@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00183_HSP82_: (2014-08-30 )
MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTEMEEVD
Atome Classification :
(32 SA)
.........10........20........30........40........50....-----....60........70........80........90........100.......-110--.-........120.......130.......140.......150.......160.-----......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MASE
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
VYS
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
YKSLS
D
P
K
Q-----LETEP
D
L
F
I
R
ITPKP
E
Q
K
V
L
E
I
RDSGIG
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S-A----G-A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
ISKSNDDE
Q
Y
I
W
ESNAG
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
IGR
G
T
I
L
R
L
F
LKD
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
RHSEFVAY
P
I
Q
L
V
V
T
K
E
V
E
KEVPIPEEEKKDEEKKDEEKKDEDDKKP
K
L
E
EV
D
E
E
E
EKKP
K
T
K
K
V
K
E
E
V
Q
E
I
E
E
L
NKTKPLWTRNPSDI
T
Q
E
E
Y
N
A
F
Y
K
S
ISNDWED
P
L
Y
V
K
H
F
SVE
G
Q
L
E
F
R
A
I
L
F
IPKRA
P
F
D
L
F
E
S
KKKKN
N
I
K
L
Y
V
R
R
V
F
ITD
E
A
E
D
L
I
P
E
W
L
S
F
V
K
G
VVDSEDLP
L
N
L
S
R
E
M
L
Q
Q
N
K
I
M
K
V
I
R
K
N
I
V
K
K
L
I
E
A
F
N
E
I
A
E
D
S
E
Q
F
E
K
F
Y
S
A
F
SKN
I
K
L
G
VHEDTQ
N
R
A
A
L
A
K
L
L
RYNSTK
S
V
D
E
L
T
S
L
T
D
Y
V
T
RMPEHQK
N
I
Y
Y
ITGE
S
L
K
A
V
EKSP
F
L
D
A
L
KAK
N
F
E
V
L
F
LTDP
I
D
E
Y
A
F
T
Q
L
K
E
FEG
K
T
L
V
D
ITKDFELEET
D
E
E
K
A
E
R
E
K
E
I
K
E
Y
E
P
L
T
K
A
L
K
E
I
L
G
D
Q
V
E
K
V
V
V
S
Y
K
LLDAPAAIRTGQFGW
S
A
N
M
E
R
I
M
K
A
Q
A
L
R
D
S
S
M
S
S
Y
MSSK
K
T
F
EISPKS
P
I
I
K
E
L
K
K
R
V
DEGGAQDK
T
V
K
D
L
T
K
L
L
Y
E
T
A
L
LTSGFSLDEP
T
S
F
A
S
R
I
N
R
L
I
S
LGLNIDEDEETETAPEASTAA
P
V
E
EVPADTEMEEVD
27
PsiBlast_CBE
51.37
99%
-85
- C2 -
3C11
3
HSP82_YEAST
A:
[21-234]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
A
A
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
51.14
100%
-86
- C2 -
2BRE
1
HSP82_YEAST
B:
[2-219]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
K
E
V
P
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
51.07
100%
-82
- C2 -
1AH8
3
HSP82_YEAST
B:
[2-219]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
K
E
V
P
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
50.93
100%
-91
- C2 -
2VW5
1
HSP82_YEAST
C:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
50.86
100%
-87
- C2 -
2VW5
1
HSP82_YEAST
B:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
50.77
100%
-90
- C2 -
2VW5
1
HSP82_YEAST
D:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
50.77
100%
-86
- C2 -
1A4H
1
HSP82_YEAST
A:
[11-224]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
50.73
100%
-88
- C2 -
2VW5
1
HSP82_YEAST
A:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
50.71
100%
-84
- C2 -
2BRC
1
HSP82_YEAST
A:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
50.62
100%
-86
- C2 -
2XX5
2
HSP82_YEAST
A:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
---
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
50.55
100%
-86
- C2 -
4ASA
1
HSP82_YEAST
A:
[2-214]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
50.54
100%
-84
- C2 -
1AH8
1
HSP82_YEAST
A:
[2-216]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
50.50
100%
-83
- C2 -
1ZW9
1
HSP82_YEAST
A:
[22-234]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
-------
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
50.48
100%
-88
- C2 -
4ASB
1
HSP82_YEAST
A:
[2-214]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
50.47
99%
-86
- C2 -
2WEQ
3
HSP82_YEAST
A:
[2-214]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
I
V
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
50.43
100%
-83
- C2 -
1ZWH
1
HSP82_YEAST
A:
[22-234]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
50.37
100%
-87
- C2 -
1AMW
1
HSP82_YEAST
A:
[2-214]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
50.33
99%
-86
- C2 -
2WEP
1
HSP82_YEAST
A:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
I
V
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
50.25
100%
-86
- C2 -
1BGQ
1
HSP82_YEAST
A:
[12-225]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
50.23
100%
-86
- C2 -
1AM1
1
HSP82_YEAST
A:
[1-213]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
50.22
100%
-88
- C2 -
4ASG
1
HSP82_YEAST
A:
[2-214]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
50.16
100%
-84
- C2 -
2FXS
6
HSP82_YEAST
A:
[22-234]
-
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
49.58
99%
-87
- C2 -
2WER
1
HSP82_YEAST
A:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
I
V
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
49.54
99%
-90
- C2 -
2WER
1
HSP82_YEAST
B:
[1-214]
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
M
S
L
I
I
N
T
V
Y
S
N
K
E
I
F
L
R
E
I
V
S
N
A
S
D
A
L
D
K
I
R
Y
K
S
L
S
D
P
K
Q
-----
L
E
T
E
P
D
L
F
I
R
I
T
P
K
P
E
Q
K
V
L
E
I
R
D
S
G
I
G
M
T
K
A
E
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
S
-
A
----
G
-
A
D
V
S
M
I
G
Q
F
G
V
G
F
Y
S
L
F
L
V
A
D
R
V
Q
V
I
S
K
S
N
D
D
E
Q
Y
I
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
V
-----
N
E
R
I
G
R
G
T
I
L
R
L
F
L
K
D
D
Q
L
E
Y
L
E
E
K
R
I
K
E
V
I
K
R
H
S
E
F
V
A
Y
P
I
Q
L
V
V
T
K
E
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
47.51
71%
-83
- C2 -
3K60
1
?
