@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF14604_ACK1_HUMAN: (2014-10-20 )
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVKKPTYDPVSEDQDPLSSDFKRLGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATARLPQRGCPGDGPEAGRPADKIQMAMV
Atome Classification :
(13 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQPEEGT
G
W
L
L
E
L
L
S
E
V
Q
L
Q
Q
Y
F
L
R
L
RDDLN
V
T
R
L
S
H
F
E
Y
V
K
NE
D
L
E
K
IGMGRP
G
Q
R
R
L
W
E
A
V
K
R
R
K
A
L
C
K
R
K
S
W
M
S
K
V
FSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGE
G
P
L
Q
S
L
T
C
L
IG
E
K
D
L
R
L
L
E
K
LGDG
S
F
G
V
V
RRGEWDAPSG
K
T
V
S
V
A
V
K
CLK
P
D
VLSQ
P
E
A
M
D
D
F
I
R
E
V
N
A
M
HSL
D
H
R
N
L
I
R
L
Y
G
V
V
LT
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
HQGH
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
GM
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
IG
D
F
G
L
M
R
ALPQNDD
H
Y
V
M
Q
E
HRKV
P
F
A
WCAPESLKTRTFSHASD
T
W
M
F
G
V
T
L
W
E
M
F
TYGQE
P
W
IGL
N
G
S
Q
I
L
H
K
I
DKEGERLPRPEDC
P
Q
D
I
Y
N
V
M
V
Q
C
WAHKPEDR
P
T
F
V
A
L
R
D
F
L
LEAQP
T
D
M
R
A
L
Q
DFEEP
D
K
L
H
I
Q
MN
D
V
I
T
V
IEGRAEN
Y
W
WRGQN
T
R
T
L
C
VGPF
P
R
N
V
V
T
S
V
AGL
S
A
Q
D
I
S
Q
P
L
Q
NS
F
I
HTGHGDSDPRHCWGF
P
D
R
I
D
E
L
YLGNPMDPP
D
L
L
S
V
ELSTSR
P
P
Q
H
LGGVKKPTYDPVSEDQD
P
L
S
S
D
F
K
R
LGLRKPGLPR
G
L
W
LAKPSARVPGTKASRGSG
A
E
V
T
L
I
DFGEEPVVPALRPC
A
P
S
L
A
Q
L
A
M
D
A
C
S
L
L
DETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDD
F
E
I
C
SINS
T
L
VGAGVPAGPSQGQT
N
Y
A
FVPEQARPPPPLEDNLFLPPQGGGKPPSS
A
Q
T
A
E
I
F
Q
A
L
Q
Q
E
C
M
R
Q
LQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRP
H
V
Q
LSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPT
T
Q
SFASDPKYATP
Q
V
IQAPGPRAG
P
C
I
L
P
I
VRDGKKVSS
T
H
Y
Y
LLPER
P
S
Y
L
E
R
Y
Q
R
F
L
R
EAQSPEEPTPLPV
P
L
L
LPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPP
R
A
TARLPQRGCPGDGPEAGR
P
A
D
K
I
Q
MAMV
23
PsiBlast_CBE
72.05
100%
-108
- C1 -
3EQR
1
ACK1_HUMAN
B:
[1-274]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
K
P
D
V
L
S
Q
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
---
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
68.89
100%
-110
- C1 -
3EQR
1
ACK1_HUMAN
A:
[1-276]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
K
------
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
P
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
62.20
100%
-107
- C1 -
3EQP
1
ACK1_HUMAN
A:
[1-274]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
------
Q
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
59.34
100%
-105
- C1 -
3EQP
1
ACK1_HUMAN
B:
[1-276]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
------
Q
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
