@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AGRB2_HUMAN: (2016-01-08 )
MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQEANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEGTPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320......----.330.....--..340---.------......--..350.......360.......370.......380.----......390--..--.----..----..400.......410-.-......420.......430-----.....--...-440.......450.--..--.--.--....460.....-.-.-470.......480.....------..490--.--.-.....500....--...510.......520-.-......530.......540...-....550.......560.......------------570...---....580.......590.......------600.......610.......620.......630....---...640.......650-----......----------..-----------660.......670.......680.---......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.----------------..----------------....840....--...850.--......860.......870....----...880.......890.......-900.......910....-----...920.......930.......940.......950--.......960.......970.......980.....--------..990.......1000......1010.....-.1020---........1030-----.-----.......1040......1050......1060.......1070..-------..--..1080......1090......1100......1110......1120......1130......1140......1150......1160......1170.....-------.1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLTCGQG----LQVRTRSCV--SSP-----Y------GTLCSG--PLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRG----SRSRMRTCV--PP--Q----HG----GKACEGPELQTKLCS-M-AACPVEGQWLEWGPWGPC------STSCA--NGT-QQRSRKCSVAG--P--AW--A--T--CTGALTDTRECS-N-L-ECPATDSKWGPWNAWSLC------SKTCD--T--G-WQRRFRMCQATG--TQGYPCEGTGEEVKPC-S-EKRCPAFHEMCRDEYVMLMTWK-KAAAGEIIYNKCPPNASGSASRRC------------LLSAQG---VAYWGLPSFARCISHEYRYLYLSL------REHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDL---LFSVDILRNVTDTFK------RATYVP----------SA-----------DDVQRFFQVVSFMVDAENKEKWDD---AQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRP----------------PL----------------AVTSRVMTVTV--RPPTQPP--AEPLITVELSYIINGTTDPHCAS----WDYSRADASSGDWDTENCQTLET-QAAHTRCQCQHLSTFAV-----LAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLA--IYAAFWRFIKSERSIILLNFCLSILASNILILVGQ--------SRVLSKGVCTMTAAFLHFFFLSSFCWVLTEA-WQS-----YLAVIGRMRT-------R-----LVRKRFLCLGWGLPALVVAVSVGFTRTKG-YGTSSYCWLSLEGG-------LL--YAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDR-------RSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQEANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEGTPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV
21 PsiBlast_CBE 91.6550% -97 - C2 -4DLO B:[7-370] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RC-S-EQRCPAPYEICPEDYLMSMVWK-RTPAGDLAFNQCPLNATGTTSRRC------------SLSLHG---VAFWEQPSFARCISNEYRHLQHSI------KEHLA-------GDGMSQVTKTLLDLTQRKNFYAGDL---LMSVEILRNVTDTFK------RASYIP----------AS-----------DGVQNFFQIVSNLLDEENKEKWED---AQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDWARNSEDRVVIPKSIFT--------------------------------------------SVFVLGAVLYKNLDLILPTLRN----------------YT----------------VINSKIIVVTI--RPEP-------SFLEIELAHLANGTLNPYCVL----WDD------LGTWSTQGCKTVLT-DASHTKCLCDRLSTFAI-----LAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 Fugue 67.9222% -73 - C2 -4DLQ A:[18-381] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSPELFCEPREVRRVQWP-ATQQGMLVERPCPKGTRGIASFQC------------L-PALG---LWNPRGPDLSNCTSPWVNQVAQKI------K----------SGENAANIASELARH-TRGSIYAGDV---SSSVKLMEQLLDILD------AQLQALRNKMHKRERTCK-----------DYIKAVVETVDNLLRPEALESWKDMN-ATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFPQEYA---------SESSIQLSANTIKQNSRN---------------------------------------GVVKVVFILYNNLGLFLSTENA----------------TVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFL--MDPVIFTVAHLEAKNHFNANCSF----WNYSERS-MLGYWSTQGCRLVES-NKTHTTCACSHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 66.3719% -62 - C2 -4DLQ A:[23-381] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FCEPREVRRVQWP-ATQQGMLVERPCPKGTRGIASFQC------------L-PALG---LWNPRGPDLSNCTSPWVNQV----------------AQKIKSGENAANIASELARH-TRGSIYAGDV---SSSVKLMEQLLDILDAQLQALR-----------------NKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATM-LLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFP-------QEYASESSIQL-------------------SANTIKQNSRNGVVK----------------------VVFILYNNLGLFLSTENATVKLAGEAGTGGPGGASL----------------VVNSQVIAASI--NKESSRVFLMDPVIFTVAHLEAKNHFNANCSF----WNYSE-RSMLGYWSTQGCRLVES-NKTHTTCACSHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 HHSearch 57.6334% 53 - C- -1W0R - PROP_HUMAN A:[107-383] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEMGGWSGWGPWEPCSVTCSKG----TRTRRRACN--HPAPK---C------GGHCPG--QAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS--AP--EPSQKPP----GKPCPGLAYEQRRCTGL-PPCPVAGGWGPWGPVSPC------PVTCG--LGQ-TMEQRTCNHPVPQH--GG--P--F--CAGDATRTHICN-T-AVPCPV-DGEWDSWGEWSPCIRRNMKSISCQEIP--G-QQSRGRTCRGRK--FDGHRCAGQQQDIRHC-YSIQHCPL-----------KGSWSEWSTWGLC-MPPCGPNPTRARQRLC------------TPLLPK---YPPTVSMVEGQGEKNVTFWGRPLP------RCEELQGQKLVVEEKRPCLHVPACKDPEEEEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 56.3829% 48 - C- -1W0S - PROP_HUMAN A:[115-425] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WGPWEPCSVTCSKG----TRTRRRACNHPAPK-----C------GGHCPG--QAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS--AP--E----PSQKPPGKPCPGLAYEQRRCTGL-PPCPVAGGWGPWGPVSPC------PVTCG--LGQ-TMEQRTCNHPV--P--QH--G--GPFCAGDATRTHICN-TAV-PCP-VDGEWDSWGEWSPCIRRNMKSISCQ--EIPG-QQSRGRTCRGRK--FDGHRCAGQQQDIRHCYS-IQHCP-----------LKGSWS-EWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRP-LPRCEELQGQKLVVEE------KRPCLHVPACKDPEEEEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 56.3829% 48 - C- -1W0R - PROP_HUMAN A:[115-425] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WGPWEPCSVTCSKG----TRTRRRACNHPAPK-----C------GGHCPG--QAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS--AP--E----PSQKPPGKPCPGLAYEQRRCTGL-PPCPVAGGWGPWGPVSPC------PVTCG--LGQ-TMEQRTCNHPV--P--QH--G--GPFCAGDATRTHICN-TAV-PCP-VDGEWDSWGEWSPCIRRNMKSISCQ--EIPG-QQSRGRTCRGRK--FDGHRCAGQQQDIRHCYS-IQHCP-----------LKGSWS-EWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRP-LPRCEELQGQKLVVEE------KRPCLHVPACKDPEEEEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 Fugue 53.0619% -84 - C2 -4K5Y CRFR1_HUMAN (first) A:[13-423] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HYHVAAIINYLGHCISLVALLVAFVLFLRARSIR----------------CLRNIIHANLIA------AFILRNATWFV--VQLTMSP--EVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNSNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRSALINMVFQ--------MGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYDR-----LRAWMFICIGWGVP---FPIIVAWAIGKL-YYDNEKCWAGKRPG-------VYTDYIYQGPMALVLLINFIFLFNIVRILMTKLRAS---------------------------------TTSETIQARKAVKATLVLLPLLGITYMLAFV--NEV-------SRVVFIYFNAFLESFQGFFVSVFACFLNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 49.1035% 84 - C3 -3R6B A:[9-123] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQDGGWSHWSPWSSCSVTCGDG----VITRIRLCN--SP--SPQ--MN----GKPCEGEARETKACK-K-DACPINGGWGPWSPWDIC------SVTCG--GGV-QKRSRLCNNPTPQF--GG--K--D--CVGDVTENQICN-K-Q-DCP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 49.0241% 86 - C3 -3R6B A:[11-123] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGGWSHWSPWSSCSVTCGDG----VITRIRLCN--SPSPQ----MN----GKPCEGEARETKACK-K-DACPINGGWGPWSPWDIC------SVTCG--GGV-QKRSRLCNNPT--P--QF--GGKD--CVGDVTENQICN-K-Q-DCP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56 Fugue 48.8942% 94 - C3 -1LSL A:[1-113] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDGGWSHWSPWSSCSVTCGDG----VITRIRLCNSPSP--Q----MN----GKPCEGEARETKACK-K-DACPINGGWGPWSPWDIC------SVTCG--GGV-QKRSRLCNNPT--P--QFGGK--D--CVGDVTENQICN-K-Q-DC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 HHSearch 48.3338% 38 - C- -1W0R - PROP_HUMAN A:[162-383] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS--APEPSQKPP------GKPCPG--LAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLG----QTMEQRTCN--HPVPQ----HG----GPFCAGDATRTHICN-TAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQ-QSRGRTCRGRK--F--DG--H--R--CAGQQQDIRHCYSI-Q-HCPL-KGSWSEWSTWGLC------MPPCG--P--NPTRARQRLCTPLL--PKYPPTVSMVEGQGEK-N-VTFWGRPLPRCEELQGQKLVVE-EKRPCLHVPACKDPEEEEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 