@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : AGRL4_HUMAN: (2016-01-09 )
MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
Atome Classification :
(20 SA)
....-.....10-........20....--....30--...-.-.....40.-.-......50-----..------------.......60......-..---70.......----.80....-....90......---..100......-----.110--.........-----------120.......130........140.......150.......160.......170.--------......----180.......190.......200.......210.......220.......230.......240.......250.......260...--..--..270.......280------....-...290.......300....-...310.......320.......330--.........340...-....350.......360..-----.....370.-......380.......390...----....400.......410.......420.......430.......440----........450........460.......470.....-..-------480--.-------..------......-------490.......500.......510....-...520....----.-------..---530.--..-....540.......550-.-.-.--.---..------.560..-..--.---------.-----------.----------570.......580.......590.......600--------.---......610...-...-..620.......-630......-.640------.-----------------....-...-.--650.......660.......670.-......680.......690
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKRL-
P
L
L
V
V
F
S
-
T
L
LNCSYTQNCTKT--PCLPN---AK
C
-
E
-IRNG
I
E
A
C
-Y-CNMGFSG------N
G
------------
V
T
I
CEDDNEC
G
N
L
T
Q
-
S
C---GENANCTNT----EG
S
Y
Y
C
M
-CVPGFRSSSNQD---
R
F
ITNDG
T
V
C
I
-----EN----VNANCHLD
N
-----------
V
C
I
AAN
I
N
K
T
L
-
T
K
I
R
S
I
K
E
P
V
A
L
L
Q
E
V
Y
R
NSVTDL
S
P
T
D
I
I
T
Y
I
E
I
L
AES
S
S
LL--------GYKNNT----ISAKDTLS
N
S
T
L
T
E
F
V
K
T
V
N
N
F
V
QRD
T
F
V
V
W
D
KLSV
N
H
R
R
T
H
L
T
K
L
M
H
T
V
E
Q
A
T
L
R
I
S
Q
S
F
Q
KTTEFDTNS
T
D
I
A
L
K
V
F
F
FDSYNM--
K
H
--IHPHMNMDG
D
Y
I
N
I
F------PKRK-AAYDSNG
N
V
A
V
A
F
V
Y
YKSI
G
-
P
LLSSSD
N
F
L
L
KPQNYDN
S
E
E
E
E
R
----
V
I
S
S
V
I
S
V
SMSSNPP-
T
L
Y
E
L
E
K
I
T
F
T
LSH
R
K
V
T
D
-----
R
Y
R
S
L
C
A
FW-NYSPDTMNGSWSSE
G
C
E
L
T
YSN----ETH
T
S
C
R
CNH
L
T
H
F
A
I
L
MSSGPSIGI
K
D
Y
N
I
L
T
R
I
T
Q
L
G
I
I
I
S
L
I
C
-----
L
A
I
C
I
F
T
F
W
F
-
F
S
E
I
Q
S
T
R
T
T
I
H
K
N
L
C
C
S
L
F
L
A
E
L
V
F
-
L
V-------G----I-------NT------N
T
N
K
L
F
-------
C
S
I
I
A
G
L
L
H
Y
F
F
L
A
A
F
A
W
M
C
I
E
G
I
H
L
Y
-
L
I
V
V
G
V
I
YNK----G-------
F
L
---HK
N
F
--
Y
I
-
F
G
YL
S
P
A
V
V
V
G
F
S
A
AL
G
-
Y
-
R
-
Y
--Y---G
T
------
T
K
V
C
W
L
-ST--E---------N-----------
N
----------
F
I
W
SFI
G
P
A
C
L
I
I
L
V
N
L
L
A
F
G
V
I
I
Y
K
V
F
R
H
TAG--------L---KP
E
V
S
C
F
E
-
N
I
R
-
S
C
A
-
R
G
A
L
A
L
L
F
L
L
G
T
-
T
W
I
F
G
V
L
H
V
-
V
H
--------
A
-----------------
S
V
V
T
-
A
Y
L
-
F
--
T
V
S
N
A
F
Q
G
M
F
I
F
L
F
L
C
V
L
S
R
K
I
Q
E
-
E
Y
Y
R
L
F
KNV
P
C
C
F
GCLR
71
Fugue
70.60
19%
-66
* C6 *
4DLQ
16
A:
[18-381]
--------------------------------------------------------------------------------------------------------------
V
----
S
P
E
L
F
C
E
-