A:
[2-209]
-
S
T
E
T
F
A
F
N
A
D
I
R
Q
L
M
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
E
S
I
T
D
T
Q
K
-----
L
S
A
E
P
E
F
F
I
R
I
I
P
D
K
T
N
N
T
L
T
I
E
D
S
G
I
G
M
T
K
N
D
L
I
N
N
L
G
T
I
A
R
S
G
T
K
A
F
M
E
A
I
Q
-
A
----
S
-
G
D
I
S
M
I
G
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
D
H
V
V
V
I
S
K
N
N
D
D
E
Q
Y
V
W
E
S
A
A
G
G
S
F
T
V
T
K
D
E
T
-----
N
E
K
L
G
R
G
T
K
I
I
L
H
L
K
E
D
Q
L
E
Y
L
E
E
K
R
I
K
D
L
V
K
K
H
S
E
F
I
S
F
P
I
K
L
Y
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
HHSearch
47.49
69%
-80
* C2 *
3O0I
1
HS90A_HUMAN
A:
[37-243]
--
V
E
T
F
A
F
Q
A
E
I
A
Q
L
M
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
S
S
D
A
L
D
K
I
R
Y
E
S
L
T
D
P
S
K
-----
L
D
S
G
K
E
L
H
I
N
L
I
P
N
K
Q
D
R
T
L
T
I
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
Q
-
A
----
G
-
A
D
I
S
M
I
G
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
E
K
V
T
V
I
T
K
H
N
D
D
E
Q
Y
A
W
E
S
S
A
G
G
S
F
T
V
R
T
D
T
------
G
E
P
M
G
R
G
T
K
V
I
L
H
L
K
E
D
Q
T
E
Y
L
E
E
R
R
I
K
E
I
V
K
K
H
S
Q
F
I
G
Y
P
I
T
L
F
V
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
47.38
71%
-77
- C2 -
1UYM
1
HS90B_HUMAN
A:
[13-219]
----
T
F
A
F
Q
A
E
I
A
Q
L
M
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
E
S
L
T
D
P
S
K
-----
L
D
S
G
K
E
L
K
I
D
I
I
P
N
P
Q
E
R
T
L
T
L
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
Q
-
A
----
G
-
A
D
I
S
M
I
G
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
E
K
V
V
V
I
T
K
H
N
D
D
E
Q
Y
A
W
E
S
S
A
G
G
S
F
T
V
R
A
D
H
------
G
E
P
I
G
R
G
T
K
V
I
L
H
L
K
E
D
Q
T
E
Y
L
E
E
R
R
V
K
E
V
V
K
K
H
S
Q
F
I
G
Y
P
I
T
L
Y
L
E
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
47.38
71%
-82
- C2 -
3NMQ
1
HS90B_HUMAN
A:
[18-225]
----
T
F
A
F
Q
A
E
I
A
Q
L
M
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
Y
E
S
L
T
D
P
S
K
-----
L
D
S
G
K
E
L
K
I
D
I
I
P
N
P
Q
E
R
T
L
T
L
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
Q
-
A
----
G
-
A
D
I
S
M
I
G
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
E
K
V
V
V
I
T
K
H
N
D
D
E
Q
Y
A
W
E
S
S
A
G
G
S
F
T
V
R
A
D
H
------
G
E
P
I
G
R
G
T
K
V
I
L
H
L
K
E
D
Q
T
E
Y
L
E
E
R
R
V
K
E
V
V
K
K
H
S
Q
F
I
G
Y
P
I
T
L
Y
L
E
K
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
47.34
51%
-76
- C2 -
1QY5
2
ENPL_CANFA
A:
[4-269]
-
K
S
E
K
F
A
F
Q
A
E
V
N
R
M
M
K
L
I
I
N
S
L
Y
K
N
K
E
I
F
L
R
E
