@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ADA2A_HUMAN: (2016-01-08 )
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

Atome Classification :

(20 SA) .........10........20..-..-....30.....------...40.....----...50........60........70........80.....-...90.....-.-..100.......110.......120.......130...---....140.---......150.......160.....-..170.......180..------..---.-..190-..------..--....200.......210....-...220.......230...-------------------..---..240-.-....-..250.......260.......270....-----------...280.......290.......300....-----...310-.......320......-.330.--....--------..340.--------......--------350.......360...----------------------.----------------------...370--..-------------------.....380.......390.......--.--400----.--....-...410.......420.......430.....-..-440.......450
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGSLQPDAGNASWNGTEAPGGGA-RA-TPYSLQVTLTL------VCLAGLLMLL----TVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLV-IPFSLANEVM-G-YWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSI---TQAIEYNL---KRTPRRIKAIIITVWVISAVISFP-PLISIEKKGGGGGPQPA------EP---R-CEIN--DQ------KW--YVISSCIGSFFAPCLIMILVY-VRIYQIAKRRTRVPPSRRG-------------------PD---AVAAP-P-GGTE-RRPNGLGPERSAGPGGAEAEPLPTQLNGA-----------PGEPAPAGPRDTDALDLEESSSSDHAERPP-----GPRRPE-RGPRGKGKARASQVKP-GDSLP--RRGP--------GATGIG--------TPAAGP--------GEERVGAAKASRWRGR----------------------Q----------------------NREKRF--TF-------------------VLAVVIGVFVVCWFPF-FFTYTLTA--V--GC-----S--VPRT-LFKFFFWFGYCNSSLNPVIYTIFNHDFRRAF-KK-ILCRGDRKRIV
4 PsiBlast_PDB 92.0131%-162 - C4 -3P0G ENLYS_BPT4 A:[47-477] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKEHKALK-----------TLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCLRR-----
6 PsiBlast_PDB 90.6231% -94 - C4 -3NY8 ENLYS_BPT4 A:[47-477] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
3 PsiBlast_PDB 90.1231% -93 - C4 -2RH1 ADRB2_HUMAN (first) A:[46-476] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
5 PsiBlast_PDB 90.0531% -98 - C4 -3D4S ENLYS_BPT4 A:[47-477] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
7 PsiBlast_PDB 89.9031% -93 - C4 -3NY9 ADRB2_HUMAN (first) A:[47-477] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
2 PsiBlast_PDB 89.4532% -95 - C4 -3PBL DRD3_HUMAN (first) A:[41-472] --------------------------------YALSYC------A-----LILA----IVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLV-MPWVVYLEVT-GGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAV---VMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCP-LLFGFNTTG--------------DP---TVCSIS--NP------D---FVIYSSVVSFYLPFGVTVLVY-ARIYVVLKQRRR----KNI-------------------FE---MLRID-E-GLRL-KIYKDTEGYYTIGIGHLLTKS-PS-LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVA--------GFTNSLRMLQQKRWDEAAVNLAK-SRWYNQ----------------------TPNRAKRVITTFRTGTWDAYGVPLREKKA--TQ-------------------MVAIVLGAFIVCWLPF-FLTHVLNTHCQ--TC-----H--VSPE-LYSATTWLGYVNSALNPVIYTTFNIEFRKAF-LK-ILSC-------
8 PsiBlast_PDB 89.4331% -95 - C4 -3NYA ADRB2_HUMAN (first) A:[47-477] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
9 PsiBlast_PDB 89.2231% -95 - C4 -3PDS ADRB2_HUMAN (first) A:[15-445] ----------------------------------------------VMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAACILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-P---IQMHWYRATHQEAINCYAEET---C-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYKFCLKEHKALKTLGIIMGTFTLCWLPF-FIVNIVHV--I--QD-----N--LIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAF-QE-LLCL-------
21 PsiBlast_CBE 87.6532% -99 - C4 -3PBL DRD3_HUMAN (first) B:[41-472] --------------------------------YALSYC------A-----LILA----IVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLV-MPWVVYLEVT-GGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAV---VMP---------SSCRRVALMITAVWVLAFAVSCP-LLFGFNTTG--------------DP---TVCSIS--NP------D---FVIYSSVVSFYLPFGVTVLVY-ARIYVVLKQRRR----KNI-------------------FE---MLRID-E-GLRL-KIYKDTEGYYTIGIGHLLTKS-PS-LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVA--------GFTNSLRMLQQKRWDEAAVNLAK-SRWYNQ----------------------TPNRAKRVITTFRTGTWDAYGVPLREKKA--TQ-------------------MVAIVLGAFIVCWLPF-FLTHVLNTHCQ--TC-----H--VSPE-LYSATTWLGYVNSALNPVIYTTFNIEFRKAF-LK-ILSC-------