P
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
58.99
100%
-108
- C1 -
4ID7
1
ACK1_HUMAN
A:
[1-273]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
K
P
-----
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.49
99%
-114
- C1 -
1U54
1
ACK1_HUMAN
B:
[11-282]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
---
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
--------
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
58.02
99%
-112
- C1 -
1U4D
1
ACK1_HUMAN
B:
[11-284]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
L
---------
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
---
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
N
D
D
H
Y
V
M
Q
E
H
R
K
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
56.31
99%
-112
- C1 -
1U4D
1
ACK1_HUMAN
A:
[11-283]
--------------------------------------------------------------------------------------------------------------------
L
T
C
L
I
G
E
K
D
L
R
L
L
E
K
L
G
D
G
S
F
G
V
V
R
R
G
E
W
D
A
P
S
G
K
T
V
S
V
A
V
K
C
--------
P
E
A
M
D
D
F
I
R
E
V
N
A
M
H
S
L
D
H
R
N
L
I
R
L
Y
G
V
V
L
T
P
P
M
K
M
V
T
E
L
A
P
L
G
S
L
L
D
R
L
R
K
H
Q
G
H
F
L
L
G
T
L
S
R
Y
A
V
Q
V
A
E
G
M
G
Y
L
E
S
K
R
F
I
H
R
D
L
A
A
R
N
L
L
L
A
T
R
D
L
V
K
I
G
D
F
G
L
M
R
A
L
P
Q
--
D
H
Y
V
M
-----
V
P
F
A
W
C
A
P
E
S
L
K
T
R
T
F
S
H
A
S
D
T
W
M
F
G
V
T
L
W
E
M
F
T
Y
G
Q
E
P
W
I
G
L
N
G
S
Q
I
L
H
K
I
D
K
E
G
E
R
L
P
R
P
E
D
C
P
Q
D
I
Y
N
V
M
V
Q
C
W
A
H
K
P
E
D
R
P
T
F
V
A
L
R
D
F
L
L
E
A
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
30.58
39%
-93
- C1 -
3VJO
1
A:
[8-279]
-------------------------------------------------------------------------------------------------------------
G
E
A
P
N
Q
A
L
L
R
I
L
K
E
T
E
F
K
K
I
K
V
L
G
S
--
F
G
T
V
Y
K
G
L
W
-
I
P
E
G
E
K
V
K
I
P
V
A
I
K
---
E
A
T
S
P
K
A
N
K
E
I
L
D
E
A
Y
V
M
A
S
V
D
N
P
H
V
C
R
L
L
G
I
C
L
T
S
T
V
Q
L
I
T
Q
L
M
P
F
G
C
L
L
D
Y
V
R
E
H
K
D
N
I
G
S
Q
Y
L
L
N
W
C
V
Q
I
A
K
G
M
N
Y
L
E
D
R
R
L
V
H
R
D
L
A
A
R
N
V
L
V
K
T
P
Q
H
V
K
I
T
D
F
G
L
A
K
L
L
G
A
E
E
K
E
Y
-
H
A
E
G
G
K
V
P
I
K
W
M
A
L
E
S
I
L
H
R
I
Y
T
H
Q
S
D
V
W
S
Y
G
V
T
V
W
E
L
M
T
F
G
S
K
P
Y
D
G
I
P
A
S
E
I
S
S
I
L
E
K
-
G
E
R
L
P
Q
P
P
I
C
T
I
D
V
Y
M
I
M
V
K
C
W
M
I
D
A
D
S
R
P
K
F
---
R
E
L
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
26.82
39%
-80
- C1 -
4LI5
1
A:
[1-275]
----------------------------------------------------------------------------------------------------------
G
S
M
G
E
A
P
N
Q
A
L
L
R
I
L
K
E
T
E
F
K
K
I
K
V
L
G
S
G
A
F
G
T
V
Y
K
G
L
W
-
I
P
E
G
E
K
V
K
I
P
V
A
I
K
E
L
R
E
A
T
S
P
K
A
N
K
E
I
L
D
E
A
Y
V
M
A
S
V
D
N
P
H
V
C
R
L
L
G
I
C
L
T
S
T
V
Q
L
I
T
Q
L
M
P
F
G
C
L
L