P
R
E
V
R
R
V
Q
W
P
A
T
---
Q
Q
G
M
L
V
E
R
P
C
P
-----
K
G
T
R
G
I
A
S
F
Q
C
L
P
A
L
GLWNPRGPDLS
N
C
T
S
P
W
V
N
Q
V
A
-
Q
K
I
K
S
G
E
N
A
A
N
I
A
S
E
L
A
R
H
T
R
G
S
I
Y
A
G
D
V
S
S
S
V
K
L
M
E
Q
L
L
D
I
L
--------
D
A
Q
L
Q
A
L
RN
K
M
H
K
R
E
R
T
C
K
D
Y
I
K
A
V
V
E
T
V
D
N
L
L
R
P
E
A
L
E
S
W
K
D
M
N
A
T
E
Q
V
H
T
A
T
M
L
L
D
V
L
E
E
G
A
F
L
L
A
D
N
V
R
E
P
A
R
F
L
A
A
K
Q
N
V
V
L
E
V
T
V
L
S
T
E
G
Q
V
Q
E
L
--
V
F
P
Q
E
Y
A
S
E
S
S
I
Q
L
S
------
A
N
T
I
-
K
Q
N
S
R
N
G
V
V
K
V
V
F
I
L
Y
N
N
L
G
-
L
F
L
S
T
E
N
A
T
V
K
L
A
G
E
A
G
T
G
G
P
G
G
A
SLV-
V
N
S
Q
V
I
A
A
S
I
N
K
E
S
S
-
R
V
F
L
M
D
P
V
I
F
T
V
A
H
L
E
A
K
N
-----
H
F
N
A
N
C
S
F
W
-
N
Y
S
E
R
S
M
L
G
Y
W
S
T
Q
G
C
R
L
V
E
S
N
----
K
T
H
T
T
C
A
C
S
H
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
69.61
21%
-64
- C6 -
4DLQ
15
A:
[76-381]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
T
S
P
W
V
N
Q
V
A
-
Q
K
I
K
S
G
E
N
A
A
N
I
A
S
E
L
A
R
H
T
R
G
S
I
Y
A
G
D
V
S
S
S
V
K
L
M
E
Q
L
L
D
I
L
D
A
Q
L
Q
A
L
R----
N
K
----
M
H
K
R
E
R
T
C
K
D
Y
I
K
A
V
V
E
T
V
D
N
L
L
R
P
E
A
L
E
S
W
K
D
M
N
A
T
E
Q
V
H
T
A
T
M
L
L
D
V
L
E
E
G
A
F
L
L
A
D
N
V
R
E
P
A
R
F
L
A
A
K
Q
N
V
V
L
E
V
T
V
L
S
T
E
G
Q
--
V
Q
E
L
V
F
P
Q
E
Y
A
S
E
S
S
I
Q
L
S
------
A
N
T
I
-
K
Q
N
S
R
N
G
V
V
K
V
V
F
I
L
Y
N
N
L
G
--
L
F
L
S
T
E
N
A
T
V
K
L
A
G
E
A
G
T
G
G
P
G
G
ASLV
V
N
S
Q
V
I
A
A
S
I
N
K
E
S
S
-
R
V
F
L
M
D
P
V
I
F
T
V
A
H
L
E
A
K
N
-----
H
F
N
A
N
C
S
F
W
-
N
Y
S
E
R
S
M
L
G
Y
W
S
T
Q
G
C
R
L
V
E
S
N
----
K
T
H
T
T
C
A
C
S
H
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
Fugue
57.91
20%
-79
- C1 -
1YO8
26
TSP2_HUMAN
A:
[4-624]
---------------------
D
G
C
L
S
N
--
P
C
F
P
G
---
A
Q
C
-
S
S
F
P
D
G
S
W
S
C
G
F
-
C
P
V
G
F
L
G
------
N
G
-------------
T
H
C
E
D
L
D
E
C
A
L
V
P
D
-
I
C
FST
S
K
V
P
R
C
V
N
T
----
Q
P
G
F
H
C
L
P
C
P
P
R
Y
R
G
N
Q
P
V
G
V
G
L
E
A
A
K
T
E
K
Q
V
C
E
P
E
N
PC
K
D
----
K
T
H
N
C
H
K
H
A
-----------
E
C
I
Y
L
G
H
F
S
D
P
M
Y
K
C
E
C
--------------------
Q
T
G
Y
A
G
D
G
L
I
C
G
E
D
S
D
L
D
--------
G
W
P
N
L
N
----
L
V
C
A
T
N
A
T
Y
H
C
I
K
D
N
C
P
H
L
P
N
S
G
Q
E
D
----
F
D
K
D
G
---------------------
I
G
D
A
C
D
D
D
D
D
N
D
G
V
T
D
E
K
-------
D
N
C
Q
L
--
L
F
--
N
P
R
Q
A
D
Y
D
K
D
E
V
G
D
R
CDNCPY
V
H
N
P
-
A
Q
I
D
T
D
N
N
G
E
G
D
A
C
S
V
D
I
D
G
D
D
V
F
N
E
R
D
N
C
P
Y
V
Y
N
T
D
Q
R
D
T
D
G
D
G
----
V
G
D
H
C
D
N
C
P
L
V
H
N
P
D
Q
T
D
V
D
N
D
L
V
G
D
Q
C
D
N
N
E
D
I
D
DDGHQ
N
N
Q
D
N
C
P
Y
I
S
N
A
N
Q
A
D
H
D
R
D
G
Q
G
D
A
C
D
P
D
D
D
N
DGVP
D
D
R
D
N
C
R
L
V
F
N
P
D
Q
E
D
L
D
G
D
G
R
G
D
I
C
K
D
D
F
D
N
D
N
I
P
----
D
I
D
D
V
C
PENNA
I
S
E
T
D
F
R
N
F
Q
M
V
P
L
D
P
K
G
T
T
Q
I
D
P
N
W
V
I
R
H
Q
G
K
E
L
V
Q
-----------------------
T
A
------
N
S
D
P
----------
G
I
A
V
G
F
D
E
F
G
---------------
S
-
V
D
F
S
G
T
F
Y
V
N
----
T
-------
D
R
---
D
D
D
Y
A
G
F
V
-
F
G
Y
Q
