@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00090_ATS5_H: (2014-08-24 )
MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC
Atome Classification :
(14 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.....-..440.......450.......460.......470.......480.......490.......500.......510........520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLL
G
W
A
S
L
L
L
C
A
F
RL
P
L
AAVGPAATPAQDKAGQPPTAAAAAQPRRRQ
G
E
E
V
Q
E
RAEPPGHPH
P
L
A
Q
R
R
R
SK
G
L
V
Q
N
I
D
Q
L
YSGG
G
K
V
G
Y
L
V
YAGG
R
R
F
L
L
D
LERDGSVG
I
A
G
F
V
PAGGGTSAPWRHR
S
H
C
F
Y
RGTVDGSPR
S
L
A
V
F
D
L
CGGL
D
G
F
F
A
V
K
H
A
R
Y
T
L
K
P
L
LRGPWAEEEK
G
R
V
YGDGS
A
R
I
L
H
V
Y
TREGFSFEALPPRASCETPASTPEAHEHAPAHSNPS
G
R
A
A
L
A
S
Q
L
L
D
Q
SALSPAGGS
G
P
Q
T
W
W
R
R
R
R
R
S
ISRA
R
Q
V
E
L
L
L
VA
D
A
S
M
A
R
L
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
HA
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
LGDKDKS
L
E
VSK
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
HNQLGD
D
H
E
E
HY
D
A
A
I
L
F
T
R
E
D
LCGHHSCDTLGMA
D
V
GTICSPER
S
C
A
V
IEDDG
L
H
A
A
F
T
V
A
H
E
I
G
H
L
LGLSH
D
D
S
K
F
C
E
E
TFGS
T
E
D
K
R
-
L
M
S
S
I
L
T
S
IDASKPWSKC
T
S
A
T
I
T
E
F
L
DDGHG
N
C
L
LDL
P
R
K
QIL
G
P
E
ELPGQTYDAT
Q
Q
CN
L
T
FGPEYSVCP
G
M
-
D
V
C
A
R
L
W
C
A
V
VRQG
Q
M
V
C
L
TKKLPAVEGTPCGK
G
R
I
C
L
QGKCV
D
K
T
K
K
K
Y
YSTSSHGNWGSWGSW
G
Q
C
S
RSCGGG
V
Q
F
A
Y
R
HCNNPAPRNNGRYCTG
K
R
A
I
Y
R
SCSLMPCPPNGKSF
R
H
E
QCEAKNGYQS
D
A
K
G
V
K
T
F
V
E
W
V
P
K
Y
AGV
L
P
A
D
V
C
K
L
T
C
R
AKG
T
G
Y
Y
V
V
FSPKVTDG
T
E
C
R
L
YSN
S
V
C
V
R
G
K
C
VRTGCDGIIGSK
L
Q
YDKCGVCGGDNS
S
C
T
K
I
V
G
TFNKKSKGYT
D
V
V
RIPEGA
T
H
I
K
V
R
Q
F
KAKDQ
T
R
F
T
A
Y
L
A
L
KKKNG
E
Y
L
I
N
G
K
Y
M
ISTS
E
T
I
I
D
IN
G
T
V
MNYSGWS
H
R
D
D
F
L
HGMGYSAT
K
E
I
L
I
V
Q
I
L
ATDPTK
P
L
D
V
R
Y
S
F
F
VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGW
H
T
R
T
V
Q
CQDGNRKLAKGCPLSQ
R
P
S
A
F
K
Q
C
L
LKKC
1
PsiBlast_PDB
97.96
100%
-117
- C2 -
2RJQ
2
ATS5_HUMAN
A:
[3-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
L
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
L
G
P
E
E
L
P
G
Q
T
Y
D
A
T
Q
Q
C
N
L
T
F
G
P
E
Y
S
V
C
P
G
M
-
D
V
C
A
R
L
W
C
A
V
V
R
Q
G
Q
M
V
C
L
T
K
K
L
P
A
V
E
G
T
