@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00069_MYLK_CHICK: (2014-08-18 )
MGDVKLVTSTRVSKTSLTLSPSVPAEAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPVEHRPSIWGESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNMFEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQGPDKTDTHAQPLCMPPKPTTLATKAIENSDFKQATSNGIAKELKSTSTELMVETKDRLSAKKETFYTSREAKDGKQGQNQEANAVPLQESRGTKGPQVLQKTSSTITLQAVKAQPEPKAEPQTTFIRQAEDRKRTVQPLMTTTTQENPSLTGQVSPRSRETENRAGVRKSVKEEKREPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQYAHSTFEAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSLMLRESSASRAEMLRDGRESASSGERRDGGNYGALTFGRTSGFKKSSSETRAAEEEQEDVRGVLKRRVETREHTEESLRQQEAEQLDFRDILGKKVSTKSFSEEDLKEIPAEQMDFRANLQRQVKPKTLSEEERKVHAPQQVDFRSVLAKKGTPKTPLPEKVPPPKPAVTDFRSVLGAKKKPPAENGSASTPAPNARAGSEAQNATPNSEAPAPKPVVKKEEKNDRKCEHGCAVVDGGIIGKKAENKPAASKPTPPPSKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTIEKVMPEDGGEYKCIAENAAGKAECACKVLVEDTSSTKAAKPAEKKTKKPKTTLPPVLSTESSEATVKKKPAPKTPPKAATPPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLTISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDLQADREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKEEEAELSDDEGKETEVNYRTVTINTEQKVSDVYNIEERLGSGKFGQVFRLVEKKTGKVWAGKFFKAYSAKEKENIRDEISIMNCLHHPKLVQCVDAFEEKANIVMVLEMVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTSIKLIDFGLARRLESAGSLKVLFGTPEFVAPEVINYEPIGYETDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKSRLNCTQCLQHPWLQKDTKNMEAKKLSKDRMKKYMARRKWQKTGHAVRAIGRLSSMAMISGMSGRKASGSSPTSPINADKVENEDAFLEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMGKEGEGEGEGEEDEEEEEE
Atome Classification :
(6 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450...--...1460......1470......1480.--.....1490---.------........1500......1510......1520......1530......1540......1550......1560......1570......1580...--..--.1590......1600......1610--.......1620......1630......1640......1650......1660......1670......1680......1690......1700......-1710--.......1720--....---...1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MG
D
V
K
L
V
T
STRV
S
K
T
S
L
T
LSPSVPAEAP
A
F
TLPPR
N
I
R
V
Q
LG
A
T
A
R
FEGKVRGYPEP
Q
I
T
W
YRNGHPLPEGD
H
Y
V
V
D
H
S
I
R
G
I
F
S
L
V
I
K
G
VQEGDSG
K
Y
T
C
EAANDG
G
V
R
Q
V
T
V
E
L
T
VEGNS
L
K
KYSLPSSAKTPGGRLSVPPVEHRPSIWGESPPKFATKP
N
R
V
V
V
REGQT
G
R
F
S
C
K
ITGRPQP
Q
V
T
W
