Atome 2 Filter

@TOME V2.3
(Nov 2016)

Ref. - - Doc.

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Values color: [ Good | Correct | Middling | Bad ]

Sequence color : MutatedHelixStrandConserved

Query sequence : PF00069_STK4_H: (2014-08-20 )
METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF

Atome Classification :

	(20 SA)									.........10........20........30........40........50........60...---.---.--...70---....-....80........90........100.......110....----...120.......130.......140.-......150.......160.......170.......180.......190....-----.-----..200.......210.......220.......230....-----------.....240....--...250.......260.......270.......280-........290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.....
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE---S---D--LQEII---KEIS-IMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRL----RNKTLTEDEIATILQSTLKGLEYLHFM-RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----Q-----EIGYNCVADIWSLGITAIEMAEGKPPYADIHPM--RAIF-----------MIPTNPPPTFRK--PELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF-V-RSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF
41	HHSearch	67.97	55%	-93	- C1 -	3A7I		STK24_HUMAN	A:[14-295]	-------------------QNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAED---E--IEDIQ---QEIT-VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL------EPGPLDETQIATILREILKGLDYLHSE-KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----K-----QSAYDSKADIWSLGITAIELARGEPPHSELHPM--KVLF-----------LIPKNNPPTL----EGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKF-ILRNAKKTSYLTELIDRYKRWK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39	HHSearch	66.29	44%	-99	- C1 -	3FXZ		?	A:[17-293]	------------------------DPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIRQMNLQ---QQP-K--KELII---NEIL-VMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALEFLHSN-QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV-----T-----RKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPL--RALY-----------LIATNGTPELQN--PEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF-L-KIAKPLSSLTPLIAAAKEAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7	PsiBlast_PDB	65.64	52%	-90	- C1 -	3A7J		STK24_HUMAN	A:[15-299]	--------------------NLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDL--L----EPGPLDETQIATILREILKGLDYLHSE-KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----K-----QSAYDSKADIWSLGITAIELARGEPPHSELHPM--KVLF-----------LIPKNNPPTLEG--N--YSKPLKEFVEACLNKEPSFRPTAKELLKHKF-ILRNAKKTSYLTELID-----RYKRWKAEQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9	PsiBlast_PDB	64.61	53%	-91	- C1 -	3CKX		STK24_HUMAN	A:[5-283]	-------------------------PEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLE---E-------DEIEDIQQEIT-VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDL--L----EPGPLDETQIATILREILKGLDYLHSE-KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----K-----QSAYDSKADIWSLGITAIELARGEPPHSELHPM--KVLF-----------LIPKNNPPTLEG--N--YSKPLKEFVEACLNKEPSFRPTAKELLKHKF-ILRNAKKTSYLTELID-----RYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5	PsiBlast_PDB	64.43	52%	-86	- C1 -	3A7H		STK24_HUMAN	A:[15-298]	--------------------NLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDL--L----EPGPLDETQIATILREILKGLDYLHSE-KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----K-----QSAYDSKADIWSLGITAIELARGEPPHSELHPM--KVLF-----------LIPKNNPPTLEG--N--YSKPLKEFVEACLNKEPSFRPTAKELLKHKF-ILRNAKKTSYLTELID-----RYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10	PsiBlast_PDB	64.38	54%	-91	- C1 -	2XIK		STK25_HUMAN	A:[17-286]	-------------------------PEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLE---E---A--E-EIEDIQQEIT-VLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDL--L----KPGPLEETYIATILREILKGLDYLHSE-RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----K-----QSAYDFKADIWSLGITAIELAKGEPPNSDLHPM--RVLF-----------LIPKNSPPTLEG--QH--SKPFKEFVEACLNKDPRFRPTAKELLKHKF-ITRYTKKTSFLTELID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17	PsiBlast_PDB	64.33	45%	-105	- C1 -	4AOT		STK10_HUMAN	A:[17-295]	-------------------------PNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETK---S---EEELEDYI---VEIE-ILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLE----LDRGLTEPQIQVVCRQMLEALNFLHSK-RIIHRDLKAGNVLMTLEGDIRLADFGVSA-------------GTPYWMAPEVVM-------------YDYKADIWSLGITLIEMAQIEPPHHELNPM--RVLL-----------KIAKSDPPTLLT--PSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPF-V-SSITSNKALRELVAEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36	HHSearch	64.09	45%	-98	- C1 -	2J7T		STK10_HUMAN	A:[16-297]	------------------------DPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIE-----E---E--LEDYI---VEIE-ILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLE----LDRGLTEPQIQVVCRQMLEALNFLHSK-RIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQK----IGTPYWMAPEVV-----MCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPM--RVLL-----------KIAKSDPPTLLT--PSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPF-V-SSITSNKALRELVAEAKA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47	HHSearch	63.66	38%	-98	- C1 -	4FIE		PAK4_HUMAN	A:[151-420]	---------------------------SYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLR---KQQ-R--RELLF---NEVV-IMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVT------HTRMNEEQIAAVCLAVLQALSVLHAQ-GVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELI-----S-----RLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPL--KAMK-----------MIRDNLPPRLKN--LHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPF-L-AKAGPPASIVPLMRQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13	