S
-------
S
S
R
F
Y
-
V
-
V
M
W
--
K
---
Q
V
------
T
Q
T
Y
W
E
-
D
Q
--
P
---------
T
-----------
R
-----------
A
Y
G
Y
S
G
-
V
S
L
K
V
V
N
S
T
T
G
T
G
E
H
L
R
N
A
L
W
H
T
G
N
--------
T
---
P
G
Q
V
R
T
L
W
H
D
P
R
-
N
I
G
W
K
D
Y
T
A
Y
R
W
H
L
T
H
-
R
P
K
T
G
Y
I
R
V
L
V
H
--------
E
-----------------
G
K
Q
V
M
A
D
S
G
P
--
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
F
V
F
-----
S
Q
E
M
V
Y
F
S
D
-----
L
K
Y
E
C
R
D
48
HHSearch
55.04
16%
-161
* C5 *
2Z73
5
OPSD_TODPA
A:
[35-333]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
-----
N
G
I
V
I
Y
L
F
T
K
-
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
-------
L
----
M
T
I
S
C
F
L
K
K
W
------
I
F
G
F
A
A
-------
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
-
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
-------
R
R
---
A
F
I
M
--
I
I
-
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
-
G
A
Y
-
T
L
-
E
---
G
V
------
L
C
N
C
S
F
-
D
Y
--
I
---------
S
RD
S
T
T
R
S
N
I
L
C
M
----------
F
I
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
M
S
V
S
N
H
E
K
E
M
A
A
M
A
K
RLNAKE
L
---
R
K
A
Q
A
G
A
N
-
A
E
M
-
R
L
A
-
K
I
S
I
V
I
V
S
Q
F
L
L
-
S
W
S
P
Y
A
V
V
A
-
L
L
A
Q
FGPLEW
V
-----------------
T
P
Y
A
-
A
Q
L
-
P
--
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
-
A
I
S
Q
T
F
P
W
V
L
T
C
C
Q
F
D
D
78
Fugue
53.83
12%
-71
* C3 *
3L4G
1
SYFA_HUMAN
C:
[1-508]
M
A
D
G
-
Q
V
A
E
L
L
L
-
R
R
L
E
A
S
--
D
G
G
L
D
S
--
A
E
L
A
A
---
E
L
G
-
M
-
E
H
Q
A
V
V
G
A
-
V
-
K
S
L
Q
A
L
G
------
E
V
------------
I
E
A
E
L
R
S
T
K
H
W
E
L
T
--------
A
E
G
E
E
I
A
R
----
E
G
S
H
E
A
R
-
V
F
R
S
I
P
P
E
G
L
A
Q
---
S
E
L
M
R
L
----------------------------------------
P
S
G
K
V
G
F
-
S
K
A
M
S
-
N
K
W
I
R
V
D
K
S
A
A
D
G
P
R
V
F
R
V
V
D
S
M
E
D
E
V
Q
R
R
L
Q
L
V
R
G
G
--------
Q
A
E
K
L
G
----
E
K
E
R
S
E
L
R
K
R
K
L
L
A
E
V
T
L
K
T
Y
W
V
S
K
G
S
A
---
F
S
T
S
I
S
K
Q
E
T
E
L
S
P
E
M
I
S
S
G
------
S
W
R
D
R
P
F
K
P
Y
N
F
L
A
H
G
--------
V
L
P
D
S
--
G
H
--
L
H
P
L
L
K
V
R
S
Q
F
R
Q
I
F
------
L
E
M
G
F
T
E
M
P
T
D
N
F
I
E
S
S
F
W
N
F
------------
D
A
L
F
Q
P
Q
Q
H
-----
P
A
R
----
D
Q
H
D
T
F
F
L
R
D
P
A
E
A
L
-
Q
L
-----------
P
M
D
Y
V
Q
-----
R
V
K
R
T
H
S
Q
G
-
G
Y
G
S
Q
G
Y
K
Y
N
W
K
L
D
E
A
R
K
N
L
L
R
----
T
H
T
T
S
A
S
A
R
A
L
Y
R
L
A
Q
K
K
P
F
T
P
----------------------------------
V
K
Y
F
S
-
I
D
R
V
F
R
N
E
T
L
D
A
T
H
L
------
A
E
F
H
Q
-
I
E
-------
G
----
V
-------
V
A
------
D
H
G
L
T
L
-------
G
H
L
M
G
V
L
R
E
F
F
T
--------------------
K
L
G
I
T
Q
----
L
-------
R
F
---
K
P
A
Y
--
N
P
-
Y
T
E
P
S
M
E
V
F
S
Y
H
Q
G
L
K
K
-
W
-
V
-
E
--
V
---
G
N
------
S
G
V
-----------------------------------------
F
R
P
E
M
L
L
P
M
G
L
P
E
N
V
S
V
I
A
W
G
L
S
L
E
R
P
T
M
I
K
Y
G
--------
I
---
N
--------
N
I
R
-
E
L
V
-
G
H
K
V
N
L
Q
M
V
Y
D
S
-
P
