@TOME V2.3
(Nov 2016)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : 5HT1D_HUMAN: (2016-01-08 )
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS

Atome Classification :

(26 SA) .........10........20........30........40........50........60........70........80........90........100........110.......120.......130.......140.......---150.......160.......170.--.---.-....180--..------..------....190.-......200.......210.......220.......230.----------....----..-----240---------.-------.------.---------.--...-----------.----------------250---.-----.-----.--...-------------------.--------------------260------------------------.-----------------.---------------..----------..-----.-.270-------------------.----.-.-----.-----.-------.---.--------.280------------........---------.--290.......300.......310.......320.......330.......340.......350.......360.......370.....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTI-THTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKR---RTAGHAATMIAIVWAISICISIPP--L---F-WRQAKA---QE------EM------SDCLVNTS-QISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPS----------LYGK----RF-----TT----------A-------H------L---------I--TGS-----------A----------------GSS---L-----C-----S--LNS-------------------S--------------------LH-------------------------E-----------------G---------------HS----------HS-----A-GSP--------------------L----F-F-----N-----H-------V---K--------IK--------------LADSALER---------K--RISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
1 PsiBlast_PDB 89.4955%-145 - C4 -4IAR C562_ECOLX A:[20-398] -------------------------------------KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTV-TGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAK---RTPKRAAVMIALVWVFSISISLPP--F---F-WRQA---------------------SECVVNTD-HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKVIEK----AD-----NA----------A-------Q------VKDA------L--TKM-----------R----------------AAA---L-----D-----A--QKA-------------------T--------------------PP-------------------------K-----------------L---------------ED----------KS-----P-DSPEMKDFRHGFDILVGQIDDALK----L-A-----N-----E-------G---K--------VK--------------EAQAAAEQLKTTRNAYIQ--KYLAARERKATKTLGIILGAFIVCWLPFFIISLVMPI-----WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK---
8 PsiBlast_PDB 74.5433%-152 - C4 -2Y00 ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----
69 HHSearch 74.4733%-127 - C4 -3PBL DRD3_HUMAN (first) A:[41-472] ----------------------------------------YALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPL--L---F-GFNTTG-----------DP------TVCSISNP---DFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKNIF----------EMLRIDEGLR-----LKIYKD------T-------E------GYYTIGIGHLL--TKSPSLN-------AAKSELDKA--------IGR---NTNGVIT-----K--DEA-------------------EKLFNQDVDAAVRGILRNAKLKPVYDSLDAVR----------------R-----------------AALINMVFQMGETGVAGFTN--------SL-----RMLQQ--------------------K----RWDEAAVNL-----A-------K---SRWYNQTPNRAKRVIT---------TFRTGTWD---------A--YGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQT-CHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC----
27 PsiBlast_CBE 74.3334%-150 - C4 -2VT4 ADRB1_MELGA B:[9-299] -----------------------------------QWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R----------------------------------------EHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLAF----
2 PsiBlast_PDB 74.2834%-151 - C4 -3SN6 R:[183-490] --------------------------------------VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL-TKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSL---LTKNKARVIILMVWIVSGLTSFLPIQM---H-WYR------QEAINCYAEE------TCCDFFTN-Q-AYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDK----------SEG-----R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLKEHKALKTLGIIMGTFTLCWLPFFIVNIV-HVIQDNL-IRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLC-----
63 HHSearch 74.2428%-128 - C4 -3UON ACM2_HUMAN (first) A:[24-457] --------------------------------------VFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTV-IGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVK---RTTKMAGMMIAAAWVLSFILWAPA--I---L-FWQFIVGVRTV------ED------GECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEM----------LRID----EGLRLKIYKDTEGYYTIGIG-------H------L---------L--TKS-----------PSLNAAKSELDKAIGRNTNGVITK-----D-----E--AEK-------------------LFNQDVDAAVRGILRNA----KLKPVYDSLDAVRRAALINMVFQMGETG-----------------V---------------AGFTNS------LR-----M-LQQ--------------------K----R-W-----DEAAVNL-------A---K--------SRWYNQTPNRAKRVITTFRTGTWD---------A--YPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAP--CIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-----
15 PsiBlast_PDB 74.1433%-148 - C4 -3ZPR ADRB1_MELGA A:[8-299] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLL------
11 PsiBlast_PDB 74.0133%-153 - C4 -2Y03 ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R--------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----
10 PsiBlast_PDB 73.9133%-154 - C4 -2Y02 ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----
14 PsiBlast_PDB 73.8433%-148 - C4 -3ZPQ ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----
9 PsiBlast_PDB 73.5833%-153 - C4 -2Y01 ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----
7 PsiBlast_PDB 73.4534%-141 - C4 -2YCY ADRB1_MELGA A:[10-299] ------------------------------------WEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R----------------DRASKR---------K--RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLAF----
13 PsiBlast_PDB 73.4133%-149 - C4 -4AMJ ADRB1_MELGA A:[8-300] ----------------------------------QQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-WRDEDP---QALKCY--QD------PGCCDFVT-NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL--VPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA-----