TKG
D
I
H
L
QQNERF
N
M
F
E
KTG
I
Q
Y
L
E
I
Q
N
V
Q
L
ADA
G
I
Y
T
C
T
V
VNSAGKA
S
V
S
A
E
L
T
VQGPDKTDTHAQPLCMPPKPT
T
L
A
T
KAIENSD
F
K
Q
A
TSN
G
I
A
K
E
L
K
STS
T
E
L
M
V
E
T
K
D
RLSA
K
K
E
T
F
YTSREAKDGKQGQNQEANAVPLQESRGTKG
P
Q
V
L
Q
KTS
S
T
I
T
L
Q
A
V
KAQPEPKAEP
Q
T
T
F
I
R
Q
A
EDRKRTVQP
L
M
TTTTQENPSLTGQVSPRSRE
T
E
N
R
A
G
V
R
K
S
V
K
E
E
KREPLGIPPQFESRPQSLEASEG
Q
E
I
K
F
KSKVSGKPKP
D
V
E
W
F
KEGVPIKTGE
G
I
Q
I
Y
EEDG
T
H
C
L
W
L
K
K
A
CLGDSGS
Y
S
C
A
A
FNPRGQTS
T
S
W
L
L
T
VKRP
K
V
E
E
V
A
P
C
F
S
S
V
L
KGCTVSEG
Q
D
F
V
L
Q
C
Y
VGGVPVP
E
I
T
W
L
LNEQ
P
I
Q
Y
A
H
S
T
F
EAG
V
A
K
L
T
V
QDALPEDD
G
I
Y
T
C
L
AENNAGRASC
S
A
Q
V
T
V
KEKKSSKKAEGTQAAKLNK
T
F
A
P
I
F
L
KGLTD
L
K
VMDG
S
Q
V
I
M
T
V
EVSANPC
P
E
I
I
W
LHNGKEIQETEDFHFEKKGN
E
Y
S
L
Y
I
Q
E
VFPEDTGK
Y
T
C
E
A
W
N
ELGETQT
Q
A
T
L
T
V
QEPQDGIQPWFISKPR
S
V
TAAAG
Q
N
V
L
I
S
C
A
IAGDPF
P
T
V
H
W
FKDGQEITPGTG
C
E
I
LQNE
D
I
F
T
L
I
L
R
N
V
Q
S
RHA
G
Q
Y
E
I
Q
L
RNQVGE
C
S
C
Q
V
S
L
M
L
RESSA
S
R
A
E
M
L
R
DGRESASSGERRDGGNYG
A
L
T
FGRTSGFKKSSSETRA
A
E
E
E
Q
E
D
V
R
G
V
L
K
R
R
V
E
T
R
E
H
T
E
E
S
L
R
Q
Q
E
A
E
QL
D
F
R
D
I
LGKKVSTKSF
S
E
E
D
L
K
EI
P
A
E
Q
M
D
F
R
A
N
L
Q
R
QVKPKTL
S
E
E
E
R
KVHAPQQV
D
F
R
S
V
L
AKKGTPKTPLPEKVPPPK
P
A
V
T
D
F
R
S
V
LGAKKKPPAENGSASTPAPNARAGSEAQNATPNSEAPAPKPVVKKEEKNDRKCEHG
C
A
V
VDGGIIGKKAENKPAASKPTPPPSKGTA
P
S
F
T
E
K
L
QDAKVADG
E
K
L
V
L
Q
C
R
ISSDPPA
S
V
S
W
T
LD
S
K
AIKSSK
S
I
V
I
SQEG
T
L
C
S
L
T
I
E
K
VMPEDGGE
Y
K
C
I
AENAAGKA
E
C
A
C
K
V
L
V
EDTSSTKAAKP
A
E
KKTKKPKTTLPPVLSTESSEATVKKKPAPKTPPKAATP
P
Q
ITQFPEDRKVRAG
E
S
V
E
L
F
A
K
V
VGTAP
I
T
C
T
W
M
K
F
R
K
Q
IQEN
E
Y
I
K
I
ENAENS
S
K
L
T
ISSTKQEHC
G
C
Y
T
L
V
V
ENKLGS
R
Q
A
Q
V
N
L
T
V
V
DKPDPPAGT
P
C
A
S
DIRSS
S
L
T
L
S
W
YGSSYDGG
S
A
V
Q
S
Y
T
V
E
I
W
NSVDNKWT
D
L
T
T
CRSTSF
N
V
Q
D
LQADR
E
Y
K
F
R
V
R
A
A
N
V
YGISEPSQE
S
E
V
V
KVG
E
K
Q
E
E
E
L
K
E
E
E
AELSDDEGKE
T
E
V
N
Y
R
T
V
T
INT
E
Q
K
V
S
D
V
Y
N
I
E
--
E
R
LGSG
K
F
G
Q
V
F
R
L
V
E
K
KTGK
V
W
A
G
K
F
F
--
K
A
YSA
K
------
E
------
K
E
N
I
R
D
E
I
S
I
M
N
C
LHH
P
K
L
V
Q
C
V
D
A
F
E
EKA
N
I
V
M
V
L
E
MVS
G
G
E
L
F
E
R
I
I
DEDFEL
T
E
R
E
C
I
K
Y
M
R
Q
I
S
E
G
V
E
Y
I
H
KQ
G
I
V
H
L
DLKPE
N
I
M
C
VNKT--G
T
--
S
I
K
L
I
D
F
G
L
A
R
R
L
ESAG
S
L
K
V
L
FG---TPEFVAPEVINYEPIGYETD
M
W
S
I
G
V
I
C
Y
I
L
V
SGL
S
P
FMGDNDNE
T
L
ANVTSATWDFD
D
E
A
F
D
E
I
S
D
D
A
K
D
F
I
S
N
L
L
K
K
D
M
K
S
RL
N
C
T
Q
C
L
QHPWLQ-K-DT--KN
M
E
A
K
KL
S
K
---
D
R
M
K
---
K
Y
M
A
R
R
K
W
Q
KT
G
H
A
V
R
A
I
G
R
L
S
S
M
A
M
ISGMSGRKASGSSPTSPINADKVE
N
E
D
A
F
L
E
E
V
A
EEKPHVK
P
Y
F
T
K
T
I
L
D
M
E
VVEGSA
A
R
F
D
C
K
IEGYPDP
E
V
M
W
YKDDQPVKES
R
H
F
Q
I
D
YDEEGN
C
S
L
T
I
S
E
VCGDDDA
K
Y
T
C
K
A
V
N
SLGE
A
T
C
T
A
E
L
L
V
E
T
MGKEGEGEGEGEED
E
E
EEEE
4
PsiBlast_PDB
67.76
52%
-83
- C2 -
2X4F
4
MYLK4_HUMAN
A:
[74-346]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
H
R
I
V
T
A
K
-
Q
G
A
V
N
S
F
Y
T
V
S
KT
E
I
L
G
-----
Q
V
H
K
C
E
E
T
A
T
G
L
K
L
A
A
K
I
I
--
K
T
R
G
M
K
------
D
------
K
E
E
V
K
N
E
I
S
V
M
N
Q
L
D
H
A
N
L
I
Q
L
Y
D
A
F
E
S
K
N
D
I
V
L
V
M
E
Y
V
D
G
G
E
L
F
D
R
I
I
D
E
S
Y
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
D
L
K
P
E
N
I
L
C
V
N
R
D
--
A
K
--
Q
I
K
I
I
D
F
G
L
A
R
R
Y
K
P
R
E
K
L
K
V
N
F
G
---
T
P
E
F
L
A
P
E
V
V
N
Y
D
F
V
S
F
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
S
G
L
S
P
F
L
G
D
N
D
A
E
T
L
N
N
I
L
A
C
R
W
D
L
E
D
E
E
F
Q
D
I
S
E
E
A
K
E
F
I
S
K
L
L
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
67.35
43%
-66
- C2 -
2CKE
1
DAPK2_HUMAN
A:
[2-302]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
P
F
K
Q
Q
K
V
E
D
F
Y
D
I
G
--
E
E
L
G
S
G
Q
F
A
I
V
K
K
C
R
E
K
S
T
G
L
E
Y
A
A
K
F
I
--
K
K
R
Q
S
R
ASR
R
G
V
S
------
R
E
E
I
E
R
E
V
S
I
L
R
Q
V
L
H
H
N
V
I
T
L
H
D
V
Y
E
N
R
T
D
V
V
L
I
L
E
L
V
S
G
G
E
L
F
D
F
L
A
Q
K
E
-
S
L
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
L
L
D
K
N
--
I
P
I
P
H
I
K
L
I
D
F
G
L
A
H
E
I
E
D
G
V
E
F
K
N
I
F
G
---
T
P
E
F
V
A
P
E
I
V
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
T
L
A
N
I
T
S
V
S
Y
D
F
D
E
E
F
F
S
H
T
S
E
L
A
K
D
F
I
R
K
L
L
V
K
E
T
R
K
R
L
T
I
Q
E
A
L
R
H
P
W
I
T
-
P
V
D
N
--
Q
Q
A
M
V
R
R
E
S
V
VN
L
E
N
F
R
---
K
Q
Y
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
66.70
43%
-65
- C2 -
2YAA
1
DAPK2_MOUSE
A:
[3-302]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
F
K
Q
Q
K
V
E
D
F
Y
D
I
G
--
E
E
L
G
S
G
Q
F
A
I
V
K
K
C
R
E
K
S
T
G
L
E
Y
A
A
K
F
I
--
K
K
R
Q
S
R
------
A
SRRGVC
R
E
E
I
E
R
E
V
S
I
L
R
Q
V
L
H
P
N
I
I
T
L
H
D
V
Y
E
N
R
T
D
V
V
L
I
L
E
L
V
S
G
G
E
L
F
D
F
L
A
Q
K
E
-
S
L
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
L
L
D
K
N
--
I
P
I
P
H
I
K
L
I
D
F
G
L
A
H
E
I
E
D
G
V
E
F
K
N
I
F
G
---
T
P
E
F
V
A
P
E
I
V
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
T
L
A
N
I
T
A
V
S
Y
D
F
D
E
E
F
F
S
Q
T
S
E
L
A
K
D
F
I
R
K
L
L
V
K
E
T
R
K
R
L
T
I
Q
E
A
L
R
H
P
W
I
T
-
P
V
D
T
--
Q
Q
A
M
V
R
R
E
S
V
VN
L
E
N
F
K
---
K
Q
Y
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
64.98
43%
-52
- C2 -
2XUU
1
DAPK1_HUMAN
A:
[2-302]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
F
R
Q
E
N
V
D
D
Y
Y
D
T
G
--
E
E
L
G
S
G
Q
F
A
V
V
K
K
C
R
E
K
S
T
G
L
Q
Y
A
A
K
F
I
--
K
K
R
R
T
K
------
S
SRRGVS
R
E
D
I
E
R
E
V
S
I
L
K
E
I
Q
H
P
N
V
I
T
L
H
E
V
Y
E
N
K
T
D
V
I
L
I
L
E
L
V
A
G
G
E
L
F
D
F
L
A
E
K
E
-
S
L
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
L
Q
I
A
H
F
D
L
K
P
E
N
I
M
L
L
D
R
N
VP
K
P
--
R
I
K
I
I
D
F
G
L
A
H
K
I
D
F
G
N
E
F
K
N
I
F
G
---
T
P
A
F
V
A
P
E
I
V
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
T
L
A
N
V
S
A
V
N
Y
E
F
E
D
E
Y
F
S
N
T
S
A
L
A
K
D
F
I
R
R
L
L
V
K
D
P
K
K
R
M
T
I
Q
D
S
L
Q
H
P
W
I
K
P
K
-
D
T
--
Q
Q
A
L
S
R
K
A
S
A
---
V
N
M
E
K
F
K
K
F
A
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
62.03
34%
-58
- C2 -
2VN9
2
KCC2D_HUMAN
A:
[2-295]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
D
E
Y
Q
L
F
--
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
NT
K
K
L
S
A
R
------
D
------
H
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
-
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
S
K
S
K-
G
A
--
A
V
K
L
A
D
F
G
L
A
--
I
E
V
Q
G
D
Q
Q
A
W
F
G
FAG
T
P
G
Y
L
S
P
E
V
L
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
T
A
S
E
A
L
K
H
P
W
I
C
-
Q
-
R
S
TV
A
S
M
M
H
R
Q
E
T
V
---
D
C
L
K
---
K
F
N
A
R
R
K
L
K
G
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
60.68
32%
-67
- C2 -
2WEL
7
KCC2D_HUMAN
A:
[2-308]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
D
E
Y
Q
L
F
--
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
NT
K
K
L
S
A
R
------
D
------
H
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
-
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
S
K
S
K-
G
A
--
A
V
K
L
A
D
F
G
L
A
--
I
E
V
Q
G
D
Q
Q
A
W
F
G
FAG
T
P
G
Y
L
S
P
E
V
L
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
T
A
S
E
A
L
K
H
P
W
I
C
-
Q
-
R
----
S
M
M
H
R
Q
E
T
V
---
D
C
L
K
---
K
F
N
A
R
R
K
L
K
G
A
I
--------
L
T
T
M
L
A
T
R
N
F
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------