-----------------------------------------------------------------
L
C
R
L
D
A
E
P
-
R
P
P
P
T
Q
E
A
A
--------
57
HHSearch
50.30
8%
-155
- C5 -
2KS9
1
NK1R_HUMAN
A:
[36-324]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
-----
N
V
V
V
M
W
I
I
L
A
-
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
-------
V
N
F
T
Y
A
V
H
N----
E
W
------
Y
Y
G
L
F
Y
-------
C
K
F
H
N
F
F
P
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
F
D
R
Y
-
M
A
I
I
H
P
L
Q
P
R
----
L
S
A
-----
T
A
---
T
K
V
V
--
I
C
-
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
-
T
T
E
-
T
--
M
---
P
S
------
R
V
V
C
M
I
-
E
W
--
P
EHP------
N
KIY
E
K
V
Y
H
I
C
-
V
----------
T
V
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
I
T
----
L
W
A
S
E
I
P
--------
G
DSS
D
R
Y
H
E
Q
V
S
-
A
K
R
-
K
V
V
-
K
M
M
I
V
V
V
C
T
F
A
I
-
C
W
L
P
F
H
I
F
F
-
L
L
--------
P
Y
I
NPDLYLKKF------
I
Q
Q
V
-
Y
L
A
-
I
--
M
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
-
G
F
K
H
A
F
R
C
C
P
F
I
S
A
G
D
Y
5
PsiBlast_PDB
48.63
24%
-148
- C5 -
4L6R
1
GLR_HUMAN
A:
[151-394]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
L
H
C
T
R
N
A
I
H
A
N
L
F
A
S
F
V
L
K
A
S
S
V
-
L
V
I
D
G
L
L
R
T--------------------------
L
SDGAVA
G
C
R
V
A
A
V
F
M
Q
Y
G
I
V
A
N
Y
C
W
L
L
V
E
G
L
Y
L
H
N
L
L
G
L
A
T
L
P
E
R
----
S
-------
F
F
-----
S
L
--
Y
L
G
I
G
W
G
A
P
M
L
F
V
V
P
W
A
V
V
K
-
C
-
L
-
F
--
E
---
N
V
------
Q
--
C
W
T
-
S
N
--
D
---------
N
M----------
G
----------
F
W
W
I
L
R
F
P
V
F
L
A
I
L
I
N
F
F
I
F
V
R
I
V
Q
L
L
---
V
A
K
--------
L
---
R
A
R
Q
M
H
H
T
-
D
Y
K
F
R
L
A
-
K
S
T
L
T
L
I
P
L
L
G
V
H
E
V
V
F
A
F
V
T
D
-
E
H
--------
A
Q
G
---------------
T
L
R
S
-
A
K
L
-
F
F
D
L
F
L
S
S
F
Q
G
L
L
V
A
V
L
Y
C
F
L
N
K
E
V
Q
S
-
E
L
R
R
R
W
H
R
W
R
L
G
K
V
L
W
E
59
HHSearch
45.50
11%
-147
- C5 -
2LNL
-
CXCR1_HUMAN
A:
[43-322]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
A
Y
A
L
V
F
L
L
S
L
L
G
-----
N
S
L
V
M
L
V
I
L
Y
-
S
R
V
G
R
S
V
T
D
V
Y
L
L
N
L
A
L
A
D
L
L
F
A
L
T
L
-
P
I
-------
W
----
A
A
S
K
V
N
--
G
W
------
I
F
G
T
F
L
-------
C
K
V
V
S
L
L
K
E
V
N
F
Y
S
G
I
L
L
L
A
C
I
S
V
D
R
Y
-
L
A
I
V
H
A
T
R
T
L
----
T
-------
Q
K
R
H
L
V
K
F
V
--
C
L
-
G
C
W
G
L
S
M
N
L
S
L
P
F
F
L
F
R
---
Q
-
A
--
Y
HPN
N
S
------
S
P
V
C
Y
E
-
V
L
GN
D
---------
T
AKWRM------
V
LRILP-----
H
T
F
G
F
I
V
P
L
F
V
M
L
F
C
Y
G
F
T
----
L
R
T
L
F
K
A
H
--------------------
M
G
-
Q
K
H
-
R
A
M
-
R
V
I
F
A
V
V
L
I
F
L
L
-
C
W
L
P
Y
N
L
V
L
-
L
A
--------
D
T
L
M
RTQVIQE
S
C
E
R
R
N
N
I
G
R
A
-
L
D
A
-
T
--
E
I
L
G
F
L
H
S
C
L
N
P
I
I
Y
A
F
I
G
Q
N
F
R
H
-
G
F
L
K
I
L
A
M
H
G
-------
53
HHSearch
44.01
10%
-144
- C5 -
1U19
14
OPSD_BOVIN
A:
[44-326]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
-----
N
F
L
T
L
Y
V
T
V
Q
-
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
-------
T
T
---
L
Y
T
S
L
H
G-
Y
F
