@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : PF00018_LCK_HU: (2014-08-10 )
GCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP

Atome Classification :

(58 SA) .........10........20........30........40........50........60........70........80........90.--.-......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220....-...-230---.......240......-.250.......260.-------.------.--------....270.......--280-..--.......290..-.....300.....-..310.......320.......330-------------.--.......340.......350.......360.......370-----.......380.......-390-.--..-.....400.......410.......420.......430.......440.....-..450.......460.......470.......480.......490.......500......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) GCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQ--S-GEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQ-KPQ-KPW---WEDEWEVPRETLKLVE-RLGAGQFGEVWMGYY-------N------G--------HTKVAVKSLKQGSM--S---PD--AFLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLKTPS--------------G--IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-----DTLSCKIADFGLARLIE-DN--E--YT-AREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
27 PsiBlast_CBE 97.0772%-114 - C2 -3VS6 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
35 PsiBlast_CBE 96.8572%-117 - C2 -3VS2 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTL---GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
32 PsiBlast_CBE 96.7472%-115 - C2 -3VS3 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT-----FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVIE----------------KFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
34 PsiBlast_CBE 96.5972%-113 - C2 -3VS2 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
46 PsiBlast_CBE 96.5872%-114 - C2 -2C0O HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
48 PsiBlast_CBE 96.5672%-110 - C2 -2C0I HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
31 PsiBlast_CBE 96.5572%-114 - C2 -3VS4 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR------FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVIE-----------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
50 PsiBlast_CBE 96.5072%-108 - C2 -1QCF HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVIE-DN--E--YT-AREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
33 PsiBlast_CBE 96.5072%-111 - C2 -3VS3 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
47 PsiBlast_CBE 96.4872%-109 - C2 -2C0O HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
41 PsiBlast_CBE 96.4272%-111 - C2 -3VRZ HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
44 PsiBlast_CBE 96.2272%-112 - C2 -2C0T HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
42 PsiBlast_CBE 96.1672%-115 - C2 -3VRY HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
36 PsiBlast_CBE 96.0972%-115 - C2 -3VS1 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
38 PsiBlast_CBE 96.0172%-112 - C2 -3VS0 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
45 PsiBlast_CBE 95.9872%-112 - C2 -2C0T HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR------FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
26 PsiBlast_CBE 95.9872%-113 - C2 -3VS6 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
29 PsiBlast_CBE 95.9772%-116 - C2 -3VS5 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
30 PsiBlast_CBE 95.8972%-112 - C2 -3VS4 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
49 PsiBlast_CBE 95.7572%-113 - C2 -2C0I HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
40 PsiBlast_CBE 95.6272%-116 - C2 -3VRZ HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
24 PsiBlast_CBE 95.6072%-116 - C2 -4LUD ? A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVAR---LETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLD--GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKP-----S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-----LERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
28 PsiBlast_CBE 95.5972%-118 - C2 -3VS5 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR------FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
39 PsiBlast_CBE 95.5272%-114 - C2 -3VS0 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR-----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
25 PsiBlast_CBE 95.3772%-110 - C2 -3VS7 HCK_HUMAN B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT-----FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLAR---------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
21 PsiBlast_CBE 95.3572%-116 - C2 -4LUE ? B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKP---------------LAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINF---TIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
43 PsiBlast_CBE 95.2572%-112 - C2 -3VRY HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR------FYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI------------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
37 PsiBlast_CBE 95.2172%-109 - C2 -3VS1 HCK_HUMAN A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIR---------SPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGSM--S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
22 PsiBlast_CBE 94.5972%-112 - C2 -4LUE ? A:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPGS-------------LAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
23 PsiBlast_CBE 92.9972%-112 - C2 -4LUD ? B:[10-447] ---------------------------------------------------------------IVVALYDYEAIHHEDLSFQKGDQMVVLEE--S-GEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSET---SYSLSVRDYDPRQGDTVKHYKI-----------------TLQELVDHYKKGNDGLCQKLSVPCMSS-KPQ-KPW---EKDAWEIPRESLKLEK-KLGAGQFGEVWMATY-------N------K--------HTKVAVKTMKPG----S---VE--AFLAEANVMKTL-QHDKLVKLHAVVT-KEPIYIITEFMAKGSLLDFLKSDE--------------G--SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-----ASLVCKIADFGLARVI-------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE-VIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ-----
5 PsiBlast_PDB 91.2160%-111 - C2 -1Y57 SRC_HUMAN A:[6-448] -----------------------------------------------------------------VALYDYESRTETDLSFKKGERLQIVNN--TEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTS-KPQTQGL---AKDAWEIPRESLRLEV-KLGQGCFGEVWMGTW-------N------G--------TTRVAIKTLKPGTM--S---PE--AFLQEAQVMKKL-RHEKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLKGET--------------G--KYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG-----ENLVCKVADFGLARLIE-DN--E--YT-ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-VLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP--
74 HHSearch 84.0744%-104 - C2 -1OPK ABL1_MOUSE A:[44-480] --------------------------------------------------------------NLFVALYDFVASGDNTLSITKGEKLRVLGYNHN-GEWCEAQT--KNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSG--INGSFLVRESESSPGQRSISLRY-----EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT-IYGVSPNYDKWEMERTDITMKH-KLGGGQYGEVYEGVW-------K------KY-------SLTVAVKTLKEDTM--E---VE--EFLKEAAVMKEI-KHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN--------------R--QEVSAVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVG-----ENHLVKVADFGLSRLMT-GD--T--YT-AHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES--------
9 PsiBlast_PDB 75.08100%-131 - C2 -2OF4 LCK_HUMAN A:[1-271] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPW---WEDEWEVPRETLKLVE-RLGAGQFGEVWMGYY-------N------G--------HTKVAVKSLKQGSM--S---PD--AFLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLKTPS--------------G--IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-----DTLSCKIADFGLARLIE-DN--E--YT-AREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT--------
8 PsiBlast_PDB 74.80100%-131 - C2 -2OF2 LCK_HUMAN A:[1-271] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPW---WEDEWEVPRETLKLVE-RLGAGQFGEVWMGYY-------N------G--------HTKVAVKSLKQGSM--S---PD--AFLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLKTPS--------------G--IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-----DTLSCKIADFGLARLIE-DN--E--YT-AREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT--------
2 PsiBlast_PDB 74.20100%-132 - C2 -3BYU LCK_HUMAN A:[7-277] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPW---WEDEWEVPRETLKLVE-RLGAGQFGEVWMGYY-------N------G--------HTKVAVKSLKQGSM--S---PD--AFLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLKTPS--------------G--IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-----DTLSCKIADFGL---------------------KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT--------
4 PsiBlast_PDB 74.15100%-136 - C2 -3B2W LCK_HUMAN A:[13-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WEVPRETLKLVE-RLGAGQFGEVWMGYY-------N------G--------HTKVAVKSLKQGSM--S---PD--AFLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLKTPS--------------G--IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-----DTLSCKIADFGLARLIE-DN--E--YT-A--GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYQLMRL