@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00433_KS6A6_: (2014-09-07 )
MLPFAPQDEPWDREMEVFSGGGASSGEVNGLKMVDEPMEEGEADSCHDEGVVKEIPITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHVVKGAMVATYSALTHKTFQPVLEPVAASSLAQRRSMKKRTSTGL
Atome Classification :
(26 SA)
-----------------------------------------------------------------------------------------------.........10........20........30........40........50........60........-70........80.-.......90........100.......110--.--...-.-.-.120.....-.--.130........140.......150.......160....--.----..170.......180.......190-........200.....-..210.......220.......230-.-.......240.....-----.---.250.......260.......-270....----...280---..----.......--290.---......300.......310.....--.---.320.......330..---.....340.......350.--......360.....---..370.....-----.--.--380..--......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------MLPFAPQDEPWDRE
M
E
V
FSGGGASSGEVN
G
L
KMVDE
P
M
EEGEADSCHDEGV
V
K
EIPI
T
H
H
V
K
EGYEKA
D
-
P
A
Q
F
E
L
L
K
V
L
GQG-SF
G
K
V
F
L
V
R
KKTGPD
A
G
Q
L
Y
A
M
K
V
L
K
K
A
S
L
--
K
--
V
R
D
-
R
-
V
-
R
T
K
MER
D
I
L
-
V
--EV-NH
P
F
I
V
K
L
H
Y
A
FQTE
G
K
L
Y
L
I
L
D
F
LRG
G
D
V
F
T
R
L
S
K
--
E
----VLF
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
Q
-
L
G
I
V
Y
RDLKPE
N
I
L
LD-EIG
H
I
K
L
T
DFGLSK
E
S
V
D
Q
E
K
K
A
Y
--
S
-
F
CG
T
V
E
Y
M
A
P
E
V
V
NR-----R---GHSQSA
D
W
W
S
Y
G
V
L
M
F
E
M
L
TG-TLPFQGK----DR
N
E
-----
T
M
----
N
M
I
L
K
AK--LGM
P
---
Q
F
L
S
A
E
A
Q
S
L
L
R
M
L
F
KR
N
P
A
NRL
G
--
S
---
E
G
V
E
E
I
K
R
H
L
F
FANI
D
---
W
D
K
L
Y
K
R
EVQPPFKPASGK--PDD
T
F
CFDPEFTAK---TPKDSPGLPA-----S--A--
N
-
A
H
Q
--
L
F
K
G
F
S
F
V
A
T
S
I
AEEYKITPITSA
N
V
L
P
I
V
Q
INGNAAQF
G
E
V
Y
E
L
K
E
D
IGVG
S
Y
S
V
C
K
R
C
I
H
ATTN
M
E
F
A
V
K
I
IDKSKRD
P
S
E
E
I
E
I
L
M
R
YGQHP
N
I
I
T
L
K
DVFDDG
R
Y
V
Y
L
V
T
D
L
MK
G
G
E
L
L
D
R
I
L
K
Q
K
CFSEREA
S
D
I
L
Y
V
I
S
K
T
V
D
Y
L
HCQGVVHRDLKPS
N
I
L
Y
MDESASAD
S
I
R
I
CDF
G
F
A
K
Q
LRGEN
G
L
L
L
TPCYTANFV
A
P
E
V
L
M
QQGY
D
A
A
C
D
I
W
S
L
G
V
L
F
Y
T
M
L
AGYTPFANGPND
T
P
E
E
I
L
L
RIGN
G
K
F
S
LSGGNWDNI
S
D
G
A
K
D
L
L
S
H
M
LHMDPHQR
Y
T
A
E
Q
I
L
K
H
S
WI
T
H
RDQLPNDQPKR
N
D
V
S
H
V
V
K
G
A
M
V
A
T
Y
S
A
L
T
H
K
T
F
Q
P
V
L
E
P
V
A
A
S
S
L
A
Q
R
R
S
M
K
KRTSTGL
2
PsiBlast_PDB
80.42
87%
-91
- C1 -
4NW5
1
?