------
V
F
G
P
T
G
-------
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
-
V
V
V
C
K
P
M
S
N
F
R
F
G
-
E
-------
N
H
---
A
I
M
G
--
V
A
-
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
---
S
-
R
--
Y
I
P
E
G
M
------
Q
C
S
C
G
I
-
D
Y
--
Y
TPHEETN
N
E
S
-----------
F
V
I
Y
M
------
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
E
A
A
A
Q
--------
Q
---
Q
E
S
A
T
T
Q
K
-
A
E
K
-
E
V
T
-
R
M
V
I
I
M
V
I
A
F
L
I
-
C
W
L
P
Y
A
G
V
A
-
F
Y
I
F
T
H
QGSD
F
-----------------
G
P
I
F
-
M
T
I
-
P
--
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
-
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
D
E
18
PsiBlast_PDB
43.55
28%
-147
- C5 -
4K5Y
3
CRFR1_HUMAN (first)
A:
[14-116]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
H
V
A
A
I
I
N
Y
L
G
H
C
I
S
L
V
A
-----
L
L
V
A
F
V
L
F
L
R
-
A
R
S
I
R
C
L
R
N
I
I
H
A
N
L
I
A
A
F
I
L
R
N
A
T
W
-
F
V
-------
V
----
Q
-------
L
T
M
S
P
E
V
H
Q
S
N
V
G
W
-------
C
R
L
V
T
A
A
Y
N
Y
F
H
V
T
N
F
F
W
M
F
G
E
G
C
Y
L
H
-
T
A
I
V
L
T
N
I
F
E
----
M
-------
L
R
---
I
D
E
G
--
L
R
-
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
-
L
-
L
-
T
--
K
---
S
P
------
S
L
S
V
A
K
-
S
E
--
L
---------
D
-----------
K
----------
A
I
G
R
N
S
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
--------
A
---
K
L
K
P
V
Y
D
S
-
L
D
A
-
V
R
R
-
S
A
L
I
N
M
V
F
Q
M
G
E
-
T
G
V
A
G
F
T
N
S
-
L
R
--------
M
-----------------
L
Q
Q
K
-
R
W
D
-
E
--
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
A
T
-
F
R
T
G
T
W
D
A
Y
D
R
L
R
A
W
M
F
7
PsiBlast_PDB
41.18
35%
-70
- C4 -
2RHP
2
A:
[3-80]
-----------------------
C
L
S
N
--
P
C
F
P
G
---
A
Q
C
S
S
-
F
P
D
G
S
W
S
C
G
F
-
C
P
V
G
F
L
G
------
N
G
-------------
T
H
C
E
D
L
D
E
C
A
L
V
P
D
-
I
C
FST
S
K
V
P
R
C
V
N
T
----
Q
P
G
F
H
C
L
P
C
P
P
R
Y
R
G
N
Q
P
V
G
---
V
G
L
E
A
A
K
T
E
K
Q
-----
V
C
----
E
P
E
N
P
C
K
D
K
-----------
T
H
N
C
H
K
H
A
E
C
I
-
Y
L
G
H
F
S
D
P
M
Y
K
C
E
C
Q
T
G
Y
A
G
D
G
L
I
C
G
E
D
S
D
L
D
G
W
P
S
L
N
L
V
C
A
T
--------
N
A
T
Y
H
C
----
I
K
D
N
C
P
H
L
P
N
S
G
Q
E
D
F
D
K
D
G
I
G
D
A
C
D
D
D
D
D
N
D
G
V
T
D
E
K
D
N
C
Q
L
L
F
N
P
R
Q
A
D
Y
D
K
D
E
V
G
D
R
C
D
N
C
P
Y
V
H
N
P
A
Q
I
D
T
D
N
N
G
E
G
D
A
C
S
V
--
D
I
--
D
G
D
D
V
F
N
E
R
D
N
C
P
Y
V
------
Y
N
T
D
-
Q
R
D
T
D
G
D
G
V
G
D
H
C
D
N
C
P
L
V
H
-
N
P
D
Q
T
D
V
D
N
D
L
V
G
D
Q
C
D
N
N
E
D
I
D
D
----
D
G
H
Q
N
N
Q
D
N
C
P
Y
I
S
N
-
A
N
Q
A
D
H
D
R
D
G
Q
G
D
A
C
D
P
D
D
-----
D
N
D
G
V
P
D
D
R
-
D
N
C
R
L
V
F
N
P
D
Q
E
D
L
D
G
D
G
R
G
D
I
----
C
K
D
D
F
D
N
D
N
I
P
D
I
D
D
V
C
P
E
N
N
A
I
S
E
T
D
F
R
N
F
Q
M
V
P
L
D
P
K
G
T
T
Q
I
D
P
-----
N
W
V
I
R
H
Q
G
K
E
-
L
V
Q
T
A
N
S
D
P
G
I
A
V
G
F
D
E
F
G
S
V
D
F
S
G
T
-
F
Y
-------
V
----
N
-------
T
D
------
R
D
D
D
Y
A
-------
G
F
V
F
G
Y
Q
S
S
S
R
F
Y
V
V
M
W
K
Q
V
T
Q
T
Y
W
E
D
-
Q
P
T
R
A
Y
G
Y
S
G
----
V
-------
S
L
