@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF01487_AROD_E: (2014-09-25 )
MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
Atome Classification :
(23 SA)
..-.......10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
-
T
V
T
V
K
D
L
V
IGTG
A
P
K
I
I
V
S
L
M
A
K
D
I
A
S
V
K
S
E
A
L
A
YREAD
F
D
I
L
E
W
R
V
D
H
YA
D
L
S
N
V
E
S
V
M
A
A
A
K
I
L
R
E
TMPEK
P
L
L
F
T
FRSAKEGGEQAIST
E
A
Y
I
A
L
N
R
A
A
IDSGL
V
D
M
I
D
L
E
L
FTG
D
D
Q
V
K
E
T
V
A
YAHA
H
D
V
K
V
V
MSNHDFHKTP
E
A
E
E
I
I
A
R
L
R
K
M
Q
S
FDADI
P
K
I
A
LMPQS
T
S
D
V
L
T
L
L
A
A
T
L
E
M
Q
E
Q
YADR
P
I
I
T
M
S
M
A
K
T
G
V
I
S
R
L
A
G
E
V
FGSAATFGAVKKASAPG
Q
I
S
V
N
D
L
R
T
V
L
T
I
LHQA
43
Fugue
97.06
76%
-107
- C4 -
1QFE
1
AROD_SALTI
A:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
20
PsiBlast_CBE
97.04
80%
-104
- C4 -
3S42
5
AROD_SALTY
B:
[25-276]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
24
PsiBlast_CBE
96.64
80%
-109
- C4 -
4GFS
1
AROD_SALTY
B:
[4-255]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
---
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
41
PsiBlast_CBE
96.38
76%
-103
- C4 -
1L9W
1
AROD_SALTI
C:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
8
PsiBlast_PDB
96.21
80%
-103
- C4 -
4GUJ
1
AROD_SALTY
A:
[5-255]
-
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
39
PsiBlast_CBE
96.17
76%
-105
- C4 -
1QFE
1
AROD_SALTI
B:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
22
PsiBlast_CBE
96.12
80%
-103
- C4 -
4GUJ
1
AROD_SALTY
B:
[5-255]
-
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
7
PsiBlast_PDB
96.03
80%
-104
- C4 -
4GUI
1
AROD_SALTY
A:
[5-255]
-
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
37
PsiBlast_CBE
95.71
79%
-102
- C4 -
4IUO
1
AROD_SALTY
B:
[25-276]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
16
PsiBlast_PDB
95.71
76%
-102
- C4 -
1L9W
1
AROD_SALTI
A:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
38
PsiBlast_CBE
95.53
79%
-104
- C4 -
3NNT
1
AROD_SALTY
B:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
23
PsiBlast_CBE
95.50
80%
-102
- C4 -
4GUI
1
AROD_SALTY
B:
[5-255]
-
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
34
PsiBlast_CBE
95.49
79%
-113
- C4 -
4GUG
1
AROD_SALTY
B:
[27-275]
---
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
----
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
42
PsiBlast_CBE
95.46
76%
-105
- C4 -
1L9W
1
AROD_SALTI
B:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
40
PsiBlast_CBE
95.44
76%
-102
- C4 -
1L9W
1
AROD_SALTI
D:
[1-252]
M
K
-
T
V
T
V
K
N
L
I
I
G
E
G
M
P
K
I
I
V
S
L
M
G
R
D
I
N
S
V
K
A
E
A
L
A
Y
R
E
A
T
F
D
I
L
E
W
R
V
D
H
F
M
D
I
A
S
T
Q
S
V
L
T
A
A
R
V
I
R
D
A
M
P
D
I
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
A
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
N
V
Y
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
2
PsiBlast_PDB
94.81
80%
-100
- C4 -
3LB0
2
AROD_SALTY
A:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
33
PsiBlast_CBE
94.80
79%
-102
- C4 -
4GUH
1
AROD_SALTY
B:
[25-276]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
13
PsiBlast_PDB
94.64
79%
-103
- C4 -
3NNT
1
AROD_SALTY
A:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
14
PsiBlast_PDB
94.62
79%
-103
- C4 -
4IUO
1
AROD_SALTY
A:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
10
PsiBlast_PDB
94.36
79%
-106
- C4 -
4GUG
1
AROD_SALTY
A:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
----
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
11
PsiBlast_PDB
93.96
79%
-104
- C4 -
4GUH
1
AROD_SALTY
A:
[25-275]
M
K
-
T
V
T
V
R
D
L
V
V
G
E
G
A
P
K
I
I
V
S
L
M
G
K
T
I
T
D
V
K
S
E
A
L
A
Y
R
E
A
D
F
D
I
L
E
W
R
V
D
H
F
A
N
V
T
T
A
E
S
V
L
E
A
A
G
A
I
R
E
I
I
T
D
K
P
L
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
A
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
54
HHSearch
89.85
54%
-99
* C4 *
4H3D
3
AROD_CLOD6
A:
[4-256]
M
K
R
K
V
Q
V
K
N
I
T
I
G
E
G
R
P
K
I
C
V
P
I
I
G
K
N
K
K
D
I
I
K
E
A
K
E
L
K
D
A
C
L
D
I
I
E
W
R
V
D
F
F
E
N
V
E
N
I
K
E
V
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
P
L
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
I
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
K
K
E
V
K
V
I
I
S
N
H
D
F
N
K
T
P
K
K
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
---
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
18
PsiBlast_PDB
87.82
52%
-96
- C4 -
3JS3
1
AROD_CLOD6
A:
[6-256]
-
R
-
K
V
Q
V
K
N
I
T
I
G
E
G
R
P
K
I
C
V
P
I
I
G
K
N
K
K
D
I
I
K
E
A
K
E
L
K
D
A
C
L
D
I
I
E
W
R
V
D
F
F
E
N
V
E
N
I
K
E
V
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
P
L
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
I
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
K
K
E
V
K
V
I
I
S
N
H
D
F
N
K
T
P
K
K
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S