@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : PF00105_ESR2_HUMAN: (2016-03-19 )
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ

Atome Classification :

(66 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280........290.......300.......310.......320.......330.......340.......350.----......360.......370.......380.....-..390.......400.......410...-....-420.......430.......440.......450.......460.......470.......480...---....490.......500.......510.......520.......530
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-ATQD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
69 HHSearch 94.53100%-158 - C5 -3OLL ESR2_HUMAN A:[3-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT---ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
58 PsiBlast_CBE 94.4199%-158 - C5 -3OLL ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT---ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
34 PsiBlast_CBE 93.71100%-156 - C5 -4J24 ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
57 PsiBlast_CBE 93.4599%-160 - C5 -3OLL B:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT----DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
36 PsiBlast_CBE 92.78100%-158 - C5 -3OMQ ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
32 PsiBlast_CBE 92.76100%-159 - C5 -4J24 ESR2_HUMAN C:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
19 PsiBlast_PDB 92.38100%-158 - C5 -3OLS ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
28 PsiBlast_CBE 92.28100%-159 - C5 -1U3R B:[3-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
20 PsiBlast_PDB 92.19100%-156 - C5 -3OMO ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
42 PsiBlast_CBE 92.06100%-160 - C5 -2YJD ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
38 PsiBlast_CBE 92.00100%-157 - C5 -3OMP ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
33 PsiBlast_CBE 91.94100%-157 - C5 -4J24 ESR2_HUMAN B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
31 PsiBlast_CBE 91.77100%-161 - C5 -4J24 D:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS---------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
11 PsiBlast_PDB 91.76100%-156 - C5 -1U3R ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM--------QD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
3 PsiBlast_PDB 91.74100%-158 - C5 -1QKM A:[6-246] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
41 PsiBlast_CBE 91.69100%-158 - C5 -2YJD B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
47 PsiBlast_CBE 91.54100%-156 - C5 -1U3S B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
37 PsiBlast_CBE 91.50100%-161 - C5 -3OMP B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
18 PsiBlast_PDB 91.46100%-152 - C5 -1U3S ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY----------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
40 PsiBlast_CBE 91.40100%-159 - C5 -3OLS B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
35 PsiBlast_CBE 91.37100%-160 - C5 -3OMQ B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
39 PsiBlast_CBE 91.33100%-161 - C5 -3OMO B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
15 PsiBlast_PDB 91.04100%-157 - C5 -1X7B ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
30 PsiBlast_CBE 90.98100%-155 - C5 -4J26 ESR2_HUMAN A:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS------------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
10 PsiBlast_PDB 90.86100%-156 - C5 -1U9E ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
12 PsiBlast_PDB 90.59100%-160 - C5 -2GIU A:[1-241] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKC-EGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM----VV---PVYDLLLEMLNAHVL------------------------------
49 PsiBlast_CBE 90.57100%-159 - C5 -1U3Q ESR2_HUMAN C:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
29 PsiBlast_CBE 90.56100%-155 - C5 -4J26 B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM-----------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
17 PsiBlast_PDB 90.56100%-157 - C5 -1U3Q ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
45 PsiBlast_CBE 90.54100%-155 - C5 -1X78 B:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
2 PsiBlast_PDB 90.50100%-159 - C5 -1YYE ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
52 PsiBlast_CBE 90.46100%-157 - C5 -2NV7 ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
65 HHSearch 90.42100%-158 - C5 -1YYE ESR2_HUMAN A:[2-238] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
44 PsiBlast_CBE 90.39100%-155 - C5 -1X7B B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
54 PsiBlast_CBE 90.3899%-154 - C5 -1ZAF ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
67 HHSearch 90.29100%-158 - C5 -1L2J ESR2_HUMAN A:[27-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR-----TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS----LVT-ATQD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
14 PsiBlast_PDB 90.29100%-157 - C5 -1X78 ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
53 PsiBlast_CBE 90.2899%-157 - C5 -1ZAF B:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
9 PsiBlast_PDB 90.15100%-152 - C5 -1NDE A:[15-254] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRPS--FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----ATQD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCK------PVYDLLLEMLNAHVL------------------------------
16 PsiBlast_PDB 90.09100%-158 - C5 -1X7J ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
48 PsiBlast_CBE 90.06100%-161 - C5 -1U3Q D:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
43 PsiBlast_CBE 89.92100%-156 - C5 -1X7J B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
51 PsiBlast_CBE 89.86100%-154 - C5 -2NV7 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
56 PsiBlast_CBE 89.8599%-162 - C5 -2YLY ESR2_HUMAN A:[2-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
22 PsiBlast_CBE 89.74100%-160 - C5 -1YY4 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
13 PsiBlast_PDB 89.69100%-156 - C5 -1X76 ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
4 PsiBlast_PDB 89.6997%-158 - C5 -1L2J ESR2_HUMAN A:[27-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR-----TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS----LVT-ATQD-ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
46 PsiBlast_CBE 89.60100%-155 - C5 -1X76 B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
21 PsiBlast_CBE 89.10100%-153 - C5 -1YYE B:[1-234] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLN----------------------------------
59 PsiBlast_CBE 89.0791%-158 - C5 -2J7Y A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-VS-----FTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
60 PsiBlast_CBE 89.0191%-157 - C5 -2J7X A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-VS---MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
24 PsiBlast_CBE 88.93100%-159 - C5 -2Z4B B:[12-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAHVL------------------------------
5 PsiBlast_PDB 88.93100%-158 - C5 -2I0G ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
7 PsiBlast_PDB 88.92100%-157 - C5 -2Z4B ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
1 PsiBlast_PDB 88.83100%-154 - C5 -1YY4 ESR2_HUMAN A:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
50 PsiBlast_CBE 88.78100%-159 - C5 -1U3Q ESR2_HUMAN B:[1-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
27 PsiBlast_CBE 88.48100%-157 - C5 -2I0G B:[12-250] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
55 PsiBlast_CBE 88.3899%-154 - C5 -2YLY B:[1-238] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
8 PsiBlast_PDB 88.21100%-159 - C5 -2QTU ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISRP------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK---------VYDLLLEMLNAH--------------------------------
25 PsiBlast_CBE 88.16