---
K
V
V
N
--
S
T
-
T
G
T
G
E
H
L
R
N
A
L
W
H
T
G
N
T
-
P
-
G
-
Q
--
V
---
R
T
------
L
W
H
D
P
R
-
N
I
--
G
---------
W
-----------
K
----------
D
Y
T
A
Y
R
W
H
L
T
H
R
P
K
T
G
Y
I
R
V
L
V
H
E
G
K
Q
V
M
A
D
S
G
--------
P
---
I
Y
D
Q
T
Y
A
G
-
G
R
L
-
G
L
F
-
V
F
S
Q
E
M
V
Y
F
S
D
L
-
K
Y
E
C
R
D
I
-------------------------------------------------------------------------------------
56
HHSearch
40.58
15%
-132
- C5 -
3PBL
1
DRD3_HUMAN (first)
A:
[43-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
Y
C
A
L
I
L
A
I
V
F
G
-----
N
G
L
V
C
M
A
V
L
K
-
E
R
A
L
Q
T
T
T
N
Y
L
V
V
S
L
A
V
A
D
L
L
V
A
T
L
V
-
M
P
-------
W
V
V
Y
L
E
V
T
GG---
V
W
------
N
F
S
R
I
C
-------
C
D
V
F
V
T
L
D
V
M
M
C
T
A
S
I
W
N
L
C
A
I
S
I
D
R
Y
-
T
A
V
V
M
P
V
H
Y
Q
----
H
G
T
G
Q
SS
C
R
R
---
V
A
L
M
--
I
T
-
A
V
W
V
L
A
F
A
V
S
C
P
L
L
F
G
--
F
-
N
-
T
--
T
---
G
D
------
P
T
V
C
S
I
-
S
N
--
P
---------
D
F
V
I
Y
-------
S
----------
S
V
V
S
F
Y
L
P
F
G
V
T
V
L
V
Y
A
R
I
Y
V
V
L
K
Q
R
R
R
K
N
I
F
E
--------
M
---
L
R
I
D
E
G
L
R
-
L
K
I
-
Y
K
D
-
T
E
G
Y
Y
T
I
G
I
G
H
L
-
L
T
K
S
P
S
L
N
A
-
A
K
--------
S
-----------------
E
L
D
K
-
A
I
G
-
R
--
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
-
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
63
HHSearch
40.54
24%
-60
- C4 -
1YO8
3
A:
[24-140]
S
W
S
C
G
F
C
P
V
G
F
L
G
N
G
T
H
C
E
D
L
D
E
C
A
L
V
PD
I
C
F
S
T
SKV
P
R
C
-
V
-
N
T
Q
P
G
F
H
C
-
L
P
C
P
P
R
Y
R
G
------
N
Q
P
V
G
V
G
L
E
A
A
K
T
E
K
Q
V
C
E
P
E
N
P
C
K
D
K
T
H
-
N
C
---
H
K
H
A
E
C
I
Y
L
GHFS
D
P
M
Y
K
C
E
-
C
Q
T
G
Y
A
G
D
G
L
I
C
---
G
E
D
S
D
L
D
G
W
P
N
-----
L
N
----
L
V
C
A
T
N
A
T
Y
-----------
H
C
I
K
D
N
C
P
H
L
P
-
N
S
G
Q
E
D
F
D
K
D
G
I
G
D
A
C
D
D
D
D
D
N
D
G
V
T
D
E
K
D
N
C
Q
L
L
F
N
P
R
Q
A
D
Y
--------
D
K
D
E
V
G
----
D
R
C
D
N
C
P
Y
V
H
N
P
A
Q
I
D
T
D
N
N
G
E
G
D
A
C
S
V
D
I
D
G
D
D
V
F
N
E
R
D
N
C
P
Y
V
Y
N
T
D
Q
R
D
T
D
G
D
G
V
G
D
H
C
D
N
C
P
L
V
H
N
P
D
Q
T
D
V
D
N
D
L
V
G
D
Q
C
D
--
N
N
--
E
D
I
D
D
D
G
H
Q
N
N
Q
D
N
C
------
P
Y
I
S
-
N
A
N
Q
A
D
H
D
R
D
G
Q
G
D
A
C
D
P
D
D
-
D
N
D
G
V
P
D
D
R
D
N
C
R
L
V
F
N
P
D
Q
E
D
L
D
----
G
D
G
R
G
D
I
C
K
D
D
F
D
N
D
-
N
I
P
D
I
D
D
V
C
P
E
N
N
A
I
S
E
T
D
-----
F
R
N
F
Q
M
V
P
L
-
D
P
K
G
T
T
Q
I
D
P
N
W
V
I
R
H
Q
G
K
E
L
V
----
Q
T
A
N
S
D
P
G
I
A
V
G
F
D
E
F
G
S
V
D
F
S
G
T
F
Y
V
N
T
D
R
D
D
D
Y
A
G
F
V
F
G
Y
Q
S
S
S
-----
R
F
Y
V
V
M
W
K
Q
V
-
T
Q
T
Y
W
E
D
Q
P
T
R
A
Y
G
Y
S
G
V
S
L
K
V
V
N
S
T
-
T
G
-------
T
----
G
-------
E
H
------
L
R
N
A
L
W
-------
H
T
G
N
T
P
G
Q
V
R
T
L
W
H
D
P
R
N
I
G
W
K
D
Y
T
A
Y
-
R
W
H
L
T
H
R
P
K
T
----
G
-------
Y
I
---
R
V
L
V
--
H
E
-
G
K
Q
V
M
A
D
S
G
P
I
Y
D
Q
T
Y
A
-
G
-
G
-
R
--
L
---
G
L
------
F
V
F
S
Q
E
-
M
V
--
Y
---------
F
-----------
S
----------
D
L
K
Y
E
C
R
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
39.94
11%
-150