PsiBlast_PDB	61.61	54%	-98	- C1 -	4FZD		MST4_HUMAN	B:[6-275]	-------------------------PEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDL--L----RAGPFDEFQIATMLKEILKGLDYLHSE-KKIHRDIKAANVLLSEQGDVKLAAFGVAGQLT------NTFVGTPFWMAPEVI-----Q-----QSAYDSKADIWSLGITAIELAKGEPPNSDMHPM--RVLF-----------LIPKNNPPTLVG--D--FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV-KNSKKTSYLTELID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12	PsiBlast_PDB	61.04	54%	-92	- C1 -	4FZA		MST4_HUMAN	B:[6-275]	-------------------------PEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDL--L----RAGPFDEFQIATMLKEILKGLDYLHSE-KKIHRDIKAANVLLSEQGDVKLAAFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----Q-----QSAYDSKADIWSLGITAIELAKGEPPNSDMHPM--RVLF-----------LIPKNNPPTLVG--D--FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV-KNSKKTSYLTELID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14	PsiBlast_PDB	60.29	54%	-89	- C1 -	4FZF		?	B:[6-275]	-------------------------PEELFTKLERIGKG--GEVFKGIDNRTQQVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDL--L----RAGPFDEFQIATMLKEILKGLDYLHSE-KKIHRDIKAANVLLSEQGDVKLAAFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----Q-----QSAYDSKADIWSLGITAIELAKGEPPNSDMHPM--RVLF-----------LIPKNNPPTLVG--D--FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV-KNSKKTSYLTELID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19	PsiBlast_PDB	59.41	45%	-99	- C1 -	4BC6		STK10_HUMAN	A:[9-287]	-------------------------PNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETK---S---EEELEDYI---VEIE-ILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLE----LDRGLTEPQIQVVCRQMLEALNFLHSK-RIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQ--------PYWMAPEVVMCETMK-----DTPYDYKADIWSLGITLIEMAQIEPPHHELNPM--RVLL-----------KIAKSDPPTLLT--PSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPF-V-SSITSNKALRELVAEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18	PsiBlast_PDB	57.60	45%	-101	- C1 -	4EQU		STK10_HUMAN	A:[17-295]	-------------------------PNEVWEIVGELG-----KVYKAKNKETGALAAAKVIE------------LEDYI---VEIE-ILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLE----LDRGLTEPQIQVVCRQMLEALNFLHSK-RIIHRDLKAGNVLMTLEGDIRLADFGVSAKNL---------IGTPYWMAPEVVMCETMK-----DTPYDYKADIWSLGITLIEMAQIEPPHHELNPM--RVLL-----------KIAKSDPPTLLT--PSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPF-V-SSITSNKALRELVAEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11	PsiBlast_PDB	57.50	54%	-99	- C1 -	3GGF		MST4_HUMAN	A:[21-290]	-------------------------PEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLE---E---A--EDEIEDIQQEIT-VLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDL--L----RAGPFDEFQIATMLKEILKGLDYLHSE-KKIHRDIKAANVLLSEQGDVKLADFGVA---------RNTFVGTPFWMAPEVI-----Q-----QSAYDSKADIWSLGITAIELAKGEPPNSDMHPM--RVLF-----------LIPKNNPPTLVG--D--FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV-KNSKKTSYLTELID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43	HHSearch	55.45	36%	-103	- C1 -	3EQC		MP2K1_HUMAN	A:[32-333]	--------------------------DDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLE---IKPAI--RNQII---RELQ-VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKK-----AGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA-----VGTRSYMSPERL-----Q-----GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCPMAIFELLDYIVNEPPPKL-P--SGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF-I-KRSDA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20	PsiBlast_PDB	54.97	43%	-94	- C1 -	2J51		SLK_HUMAN	A:[34-312]	------------------------NPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTK---S---EEELEDYM---VEID-ILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLE----LERPLTESQIQVVCKQTLDALNYLHDN-KIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSK-----DRPYDYKADVWSLGITLIEMAEIEPPHHELNPM--RVLL-----------KIAKSEPPTLAQ--PSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF-V-TVDSNKPI-RELIAEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40	HHSearch	52.45	38%	-92	- C1 -	4JDI		?	A:[72-342]	-------------------------PRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLR---KQQ-R--RELLF---NEVV-IMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIV------THTRMNEEQIAAVCLAVLQALSVLHAQ-GVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELI-----S-----RLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPL--KAMK-----------MIRDNLPPRLKN--LHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPF-L-AKAGPPASIVPLMRQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48	HHSearch	49.16	39%	-94	* C1 *	4KS7			A:[20-287]	------------------------DPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLR---KQQ-R--RELLF---NEVV-IMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIV------SQVRLNEEQIATVCEAVLQALAYLHAQ-GVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI-----S-----RSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPV--QAMK-----------RLRDSPPPKLKN--SHKVSPVLRDFLERMLVRDPQERATAQELLDHPF-L-LQTGLPECLVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52	HHSearch	38.67	36%	-106	- C1 -	3ALN		MP2K4_HUMAN	A:[22-292]	---------------------------EDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEK---E--QKQLL---MDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMST-SFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQ-------------------------------------YDVRSDVWSLGITLYELATGRFPYPKW--------T-----------QVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPF-I-LMY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------