@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00693_KITH_H: (2014-09-14 )
MASHAGQQHAPAFGQAARASGPTDGRAASRPSHRQGASEARGDPELPTLLRVYIDGPHGVGKTTTSAQLMEALGPRDNIVYVPEPMTYWQVLGASETLTNIYNTQHRLDRGEISAGEAAVVMTSAQITMSTPYAATDAVLAPHIGGEAVGPQAPPPALTLVFDRHPIASLLCYPAARYLMGSMTPQAVLAFVALMPPTAPGTNLVLGVLPEAEHADRLARRQRPGERLDLAMLSAIRRVYDLLANTVRYLQRGGRWREDWGRLTGVAAATPRPDPEDGAGSLPRIEDTLFALFRVPELLAPNGDLYHIFAWVLDVLADRLLPMHLFVLDYDQSPVGCRDALLRLTAGMIPTRVTTAGSIAEIRDLARTFAREVGGV
Atome Classification :
(22 SA)
.........10........20........30........40........50........60.....-...70........80........90........100.......110.......120.......130.......140.......150--.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270----.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MASHAGQQHAPAFGQAARASGPTDGRAASRPSHRQGASEARGDPE
L
P
T
L
L
R
V
Y
IDGPHGVGKT
T
T
S
-
A
Q
L
M
E
A
LGPRD
N
I
V
YVPEP
M
T
Y
W
Q
VLGA
S
E
T
L
T
N
I
Y
N
T
Q
HRLDRGEISAG
E
A
A
V
V
M
T
S
A
Q
I
T
MSTPYAATDAVLAPHIGGEAVGPQ--APP
P
A
L
T
L
V
FDRH
P
I
A
S
L
L
C
Y
P
A
A
R
Y
L
MGSM
T
P
Q
A
V
L
A
F
V
A
LMPPTAPGT
N
L
V
L
G
VLPE
A
E
H
A
D
R
L
A
R
RQRPG
E
R
L
D
L
A
M
L
S
A
I
R
R
V
Y
D
L
L
A
N
T
V
R
Y
L
Q
RGGR
W
R
E
D
WGRLTGVAAATPR----PDPEDGAGSLP
R
I
E
D
T
L
F
A
L
F
R
V
P
E
L
LAPNG
D
L
Y
H
I
F
A
W
V
L
D
V
L
A
D
RLL
P
M
H
L
F
V
L
DYDQSPV
G
C
R
D
A
L
L
R
L
T
AGMIPTRVTTAG
S
I
A
E
I
R
D
L
A
R
T
F
A
R
E
VGGV
32
PsiBlast_CBE
97.77
77%
-128
- C5 -
4IVQ
1
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
--
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
-------------
P
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
30
PsiBlast_CBE
97.71
77%
-131
- C5 -
4IVR
1
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
---
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
----------------
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
9
PsiBlast_PDB
97.57
77%
-135
- C5 -
3F0T
1
KITH_HHV11
A:
[1-329]
--------------------------------------------
K
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
46
PsiBlast_CBE
97.49
77%
-129
- C5 -
1E2M
1
KITH_HHV11
B:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
------
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
------
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
-------------
P
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
31
PsiBlast_CBE
97.32
77%
-132
- C5 -
4IVQ
1
KITH_HHV11
B:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
25
PsiBlast_CBE
97.26
76%
-128
- C5 -
1P7C
1
KITH_HHV11
B:
[13-340]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
S
H
--
A
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
-----------------
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
20
PsiBlast_PDB
97.17
77%
-132
- C5 -
1E2M
1
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
-----
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
------
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
28
PsiBlast_CBE
97.16
77%
-125
- C5 -
3F0T
1
KITH_HHV11
B:
[2-329]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
--
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
-------------
P
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
29
PsiBlast_CBE
97.01
77%
-134
- C5 -
4IVR
1
KITH_HHV11
B:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
---------------------
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
52
PsiBlast_CBE
96.89
77%
-125
- C5 -
1E2J
1
KITH_HHV11
B:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
N
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
-----
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
------
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
T
A
V
P
----------
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
48
PsiBlast_CBE
96.77
77%
-124
- C5 -
1E2I
2
KITH_HHV11
B:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
---
H
--
A
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
----
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
-------------
P
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
6
PsiBlast_PDB
96.14
76%
-134
- C5 -
2VTK
2
KITH_HHV11
A:
[13-340]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
-----
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
21
PsiBlast_CBE
96.06
74%
-127
- C5 -
1OF1
1
KITH_HHV11
