@TOME V2.3
(Nov 2016)

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3D Common Core:

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Modeller Result :

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : 5HT7R_HUMAN: (2016-01-08 )
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD

Atome Classification :

(24 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.---......200.......210..-.....-220...----.--------.-------..230------..-------..--..---...240.......250.......260......----------------------------------------.270-.......280-------..-------------------------.-------------.----------------------------.-----------------------------.-----------.290-----..------.---------------.------------------------------------------..--------------------------------------------------.----------------------------------------------.--------------------------------------------.--------------------------300------------.---------------.---.------------------------.--.------------.----------.---------.310.......320--.........330.......340.......350.......-360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR---QNGKCMAKMILSVWLLSASIT-LPPLF-GWAQNV----N--------D-------DKV--------CL-------IS--QD---FGYTIYSTAVAFYIPMSVMLFMYYQIYKAARK----------------------------------------SAAK-HKFPGFPRVE-------PD-------------------------S-------------V----------------------------I-----------------------------A-----------LN-------GI------V---------------K------------------------------------------LQ--------------------------------------------------K----------------------------------------------E--------------------------------------------V--------------------------E-E------------C---------------A---N------------------------L--S------------R----------L---------LKHERKNISIFK----REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS-CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
74 HHSearch 91.0535%-136 - C5 -3PBL DRD3_HUMAN (first) A:[41-472] -----------------------------------------------------------------------------------YALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVS-CPLLF-GFNTTG-------------D-------PTV--------CS-------IS--N----PDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQ----------------------------------------RRRK-NIFEMLRIDEGLRLKIYKD-------------------------T-------------E----------------------------GYYTIGIGHLLTKSPSLNAAKSELDKAIGRN-----------TN-------GV------I---------------T------------------------------------------KD--------------------------------------------------E----------------------------------------------AEKLFNQDVDAAVRGILRNAKLKPVYDSLDAV-------------RRAALINMVFQMGETGVAGFTNSLRMLQQK------------RWDEAAVNLAKSRWYNQ---TPN----------------------R--AKRVIT-------T----------F---------RTGTWDAYGVPL----REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQT---C-HVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC------------------------------------------------------------------------------
1 PsiBlast_PDB 89.3336%-145 - C5 -4IAR C562_ECOLX A:[20-396] --------------------------------------------------------------------------------KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMP-ISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAK---RTPKRAAVMIALVWVFSISIS-LPPFF--WRQA-------------------------SE------CV-------VN--TDH--ILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQK-ATPPKLEDKS-------PD-------------------------SPEMKDFRHGFDILV----------------------------G-----------------------------Q-----------ID-------DA------L---------------K------------------------------------------LA--------------------------------------------------N----------------------------------------------EGK------------------------------------------V--------------------------K-E------------A---------------Q---A------------------------A--A------------E----------Q---------LKTTR-NAYIQKYLAARERKATKTLGIILGAFIVCWLPFFIISLVMP-I-------WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK-----------------------------------------------------------------------------
67 HHSearch 88.9231%-144 - C5 -2RH1 ADRB2_HUMAN (first) A:[38-477] ------------------------------------------------------------------------------VWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH-ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSL---LTKNKARVIILMVWIVSGLTS-FLPIQMHWYRAT----HQ-------EAINCYAEETC--------CD-------FF--TN---QAYAIASSIVSFYVPLVIMVFVYSRVFQEAKR----------------------------------------QLNI-FEMLRIDEGL-------RLKIYKDTEGYYTIGIGHLLTKSPSLNA-------------A----------------------------KS----------------------------ELDKAIG-----RN-------TNGVITKDE---------------AEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMG--------------------------------------------------ETGVAGFTNSLRMLQQK------------------------------R--------------------------------------------W--------------------------D-EAAVNL-------A---------------K---SR-----------------------W--YNQTPNRAKRVITT----------F---------RTGTWDAYKFCL----KEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD----N-LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAFQELLCL------------------------------------------------------------------------------
66 HHSearch 83.8231%-129 - C5 -3UON ACM2_HUMAN (first) A:[22-457] -------------------------------------------------------------------------------EVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLY-TVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVK---RTTKMAGMMIAAAWVLSFILW-APAIL-FWQFIVGVRTV--------E-------DGE--------CY-------IQ--FFSN-AAVTFGTAIAAFYLPVIIMTVLYWHISRASKS----------------------------------------RINI-FEMLRIDEGL-------RL-------------------------KIYKDTE-------GYYTIGIGHLLTKSPSLNAAKSELDKAIGR-----------------------------N-----------TN-------GV------I---------------T------------------------------------------KD--------------------------------------------------EAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGET--------------------------------------------G--------------------------V-AGFTNSLRMLQQKRWDEAAVNLAKS----R---W------------------------YNQT------------PNRAKRVITT-F---------RTGTWDAYPPPS----REKKVTRTILAILLAFIITWAPYNVMVLINTFCAP-----CIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-------------------------------------------------------------------------------
