Atome 2 Filter

@TOME V2.3
(Nov 2016)

Ref. - - Doc.

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3D Common Core:

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Modeller Result :

Complexes Modeling

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Values color: [ Good | Correct | Middling | Bad ]

Sequence color : MutatedHelixStrandConserved

Query sequence : PF00069_CDK1_M: (2014-08-15 )
MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM

Atome Classification :

	(24 SA)									.........10........20...--.....30........40........50........60........70----.------.------.------......80........90...----.-....100.......110.......120.......130....----...-140.......150.....----..160.......170.......180.......190.......-----------200......-------.----210.......220.......230-..--.--......-240...-..-----..250.----.-......260.......270.......280.......290.....
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		MEDYIKIEKIGEGTYGVVYKGRHR--VTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVL-----M------Q------D------SRLYLIFEFLSMDLKKYLDSI----P-PGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLI----DDK-GTIKLADFGLARAFGIPI----RVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT-----------KKPLFHGDS-------E----IDQLFRIFRALGTPNNEVWPE---VE--S--LQDYKN-TFPKWK-PG-----SLAS-H----V-KNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM
19	PsiBlast_PDB	98.28	64%	-111	- C1 -	3QQL		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
15	PsiBlast_PDB	97.76	64%	-111	- C1 -	3QQF		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
16	PsiBlast_PDB	96.43	64%	-104	- C1 -	3QQG		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
10	PsiBlast_PDB	96.33	64%	-106	- C1 -	3PXY		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
7	PsiBlast_PDB	96.21	64%	-107	- C1 -	3PXF		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
17	PsiBlast_PDB	96.09	64%	-107	- C1 -	3QQH		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
20	PsiBlast_PDB	96.06	64%	-111	- C1 -	3QRT		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
18	PsiBlast_PDB	95.88	64%	-103	- C1 -	3QQJ		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
11	PsiBlast_PDB	95.21	64%	-107	- C1 -	3PXZ		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
14	PsiBlast_PDB	95.16	64%	-106	- C1 -	3QL8		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
12	PsiBlast_PDB	95.07	64%	-104	- C1 -	3PY0		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
8	PsiBlast_PDB	94.92	64%	-100	- C1 -	3PXQ		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
13	PsiBlast_PDB	93.40	64%	-97	- C1 -	3PY1		CDK2_HUMAN	A:[9-304]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-LTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL
45	HHSearch	89.53	60%	-110	- C1 -	3NIZ		?	A:[20-310]	MEKYQKLEKVGEGTYGVVYKAKD---SQGRIVALKRIR------GIPSTAIREISLLKELHHPNIVSLIDVI-----H------S------E------RCLTLVFEFMEKDLKKVLDEN----K---TGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLI----NSD-GALKLADFGLARAFGIPV----R---HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMIT-----------GKPLFPGVT-------D----DDQLPKIFSILGTPNPREWPQ---VQ--E--LPLWKQRTFQVFE-KK-----PWSS-I----I-PGFCQEGIDLLSNMLCFDPNKRISARDAMNHPYFKDLDPQ----
37	HHSearch	85.94	58%	-105	- C1 -	4AU8		CDK5_HUMAN	A:[6-293]	-QKYEKLEKIGEGTYGTVFKAKNR--ETHEIVALKRV---------PSSALREICLLKELKHKNIVRLHDVL-----H---------------------KLTLVFEFCDQDLKKYFDSC----N---GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI----NRN-GELKLADFGLARAFGIPV----R--SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANA----------GRPLFPGND-------V----DDQLKRIFRLLGTPTEEQWPS---MT--K--LPDYKP--YPMYPATT-----SLVN-V----V-PKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-------
50	HHSearch	74.35	40%	-107	- C1 -	4BGQ		CDKL5_HUMAN	A:[11-301]	MNKFEILGVVGEGAYGVVLKCRHK--ETHEIVAIKKFK-------VKETTLRELKMLRTLKQENIVELKEAF-----R------R------R------GKLYLVFEYVEKNMLELLEEM----P---NGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLI----SHN-DVLKLCDFGFARNLSE--------------TRWYRSPELLLGA-PYGKSVDMWSVGCILGELSD-----------GQPLFPGES-------E----IDQLFTIQKVLGPLPSEQMKL---FY--S--NPRFHGLRFPAVNHPQ-----SLERRY----L-GILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ-------