A:
[15-323]
------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
-
R
-
V
-
R
T
K
M
E
R
D
I
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
I
D
H
E
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------
T
F
Y
F
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.36
87%
-92
- C1 -
4NW6
1
?
A:
[15-323]
------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
-
R
-
V
-
R
T
K
M
E
R
D
I
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
I
D
H
E
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------
T
F
Y
F
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
75.71
89%
-108
- C1 -
3UBD
1
KS6A3_MOUSE
A:
[7-304]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
-
R
-
V
-------
D
I
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
-----
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.09
88%
-107
- C1 -
4GUE
1
KS6A3_MOUSE
A:
[7-305]
---------------------------------------------------------------------------------------------------------------------------------------------------
K
E
I
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
-
R
-
V
---------
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
-----
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
74.99
88%
-107
- C1 -
3G51
1
KS6A3_MOUSE
A:
[5-304]
--------------------------------------------------------------------------------------------------------------------------------------------------
I
K
E
I
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
------------
I
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
I
--------------
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.51
88%
-106
- C1 -
4EL9
1
KS6A3_MOUSE
A:
[8-305]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
I
T
H
H
V
K
E
G
H
E
K
A
D
-
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
R
D
-
R
-
V
-
R
-----
D
I
L
-
V
--
E
V
-
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
---
E
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
--
A
GP-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
71.94
85%
-112
- C1 -
2Z7S
1
KS6A1_HUMAN
A:
[24-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
-
P
S
H
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
K
------------------------
I
L
-
A
--
D
V
-
N
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
Q
---
G
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
L
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
--
S
GP-
D
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
71.38
53%
-91
- C1 -
4L46
1
KS6B1_HUMAN
A:
[9-346]
------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
G
P
E
K
I
R
-
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
N
--
A
K
D
-
T
-
A
-
H
T
K
A
E
R
N
I
L
-
E
--
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
----
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
D
----
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
R
-----
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
T
G
E
----
N
R
K
K
-----
T
I
----
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
--
A
GP-
G
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
-----
E
E
D
V
S
Q
F
D
S
K
F
T
R
Q
---
T
P
V
----------------------
Q
--
V
F
L
G
F
T
Y
V
A
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
70.01
53%
-90
- C1 -
4L43
1
KS6B1_HUMAN
A:
[10-346]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
P
E
K
I
R
-
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
N
--
A
K
D
-
T
-
A
-
H
T
K
A
E
R
N
I
L
-
E
--
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
----
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
S
--------------
G
T
I
E
Y
M
A
P
E
I
L
M
R