L
I
S
N
A
S
D
A
L
D
K
I
R
L
I
S
L
T
D
E
N
A
-----
L
A
G
N
E
E
L
T
V
K
I
K
C
D
K
E
K
N
L
L
H
V
T
D
T
G
V
G
M
T
R
E
E
L
V
K
N
L
G
T
I
A
K
S
G
T
S
E
F
L
N
K
M
T
-
E
A
Q
E
D
G
Q
S
T
S
E
L
I
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
K
V
I
V
T
S
K
H
N
N
D
T
Q
H
I
W
E
S
D
-
S
N
E
F
S
V
I
A
D
P
R
-----
G
N
T
L
G
R
G
T
T
I
T
L
V
L
K
E
E
A
S
D
Y
L
E
L
D
T
I
K
N
L
V
K
K
Y
S
Q
F
I
N
F
P
I
Y
V
W
S
S
K
T
-------------------------------------------------
K
T
V
W
D
W
E
L
M
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
HHSearch
47.03
69%
-80
- C2 -
1YC1
1
HS90A_HUMAN
A:
[45-252]
--
V
E
T
F
A
F
Q
A
E
I
A
Q
L
M
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
R
E
L
I
S
N
S
S
D
A
L
D
K
I
R
Y
E
T
L
T
D
P
S
K
-----
L
D
S
G
K
E
L
H
I
N
L
I
P
N
K
Q
D
R
T
L
T
I
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
A
L
Q
-
A
----
G
-
A
D
I
S
M
I
G
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
E
K
V
T
V
I
T
K
H
N
D
D
E
Q
Y
A
W
E
S
S
A
G
G
S
F
T
V
R
T
D
T
------
G
E
P
M
G
R
G
T
K
V
I
L
H
L
K
E
D
Q
T
E
Y
L
E
E
R
R
I
K
E
I
V
K
K
H
S
Q
F
I
G
Y
P
I
T
L
F
V
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
46.56
48%
-49
- C2 -
3PEH
1
?
A:
[22-281]
-
S
M
E
S
H
Q
Y
Q
T
E
V
T
R
L
M
D
I
I
V
N
S
L
Y
T
Q
K
E
V
F
L
R
E
L
I
S
N
A
A
D
A
L
E
K
I
R
F
L
S
L
S
D
E
S
V
-----
L
G
E
E
K
K
L
E
I
R
I
S
A
N
K
E
K
N
I
L
S
I
T
D
T
G
I
G
M
T
K
V
D
L
I
N
N
L
G
T
I
A
K
S
G
T
S
N
F
L
E
A
I
S
K
S
----
G
-
G
D
M
S
L
I
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
K
V
I
V
Y
T
K
N
N
D
D
E
Q
Y
I
W
E
S
T
A
D
A
K
F
T
I
Y
K
D
P
R
-----
G
A
T
L
K
R
G
T
R
I
S
L
H
L
K
E
D
A
T
N
L
L
N
D
K
K
L
M
D
L
I
S
K
Y
S
Q
F
I
Q
F
P
I
Y
L
L
H
E
N
V
Y
T
E
E
V
L
A
D
I
A
K
D
M
V
N
D
--------
P
N
Y
D
S
V
K
V
E
E
T
D
D
P
---
N
K
K
T
R
T
V
E
K
K
V
K
K
W
T
L
M
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
44.42
48%
-87
- C2 -
3IED
1
?
A:
[24-271]
--
V
E
K
Y
N
F
K
A
E
V
N
K
V
M
D
I
I
V
N
S
L
Y
T
D
K
D
V
F
L
R
E
L
I
S
N
A
S
D
A
C
D
K
K
R
I
I
L
E
N
N
K
L
I
K
D
A
EV-
N
D
I
K
K
L
I
I
K
I
K
P
D
K
E
K
K
T
L
T
I
T
D
N
G
I
G
M
D
K
S
E
L
I
N
N
L
G
T
I
A
Q
S
G
T
A
K
F
L
K
Q
I
E
-
E
----
G
K
A
D
S
N
L
I
G
Q
F
G
V
G
F
Y
S
S
F
L
V
S
N
R
V
E
V
Y
T
K
K
-
E
D
Q
I
Y
R
W
S
S
D
L
K
G
S
F
S
V
N
E
I
K
K
YDQEY--
I
K
G
S
G
T
K
I
I
L
H
L
K
E
E
C
D
E
Y
L
E
D
Y
K
L
K
E
L
I
K
K
Y
S
E
F
I
K
F
P
I
E
I
W
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------