@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : PF00105_ESR2_H: (2014-08-25 )
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ

Atome Classification :

(61 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.-.......290.......300.......310.......320.......330.......340.......350.----......360.......370.......380.....-..390.......400.......410.....-..-420.......430.......440.......450.......460.......470.......480...---....490.......500.......510.......520.......530
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTAT-QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
34 PsiBlast_CBE 96.40100%-156 - C4 -4J24 ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
32 PsiBlast_CBE 95.18100%-159 - C4 -4J24 ESR2_HUMAN C:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
28 PsiBlast_CBE 94.80100%-159 - C4 -1U3R B:[3-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
42 PsiBlast_CBE 94.37100%-160 - C4 -2YJD ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
3 PsiBlast_PDB 94.37100%-158 - C4 -1QKM A:[6-246] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
36 PsiBlast_CBE 94.32100%-158 - C4 -3OMQ ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
31 PsiBlast_CBE 94.11100%-161 - C4 -4J24 D:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS---------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
33 PsiBlast_CBE 94.06100%-157 - C4 -4J24 ESR2_HUMAN B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
19 PsiBlast_PDB 93.95100%-158 - C4 -3OLS ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
41 PsiBlast_CBE 93.76100%-158 - C4 -2YJD B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
47 PsiBlast_CBE 93.73100%-156 - C4 -1U3S B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
20 PsiBlast_PDB 93.61100%-156 - C4 -3OMO ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
12 PsiBlast_PDB 93.52100%-160 - C4 -2GIU A:[1-241] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKC-EGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM----VV---PVYDLLLEMLNAHVL------------------------------
11 PsiBlast_PDB 93.51100%-156 - C4 -1U3R ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM--------QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
38 PsiBlast_CBE 93.49100%-157 - C4 -3OMP ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
30 PsiBlast_CBE 93.22100%-155 - C4 -4J26 ESR2_HUMAN A:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS------------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
18 PsiBlast_PDB 93.21100%-152 - C4 -1U3S ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY----------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
37 PsiBlast_CBE 93.08100%-161 - C4 -3OMP B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTA----------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
15 PsiBlast_PDB 93.05100%-157 - C4 -1X7B ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
40 PsiBlast_CBE 93.01100%-159 - C4 -3OLS B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTA----------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
39 PsiBlast_CBE 92.97100%-161 - C4 -3OMO B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTA----------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
35 PsiBlast_CBE 92.97100%-160 - C4 -3OMQ B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTA----------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
10 PsiBlast_PDB 92.84100%-156 - C4 -1U9E ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
45 PsiBlast_CBE 92.64100%-155 - C4 -1X78 B:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
56 PsiBlast_CBE 92.5999%-162 - C4 -2YLY ESR2_HUMAN A:[2-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
29 PsiBlast_CBE 92.46100%-155 - C4 -4J26 B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM-----------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
74 HHSearch 92.44100%-159 - C4 -1YYE ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
52 PsiBlast_CBE 92.43100%-157 - C4 -2NV7 ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
54 PsiBlast_CBE 92.3199%-154 - C4 -1ZAF ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
17 PsiBlast_PDB 92.24100%-157 - C4 -1U3Q ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
14 PsiBlast_PDB 92.24100%-157 - C4 -1X78 ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
9 PsiBlast_PDB 92.24100%-152 - C4 -1NDE A:[15-254] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRPS--FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY----AT-QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCK------PVYDLLLEMLNAHVL------------------------------
49 PsiBlast_CBE 92.22100%-159 - C4 -1U3Q ESR2_HUMAN C:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
44 PsiBlast_CBE 92.15100%-155 - C4 -1X7B B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
53 PsiBlast_CBE 92.1499%-157 - C4 -1ZAF B:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
16 PsiBlast_PDB 91.68100%-158 - C4 -1X7J ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
48 PsiBlast_CBE 91.64100%-161 - C4 -1U3Q D:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
24 PsiBlast_CBE 91.63100%-159 - C4 -2Z4B B:[12-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAHVL------------------------------
43 PsiBlast_CBE 91.62100%-156 - C4 -1X7J B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
51 PsiBlast_CBE 91.61100%-154 - C4 -2NV7 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
75 HHSearch 91.6097%-158 - C4 -1L2J ESR2_HUMAN A:[27-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SR-----TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS----LVTAT-QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
7 PsiBlast_PDB 91.55100%-157 - C4 -2Z4B ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
5 PsiBlast_PDB 91.54100%-158 - C4 -2I0G ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
22 PsiBlast_CBE 91.36100%-160 - C4 -1YY4 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
13 PsiBlast_PDB 91.35100%-156 - C4 -1X76 ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
46 PsiBlast_CBE 91.18100%-155 - C4 -1X76 B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
57 PsiBlast_CBE 91.1091%-158 - C4 -2J7Y A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-V-S-----FTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
27 PsiBlast_CBE 91.10100%-157 - C4 -2I0G B:[12-250] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
55 PsiBlast_CBE 91.0499%-154 - C4 -2YLY B:[1-238] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
8 PsiBlast_PDB 90.95100%-159 - C4 -2QTU ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK---------VYDLLLEMLNAH--------------------------------
25 PsiBlast_CBE 90.94100%-161 - C4 -2QTU B:[12-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I-SRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK---------VYDLLLEMLNAHVL------------------------------
58 PsiBlast_CBE 90.7891%-157 - C4 -2J7X A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-V-S---MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
21 PsiBlast_CBE 90.54100%-153 - C4 -1YYE B:[1-234] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLN----------------------------------
23 PsiBlast_CBE 90.4197%-162 - C4 -1L2J ESR2_HUMAN B:[21-263] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRELLLDALSPEQLVLTLLEAEPPHV---------------MMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM--LVTAT-QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM-----V---PVYDLLLEMLNA---------------------------------
1 PsiBlast_PDB 90.32100%-154 - C4 -1YY4 ESR2_HUMAN A:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
50 PsiBlast_CBE 90.20100%-159 - C4 -1U3Q ESR2_HUMAN B:[1-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I-SRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
59 PsiBlast_CBE 88.9991%-153 - C4 -1QKN A:[8-243] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-V-SRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLASAN-QE-AESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK-----------DLLLEMLNA---------------------------------
81 HHSearch 85.0058%-152 - C4 -1XPC A:[3-245] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLTADQMVSALLDAEPPILY-SEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKS-LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV---PLYDLLLEMLDAHRLHA----------------------------
60 PsiBlast_CBE 83.7691%-157 - C4 -1HJ1 A:[9-226] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPNVL-V-SRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS----------------SRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK-----------------------------------------------------
77 HHSearch 82.6056%-147 * C4 *2OCF A:[8-251] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALSLTADQMVSALLDAEPPILYSE-YDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT------------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV---PLSDLLLEMLDAHR-------------------------------
62 Fugue 74.5846%-127 - C4 -3ERT A:[13-258] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LALSLTADQMVSALLDAEPP---------------------I---LYSEYDP-------TRPFS--------------EASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSME--HPGKLLFA--PNLLLDRNQGKCVEGMVEIFDMLLATSSRFR-MMNLQGEEFVCLKSIILLNSGVYTFLSST-LKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKC----KNVV---PLYDLLLEMLD--------AHRLHA----------------