-----
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
T
G
E
----
N
R
K
K
-----
T
I
----
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
--
A
GP-
G
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
--
E
E
D
V
S
Q
F
D
S
K
F
T
R
Q
---
T
P
V
------------------
S
-
A
N
Q
--
V
F
L
G
F
A
Y
V
A
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
69.16
53%
-85
- C1 -
4L44
1
KS6B1_HUMAN
A:
[10-346]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
P
E
K
I
R
-
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
N
--
A
K
D
-
T
-
A
-
H
T
K
A
E
R
N
I
L
-
E
--
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
----
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
-----
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
R
-----
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
T
G
E
----
N
R
K
K
-----
T
I
----
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
--
A
GP-
G
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
--
E
E
D
V
S
Q
-
D
S
K
F
T
R
Q
---
T
--------------
S
--
E
--
S
-
A
N
Q
--
V
F
L
G
F
A
Y
V
A
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
68.65
85%
-106
- C1 -
2Z7R
1
KS6A1_HUMAN
A:
[21-308]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
E
K
A
D
-
P
S
H
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
K
K
A
T
L
--
K
--
V
--------------
I
L
-
A
--
D
V
-
N
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
Q
---
G
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
L
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
--
S
GP-
D
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
67.93
85%
-113
- C1 -
2Z7Q
1
KS6A1_HUMAN
A:
[24-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
-
P
S
H
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
-------------------------
I
L
-
A
--
D
V
-
N
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
----
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
R
-----
Q
---
G
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
Q
G
K
----
D
R
K
E
-----
T
M
----
T
L
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
--
S
GP-
D
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
65.98
53%
-96
- C1 -
4L42
1
KS6B1_HUMAN
A:
[13-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
I
R
-
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
--
V
RN
A
K
D
-
T
-
A
-
H
T
K
A
E
R
N
I
L
-
E
--
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
----
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
D
G
T
V
T
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
R
-----
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
T
G
E
----
N
R
K
K
-----
T
I
----
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
--
A
GP-
G
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
-------------------------------------------------
E
--
M
F
R
D
F
E
Y
I
A
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
62.75
30%
-67
- C1 -
2ACX
1
GRK6_HUMAN
A:
[14-532]
KARKGKSKK
W
R
Q
M
L
QFPHISQC
E
E
L
R
L
S
LERD
Y
H
S
L
C
ERN
P
I
G
R
L
L
F
R
E
F
C
A
T
R
P
E
L
S
R
C
V
A
F
L
D
G
V
A
E
Y
E
V
TPDDK
R
K
A
C
G
R
N
L
T
Q
N
FLSHTGP
D
L
I
P
E
V
P
R
Q
L
V
T
N
C
T
Q
R
L
E
Q
G
P
C
K
D
L
F
Q
E
L
T
R
L
T
H
E
Y
L
S
V
A
P
F
A
D
Y
L
D
S
I
Y
F
N
R
F
L
Q
W
K
W
L
E
R
--
Q
P
V
T
-
K
N
T
F
R
Q
Y
R
V
L
G
K
G
-
G
F
G
E
V
C
A
C
Q
V
R
---
A
T
G
K
M
Y
A
C
K
K
L
E
K
K
R
I
--
K
--
K
R
K
G
E
-
A
-
M
A
L
N
E
K
Q
I
L
-
E
--
K
V
-
N
S
R
F
V
V
S
L
A
Y
A
Y
E
T
K
D
A
L
C
L
V
L
T
L
M
N
G
G
D
L
K
F
H
I
Y
H
MG
Q
----
A
G
F
P
E
A
R
A
V
F
Y
A
A
E
I
C
C
G
L
E
D
L
H
-
R
-
E
R
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
D
H
G
H
I
R
I
S
D
L
G
L
A
V
H
-
V
P
E
G
Q
T
I
K
--
G
-
R
V
G
T
V
G