- C5 -
3ODU
6
CXCR4_HUMAN (first)
A:
[49-238]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
L
P
T
I
Y
S
I
I
F
L
T
G
I
V
G
-----
N
G
L
V
I
L
V
M
G
Y
-
Q
K
K
L
R
S
M
T
D
K
Y
R
L
H
L
S
V
A
D
L
L
F
V
I
T
L
-
P
F
-------
W
----
A
V
D
A
V
A--
N
W
------
Y
F
G
N
F
L
-------
C
K
A
V
H
V
I
Y
T
V
N
L
Y
S
S
V
W
I
L
A
F
I
S
L
D
R
Y
-
L
A
I
V
H
A
T
N
S
Q
R
P
R
K
L
-------
L
A
---
E
K
V
V
--
Y
V
-
G
V
W
I
P
A
L
L
L
T
I
P
D
F
I
F
A
N
V
-
S
-
E
--
A
---
D
D
------
R
Y
I
C
D
R
-
F
Y
--
P
---------
N
-----------
D
L
W
V
V
V
F
Q
F
Q
H
I
M
V
G
L
I
L
P
G
I
V
I
L
S
C
Y
C
I
I
I
S
K
L
S
H
S
G
S
N
I
F
E
M
--------
L
---
R
I
D
E
G
L
R
L
-
K
I
Y
-
K
D
T
-
E
G
Y
Y
T
I
G
I
G
H
L
L
-
T
K
S
P
S
L
N
A
A
-
K
S
--------
E
-----------------
L
D
K
A
-
I
G
R
-
N
--
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
-
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
21
PsiBlast_CBE
39.81
39%
5
- C4 -
2BO2
2
AGRE2_HUMAN
B:
[20-95]
-------------------------------------------------
A
C
-
R
-
C
N
P
G
F
S
S
FSEIIT
T
P
------------
M
E
T
C
D
D
I
N
E
C
A
T
L
S
--
S
C
---
G
K
F
S
D
C
W
N
T
----
E
G
S
Y
D
C
V
-
C
S
P
G
Y
E
P
V
S
G
A
K
---
T
F
K
N
E
S
E
N
T
C
Q
-----
D
V
----
D
E
C
S
S
G
Q
H
Q
-----------
C
D
S
S
T
V
C
F
N
T
V
-
G
S
Y
S
C
R
C
R
P
G
W
K
P
R
H
G
I
P
N
N
Q
K
D
T
V
C
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
39.34
12%
-126
- C5 -
2RH1
6
ADRB2_HUMAN (first)
A:
[45-234]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
M
S
L
I
V
L
A
I
V
F
G
-----
N
V
L
V
I
T
A
I
A
K
-
F
E
R
L
Q
T
V
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
-------
F
G
---
A
A
H
I
L
M
K-
M
W
------
T
F
G
N
F
W
-------
C
E
F
W
T
S
I
D
V
L
C
V
T
A
S
I
E
T
L
C
V
I
A
V
D
R
Y
-
F
A
I
T
S
P
F
K
Y
Q
----
S
LLT
K
---
N
K
---
A
R
V
I
--
I
L
-
M
V
W
I
V
S
G
L
T
S
F
L
P
I
Q
M
H
-
W
-
Y
-
R
AT
H
---
Q
E
A
I
N
C
Y
A
E
E
T
C
C
D
F
F
T
--
N
Q
A
Y
A
I
----
A
-----------
S
----------
S
I
V
S
F
Y
V
P
L
V
I
M
V
F
V
Y
S
R
V
F
Q
E
A
K
R
Q
L
N
I
F
E
M
L
--------
R
---
I
D
E
G
L
R
L
K
-
I
Y
K
-
D
T
E
-
G
Y
Y
T
I
G
I
G
H
L
L
T
-
K
S
P
S
L
N
A
A
K
-
S
E
--------
L
-----------------
D
K
A
I
-
G
R
N
-
T
--
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
-
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
8
PsiBlast_PDB
38.26
35%
-68
- C4 -
1YO8
3
A:
[6-83]
-----------------------
C
L
S
N
--
P
C
F
P
G
---
A
Q
C
S
S
-
F
P
D
G
S
W
S
C
G
F
-
C
P
V
G
F
L
G
------
N
G
-------------
T
H
C
E
D
L
D
E
C
A
L
V
P
D
-
I
C
FST
S
K
V
P
R
C
V
N
T
----
Q
P
G
F
H
C
L
P
C
P
P
R
Y
R
G
N
Q
P
V
G
---
V
G
L
E
A
A
K
T
E
K
Q
-----
V
C
----
E
P
E
N
P
C
K
D
K
-----------
T
H
N
C
H
K
H
A
E
C
I
-
Y
L
G
H
F
S
D
P
M
Y
K
C
E
C
Q
T
G
Y
A
G
D
G
L
I
C
G
E
D
S
D
L
D
G
W
P
N
L
N
L
V
C
A
T
--------
N
A
T
Y
H
C
----
I
K
D
N
C
P
H
L
P
N
S
G
Q
E
D
F
D
K
D
G
I
G
D
A
C
D
D
D
D
D
N
D
G
V
T
D
E
K
D
N
C
Q
L
L
F
N
P
R
Q
A
D
Y
D
K
D
E
V
G
D
