@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : 5HT1B_HUMAN: (2016-01-08 )
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS

Atome Classification :

(22 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180...---.--------..----.190--..-----.....200..-.....210.......220.......230.......240...--------..------------------------------..250.--..-----------------------..-------------..260-------.--.-----.-----...-..-.270.------------------------------------------...-----------.-----------.-----------------.----280----..-----...--.---------..290--------..--------------.--------------......300--------......--------------------------------------------..310.......320.......330.......340..--.....350.......360.......370.......380.......390
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPF---F--------WR----QAKA--EE-----EVSECVVNTD-HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPN--------RT------------------------------GKRLTR--AQ-----------------------LI-------------TDS---------P--G-----S-----TSS-VT-SINSR------------------------------------------VPD-----------V-----------P-----------------S----ES-----GS-----PVY--V---------NQV----------KV--------------R--------------VSDALLEK---------KKLMAA--------------------------------------------RERKATKTLGIILGAFIVCWLPFFIISLVMPICKDAC--WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
1 PsiBlast_PDB 88.2676%-137 - C5 -4IAR C562_ECOLX A:[9-398] -------------------------------------YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPF---F--------WR----QA-------------SECVVNTD-HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKV------------------------------IEKADN--AA-----------------------QV-------------KDALTKMRAAALD--A-----Q-----KAT-PP-KLEDK------------------------------------------SPD-----------S-----------P-----------------EMKDFRH-----GF-----DIL--V---------GQIDDALKLANEGKV--------------K--------------EAQAAAEQLKTTRNAYIQKYLAA--------------------------------------------RERKATKTLGIILGAFIVCWLPFFIISLVMPI-------WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK---
61 HHSearch 67.9130%-114 - C5 -3UON ACM2_HUMAN (first) A:[25-457] --------------------------------------------------FIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAI---LF-------WQ----FIVGVRTV-----EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEML--------RI------------------------------DEGLRLKIYK-----------------------DTEGYYTIGIGHLLTKSP---------SLNAAKSELDKAIGRNTN-GV-ITKDE------------------------------------------AEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMG----ET-----GVAGFTNSLRMLQQKRWDEAAVNLA----------KS--------------RWYNQTPNRAKRVITTFRTGTWD---------AYPPPS--------------------------------------------REKKVTRTILAILLAFIITWAPYNVMVLINTFCAP----CIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-----
34 PsiBlast_CBE 67.3234%-142 - C5 -2Y02 ADRB1_MELGA B:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRK--ID--------RA------------------------------SKRKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
9 PsiBlast_PDB 66.7534%-153 - C5 -2Y02 ADRB1_MELGA A:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
10 PsiBlast_PDB 66.5034%-153 - C5 -2Y03 ADRB1_MELGA A:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
14 PsiBlast_PDB 66.4534%-150 - C5 -3ZPR ADRB1_MELGA A:[4-299] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLL------
24 PsiBlast_CBE 66.2434%-145 - C5 -2YCW ADRB1_MELGA B:[4-299] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRK--ID--------RA------------------------------SKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLAF----
31 PsiBlast_CBE 66.1434%-140 - C5 -3ZPQ ADRB1_MELGA B:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRK--ID--------RA------------------------------SKRKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
8 PsiBlast_PDB 66.0834%-152 - C5 -2Y01 ADRB1_MELGA A:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
33 PsiBlast_CBE 65.8934%-140 - C5 -2Y03 ADRB1_MELGA B:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRK--ID--------RA------------------------------SKRKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
7 PsiBlast_PDB 65.8834%-151 - C5 -2Y00 ADRB1_MELGA A:[4-300] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLLA-----
30 PsiBlast_CBE 65.8634%-142 - C5 -3ZPR ADRB1_MELGA B:[4-299] -----------------------------------------ELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHW--------WRDEDPQALK--CY-----QDPGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRK--ID--------RA------------------------------SKRKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRVMLM--------------------------------------------REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVA----FNWLGYANSAMNPIIYCRS-PDFRKAFKRLL------