P
C
G
K
G
R
I
C
L
Q
G
K
C
V
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
84.06
55%
-103
- C2 -
3Q2G
1
ATS1_HUMAN
A:
[3-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
V
E
T
M
L
V
A
D
Q
S
M
A
E
F
H
G
S
G
L
K
H
Y
L
L
T
L
F
S
V
A
A
R
L
Y
K
H
P
S
I
R
N
S
V
S
L
V
V
V
K
I
L
V
I
H
D
E
Q
K
G
P
E
V
T
S
N
A
A
L
T
L
R
N
F
C
N
W
Q
K
Q
H
N
P
P
S
D
R
D
A
E
H
Y
D
T
A
I
L
F
T
R
Q
D
L
C
G
S
Q
T
C
D
T
L
G
M
A
D
V
G
T
V
C
D
P
S
R
S
C
S
V
I
E
D
D
G
L
Q
A
A
F
T
T
A
H
E
L
G
H
V
F
N
M
P
H
D
D
A
K
Q
C
A
S
L
N
-----
S
H
-
M
M
A
S
M
L
S
N
L
D
H
S
Q
P
W
S
P
C
S
A
Y
M
I
T
S
F
L
D
N
G
H
G
E
C
L
M
D
K
P
Q
N
P
I
Q
L
P
G
D
L
P
G
T
S
Y
D
A
N
R
Q
C
Q
F
T
F
G
E
D
S
K
H
C
P
----
T
C
S
T
L
W
C
T
G
-----
L
V
C
Q
T
K
H
F
P
W
A
D
G
T
S
C
G
E
G
K
W
C
I
N
G
K
C
V
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
83.61
55%
-102
- C2 -
3Q2H
1
ATS1_HUMAN
A:
[3-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
V
E
T
M
L
V
A
D
Q
S
M
A
E
F
H
G
S
G
L
K
H
Y
L
L
T
L
F
S
V
A
A
R
L
Y
K
H
P
S
I
R
N
S
V
S
L
V
V
V
K
I
L
V
I
H
D
E
Q
K
G
P
E
V
T
S
N
A
A
L
T
L
R
N
F
C
N
W
Q
K
Q
H
N
P
P
S
D
R
D
A
E
H
Y
D
T
A
I
L
F
T
R
Q
D
L
C
G
S
Q
T
C
D
T
L
G
M
A
D
V
G
T
V
C
D
P
S
R
S
C
S
V
I
E
D
D
G
L
Q
A
A
F
T
T
A
H
E
L
G
H
V
F
N
M
P
H
D
D
A
K
Q
C
A
S
L
N
----
D
S
H
-
M
M
A
S
M
L
S
N
L
D
H
S
Q
P
W
S
P
C
S
A
Y
M
I
T
S
F
L
D
N
G
H
G
E
C
L
M
D
K
P
Q
N
P
I
Q
L
P
G
D
L
P
G
T
S
Y
D
A
N
R
Q
C
Q
F
T
F
G
E
D
S
K
H
C
P
----
T
C
S
T
L
W
C
T
G
----
V
L
V
C
Q
T
K
H
F
P
W
A
D
G
T
S
C
G
E
G
K
W
C
I
N
G
K
C
V
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
83.15
54%
-96
- C2 -
2JIH
1
ATS1_HUMAN
A:
[4-296]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
H
R
Y
V
E
T
M
L
V
A
D
Q
S
M
A
E
F
H
G
S
G
L
K
H
Y
L
L
T
L
F
S
V
A
A
R
L
Y
K
H
P
S
I
R
N
S
V
S
L
V
V
V
K
I
L
V
I
H
D
E
Q
K
G
P
E
V
T
S
N
A
A
L
T
L
R
N
F
C
N
W
Q
K
Q
H
N
P
P
S
D
R
D
A
E
H
Y
D
T
A
I
L
F
T
R
Q
D
L
C
G
S
Q
T
C
D
T
L
G
M
A
D
V
G
T
V
C
D
P
S
R
S
C
S
V
I
E
D
D
G
L
Q
A
A
F
T
T
A
H
E
L
G
H
V
F
N
M
P
H
D
D
A
K
Q
C
A
S
L
N
----
D
S
H
-
M
M
A
S
M
L
S
N
L
D
H
S
Q
P
W
S
P
C
S
A
Y
M
I
T
S
F
L
D
N
G
H
G
E
C
L
M
D
K
P
Q
N
P
I
Q
L
P
G
D
L
P
G
T
S
Y
D
A
N
R
Q
C
Q
F
T
F
G
E
D
S
K
H
C
P
----
T
C
S
T
L
W
C
T
G
----
V
L
V
C
Q
T
K
H