D
Y
V
R
E
H
K
D
N
I
G
S
Q
Y
L
L
N
W
C
V
Q
I
A
K
G
M
N
Y
L
E
D
R
R
L
V
H
R
D
L
A
A
R
N
V
L
V
K
T
P
Q
H
V
K
I
T
D
F
G
L
A
K
L
L
G
A
E
E
K
E
Y
-
H
A
E
G
G
K
V
P
I
K
W
M
A
L
E
S
I
L
H
R
I
Y
T
H
Q
S
D
V
W
S
Y
G
V
T
V
W
E
L
M
T
F
G
S
K
P
Y
D
G
I
P
A
S
E
I
S
S
I
L
E
K
-
G
E
R
L
P
Q
P
P
I
C
T
I
D
V
Y
M
I
M
V
K
C
W
M
I
D
A
D
S
R
P
K
F
---
R
E
L
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
25.82
39%
-81
- C1 -
3W32
1
A:
[9-275]
------------------------------------------------------------------------------------------------------------------
Q
A
L
L
R
I
L
K
E
T
E
F
K
K
I
K
V
L
G
S
G
A
F
G
T
V
Y
K
G
L
W
-
I
P
E
G
E
K
V
K
I
P
V
A
I
K
E
L
R
E
A
T
S
P
K
A
N
K
E
I
L
D
E
A
Y
V
M
A
S
V
D
N
P
H
V
C
R
L
L
G
I
C
L
T
S
T
V
Q
L
I
T
Q
L
M
P
F
G
C
L
L
D
Y
V
R
E
H
K
D
N
I
G
S
Q
Y
L
L
N
W
C
V
Q
I
A
K
G
M
N
Y
L
E
D
R
R
L
V
H
R
D
L
A
A
R
N
V
L
V
K
T
P
Q
H
V
K
I
T
D
F
G
L
A
K
L
L
G
A
E
E
K
E
Y
-
H
A
E
G
G
K
V
P
I
K
W
M
A
L
E
S
I
L
H
R
I
Y
T
H
Q
S
D
V
W
S
Y
G
V
T
V
W
E
L
M
T
F
G
S
K
P
Y
D
G
I
P
A
S
E
I
S
S
I
L
E
K
-
G
E
R
L
P
Q
P
P
I
C
T
I
D
V
Y
M
I
M
V
K
C
W
M
I
D
A
D
S
R
P
K
F
---
R
E
L
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
22.35
39%
-82
- C1 -
2GS6
2
A:
[1-275]
----------------------------------------------------------------------------------------------------------
G
A
M
G
E
A
P
N
Q
A
L
L
R
I
L
K
E
T
E
F
K
K
I
K
V
L
G
S
G
A
F
G
T
V
Y
K
G
L
W
-
I
P
E
G
E
K
V
K
I
P
V
A
I
K
E
L
---
T
S
P
K
A
N
K
E
I
L
D
E
A
Y
V
M
A
S
V
D
N
P
H
V
C
R
L
L
G
I
C
L
T
S
T
V
Q
L
I
T
Q
L
M
P
F
G
C
L
L
D
Y
V
R
E
H
K
D
N
I
G
S
Q
Y
L
L
N
W
C
V
Q
I
A
K
G
M
N
Y
L
E
D
R
R
L
V
H
R
D
L
A
A
R
N
V
L
V
K
T
P
Q
H
V
K
I
T
D
F
G
L
A
K
L
L
G
A
E
E
K
E
Y
-
H
A
E
G
G
K
V
P
I
K
W
M
A
L
E
S
I
L
H
R
I
Y
T
H
Q
S
D
V
W
S
Y
G
V
T
V
W
E
L
M
T
F
G
S
K
P
Y
D
G
I
P
A
S
E
I
S
S
I
L
E
K
-
G
E
R
L
P
Q
P
P
I
C
T
I
D
V
Y
M
I
M
V
K
C
W
M
I
D
A
D
S
R
P
K
F
---
R
E
L
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
20.36
39%
-87
- C1 -
4LQM
1
?
A:
[6-276]
--------------------------------------------------------------------------------------------------------------
E
A
P
N
Q
A
L
L
R
I
L
K
E
T
E
F
K
K
I
K
V
L
G
S
G
A
F
G
T
V
Y
K
G
L
W
-
I
P
E
G
E
K
V
K
I
P
V
A
I
K
E
L
---
T
S
P
K
A
N
K
E
I
L
D
E
A
Y
V
M
A
S
V
D
N
P
H
V
C
R
L
L
G
I
C
L
T
S
T
V
Q
L
I
T
Q
L
M
P
F
G
C
L
L
D
Y
V
R
E
H
K
D
N
I
G
S
Q
Y
L
L
N
W
C
V
Q
I
A
K
G
M
N
Y
L
E
D
R
R
L
V
H
R
D
L
A
A
R
N
V
L
V
K
T
P
Q
H
V
K
I
T
D
F
G
R
A
K
L
L
G
A
E
E
--------
G
K
V
P
I
K
W
M
A
L
E
S
I
L
H
R
I
Y
T
H
Q
S
D
V
W
S
Y
G
V
T
V
W
E
L
M
T
F
G
S
K
P
Y
D
G
I
P
A
S
E
I
S
S
I
L
E
K
-
G
E
R
L
P
Q
P
P
I
C
T
I
D
V
Y
M
I
M
V
K
C
W
M
I
D
A
D
S
R
P
K
F
---
R
E
L
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------