@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ADA2C_HUMAN: (2016-01-08 )
MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110..-.-....120.......130.......140.......150.......160--........170.......------180...-..--..190.--------.....---.200------...----.--....--210.......220.......230---....-----...---------------.---------.240-..-------...-...----------------------250--------..-------------.--------------....---260-.........270....-...280.......290...-----------....300.------......310.......320........330.......340.......350.......360.----......370..-------.-----....380.......390.......400.......--------410...-....420.......430.......440.......450.......460-
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELM-A-YWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNL---KRTPRRVKATIVAVWLIS------AVISFP-PL--VSLYRQ--------PDGAA---YPQ-------CGL----N--DETW--YILSSCIGSFFAPCLIMGLVY-----ARIY-----RVA---------------K---------LRT--RT-------LSE-KRA----------------------PVG--------PD-------------G--------------ASPT---T---ENGLGAAAGAGENGHC-APPPADVEPDESSAAAERR-----------RRRGALRR------GGRRRAGAEGGAGGADG-QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRA----RSSVCRRKVAQ-------A-----REKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICR--------EACQVP-GPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ-
21 PsiBlast_CBE 89.2833%-107 - C3 -3PBL DRD3_HUMAN (first) B:[41-470] ---------------------------------------------YALSYCA--------LILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVT-GGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMP---------SSCRRVALMITAVWVLA------FAVSCP-LL--FGFNTT--------GDPTV-------------CSI----S--NPDF--VIYSSVV-SFYLPFGVTVLVY-----ARIY-----VVL---------------K---------QRR--RKNIFEMLRIDEGLRL----------------------KIY--------KDTEGYYTIGIGHLLT--------------KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRVITTFRTGTWDAYGVP-------L-----REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHC---------QTCHVS-PELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC---------
3 PsiBlast_PDB 88.9728%-157 - C3 -3P0G ENLYS_BPT4 A:[41-480] --------------------------------------------------VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L----KEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCLRR-------
2 PsiBlast_PDB 88.8233%-105 - C3 -3PBL DRD3_HUMAN (first) A:[41-470] ---------------------------------------------YALSYCA--------LILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVT-GGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLA------FAVSCP-LL--FGFNTT--------GDPTV-------------CSI----S--NPDF--VIYSSVV-SFYLPFGVTVLVY-----ARIY-----VVL---------------K---------QRR--RKNIFEMLRIDEGLRL----------------------KIY--------KDTEGYYTIGIGHLLT--------------KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRVITTFRTGTWDAYGVP-------L-----REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHC---------QTCHVS-PELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC---------
4 PsiBlast_PDB 86.1428% -91 - C3 -2RH1 ADRB2_HUMAN (first) A:[40-477] --------------------------------------------------VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
10 PsiBlast_PDB 85.0928% -90 - C3 -3PDS ADRB2_HUMAN (first) A:[9-446] --------------------------------------------------VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAACILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPS---LNAAKSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
7 PsiBlast_PDB 84.8827% -90 - C3 -3NY9 ADRB2_HUMAN (first) A:[40-478] -------------------------------------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
5 PsiBlast_PDB 84.3927% -89 - C3 -3D4S ENLYS_BPT4 A:[40-478] -------------------------------------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
6 PsiBlast_PDB 84.3727% -87 - C3 -3NY8 ENLYS_BPT4 A:[40-478] -------------------------------------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
13 PsiBlast_PDB 83.7226% -91 - C3 -4DAJ ACM3_RAT (first) A:[9-440] -----------------------------------------------IWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIM-N-RWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRA---KRTTKRAGVMIGLAWVIS------FVLWAP-AI----LFWQYFVGKRTVPPGEC---FIQ-------F-L----S--EPT---ITFGTAIAAFYMPVTIMTILY-----WRIY-----KETEKMNIFEMLRIDEGLR---------LKI--YK-------DTE-GYY----------------------TIG--------IG-------------HLLT-----------KSPS---LNAAKSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYLI--KE---AQTLSAILLAFIITWTPYNIMVLVNTFC---------DSC-IP-KTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKT-------------
8 PsiBlast_PDB 83.4927% -88 - C3 -3NYA ADRB2_HUMAN (first) A:[40-478] -------------------------------------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PIQ-MHWYRA--------THQEAINCYAEETC----CDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRV----ITTF-RTGTWD-------AYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----------QDNLIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------
17 PsiBlast_PDB 81.9026% -90 - C3 -4U14 ENLYS_BPT4 A:[8-443] ----------------------------------------------TIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIM-N-RWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRA---KRTTKRAGVMIGLAWVIS------FVLWAP-AI----LFWQYFVGKRTVPPGEC---FIQ--------FL----S--EPT---ITFGTAIAAFYMPVTIMTILY-----WRIY-----KETEKMNCFEMLRIDEGLR---------LKI--YK-------DCE-GYY----------------------TIG--------IG-------------HLLT-----------KSPS---LNAAKSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRCALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQCPNRAKRV----ITTF-RTGTWD-------AYLI--KEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---------DSC-IP-KTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKTLLL----------
14 PsiBlast_PDB 80.9426% -86 - C3 -3UON ACM2_HUMAN (first) A:[20-457] -----------------------------------------------TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVI-G-YWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPV---KRTTKMAGMMIAAAWVLSFILWAPAILFWQ-FI--VGVRTV--------EDGEC---YIQ-------FFS----N--AAV----TFGTAIAAFYLPVIIMTVLY-----WHIS-----RAS---------------K---------SRI--NI-------FEM-LRI----------------------DEGLRLKIYKDTE-------------GYYTIGIGHLLT---KSPSLNAA---KSELDKAIGRNTNGVI-TKDEAEKLFNQDVDAAVRG-----------ILRNAKLKPVYDSLDAVRRAALINMVFQMGE-TGVAGFTNSLRMLQQKRWDEAAVNL--AKSRWYNQTPNRAKRVITTFRTGTWDAYPPP-------S-----REKKVTRTILAILLAFIITWAPYNVMVLINTFC----------APCIP-NTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM----------
35 Fugue 80.4326% -85 - C3 -2RH1 ADRB2_HUMAN (first) A:[36-477] ----------------------------------------------DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM-K-MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS---LLTKNKARVIILMVWIVS------GLTSFL-PI--QMHWYR--------ATHQE---AINCYAEETCCDF----F--TNQA--YAIASSIVSFYVPLVIMVFVY-----SRVF-----QEA---------------K---------RQL--NI-------FEM-LRIDEGLRLKIYKDTEGYYTIGIGHLLT--------KS-------------P--------------SLNA---A---KSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGI-----------LRNAKLKP------VYDSLDAVRRAALINMV-FQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRA----KRVITTFRTGTWDAYKFCL-----KEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD--------N--LIR-KEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL---------