@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : 5HT1A_HUMAN: (2016-01-08 )
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100........110---.........120........130.......140..---.....150....-...160......-.170..-..------..----..180-----..--....------..190..---.--......200----.-......210.......------------------220----------------.......230.......240.......250.......260-------------...-----....270...-------------------.------------.--..280......-----------.-----290.....--------..300.......310.......320..--------------.....330...-.----------.------------.--------------------------------------------.-----340.......350.......360.......370...----....380.........390.......400.......410.......420
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNK-WTLGQVTCD-----LFIALDVLCCT-SSILHLCAIALDRYWAITDPIDY---VNKRTPRRAAAL-ISLTWLIGFLIS-IP-PML-GW------RT----PEDR------SD--PDAC------TIS--KD---H--GYTIYSTFG----A-FYIPLLLMLVLYGRIF------------------RAA----------------RFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRN-------------WRL-----GVESKAGGAL-------------------C------------A--NGAVRQGDDGA-----------A-----LEVIEVHR--------VGNSKEHLPLPSEAGPTPCAPASFERK--------------NERNAEAKRKM-A----------L------------A--------------------------------------------R-----ERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSC----HMPTL--LGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
1 PsiBlast_PDB 85.5040%-108 - C4 -4IAR C562_ECOLX A:[15-398] ------------------------------ISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGR-WTLGQVVCD-----FWLSSDITCCT-ASIWHLCVIALDRYWAITDAVEY---SAKRTPKRAAVM-IALVWVFSISIS-LP-PFF--W------RQ----A--------------SEC------VVN--TD---HI-LYTVYSTVG----A-FYFPTLLLIALYGRIY------------------VEA----------------RSRI-----------ADLEDNWETLNDNLKVIEKADNAAQ-------------VKD-----ALTKMRAAAL-------------------D------------A--QKATPPKLEDK-----------S-----PDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLK--------------TTRNAYIQKYL-A-----------------------A--------------------------------------------R-----ERKATKTLGIILGAFIVCWLPFFIISLVMPI---------WFHLA--IFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK----
9 PsiBlast_PDB 83.7928%-168 - C4 -3P0G ENLYS_BPT4 A:[46-476] ----------------------------------------IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKM-WTFGNFWCE-----FWTSIDVLCVT-ASIETLCVIAVDRYFAITSPFKY---QSLLTKNKARVI-ILMVWIVSGLTSFLP-IQM-HW------YR----ATHQEAINCYAE--ETCC------DFF--TN---Q--AYAIASSIV----S-FYVPLVIMVFVYSRVF------------------QEAK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L---------------------------------------------------------K-----EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI----RKEVY--I--LLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCLRR---
4 PsiBlast_PDB 81.0531%-118 - C4 -4NC3 C562_ECOLX A:[33-415] ---------------------------------------ALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCP-----AWLFLDVLFST-ASIWHLCAISVDRYIAIKKPIQ----ANQYNSRATAFIKITVVWLISIGIA-IPVPIK-GI------ET-----VDN------PN--NITC------VLT--KE---RFGDFMLFGSLA----A-FFTPLAIMIVTYFL---------------------------------------------TIHALQKKAADLEDNWETLNDNLKVIEKADNAAQ-------------VKD-----ALTKMRA------------------------------------------------------------------------KDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLK--------------TTRNAYIQKYLQT----------I------------S--------------------------------------------N-----EQRASKVLGIVFFLFLLMWCPFFITNITLVLCD-SC----NQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR--
12 PsiBlast_PDB 80.4128%-106 - C4 -3PDS ADRB2_HUMAN (first) A:[14-444] ----------------------------------------IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAACILMKM-WTFGNFWCE-----FWTSIDVLCVT-ASIETLCVIAVDRYFAITSPFKY---QSLLTKNKARVI-ILMVWIVSGLTSFLP-IQM-HW------YR----ATHQEAINCYAE--ETCC------DFF--TN---Q--AYAIASSIV----S-FYVPLVIMVFVYSRVF------------------QEAKRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQ-----DVDAAVRGILRNAKLKPVYDSLDAVRRAAL------------I--NMVFQMGETGV-----------AGFTNSLRMLQQKR--------WDEAAVNLAKSRWYNQTPNRAKRVITT--------------FRTGTWDAYKF-C----------L---------------------------------------------------------K-----EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI----RKEVY--I--LLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL-----
17 PsiBlast_PDB 80.3732%-108 - C4 -4EIY AA2AR_HUMAN (first) A:[45-428] -------------------------------------------------AILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAI---------TISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRY---NGLVTGTRAKGI-IAICWVLSFAIG-LT-PML-GW------NNCGQPKEGK------NH--SQGCGEGQVACLF--EDVVPM--NYMVYFNFF----ACVLVPLLLMLGVYLRIF------------------LAA----------------RRQL-----------ADLEDNWETLNDNLKVIEKADNAAQ-------------VKD-----ALTKMRAAAL-------------------D------------A--QK-------------------------------MKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLK--------------TTRNAYIQKYL-E----------R------------A--------------------------------------------RSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCS----HAPLW--LMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHV---
19 PsiBlast_PDB 80.2629%-106 - C4 -3EML ENLYS_BPT4 A:[35-472] -------------------------------------------------AILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAI---------TISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRY---NGLVTGTRAKGI-IAICWVLSFAIG-LT-PML-GW------NNCGQ---------------SQGCGEGQVACLF--EDVVPM--NYMVYFNFF----ACVLVPLLLMLGVYLRIF------------------LAARRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQ-----DVDAAVRGILRNAKLKPVYDSLDAVRRAAL------------I--NMVFQMGETGV-----------AGFTNSLRMLQQKR--------WDEAAVNLAKSRWYNQTPNRAKRVITT--------------FRTGTWDAYRS-T----------L------------Q--------------------------------------------K-----EVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCS----HAPLW--LMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
3 PsiBlast_PDB 80.2031%-115 - C4 -4IB4 5HT2B_HUMAN (first) A:[33-415] ---------------------------------------ALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCP-----AWLFLDVLFST-ASIWHLCAISVDRYIAIKKPIQ----ANQYNSRATAFIKITVVWLISIGIA-IPVPIK-GI------ET-------N------PN--NITC------VLT--KE---RFGDFMLFGSLA----A-FFTPLAIMIVTYFL---------------------------------------------TIHALQKKAADLEDNWETLNDNLKVIEKADNAAQ-------------VKD-----ALTKMRAAAL-------------------D------------A--QK--------------------------------KDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLK--------------TTRNAYIQKYLQT----------I------------S--------------------------------------------N-----EQRASKVLGIVFFLFLLMWCPFFITNITLVLCD-SC----NQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR--
10 PsiBlast_PDB 80.1428%-107 - C4 -2RH1 ADRB2_HUMAN (first) A:[45-475] ----------------------------------------IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKM-WTFGNFWCE-----FWTSIDVLCVT-ASIETLCVIAVDRYFAITSPFKY---QSLLTKNKARVI-ILMVWIVSGLTSFLP-IQM-HW------YR----ATHQEAINCYAE--ETCC------DFF--TN---Q--AYAIASSIV----S-FYVPLVIMVFVYSRVF------------------QEAKRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQ-----DVDAAVRGILRNAKLKPVYDSLDAVRRAAL------------I--NMVFQMGETGV-----------AGFTNSLRMLQQKR--------WDEAAVNLAKSRWYNQTPNRAKRVITT--------------FRTGTWDAYKF-C----------L---------------------------------------------------------K-----EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI----RKEVY--I--LLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL-----