52	HHSearch	73.83	37%	-102	- C1 -	2B9H		FUS3_YEAST	A:[11-313]	-SDFQLKSLLGEGAYGVVCSATHK--PTGEIVAIKKIEPFD-KPLFALRTLREIKILKHFKHENIITIFNIQRPDSFE------N------F------NEVYIIQELMQTDLHRVIST---------QMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLI----NSN-CDLKVCDFGLARIID----------VEFVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFL-----------RRPIFPGRD-------Y----RHQLLLIFGIIGTPHSDNDLRCIESP--R--AREYIK-SLPMYP-AA-----PLEK-M----F-PRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYH------
33	HHSearch	71.40	44%	-97	- C1 -	1UA2		CDK7_HUMAN	A:[13-299]	----EKLDFLGEGQFATVYKARDK--NTNQIVAIKKI---------NRTALREIKLLQELSHPNIIGLLDAF-----G------H------K------SNISLVFDFMETDLEVIIKDN-------SLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSPN----RAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLL-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPD---MC--S--LPDYV--TFKSFP-GI-----PLHH-I----F-SAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRP------
41	HHSearch	70.21	36%	-98	- C1 -	4IC7		MK07_HUMAN	A:[55-353]	-DEYEIIETIGNGAYGVVSSARRR--LTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDIL-----RPTVPYGE------F------KSVYVVLDLMESDLHQIIHS--------SQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLV----NEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA-----------RRQLFPGKN-------Y----VHQLQLIMMVLGTPSPAVIQA---VGAER--VRAYIQ-SLPPRQ-PV-----PWET-V----Y-PGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYH------
40	HHSearch	69.79	38%	-95	- C1 -	3N9X		?	A:[26-370]	-DNYIIKHLIGRGSYGYVYLAYDK--NTEKNVAIKKVNRMFEDLIDCKRILREITILNRLKSDYIIRLYDLI-----I------P------DDLLKF-DELYIVLEIADSDLKKLFKTP--------IFLTEEHIKTILYNLLLGENFIHESGIIHRDLKPANCLL----NQD-CSVKVCDFGLARTI-------------HVVTRWYRAPELILLQENYTKSIDIWSTGCIFAELLNMLQSHINDPTNRFPLFPGSSCFPHEKSN----RDQLNIIFNIIGTPTEDDLKN---IN--KPEVIKYIK-LFPHRK-PI-----NLKQ-K----Y-PSISDDGINLLESMLKFNPNKRITIDQALDHPYLKDVRK-----
49	HHSearch	68.50	41%	-103	- C1 -	4F6U		CDK8_HUMAN	A:[27-340]	-------CKVGRGTYGHVYKAKRKDGKDDKDYALKQIE----GTGISMSACREIALLRELKHPNVISLQKVF-----LSH----A------D------RKVWLLFDYAEHDLWHIIKFHRASK----VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPER-GRVKIADMGF------------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQ-------ENPYHHDQLDRIFNVMGFPADKDWED---IK--K--MPEHST-LMKDFR-RNTYTNCSLIK-YMEKHK-VKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLED-------
54	HHSearch	67.61	32%	-109	- C1 -	1J1B		GSK3B_HUMAN	A:[55-345]	--SYTDTKVIGNGSFGVVYQAKLC--DSGELVAIKKVLQDKR------FKNRELQIMRKLDHCNIVRLRYFF-----Y------SSGEKKDE------VYLNLVLDYVPETVYRVARHY----SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL----DPDTAVLKLCDFGSAKQLVRGE----P-NVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------G----VDQLVEIIKVLGTPTREQIRE---MN------PNYTEFKFPQIK-AH-----PWTK-V----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRD-----
48	HHSearch	64.66	36%	-102	- C1 -	2FST		MK14_HUMAN	X:[29-319]	-ERYQNLSPVG----GSVCAAFDT--KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVF-----T------P------ARSLEEFNDVYLVTHLMGADLN--------------QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAV----NED-CELKILD----------------------ATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLT-----------GRTLFPGTD-------H----IDQLKLILRLVGTPGAELLKK---IS--SESARNYIQ-SLTQMP-KM-----NFAN-V----F-IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYH------
32	HHSearch	49.00	65%	18	- C1 -	4EK4		CDK2_HUMAN	A:[4-296]	MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI---------PSTAIREISLLKELNHPNIVKLLDVI-----H------T------E------NKLYLVFEFLHQDLKKFMDAS----A-L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVPV----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPG---VT--S--MPDYKP-SFPKWA-RQ-----DFSK-V----V-PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPH-