@TOME V2.3
(Nov 2016)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : 5HT1F_HUMAN: (2016-01-08 )
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80....-....90........100.......110.......120.......130..---.....140.......150......--.---160--..---.---.---..-----..170....-.-..180.......190.......200.......210------------........220...-----...---.----230-----.-------.-...-------------...--.---------------240.....------..--------------250---------...---------.------------------------------..----------..--------------260-----------...-----.--------...-------------.---270---------.----........280-...-----...------...290.......300.......310.......320.......330.......340.......350.......360....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIV-RESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARK---RTPKHAGIMITIVWIISVFISMPP--L---F-W--RH---Q---G---TS-----RDDECIIKH-D-HIVSTIYSTFGAFYIPLALILILYYKIYRAAKTL-------------YHKRQASRIAKEEV-----NGQ---V----L-------L-------E-SGE-------------KST--K---------------SVSTSYVL------EK--------------SL----------SDP---------S------------------------------TD----------FD--------------KI------------HST-----V--------RSL-------------R---S-----------E----FKHEKSWRR---QKI-----SGT------RERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
1 PsiBlast_PDB 93.9846%-137 - C4 -4IAR C562_ECOLX A:[17-398] -------------------LPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTV-TGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAK---RTPKRAAVMIALVWVFSISISLPP--F---F-W--RQ---A----------------SECVVNT-D-HILYTVYSTVGAFYFPTLLLIALYGRIYVEAR---------------------SRIADLED-----NWE---T----LNDN----L-------K-VIE-------------KAD--N---------------AAQVKDAL------TKMRAAALDAQKATPPKL----------EDK---------S------------------------------PDSPEMKDFRHGFD--------------ILVGQIDDALKLANEGK-----V--------KEA-------------Q---A-----------A----AEQLKTTRNAYIQKY-----LAA------RERKATKTLGIILGAFIVCWLPFFIISLVMPI----WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK-
2 PsiBlast_PDB 85.4229%-127 - C4 -4U15 ACM3_RAT A:[13-398] -----------------------VFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYII-MNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAK---RTTKRAGVMIGLAWVISFVLWAPAI-L---F-W--QYFVGK---R---TV-----PPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKMNIFEMLRIDEGGGSGGDEAEKLFNQDV-----DAA---V----RGILRNAKL-------K-PVY-------------DSL--D---------------AVRRAALI------NM--------------VF----------QMG---------E------------------------------TG----------VA--------------GF------------TNS-----L--------RMLQQKRWDEAAVNLAK---S-----------R----WYNQTPNRA---KRVITTFRTGTWDAYLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSC-IPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKTL-----
57 HHSearch 82.1229%-118 - C4 -3UON ACM2_HUMAN (first) A:[23-457] ----------------------VVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTV-IGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVK---RTTKMAGMMIAAAWVLSFILWAPA--I---LFW--QF---I---VGVRTV-----EDGECYIQF-FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSR-------------INIFEMLRIDEGLR-----LKIYKDTEGYYTIGI----GHLLT---KSPSLNAAKSELDKAIGRNTN--GVITKD----------EAEKLFNQ------DV--------------DA----------AVR---------GILRNAKLKPVYDSLDAVRRAALINMVFQMGET----------GVAGF-----------TN------------SLRMLQ--QK-------RWDEA-----------AVNLAKSRWYNQTPNRAKRVITTFRTGTWD---AYP-----PPS------REKKVTRTILAILLAFIITWAPYNVMVLINTFCAP-CIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM---
8 PsiBlast_PDB 81.9131%-139 - C4 -2YCY ADRB1_MELGA A:[14-297] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYRE--------------------------AKEQI-----R---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRASKR---KRV-----MLM------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF--
12 PsiBlast_PDB 81.6231%-156 - C4 -2Y03 ADRB1_MELGA A:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQIR---------------------------------------------------------------------------------SRVML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---
7 PsiBlast_PDB 81.4131%-143 - C4 -2YCZ ADRB1_MELGA A:[14-297] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYRE--------------------------AKEQI-----R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIDRASKR---KRV-----MLM------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF--
61 HHSearch 81.2632%-125 - C4 -3PBL DRD3_HUMAN (first) A:[41-472] -------------------------YALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPL--L---FGF--NT---T--------G-----DPTVCSISN-P---DFVIYSSVVSFYLPFGVTVLVYARIYVVLKQR-------------RRKNIFEMLRIDEGLRLKIYKD---T----E-------GYYTIGIGH-LLT-------------KSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDV--------------DAAVRGILRNAKLKPVYDSLDAVRR------------------------------AA----------LINMVFQMGETGVAGFTN------------SLRMLQQKRWDEAAVNLAKS-------------R---WYNQTPNR----AKRVITTFRTGTWD---AYG-----VPL------REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC--
3 PsiBlast_PDB 81.2629%-129 - C4 -4U16 ? A:[13-388] -----------------------VFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYII-MNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAK---RTTKRAGVMIGLAWVISFVLWAPAI-L---F-W--QYFVGK---R---TV-----PPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKMNIFEMLRIDEGGGSGGDEAEKLFNQDV-----DAA---V----RGILRNAKL-------K-PVY-------------DSL--D---------------AVRRAALI------NM--------------VF----------QMG---------E------------------------------TG----------VA--------------GF------------TNS-----L--------RMLQQKRWDEAAVNLAK---S-----------R----WYNQTPNRA---KRVITTFRTGTWDAYLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSC-IPKTYWNLGYWLCYINSTVNPVCYALCN---------------
9 PsiBlast_PDB 81.1632%-147 - C4 -3SN6 R:[185-490] -------------------------MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL-TKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSL---LTKNKARVIILMVWIVSGLTSFLPIQM---H-WYR-----QEAIN---CY-----AEETCCDFF-T-NQAYAIASSIVSFYVPLVIMVFVYSRVFQEA------------------KRQLQKIDKSEG-----R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C----LK----------------------------EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNL-IRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLC---
22 PsiBlast_CBE 81.0831%-137 - C4 -2YCY ADRB1_MELGA B:[14-297] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYRE--------------------------AKEQI-----R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIDRASKR---KRV-----MLM------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF--
34 PsiBlast_CBE 80.7531%-145 - C4 -2Y02 ADRB1_MELGA B:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQIRKI-----------------------------------------D-------------RAS--K---------------RKTSRVML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---
15 PsiBlast_PDB 80.7231%-151 - C4 -3ZPR ADRB1_MELGA A:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQ--------------------------------------------------------------------------------------ML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLL----
14 PsiBlast_PDB 80.4131%-151 - C4 -3ZPQ ADRB1_MELGA A:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQ-----------------------------------------------------------------------------------SRVML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---
36 PsiBlast_CBE 80.3731%-146 - C4 -2Y00 ADRB1_MELGA B:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQIRKI-----------------------------------------D-------------RAS--K---------------RKTSRVML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---
23 PsiBlast_CBE 80.3731%-143 - C4 -2YCX ADRB1_MELGA B:[14-297] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYRE--------------------------AKEQI-----R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIDRASKR---KRV-----MLM------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---
13 PsiBlast_PDB 80.3031%-152 - C4 -4AMJ ADRB1_MELGA A:[14-299] -------------------------MSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVV-RGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLP--IMMHW-W--RD---E---D---PQALKCYQDPGCCDFV-T-NRAYAIASSIISFYIPLLIMIFVALRVYREA------------------KEQ-----------------------------------------------------------------------------------SRVML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------REHKALKTLGIIMGVFTLCWLPFFLVN-IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA---