@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF12549_TY3H_HUMAN: (2014-10-18 )
MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGAPGPSLTGSPWPGTAAPAASYTPTPRSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
Atome Classification :
(12 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPTPDATT
P
Q
A
K
G
F
R
R
A
V
S
E
L
D
A
KQA
E
A
I
M
V
RGQGAPGPSLTGSPWPGTAAPAASYTPTPRS
P
R
F
I
G
R
R
Q
S
L
I
E
D
A
R
K
E
R
E
A
A
V
A
A
A
A
AAVPSEPGDP
L
E
A
V
A
FEEKE
G
K
A
V
L
N
L
LFSPRAT
K
P
S
A
L
S
R
A
V
K
V
F
E
T
F
E
A
K
I
H
HLETRPAQRPRAGGPH
L
E
Y
F
V
R
L
E
VRR
G
D
L
A
A
L
L
S
G
V
R
Q
V
S
E
D
VRSPAGPKVPWF
P
R
K
V
S
E
L
D
K
C
H
H
L
V
T
KFDPDLDLDHPGF
S
D
Q
V
Y
R
Q
R
R
K
L
I
A
E
I
A
F
Q
YRHGDPIPR
V
E
Y
T
A
E
E
I
A
T
W
K
E
V
Y
T
T
L
K
G
L
Y
A
T
H
A
C
G
E
H
L
E
A
F
A
L
L
E
R
FSGYREDNIP
Q
L
E
D
V
S
R
F
L
K
ERTG
F
Q
LR
P
V
A
G
L
L
S
A
R
D
F
L
A
S
L
A
F
R
V
F
Q
C
T
Q
Y
I
R
HASSPMHSP
E
P
D
C
C
H
E
L
L
GHVPML
A
D
R
T
F
A
Q
F
S
Q
DIGLASLGA
S
D
E
E
I
E
K
L
S
T
L
Y
W
F
T
V
E
F
G
L
CKQNG
E
V
K
A
Y
G
A
G
L
L
S
S
Y
G
E
L
L
H
C
LSEEPE
I
R
A
FDPEAAAVQPYQDQ
T
Y
Q
S
V
Y
F
V
S
ESF
S
D
A
K
D
K
L
R
S
Y
A
S
R
IQR
P
F
S
V
KFD
P
Y
T
L
A
I
D
VLDS
P
Q
A
V
R
R
S
L
E
G
V
Q
D
E
L
D
T
L
A
H
A
L
S
AIG
17
PsiBlast_PDB
27.69
64%
-95
- C1 -
6PAH
1
PH4H_HUMAN
A:
[2-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
14
PsiBlast_PDB
27.58
64%
-96
- C1 -
3PAH
1
PH4H_HUMAN
A:
[2-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
16
PsiBlast_PDB
25.90
64%
-95
- C1 -
5PAH
1
PH4H_HUMAN
A:
[2-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
18
PsiBlast_PDB
25.64
64%
-95
- C1 -
1DMW
1
PH4H_HUMAN
A:
[1-307]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
8
PsiBlast_PDB
24.05
62%
-95
- C1 -
1LRM
1
PH4H_HUMAN
A:
[16-322]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
7
PsiBlast_PDB
23.13
62%
-94
- C1 -
1J8U
1
PH4H_HUMAN
A:
[16-322]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
15
PsiBlast_PDB
21.45
64%
-92
- C1 -
4PAH
1
PH4H_HUMAN
A:
[2-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
20
PsiBlast_PDB
17.88
63%
-93
- C1 -
1TG2
1
PH4H_HUMAN
A:
[2-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
T
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
12
PsiBlast_PDB
17.34
62%
-91
* C1 *
4ANP
1
PH4H_HUMAN
A:
[14-322]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
D
---------------------------
10
PsiBlast_PDB
11.67
62%
-93
- C1 -
1MMK
2
PH4H_HUMAN
A:
[15-323]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
D
---------------------------
11
PsiBlast_PDB
6.61
62%
-92
- C1 -
1MMT
2
PH4H_HUMAN
A:
[15-322]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------
9
PsiBlast_PDB
4.09
62%
-91
- C1 -
1KW0
2
PH4H_HUMAN
A:
[16-322]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
W
F
P
R
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
G
A
E
L
D
A
D
H
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
I
P
R
V
E
Y
M
E
E
E
K
K
T
W
G
T
V
F
K
T
L
K
S
L
Y
K
T
H
A
C
Y
E
Y
N
H
I
F
P
L
L
E
K
Y
C
G
F
H
E
D
N
I
P
Q
L
E
D
V
S
Q
F
L
Q
T
C
T
G
F
R
L
R
P
V
A
G
L
L
S
S
R
D
F
L
G
G
L
A
F
R
V
F
H
C
T
Q
Y
I
R
H
G
S
K
P
M
Y
T
P
E
P
D
I
C
H
E
L
L
G
H
V
P
L
F
S
D
R
S
F
A
Q
F
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
I
E
K
L
A
T
I
Y
W
F
T
V
E
F
G
L
C
K
Q
G
D
S
I
K
A
Y
G
A
G
L
L
S
S
F
G
E
L
Q
Y
C
L
S
E
K
P
K
L
L
P
L
E
L
E
K
T
A
I
Q
N
Y
T
V
T
E
F
Q
P
L
Y
Y
V
A
E
S
F
N
D
A
K
E
K
V
R
N
F
A
A
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Q
R
I
E
V
L
----------------------------