F
P
W
A
D
G
T
S
C
G
E
G
K
W
C
I
N
G
K
C
V
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
81.59
45%
-103
- C2 -
2RJP
1
ATS4_HUMAN
A:
[3-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
S
R
F
V
E
T
L
V
V
A
D
D
K
M
A
A
F
H
G
A
G
L
K
R
Y
L
L
T
V
M
A
A
A
A
K
A
F
K
H
P
S
I
R
N
P
V
S
L
V
V
T
R
L
V
I
L
----
E
G
P
Q
V
G
P
S
A
A
Q
T
L
R
S
F
C
A
W
Q
R
G
L
N
T
P
E
D
S
D
P
D
H
F
D
T
A
I
L
F
T
R
Q
D
L
C
G
V
S
T
C
D
T
L
G
M
A
D
V
G
T
V
C
D
P
A
R
S
C
A
I
V
E
D
D
G
L
Q
S
A
F
T
A
A
H
Q
L
G
H
V
F
N
M
L
H
D
N
S
K
P
C
I
S
L
N
G
P
L
S
T
S
R
H
V
M
A
P
V
M
A
H
V
D
P
E
E
P
W
S
P
C
S
A
R
F
I
T
D
F
L
D
N
G
Y
G
H
C
L
L
D
K
P
E
A
P
L
H
L
P
V
T
F
P
G
K
D
Y
D
A
D
R
Q
C
Q
L
T
F
G
P
D
S
R
H
C
P
Q
L
P
P
P
C
A
A
L
W
C
S
G
H
L
N
G
H
A
M
C
Q
T
K
H
S
P
W
A
D
G
T
P
C
G
P
A
Q
A
C
M
G
G
R
C
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.23
99%
-105
- C2 -
3HY9
1
ATS5_HUMAN
A:
[5-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
79.14
99%
-109
- C2 -
3HY7
1
B:
[5-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
78.89
99%
-107
- C2 -
3HY9
1
B:
[3-221]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
78.83
99%
-109
- C2 -
3B8Z
1
B:
[1-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
78.69
99%
-108
- C2 -
3HYG
1
B:
[5-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.61
99%
-105
- C2 -
3HYG
1
ATS5_HUMAN
A:
[5-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
78.45
99%
-109
- C2 -
3LJT
2
A:
[2-218]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
78.28
99%
-104
- C2 -
3B8Z
1
ATS5_HUMAN
A:
[1-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.47
99%
-106
- C2 -
3HY7
1
ATS5_HUMAN
A:
[5-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
A
R
Q
V
E
L
L
L
V
A
D
A
S
M
A
R
K
Y
G
R
G
L
Q
H
Y
L
L
T
L
A
S
I
A
N
R
L
Y
S
H
A
S
I
E
N
H
I
R
L
A
V
V
K
V
V
V
L
G
D
K
D
K
S
L
E
V
S
K
N
A
A
T
T
L
K
N
F
C
K
W
Q
H
Q
H
N
Q
L
G
D
D
H
E
E
H
Y
D
A
A
I
L
F
T
R
E
D
L
C
G
H
H
S
C
D
T
L
G
M
A
D
V
G
T
I
C
S
P
E
R
S
C
A
V
I
E
D
D
G
L
H
A
A
F
T
V
A
H
E
I
G
H
L
L
G
L
S
H
D
D
S
K
F
C
E
E
T
F
G
S
T
E
D
K
R
-
L
M
S
S
I
L
T
S
I
D
A
S
K
P
W
S
K
C
T
S
A
T
I
T
E
F
L
D
D
G
H
G
N
C
L
L
D
L
P
R
K
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------