Y
M
A
P
E
V
V
K
N
-----
E
---
R
Y
T
F
S
P
D
W
W
A
L
G
C
L
L
Y
E
M
I
A
G
-
Q
S
P
F
Q
Q
R
K
K
K
I
K
R
E
E
-----
V
E
----
R
L
V
K
E
V
P
--
E
E
Y
S
---
E
R
F
S
P
Q
A
R
S
L
C
S
Q
L
L
C
K
D
P
A
E
R
L
G
CR
G
---
G
S
A
R
E
V
K
E
H
P
L
F
K
K
L
N
---
F
K
R
L
G
A
G
M
L
E
P
P
F
K
P
-
D
P
Q
--
A
I
Y
C
E
P
T
D
Q
D
F
Y
Q
K
---
F
A
T
G
S
V
P
I
P
W
-----
Q
--
N
--
E
-
M
V
E
T
E
C
F
Q
E
L
N
V
F
G
L
D
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
60.53
40%
-83
- C1 -
3PFQ
1
KPCB_RAT
A:
[341-669]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
F
N
F
L
M
V
L
G
K
G
-
S
F
G
K
V
M
L
S
E
R
---
K
G
T
D
E
L
Y
A
V
K
I
L
K
K
D
V
V
--
I
--
Q
D
D
-
D
-
V
E
C
T
M
V
E
K
R
V
L
-
A
--
L
P
G
K
P
P
F
L
T
Q
L
H
S
C
F
Q
T
M
D
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Y
H
I
Q
Q
--
V
----
G
R
F
K
E
P
H
A
V
F
Y
A
A
E
I
A
I
G
L
F
F
L
Q
-
S
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
M
L
D
-
S
E
G
H
I
K
I
A
D
F
G
M
C
K
E
N
I
W
D
G
V
T
T
K
--
T
-
F
C
G
T
P
D
Y
I
A
P
E
I
I
A
Y
-----
Q
---
P
Y
G
K
S
V
D
W
W
A
F
G
V
L
L
Y
E
M
L
A
G
-
Q
A
P
F
E
G
E
----
D
E
D
E
-----
L
F
----
Q
S
I
M
E
H
N
--
V
A
Y
P
---
K
S
M
S
K
E
A
V
A
I
C
K
G
L
M
T
K
H
P
G
K
R
L
G
--
C
GP-
E
G
E
R
D
I
K
E
H
A
F
F
R
Y
I
D
---
W
E
K
L
E
R
K
E
I
Q
P
P
Y
K
P
K
A
S
G
--
R
-
N
A
E
N
F
D
R
F
F
T
R
H
---
P
P
V
L
T
P
P
D
Q
E
-----
V
I
-
R
--
N
I
D
Q
S
--
E
F
E
G
F
S
F
V
N
S
E
F
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
59.65
43%
-89
* C1 *
4GV1
5
AKT1_HUMAN
A:
[6-337]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
---
K
A
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
--
V
--
A
K
D
-
E
-
V
A
H
T
L
T
E
N
R
V
L
-
Q
--
N
S
-
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
----
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
-
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
D
-----
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
Y
N
Q
----
D
H
E
K
-----
L
F
----
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
--
G
GS-
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
--
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
---
M
I
T
I
T
P
----SMECV
D
--
S
--
E
-
R
R
P
--
H
F
P
Q
F
D
Y
S
A
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
58.89
45%
-104
- C1 -
4EJN
3
AKT1_HUMAN
A:
[147-438]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
---
K
A
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
--
V
-----------------
V
L
-
Q
--
N
S
-
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
----
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
-
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
-----
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
D
-----
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
Y
N
Q
----
D
H
E
K
-----
L
F
----
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
--
G
GS-
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
--
E
T
D
T
R
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
57.36
39%
-84
- C1 -
4AW2
3
MRCKA_RAT
A:
[72-411]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-
R
E
D
F
E
I
L
K
V
I
G
R
G
-
A
F
G
E
V
A
V
V
K
L
---
K
N
A
D
K
V
F
A
M
K
I
L
N
K
W
E
M
--
L
--
K
R
A
E
T
-
A
-
C
F
R
E
E
R
D
V
L
-
V
--
N
G
-
D
S
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
-
E
----
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
-
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
-
M
N
G
H
I
R
L
A
D
F
G
S
C
L
K
L
M
E
D
G
T
V
Q
S
--
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
GGK
G
---
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
-
E
T
P
F
Y
A
E
----
S
L
V
E
-----
T
Y
----
G
K
I
M
N
H
K
ER
F
Q
F
P
TQV
T
D
V
S
E
N
A
K
D
L
I
R
R
L
I
C
-
S
R
E
H
R
L
G
--
Q
---
N
G
I
E
D
F
K
K
H
P
F
F
S
G
I
D
---
W
D
N
I
--
R
N
C
E
A
P
Y
I
P
E
V
S
S
--
P
T
D
T
S
N
F
D
V
D
-------------------------
S
--
G
-
H
H
L
--
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
57.19
38%
-83
- C1 -
4DC2
2
KPCI_MOUSE
A:
[50-387]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
L
Q
D
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
L
---
K
K
T
D
R
I
Y
A
M
R
V
V
K
K
E
L
V
--
N
--------
I
D
W
V
Q
T
E
K
H
V
F
-
E
--
Q
A
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
----
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
-
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
R
P
G
D
T
T
S
--
T
-
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
G
-----
E
---
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
D
I
V
----
G
S
--NT
E
D
Y
L
F
----
Q
V
I
L
E
K
Q
--
I
R
I
P
---
R
S
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
R
L
G
--
C
HPQ
T
G
F
A
D
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
--
E
F
G
L
D
N
F
D
S
Q
F
T
N
E
---
P
V
Q
L
T
P
D
D
D
D
-----
I
V
R
K
--
I
-
D
Q
S
--
E
F
E
G
F
E
Y
I
N
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
55.10
32%
-82
- C1 -
3C4Z
1
RK_BOVIN
A:
[182-513]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
-
E
D
W
F
L
D
F
R
V
L
G
R
G
-
G
F
G
E
V
F
A
C
Q
M
---
K
A
T
G
K
L
Y
A
C
K
K
L
N
K
K
R
L
--
K
--
K
R
K
-
G
-
Y
Q
G
A
M
V
E
K
K
I
L
-
A
--
K
V
-
H
S
R
F
I
V
S
L
A
Y
A
F
E
T
K
T
D
L
C
L
V
M
T
I
M
N
G
G
D
I
R
Y
H
I
Y
N
--
V
DED
N
P
G
F
Q
E
P
R
A
I
F
Y
T
A
Q
I
V
S
G
L
E
H
L
H
-
Q
-
R
N
I
I
Y
R
D
L
K
P
E
N
V
L
L
D
-
D
D
G
N
V
R
I
S
D
L
G
L
A
V
E
L
K
A
G
Q
T
K
T
K
--
G
-
Y
A
G
T
P
G
F
M
A
P
E
L
L
L
G
-----
E
---
E
Y
D
F
S
V
D
Y
F
A
L
G
V
T
L
Y
E
M
I
A
A
-
R
G
P
F
R
A
R
----
G
E
K
V
-----
E
N
K
E
L
K
Q
R
V
L
E
Q
A
--
V
T
Y
P
---
D
K
F
S
P
A
S
K
D
F
C
E
A
L
L
Q
K
D
P
E
K
R
L
G
--
F
RD-
G
S
C
D
G
L
R
T
H
P
L
F
R
D
I
S
---
W
R
Q
L
E
A
G
M
L
T
P
P
F
V
P
D
S
R
T
VY
A
K
N
----
G
-
A
F
S
-----------
G
V
A
F
-----
E
--
K
--
A
-
D
T
E
--
F
F
Q
E
F
A
S
G
T
C
P
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
53.65
40%
-85
- C1 -
3TXO
1
KPCL_HUMAN
A:
[23-349]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
F
E
F
I
R
V
L
G
K
G
-
S
F
G
K
V
M
L
A
R
V
---
K
E
T
G
D
L
Y
A
V
K
V
L
K
K
D
V
I
--
L
--
Q
D
D
-
D
-
V
E
C
T
M
T
E
K
R
I
L
-
S
--
L
A
R
N
H
P
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
Q
K
--
S
----
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
-
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
H
E
G
H
C
K
L
A
D
F
G
M
C
K
E
G
I
C
------------
G
T
P
D
Y
I
A
P
E
I
L
Q
E
-----
M
---
L
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
-
H
A
P
F
E
A
E
----
N
E
D
D
-----
L
F
----
E
A
I
L
N
D
E
--
V
V
Y
P
---
T
W
L
H
E
D
A
T
G
I
L
K
S
F
M
T
K
N
P
T
M
R
L
G
--
S
LTQ
G
G
E
H
A
I
L
R
H
P
F
F
K
E
I
D
---
W
A
Q
L
N
H
R
Q
I
E
P
P
F
R
P
R
I
K
S
--
R
E
D
V
S
N
F
D
P
D
F
I
K
E
---
E
P
V
L
T
P
I
D
E
G
-----
H
--
L
PM
I
-
N
Q
D
--
E
F
R
N
F
E
Y
V
S
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
53.27
39%
-84
- C1 -
1RDQ
4
KAPCA_MOUSE
E:
[39-334]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-
L
D
Q
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
K
---
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
--
V
--
K
L
K
-
Q
I
E
-
H
T
L
N
E
K
R
I
L
-
Q
--
A
V
-
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
----
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
---
G
R
T
W
--
T
-
L
C
G
T
P
E
A
L
A
P
E
I
I
L
S
-----
K
---
G
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
F
A
D
----
Q
P
I
Q
-----
I
Y
----
E
K
I
V
S
G
K
--
V
R
F
P
---
S
H
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
