Q
P
F
-------------
V
M
D
I
G
P
L
------
V
L
M
Y
R
L
A
T
D
-----
M
V
S
T
A
----------
I
-
A
A
Y
D
R
------------
E
D
----
A
S
L
-
A
A
Q
I
A
D
M
D
H
R
V
D
E
Q
Y
---------
G
E
M
M
A
S
-----
L
L
A
V
A
K
TD
A
-----
A
T
L
A
Q
M
-
N
V
L
------------
A
L
V
A
R
Y
I
E
R
T
-----
A
D
H
------------
A
T
N
I
A
E
H
L
V
Y
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
28.15
13%
-46
- C2 -
3L39
3
?
A:
[28-119]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
P
L
L
------
K
Q
L
S
D
V
L
S
A
-----
S
S
V
L
L
V
E
-------
S
M
-
E
H
D
---------------
L
P
T
E
R
A
D
Y
-
Y
K
Q
I
K
D
M
E
R
E
G
D
R
L
T
---------
H
L
I
F
D
E
-----
L
S
T
T
F
---------
I
T
P
F
D
R
-
E
D
I
------------
H
D
L
A
S
C
M
D
D
V
-----
I
D
G
------------
I
N
S
S
A
K
R
I
V
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
27.68
16%
-34
- C2 -
4ZUZ
-
?
A:
[7-863]
D
V
I
K
F
K
EPERCDY
L
Y
V
D
ENN
K
V
H
I
L
L
P
IVGGDE
I
G
L
D
N
TC
Q
T
A
V
E
L
I
T
F
F
YGSAHSGVTKYS
A
E
H
Q
L
S
E
Y
K
R
Q
L
E
E
D
I
K
A
I
N
S
Q
KKISPHAY
D
D
L
L
K
E
K
I
E
R
L
Q
Q
I
E
K
Y
I
E
L
I
Q
V
L
K
K
QYDEQN
D
I
R
Q
L
R
TGGIPQLP
S
G
V
K
E
I
I
K
S
SEN
A
F
A
V
R
L
S
P
YDNDKFTRFDDPL
F
N
V
K
R
N
ISKYDTPSRQ
A
P
I
P
I
YEG
L
G
Y
R
L
R
S
T
L
FPEDK
T
P
T
P
I
N
K
K
S
L
R
D
K
V
K
S
T
V
L
S
HYKDEDRIDGEK
K
D
E
K
L
N
E
L
I
T
N
L
Q
N
E
L
V
K
E
L
V
K
S
DPQYSKLSLSKDPRG
K
E
I
N
YDYLVNSLMLVDNDSE
I
G
D
W
I
D
T
I
L
D
A
T
VDSTVWAVQASSPFYQGAKEISS
D
R
D
A
D
K
I
S
I
R
V
Q
Y
L
L
A
E
A
N
I
Y
C
K
T
N
KLSDAN
F
G
E
F
F
D
KE
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
GAD
I
E
P
I
I
Y
D
Y
I
N
S
NHAELGLKSPLT
G
K
Q
Q
Q
E
I
T
D
K
F
T
K
H
Y
N
T
I
K
ESPHFD
E
F
F
V
A
D
PDKKGN
I
F
S
H
QG
R
I
S
C
H
F
L
D
F
F
T
R
Q
T
KGK
H
P
L
G
D
L
A
S
H
-----
Q
-----
E
A
L
Q
E
-------
G
T
S
N
R
L
H
H
K
N
E
V
V
A
Q
--
G
Y
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
NK
P
K
E
L
L
D
Y
L
V
A
T
S
P
T
G
---------------------
V
P
N
-----
Y
-----
S
M
L
S
K
E
-----
T
Q
N
Y
I
A
Y
N
R
N
W
P
A
I
-----
Q
K
E
L
E
K
A
T
S
I
P
-------------
E
S
Q
K
Q
D
L
------
S
R
L
L
S
R
D
N
L
-----
Q
H
---------------
D
N
L
S
A
I
T
W
S
---
K
-
Y
S
S
K
P
L
-
L
D