11 PsiBlast_PDB 84.6527% -95 - C4 -3RZE ENLYS_BPT4 (first) A:[11-441] -------------------------------------L------VVVLSTICLV----TVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVV-MPMNILYLLM-S-KWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSV---QQPLRYLK---YRTKTRASATILGAWFLSFLWVIP-IL------GWNH-----RR----ED---K-CETDFYDV------TW--FKVMTAIINFYLPTLLMLWFY-AKIYKAVRQHCNIFEMLRI-------------------DE---GLRLKIY-KDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQTPNRAKRVITTFRTGTWDAYLHM----------------------NRERKA--AK-------------------QLGFIMAAFILCWIPY-FIFFMVIA--FCKNC-----C---NEH-LHMFTIWLGYINSTLNPLIYPLCNENFKKTF-KR-ILHI-------
15 PsiBlast_PDB 84.6425% -90 - C4 -3UON ACM2_HUMAN (first) A:[20-456] -------------------------------TFEVVFI------VLVAGSLSLV----TIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFS-MNLYTLYTVI-G-YWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCV---TKPLTYPV---KRTTKMAGMMIAAAWVLSFILWAP-AILFWQFIVGVRTVEDG------EC---Y-IQFF--SN------AA--VTFGTAIAAFYLPVIIMTVLY-WHISRASKSRINIFEMLRI-------------------DE---GLRLK-IYKDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TPNRAKRVITTFRTGTWDAYPPPSREKKV--TR-------------------TILAILLAFIITWAP--YNVMVLIN--T--FC-----APCIPNT-VWTIGYWLCYINSTINPACYALCNATFKKTF-KH-LLM--------
10 PsiBlast_PDB 83.6527% -81 - C4 -4DAJ ACM3_RAT (first) A:[18-440] ----------------------------------------------LTGFLALV----TIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS-MNLFTTYIIM-N-RWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSI---TRPLTYRA---KRTTKRAGVMIGLAWVISFVLWAP-AILFWQYFVGKRTVPPG------EC---F-IQFL--SE------PT--ITFGTAIAAFYMPVTIMTILY-WRIYKETEKMNIFEMLRID-------------------EG---LRLKI-Y-KDTEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------TP---------------------NRAKRVITTFRTGTWDAYLIKEAQ-----TLSAILLAFIITWTPYNIMVLVNTF--C--DS-----C--IPKT-YWNLGYWLCYINSTVNPVCYALCNKTFRTTF-KT------------
1 PsiBlast_PDB 82.7832% -83 - C4 -4IAR C562_ECOLX A:[9-395] -----------------------------YIYQDSISLPWKVLLVMLLALITLA----TTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILV-MPISTMYTVT-G-RWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAI---TDAVEYSA---KRTPKRAAVMIALVWVFSISISLP-PFFWRQA-----------------S---E-CVVNT-DH------IL--YTVYSTVGAFYFPTLLLIALY-GRIYVEARSR----------------------------------IADL-E-DNWE-TLNDNLKVIEKAD-NAAQVKDALTKMRAA-----------ALDAQKATPP-----KLEDKS---------------PDSPEMKDFRHGFDILVGQIDD-ALKLA--NEGK--------VK-------------EAQAA--------AEQLKTTRNAYIQKYL----------------------A----------------------ARERKA--TK-------------------TLGIILGAFIVCWLPF-FIISLVMP--I---------W--FHLA-IFDFFTWLGYLNSLINPIIYTMSNEDFKQAF-HK-LIRFK------
14 PsiBlast_PDB 82.2927% -81 - C4 -4U14 ENLYS_BPT4 A:[18-443] ----------------------------------------------LTGFLALV----TIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS-MNLFTTYIIM-N-RWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSI---TRPLTYRA---KRTTKRAGVMIGLAWVISFVLWAP-AILFWQYFVGKRTVPPG------EC---F-IQFL--SE------PT--ITFGTAIAAFYMPVTIMTILY-WRIYKETEKMNCFEMLRID-------------------EG---LRLKI-Y-KDCEGYYTIGIGHLLTKSPS----------LNAA-----------KSELDKAIGRNTNGV-----ITKDEAEKLF-----N---QD-VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRW--------DEAAVNLAK-SRWYNQ----------------------CP---------------------NRAKRVITTFRTGTWDAYLIKEKKAAQ--TLSAILLAFIITWTPYNIMVLVNTF--C--DS-----C--IPKT-YWNLGYWLCYINSTVNPVCYALCNKTFRTTF-KTLLL---------
64 Fugue 78.3625% -71 - C4 -2RH1 ADRB2_HUMAN (first) A:[36-477] ------------------------------DEVWVVGM------GIVMSLIVLA----IVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV-VPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI---TSPFKYQS---LLTKNKARVIILMVWIVSGLTSFL-PIQMHWYRATHQEAINC------YAEETC-CDFF--TN------QA--YAIASSIVSFYVPLVIMVFVY-SRVFQEAKRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIG---HLLTK-S-PSLN-AAKSELDKAIGRNTNGVITKDEAEKLFNQ-----------DVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETG-VAGFTNSLRMLQQKRW-DEAAV--NLAK--------SRWYNQ--------TPNRAK--------RVITTFRTGTWDAYKF----------------------C----------------------LKEHKA--LK-------------------TLGIIMGTFTLCWLPF-FIVNIVHVI-Q--DN-----L--IRKE-VYILLNWIGYVNSGFNPLIYCR-SPDFRIAF-QE-LLCL-------