70 HHSearch 79.9730%-128 - C5 -3RZE ENLYS_BPT4 (first) A:[10-443] ----------------------------------------------------------------------------------PLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILY-LLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKY---RTKTRASATILGAWFLSFLWV-IPIL--GWNH------R--------R-------EDK--------CE-------TD--FYDV-TWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQ----------------------------------------HCNI-FEMLRIDEGL-------RLKIYKDTEGYYTIGIGHLLTKSPS--L-------------N----------------------------A-----------------------------AKSELDKAIGRNTN-------GV------I---------------T------------------------------------------KD--------------------------------------------------E----------------------------------------------AEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGE--------------------------T-G------------V---------------AGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ--T------------P----------NRAKRVITTFRTGTWDAYLHMN----RERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKN-----CCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHI------------------------------------------------------------------------------
72 HHSearch 79.9428%-133 - C5 -3EML ENLYS_BPT4 A:[20-472] -------------------------------------------------------------------------------GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITI-S--TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGL---VTGTRAKGIIAICWVLSFAIG-LTPML-GWNNCG----Q----------------SQG--------CGEGQVACLFE--DVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARR----------------------------------------QLNI-FEMLRIDEGL-------RL-------------------------K-------------IYKDTEGYYTIGIGHLLTKSPSLN-----A-----------------------------A-----------KSELDKAIGRN------TNGVITKDEAEKLFNQD------------------------------------------VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQ----------------------------------------------KRW------------------------------------------D--------------------------E-A------------AVNL------------A---KSRWY--------------------N--QT-----------PNRAKRVITTFR---------TGTWDAYRSTLQ----KEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPD--CS-HAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ-------------------------------------------------------------------------
16 PsiBlast_PDB 79.3231%-149 - C5 -3SN6 R:[164-489] ---------------------------------------------------ITTFRTGTWDA---------------EVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF-GAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSL---LTKNKARVIILMVWIVSGLTSFLPIQM-HWYR---------------Q-------EAINCYAEETCCD-------FF--TN---QAYAIASSIVSFYVPLVIMVFVYSRVFQEAKR----------------------------------------QLQKIDKSEGR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CL----KEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----QDN-LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAFQELLC-------------------------------------------------------------------------------
15 PsiBlast_PDB 79.1833%-136 - C5 -4BVN ADRB1_MELGA A:[17-300] --------------------------------------------------------------------------------------LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPF-GATLVVRGTWLWGSFLCELWTSLDVLCVTASVETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLPIMM-HWWRDE----DPQALKCYQD-------PGC--------CD-------FV--TN---RAYAIASSIISFYIPLLIMIFVALRVYREAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-Q------------I---------------R------------------------------------------------------------------KRKTSRV-MLM----REHKALKTLGIIMGVFTLCWLPFFLVNIVNVF----NRD-LVPKWLFVAFNWLGYANSAMNPIILC-RSPDFRKAFKRLLA-------------------------------------------------------------------------------
14 PsiBlast_PDB 78.9633%-145 - C5 -3ZPR ADRB1_MELGA A:[17-299] --------------------------------------------------------------------------------------LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPF-GATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLPIMM-HWWRDE----DPQALKCYQD-------PGC--------CD-------FV--TN---RAYAIASSIISFYIPLLIMIFVALRVYREAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-Q-------------------------------------------------------------------------------------------------------MLM----REHKALKTLGIIMGVFTLCWLPFFLVNIVNVF----NRD-LVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLL--------------------------------------------------------------------------------
38 PsiBlast_CBE 78.6731%-170 - C5 -4MQT ACM2_HUMAN A:[39-334] -------------------------------------------------------------------------------EVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIG-YWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVK---RTTKMAGMMIAAAWVLSFILW-APAIL-FWQFIV----GVRTV----E-------DGE--------CY-------IQFFSN---AAVTFGTAIAAFYLPVIIMTVLYWHISRASK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PS-------REKKVTRTILAILLAFIITWAPYNVM-----VLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMC------------------------------------------------------------------------------
27 PsiBlast_CBE 78.4034%-147 - C5 -2VT4 ADRB1_MELGA B:[17-299] --------------------------------------------------------------------------------------LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPF-GATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLPIMM-HWWRDE----DPQALKCYQD-------PGC--------CD-------FV--TN---RAYAIASSIISFYIPLLIMIFVALRVYREAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-Q------------I---------------R----------------------------------------------------------------------------------EHKALKTLGIIMGVFTLCWLPFFLVNIVNVF----NRD-LVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF------------------------------------------------------------------------------
7 PsiBlast_PDB 78.1733%-145 - C5 -2Y00 ADRB1_MELGA A:[17-300] --------------------------------------------------------------------------------------LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPF-GATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL---MTRARAKVIICTVWAISALVSFLPIMM-HWWRDE----DPQALKCYQD-------PGC--------CD-------FV--TN---RAYAIASSIISFYIPLLIMIFVALRVYREAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-Q---------------------------------------------------------------------------------------------------SRV-MLM----REHKALKTLGIIMGVFTLCWLPFFLVNIVNVF----NRD-LVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA-------------------------------------------------------------------------------