B:
[46-373]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
-------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
---
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
T
------------
P
Q
S
N
A
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
5
PsiBlast_PDB
96.06
76%
-130
- C5 -
1VTK
2
KITH_HHV11
A:
[13-340]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
-----
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
8
PsiBlast_PDB
96.01
77%
-133
- C5 -
1KI6
1
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
-------
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
--------
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
--------------------
A
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
53
PsiBlast_CBE
95.73
77%
-130
- C5 -
1E2J
1
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
-----
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
N
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
-----
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
19
PsiBlast_PDB
95.72
77%
-134
- C5 -
1E2I
2
KITH_HHV11
A:
[1-328]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
--------------
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
T
-----------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
4
PsiBlast_PDB
94.80
76%
-134
- C5 -
1P7C
1
KITH_HHV11
A:
[12-338]
--------------------------------------------
K
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
----
D
I
V
Y
V
P
E
P
----
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
------
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
G
------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
----
7
PsiBlast_PDB
94.69
76%
-132
- C5 -
3VTK
2
KITH_HHV11
A:
[13-340]
---------------------------------------------
M
P
T
L
L
R
V
Y
I
D
G
P
H
G
M
G
K
T
T
T
T
--
Q
L
L
V
A
L
G
S
R
D
D
I
V
Y
V
P
E
P
M
T
Y
W
R
V
L
G
A
S
E
T
I
A
N
I
Y
T
T
Q
H
R
L
D
Q
G
E
I
S
A
G
D
A
A
V
V
M
T
S
A
Q
I
T
M
G
M
P
Y
A
V
T
D
A
V
L
A
P
H
I
G
G
E
A
G
S
-----
P
P
P
A
L
T
L
I
F
D
R
H
P
I
A
A
L
L
C
Y
P
A
A
R
Y
L
M
G
S
M
T
P
Q
A
V
L
A
F
V
A
L
I
P
P
T
L
P
G
T
N
I
V
L
G
A
L
P
E
D
R
H
I
D
R
L
A
K
R
Q
R
P
G
E
R
L
D
L
A
M
L
A
A
I
R
R
V
Y
G
L
L
A
N
T
V
R
Y
L
Q
C
G
G
S
W
R
E
D
W
G
Q
L
S
-------------------
G
P
R
P
H
I
G
D
T
L
F
T
L
F
R
A
P
E
L
L
A
P
N
G
D
L
Y
N
V
F
A
W
A
L
D
V
L
A
K
R
L
R
S
M
H
V
F
I
L
D
Y
D
Q
S
P
A
G
C
R
D
A
L
L
Q
L
T
S
G
M
V
Q
T
H
V
T
T
P
G
S
I
P
T
I
C
D
L
A
R
T
F
A
R
E
M
G
--
67
HHSearch
79.75
36%
-113
- C5 -
1P6X
1
KITH_EHV4
A:
[2-333]
-------------------------------------------
S
H
M
V
T
I
V
R
I
Y
L
D
G
V
Y
G
I
G
K
S
T
T
G
-
R
V
M
A
S
A
A
S
G
G
S
P
T
L
Y
F
P
E
P
M
A
Y
W
R
T
L
F
E
T
D
V
I
S
G
I
Y
D
T
Q
N
R
K
Q
Q
G
N
L
A
V
D
D
A
A
L
I
T
A
H
Y
Q
S
R
F
T
T
P
Y
L
I
L
H
D
H
T
C
T
L
F
G
G
N
S
L
Q
R
---
G
T
Q
P
D
L
T
L
V
F
D
R
H
P
V
A
S
T
V
C
F
P
A
A
R
Y
L
L
G
D
M
S
M
C
A
L
M
A
M
V
A
T
L
P
R
E
P
Q
G
G
N
I
V
V
T
T
L
N
V
E
E
H
I
R
R
L
R
T
R
A
R
I
G
E
Q
I
D
I
T
L
I
A
T
L
R
N
V
Y
F
M
L
V
N
T
C
H
F
L
R
S
G
R
V
W
R
D
G
W
G
E
L
P
T
S
C
G
A
Y
K
H
R
A
T
Q
M
D
A
F
Q
E
R
-
V
S
P
E
L
G
D
T
L
F
A
L
F
K
T
Q
E
L
L
D
D
R
G
V
I
L
E
V
H
A
W
A
L
D
A
L
M
L
K
L
R
N
L
N
V
F
S
A
D
L
S
G
T
P
R
Q
C
A
A
V
V
E
S
L
L
P
L
M
S
S
T
-
L
S
D
F
D
S
A
S
A
L
E
R
A
A
R
T
F
N
A
E
M
G
--
66
HHSearch
73.46
30%
-115
- C5 -
1OSN
2
KITH_VZVO
A:
[10-338]
----------------------------------------------
M
G
V
L
R
I
Y
L
D
G
A
Y
G
I
G
K
T
T
A
A
E
E
F
L
H
H
F
A
I
T
P
N
R
I
L
L
I
G
E
P
L
S
Y
W
R
N
L
A
G
E
D
A
I
C
G
I
Y
G
T
Q
T
R
R
L
N
G
D
V
S
P
E
D
A
Q
R
L
T
A
H
F
Q
S
L
F
C
S
P
H
A
I
M
H
A
K
I
S
A
L
M
D
T
S
T
S
D
L
V
QV
N
K
E
P
Y
K
I
M
L
S
D
R
H
P
I
A
S
T
I
C
F
P
L
S
R
Y
L
V
G
D
M
S
P
A
A
L
P
G
L
L
F
T
L
P
A
E
P
P
G
T
N
L
V
V
C
T
V
S
L
P
S
H
L
S
R
V
S
------
E
T
V
N
L
P
F
V
M
V
L
R
N
V
Y
I
M
L
I
N
T
I
I
F
L
K
T
N
-
N
W
H
A
G
W
N
T
L
S
F
C
N
D
V
F
K
Q
K
L
Q
-
K
S
E
C
I
K
L
R
E
V
P
G
I
E
D
T
L
F
A
V
L
K
L
P
E
L
C
G
E
F
G
N
I
L
P
L
W
A
W
G
M
E
T
L
S
N
C
L
R
S
M
S
P
F
V
L
S
L
E
Q
T
P
Q
H
A
A
Q
E
L
K
T
L
L
P
Q
M
T
P
A
-
N
M
S
S
G
A
W
N
I
L
K
E
L
V
N
A
V
Q
D
-----
77
HHSearch
10.87
43%
104
- C5 -
2CDN
2
KAD_MYCTU
A:
[18-45]
----------------------------------------------
G
S
H
M
R
V
L
L
L
G
P
P
G
A
G
K
G
T
Q
A
-
V
K
L
A
E
K
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------