--
N
LK-
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
--
P
G
D
T
S
N
F
D
D
-
Y
E
E
E
---
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
52.76
41%
-90
- C1 -
1XJD
1
A:
[17-335]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
F
I
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
F
---
K
K
T
N
Q
F
F
A
I
K
A
L
K
K
D
V
V
--
L
--
M
D
D
-
D
-
V
E
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W
E
H
P
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
----
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
-
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
M
C
K
E
N
M
L
G
D
A
K
T
N
--
T
-
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
G
-----
Q
---
K
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
H
G
Q
----
D
E
E
E
-----
L
F
----
H
S
I
R
M
D
N
--
P
F
Y
P
---
R
W
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
R
L
G
--
V
---
R
--
G
D
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
---------------------------------------------------
Q
N
--
M
F
R
N
F
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
52.35
43%
-105
- C1 -
2R5T
1
SGK1_HUMAN
A:
[35-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
-
P
S
D
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
H
---
K
A
E
E
V
F
Y
A
V
K
V
L
Q
K
K
A
I
--
L
-----------------
V
L
L
K
--
N
V
-
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
----
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
-
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
S
Q
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
T
S
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
K
-----
Q
---
P
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
-
L
P
P
F
Y
S
R
----
N
T
A
E
-----
M
Y
----
D
N
I
L
N
K
P
--
L
Q
L
K
---
P
N
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
--
A
K--
D
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
48.47
54%
-98
- C1 -
3A60
1
KS6B1_HUMAN
A:
[13-299]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
-
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
K
A
M
----------------
K
A
E
R
N
I
L
-
E
--
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
----
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
----------------
T
I
E
Y
M
A
P
E
I
L
M
R
-----
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
T
G
E
----
N
R
K
K
-----
T
I
----
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
--
A
GP-
G
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
46.50
36%
-81
- C1 -
1CDK
3
KAPCA_PIG
A:
[8-350]
-------------------------------------------------------------------------------------------------------------------------------
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
A
K
E
D
F
L
K
K
W
E
N
P
A
Q
N
T
A
------H
L
D
Q
F
E
R
I
K
T
L
G
T
-G
S
F
G
R
V
M
L
V
K
H
K
--
E
T
G
-
N
H
F
A
M
K
I
L
D
K
Q
K
V
--
V
K
-
L
K
Q
-
I
-
E
-
H
T
L
N
E
K
R
I
L
-
Q
A
V---
N
F
P
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
I
------
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
--
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q-
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
-
K
--
G
--
R
TW
T
-
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
S
------KGY--
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y-
P
P
F
F
A
D
----
Q
P
I
Q
-----
I
Y
----
E
K
I
V
S
G
K
--
V
R
F
P
S---
H
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
--
N
LK-
D
G
V
N
D
I
K
N
H
K
W
F
A
---TT
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
--
P
G
D
T
S
N
F
D
D
Y
E
E
E
E
I
R
V
S
I
-------------
N
--
E
--
K
-
C
G
K
--
E
F
S
E
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------