HHSearch 47.4511%-112 * C2 *2Z73 OPSD_TODPA A:[39-332] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFIGICGIIGCGGNGIVIY--LFTKT-KSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMIS-IDR-----YNVIGRPMAA-------SKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNIL--CMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKE-------------------LRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAGE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 46.7241% 94 - C3 -1LSL A:[2-113] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGGWSHWSPWSSCSVTCGDG----VITRIRLCN--SPSPQ----MN----GKPCEGEARETKACK-K-DACPINGGWGPWSPWDIC------SVTCG--GGV-QKRSRLCNNPT--P--QF--GGKD--CVGDVTENQICN-K-Q-DC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 HHSearch 46.6436% 130 - C3 -1LSL A:[3-110] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGWSHWSPWSSC------SVTCG--DGV-ITRIRLCNSPSPQM--NG--K--P--CEGEARETKACK-K-D-ACPI-NGGWGPWSPWDIC------SVTCG--G--G-VQKRSRLCNNPTPQFGGKDCVGDVTENQIC-N-KQDC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 HHSearch 46.0043% 104 - C3 -1LSL A:[2-109] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGGWSHWSPWSSCSVTCGDG----VITRIRLCN--SPSPQ----MN----GKPCEGEARETKACK-K-DACPINGGWGPWSPWDIC------SVTCG--GGV-QKRSRLCNNPT--PQFGG--K--D--CVGDVTENQICN-K-Q-DC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 HHSearch 45.7036% 92 - C3 -3R6B A:[9-123] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQDGGWSHWSPWSSCSVTCGDG----VITRIRLCN--SPSPQM--N------GKPCEG--EARETKACKK-DACPINGGWGPWSPWDICSVTCGGG----VQKRSRLCN--NP--TPQ--FG----GKDCVGDVTENQICN-K-QDCP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 43.7134% 37 - C3 -3T5O CO6_HUMAN A:[8-99] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WTQWTSCSKTCNSG----TQSRHRQIV--VDK-----YYQENFCEQICSK----QETREC-NWQRCPINCLLGDFGPWSDCDPCIEKQ----SKVR-SVLR--PS--Q----FG----GQPCTAPLVAFQPCI-P-SKLCKIEEADCKNKFRCD------SGRCI--ARK-LECNGENDCGD--N--SD--E--R--DCGRTKAVCTRK-Y-N-PIPSVQLMGNGFHFLAGE------PRGEV--L--D-NSFTGGICKTVK--SSRTSNPYRVPANLEN-V-GFEVQTAEDDLKTDFYKDLTSL-GHVPIFYSSKRSENINHNSAFKQA------------IQASHK---KDSSFIRIHKVMKVLNFTTKAKDL------HLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSG---SLGGVYDLLYQFSSE------ELKNSG----------LT-----------EEEAKHCVRIETKKRVLFAKKTKV---EHRCTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDG----------------QW----------------GCWSSWSTCDA--TYKRSRT--RECNNPAPQRGGKRCEGEKRQEE----DCTPCINDDEEDSGCPQPVPPEN-GFIRNEKQLYLVGEDVE-----ISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECI--KPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAG--------PSRYTCQGNSWTPPISNSLTCEKDTGHCQLG-QKQ-----SGSECICMSP-------E-----EDCSHHSEDLCVFDTDSNDYFTSPACKFL-AEKCLNNQQLHFLH-------IG--SCQDGRQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 42.2134% 40 - C3 -4A5W CO6_HUMAN B:[8-99] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WTQWTSCSKTCNSG----TQSRHRQIV--VDK-----YYQENFCEQICSK----QETREC-NWQRCPINCLLGDFGPWSDCDPCIEKQ----SKVR-SVLR--PS--Q----FG----GQPCTAPLVAFQPCI-P-SKLCKIEEADCKNKFRCD------SGRCI--ARK-LECNGENDCGD--N--SD--E--R--DCGRTKAVCTRK-Y-N-PIPSVQLMGNGFHFLAGE------PRGEV--L--D-NSFTGGICKTVK--SSRTSNPYRVPANLEN-V-GFEVQTAEDDLKTDFYKDLTSL-QGGSSFSVPIFYSSKRSENINHNS------------AFKQAI---QASHKKDSSFIRIHKVMKVLNFTT------KAKDLHLSDVFLKALNHLPLEYNSALYSRIFDDFGTH---YFTSGSLGGVYDLLY------QFSSEE----------LK-----------NSGLTEEEAKHCVRIETHRCTTNK---LSEKHEGSFIQGAEKSISLIRGGEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNN----------------PA----------------PQRGGKRCEGE--KRQEEDC--TFSIMENNGQPCINDDEEMKEVD----LPEIEADSGCPQPVPPENGFIRN-EKQLYLVGEDVEISCLT-----GFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQ--EVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYT--------CQGNSWTPPISNSLTCEKDTLTKLKGHCQLG-QKQ-----SGSECICMSP-------E-----EDCSHHSEDLCVFDTDSNDYFTSPACKFL-AEKCLNNQQLHFLH-------IG--SCQDGRQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------