V
E
L
-
N
K
I
A
E
G
L
E
L
-
T
A
K
I
Y
---------
N
E
K
R
G
R
-----
E
W
W
F
A
G
--
S
-----
R
N
E
A
R
K
-
T
Q
C
------------
E
E
L
Q
R
V
S
K
E
I
-----
N
T
L
------------
L
Q
S
E
S
L
T
K
S
Q
-
V
L
E
K
V
L
N
S
I
E
T
L
D
K
I
D
R
D
I
S
A
E
SNWFQS
T
L
Q
K
E
V
R
L
F
R
D
Q
L
K
D
I
C
QLDK
Y
Y
F
K
S
TKLD
E
I
I
S
L
E
M
E
E
Q
F
Q
K
IQD
P
A
V
Q
Q
I
V
R
D
LPSHCHN
D
E
A
I
E
F
F
K
T
L
N
P
E
E
A
A
K
V
A
S
Y
L
S
L
E
Y
R
E
I
N
KSTDK
K
T
L
L
E
Q
D
I
P
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
K
E
E
KAID
E
Q
V
H
E
K
L
S
Q
L
ADKIAPEHFT
R
N
N
I
I
K
W
S
T
27
Fugue
27.52
18%
-29
- C2 -
4RKN
14
MCCA_WOLSU
A:
[43-702]
-------------------------------------MQMT
K
E
A
R
E
I
I
A
HPKGTKESRGVIS
L
Q
D
Y
I
V
E
E
Q
A
M
Y
D
W
L
F
K
NHPIFTKYGGKTV
G
K
L
V
V
K
D
RGEEWIEEGR
G
N
D
F
S
K
A
SKRSGGEGFSSMMYRVARNSTLQYPNKFIG
P
E
K
C
G
E
CH
P
A
Q
Y
E
T
W
S
R
SRHATTIRFPGEHPEVNNKLNDPVFDKDTASILPQGITPDVVYCTVGHIR
T
K
F
G
F
F
D
AWLLRGT
Y
H
V
E
GGLLKNGT
G
Q
I
V
A
G
GNQWQRTWALNLS
P
E
V
A
K
K
I
K
K
W
V
PDFPVTLEEYGDNGGYVRG
L
A
S
Y
AAKYKKSMSFQASTSYCEVCH
P
W
K
F
DFKN
E
S
E
F
Y
A
A
LGN
A
K
E
L
Q
K
H
TISKGVS
C
E
E
C
H
GAGGHLEGGS
G
L
L
I
S
NCERCHQR
F
S
Y
S
P
D
L
M
R
N
N
PLNAGKPDLALSSKFKSM
G
P
G
C
GS
E
G
S
Q
T
Y
FT
A
H
Y
E
K
GMRCATCHDPHDVTGN
V
T
G
E
KGIKGVSYNSEQGYLSS
L
Y
S
K
P
--
K
L
K
K
E
-----
C
T
D
C
H
K
E
Q
A
-----
Y
-----
I
Q
S
K
A
DTHSKNS
C
A
S
C
H
M
P
F
M
M
S
C
--
E
--
N
F
Y
A
I
Q
F
---------
Q
D
--
Q
A
G
F
D
T
Q
R
R
A
H
I
W
K
----
I
--
D
--
V
----------
D
P
A
R
-----
K
-----
S
L
V
A
G
S
-----
T
S
K
D
P
-----
R
D
G
K
-----
D
W
H
F
E
R
N
E
E
G
R
-------------
N
F
V
D
--
L
------
M
W
A
C
A
R
T
T
W
-----
A
D
K
D
Q
A
E
A
KGCHSP
V
V
-
S
E
L
K
E
T
L
H
F
---
K
----
D
Q
K
Q
V
Y
N
E
V
-
M
G
W
Q
T
P
V
K
D
K
F
T
Q
V
K
---------
V
G
I
Q
G
L
-----
Y
S
L
L
E
V
--
K
K----
L
A
P
S
D
K
-
T
R
V
------------
Y
E
L
I
E
K
A
Q
D
T
-----
V
D
L
------------
I
E
K
D
G
S
W
G
M
H
-
G
F
K
Y
T
K
Q
R
L
D
A
A
V
E
Y
I
N
E
A
Q
R
I
M
K
K
S
L-------------------------------------------------------------------------------------------------------------------------------------------------------------