@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00105_RORA_H: (2014-08-26 )
MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCILSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Atome Classification :
(12 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......-420.......430.......440.......450.......460.......470.......480.......490.....-..500.......510.......520.......530.......540.......550....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNEGAPGDSDLETEARV
P
W
S
I
M
G
H
C
L
RTGQARMSATPTPAGEGA
R
R
D
E
L
F
G
I
L
Q
I
L
H
Q
C
I
LSSG
D
A
F
V
L
T
G
V
C
CSWRQNGKPPYSQKEDKEVQTGY
M
N
A
Q
I
E
I
I
P
C
K
ICGDKSSG
I
H
Y
G
V
I
T
CE
G
C
K
G
F
F
R
RSQQSNATYSCPRQKN
C
L
IDRTSR
N
R
C
Q
H
C
R
L
Q
K
C
L
A
VGMS
R
D
A
V
K
F
G
R
M
S
K
K
Q
R
D
S
L
Y
A
E
V
Q
K
H
R
M
Q
Q
Q
Q
R
D
HQQQPGEAEPLTP
T
Y
N
ISAN
G
L
T
E
L
H
D
D
L
S
N
Y
IDGHTPEGSKADS
A
V
S
S
F
Y
L
D
IQPSPDQSGLDINGIKPEPICDYTPASGFF
P
Y
C
SFTNGETSPT
V
S
M
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
CQND
Q
I
V
L
L
KAG
S
L
E
V
V
F
I
R
M
C
R
A
FDSQN
N
T
V
Y
FDGKYA-
S
P
D
V
F
K
SLG
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
MHL
T
E
D
E
I
A
L
F
S
A
F
V
L
MSA
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
NHRED-
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
LHF
P
P
L
Y
K
E
L
F
T
S
EFEPAMQIDG
1
PsiBlast_PDB
95.63
100%
-139
- C3 -
1N83
1
A:
[18-258]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
-
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
-
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
------------
2
PsiBlast_PDB
95.07
100%
-139
- C3 -
1S0X
1
A:
[18-258]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
-
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
-
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
------------
36
HHSearch
84.13
63%
-132
- C3 -
1NQ7
2
RORB_RAT
A:
[1-244]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
-
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
-
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
N
-----------
6
PsiBlast_PDB
84.11
53%
-128
- C3 -
4NIE
5
RORG_HUMAN
A:
[17-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
--
S
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
T
----------
35
HHSearch
83.90
53%
-123
- C3 -
3L0L
3
RORG_HUMAN
A:
[2-248]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
--
S
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
3
PsiBlast_PDB
83.24
62%
-132
- C3 -
1K4W
2
RORB_RAT
A:
[8-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
-
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
-
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
------------
4
PsiBlast_PDB
82.78
61%
-130
- C3 -
1N4H
2
RORB_RAT
A:
[8-251]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
-
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
-
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
N
-----------
10
PsiBlast_PDB
82.52
53%
-128
- C3 -
3L0J
2
A:
[2-243]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
--
S
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
9
PsiBlast_PDB
82.20
53%
-130
- C3 -
3KYT
2
A:
[2-243]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
--
S
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
7
PsiBlast_PDB
75.13
52%
-117
- C3 -
4NB6
1
RORG_HUMAN
A:
[7-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
--
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
--------------------------------
11
PsiBlast_PDB
74.20
53%
-123
- C3 -
3B0W
1
RORG_HUMAN
A:
[2-215]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
-
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
--
S
I
L
A
K
L
P
P
K
-
G
K
L
R
S
L
C
S
Q
H
---------------------------------------
22
Fugue
71.02
31%
-112
- C3 -
1BSX
2
THB_HUMAN
A:
[10-260]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
E
P
T
-
D
E
E
W
E
L
I
K
T
V
T
E
A
H
V
A
T
N
A
Q
G
S
H
W
K
Q
K
---
R
K
F
L
P
E
D
I
G
Q
-
A
P
K
V
D
L
E
A
F
S
H
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
C
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
E
T
L
T
L
N
G
E
M
A
V
T
R
G
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
D
L
G
M
S
L
S
S
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
S
D
R
P
G
L
A
C
V
E
R
I
E
K
Y
Q
D
S
F
L
L
A
F
E
H
Y
I
N
Y
R
K
H
H
V
T
H
F
W
P
K
L
L
M
K
V
T
D
L
R
M
I
G
A
C
H
A
S
R
F
L
H
M
K
V
E
C
P
T
---
E
L
F
P
P
L
F
L
E
V
F
E
D
----------