R
C
D
N
C
P
Y
V
H
N
P
A
Q
I
D
T
D
N
N
G
E
G
D
A
C
S
V
--
D
I
--
D
G
D
D
V
F
N
E
R
D
N
C
P
Y
V
------
Y
N
T
D
-
Q
R
D
T
D
G
D
G
V
G
D
H
C
D
N
C
P
L
V
H
-
N
P
D
Q
T
D
V
D
N
D
L
V
G
D
Q
C
D
N
N
E
D
I
D
D
----
D
G
H
Q
N
N
Q
D
N
C
P
Y
I
S
N
-
A
N
Q
A
D
H
D
R
D
G
Q
G
D
A
C
D
P
D
D
-----
D
N
D
G
V
P
D
D
R
-
D
N
C
R
L
V
F
N
P
D
Q
E
D
L
D
G
D
G
R
G
D
I
----
C
K
D
D
F
D
N
D
N
I
P
D
I
D
D
V
C
P
E
N
N
A
I
S
E
T
D
F
R
N
F
Q
M
V
P
L
D
P
K
G
T
T
Q
I
D
P
-----
N
W
V
I
R
H
Q
G
K
E
-
L
V
Q
T
A
N
S
D
P
G
I
A
V
G
F
D
E
F
G
S
V
D
F
S
G
T
-
F
Y
-------
V
----
N
-------
T
D
------
R
D
D
D
Y
A
-------
G
F
V
F
G
Y
Q
S
S
S
R
F
Y
V
V
M
W
K
Q
V
T
Q
T
Y
W
E
D
-
Q
P
T
R
A
Y
G
Y
S
G
----
V
-------
S
L
---
K
V
V
N
--
S
T
-
T
G
T
G
E
H
L
R
N
A
L
W
H
T
G
N
T
-
P
-
G
-
Q
--
V
---
R
T
------
L
W
H
D
P
R
-
N
I
--
G
---------
W
-----------
K
----------
D
Y
T
A
Y
R
W
H
L
T
H
R
P
K
T
G
Y
I
R
V
L
V
H
E
G
K
Q
V
M
A
D
S
G
--------
P
---
I
Y
D
Q
T
Y
A
G
-
G
R
L
-
G
L
F
-
V
F
S
Q
E
M
V
Y
F
S
D
L
-
K
Y
E
C
R
D
--------------------------------------------------------------------------------------
2
PsiBlast_PDB
38.23
39%
15
- C4 -
2BO2
2
AGRE2_HUMAN
A:
[20-95]
-------------------------------------------------
A
C
-
R
-
C
N
P
G
F
S
S
FSEIIT
T
P
------------
M
E
T
C
D
D
I
N
E
C
A
T
L
S
K
V
S
C
---
G
K
F
S
D
C
W
N
T
----
E
G
S
Y
D
C
V
-
C
S
P
G
Y
E
P
V
S
G
A
K
---
T
F
K
N
E
S
E
N
T
C
Q
-----
D
V
----
D
E
C
S
S
G
Q
H
Q
-----------
C
D
S
S
T
V
C
F
N
T
V
-
G
S
Y
S
C
R
C
R
P
G
W
K
P
R
H
G
I
P
N
N
Q
K
D
T
V
C
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
37.88
9%
-134
- C5 -
3UON
2
ACM2_HUMAN (first)
A:
[28-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
A
G
S
L
S
L
V
T
I
I
G
-----
N
I
L
V
M
V
S
I
K
V
-
N
R
H
L
Q
T
V
N
N
Y
F
L
F
S
L
A
C
A
D
L
I
I
G
V
F
S
-
M
N
-------
L
Y
T
L
Y
T
V
I
G----
Y
W
------
P
L
G
P
V
V
-------
C
D
L
W
L
A
L
D
Y
V
V
S
N
A
S
V
M
N
L
L
I
I
S
F
D
R
Y
-
F
C
V
T
K
P
L
T
Y
P
----
V
KRT
T
---
K
M
---
A
G
M
M
--
I
A
-
A
A
W
V
L
S
F
I
L
W
A
P
A
I
L
F
W
Q
F
-
I
V
G
VR
T
---
V
E
------
D
G
E
C
Y
I
-
Q
F
--
F
---------
S
N
A
A
V
T
F
G
----
T
----------
A
I
A
A
F
Y
L
P
V
I
I
M
T
V
L
Y
W
H
I
S
R
A
S
K
S
R
I
N
I
F
E
M
L
--------
R
---
I
D
E
G
L
R
L
K
-
I
Y
K
-
D
T
E
-
G
Y
Y
T
I
G
I
G
H
L
L
T
-
K
S
P
S
L
N
A
A
K
-
S
E
--------
L
-----------------
D
K
A
I
-
G
R
N
-
T
--
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
-
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
20
PsiBlast_PDB
36.77
28%
47
- C4 -
1X7A
-
?
L:
[51-121]
-----------------------
C
E
P
N
--
P
C
L
N
G
---
G
L
C
-
K
-
D
D
I
N
S
Y
E
C
-
W
-
C
Q
V
G
F
E
G
------
K
N
---------------
C
E
L
D
A
T
C
N
I
K
N
G
-
R
C
---
K
Q
F
C
K
-
T
G
A
----
D
S
K
V
L
C
S
-
C
T
T
G
Y
R
L
A
P
D
Q
K
---
S
C
K
P
A
V
P
F
P
C
G
-----
R
V
----
S
V
S
H
S
P
T
T
L
-----------
T
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------