@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : FZD10_HUMAN: (2016-01-09 )
MQRPGPRLWLVLQVMGSCAAISSMDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCDNPGKFHHVEKSASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQVCSRRLKKKSRRKPASVITSGGIYKKAQHPQKTHHGKYEIPAQSPTCV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.....-...80........90.......-.100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250-.......260.......270.......280...-.-...290.......300.......310.......320.......330..---.....340.......350.......360.......370.......380.......390.......400.......410.......420......--.430.......440.......450.......460.......470-.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQRPG
P
R
L
W
L
V
L
Q
V
MG
S
C
A
A
I
S
SMDMERPGDGKC
Q
P
I
EIPMCKDIGYNMTRM
P
N
LMGHE
N
Q
R
E
A
A
I
Q
L
H
EFA
P
L
V
E
-YGC
H
G
H
L
R
F
F
L
C
S
L
Y
A
P
M
C
T
E
Q-VSTP
I
P
A
C
R
V
M
C
E
Q
ARLK
C
S
P
I
M
E
QFNFKWPDSL
D
C
RKLPNKNDP
N
Y
L
C
M
EAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCDNPGK
F
H
H
VEKSASCAPLCTPG
V
D
V
Y
WSRED
K
R
F
A
V
V
W
L
A
I
W
A
V
L
C
F
F
S
S
A
F
T
V
L
T
F
LI
D
-
P
A
RFRYPERP
I
I
F
L
S
M
C
Y
C
V
Y
S
V
G
Y
L
I
R
L
FAGA-E-SIACDRDS
G
Q
L
Y
V
I
Q
EGLEST
G
C
T
L
V
F
L
V
L
Y
Y
F
G
M
A
S
S
L
W
W
V
V
L
T
L
T
W
---
F
L
A
A
G
K
KWGH
E
A
IEANS
S
Y
F
H
L
A
A
W
A
I
P
A
V
K
T
I
L
I
L
V
M
R
R
VAGDE
L
T
G
V
C
Y
VGSM
D
V
N
A
LT
G
F
V
L
I
P
L
A
C
Y
L
V
I
G
T
S
F
I
L
S
G
F
V
A
L
F
H
I
R
R
V
M
K
--TGGE
N
T
D
K
L
E
K
L
M
V
R
I
G
L
F
S
V
L
Y
TV
P
A
T
C
V
I
A
C
Y
F
Y
E
R
L
N
M
D
Y
W
-
K
I
L
A
A
Q
H
KCKMNNQT
K
T
L
D
C
L
M
A
ASI
P
A
V
E
I
F
M
V
K
I
F
M
L
L
V
V
GITS
G
M
W
I
W
T
S
K
T
L
Q
S
W
Q
Q
V
C
S
R
R
L
K
K
K
SRRKPA
S
V
ITSGGIYKKAQHPQKTHHG
K
Y
EIPAQSPTCV
44
Fugue
76.04
23%
-93
- C5 -
4JKV
10
C562_ECOLX (first)
A:
[2-470]
--------------------------------------------------------
G
T
A
D
L
E
D
N
W
E
T
L
N
D
N
L
K
V
I
E
K
A
D
N
A
A
Q
V
K
D
A
L
T
K
M
R
A
A
A
L
D
A
Q
-
K
A
T
P
----
P
K
L
E
D
K
S
P
D
S
P
E
M
K
D
F
R
H
G
F
D
I
L
V
G
Q
I
D
D
A
L
K
L
A
N
E
G
K
V
K
E
A
Q
A
A
A
E
Q
L
K
T
T
R
N
A
Y
I
Q
K
Y
L
S
G
Q
C
E
V
P
L
V
R
T
D
N
----------------
P
K
S
W
Y
E
D
V
E
G
C
G
I
Q
C
Q
---
N
P
L
F
T
E
A
E
H
Q
D
M
H
S
Y
I
A
A
F
G
A
V
T
G
L
C
T
L
F
T
L
A
T
F
V
A
D
W
R
N
S
N
R
Y
P
A
V
I
L
F
Y
V
N
A
C
F
F
V
G
S
I
G
W
L
A
Q
F
M
D
G
A
R
R
-
E
I
V
C
R
A
D
G
T
M
R
L
G
E
P
T
S
N
E
T
L
S
C
V
I
I
F
V
I
V
Y
Y
A
L
M
A
G
V
V
W
F
V
V
L
T
Y
A
W
---
H
T
S
-
F
K
A
L
G
T
T
Y
Q
P
G
K
T
S
Y
F
H
L
L
T
W
S
L
P
F
V
L
T
V
A
I
L
A
V
A
Q
V
D
G
D
S
V
S
G
I
C
F
V
G
Y
K
N
Y
R
Y
R
A
G
F
V
L
A
P
I
G
L
V
L
I
V
G
G
Y
F
L
I
R
G
V
M
T
L
F
S
I
K
S
N
H
P
GL
L
S
E
K
A
A
S
K
I
N
E
T
M
L
R
L
G
I
F
G
F
L
A
F
G
F
V
L
I
T
F
S
C
H
F
Y
D
F
F
N
Q
A
E
W
E
R
S
F
R
D
Y
V
L
C
Q
A
N
C
E
I
K
--------
N
R
P
S
L
L
V
E
K
I
N
L
F
A
M
F
G
T
G
I
A
M
S
T
W
V
W
T
K
A
T
L
L
I
W
R
R
T
W
C
---------------------------------------------
8
PsiBlast_PDB
70.40
27%
-131
- C5 -
4N4W
6
SMO_HUMAN
A:
[121-471]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
P
K
S
W
Y
--
E
D
V
E
G
C
G
I
Q
C
Q
N
P
L
F
T
E
A
E
H
Q
D
M
H
---
S
Y
I
A
A
F
G
A
V
T
G
L
C
T
L
F
T
L
A
T
F
V
A
D
W
R
N
S
N
R
Y
P
A
V
I
L
F
Y
V
N
A
C
F
F
V
G
S
I
G
W
L
A
Q
F
M
D
G
A
-
R
R
E
I
V
C
R
A
D
G
T
M
R
L
G
E
P
T
S
N
E
T
L
S
C
V
I
I
F
V
I
V
Y
Y
A
L
M
A
G
V
V
W
F
V
V
L
T
Y
A
W
H
T
S
F
K
A
L
G
T
T
--
Y
Q
P
L
S
G
K
T
S
Y
F
H
L
L
T
W
S
L
P
F
V
L
T
V
A
I
L
A
V
A
Q
V
D
G
D
S
V
S
G
I
C
F
V
G
Y
K
N
Y
R
Y
R
A
G
F
V
L
A
P
I
G
L
V
L
I
V
G
G
Y
F
L
I
R
G
V
M
T
L
F
S
I
K
S
N
H
P
GL
L
S
E
---
S
K
I
N
E
T
M
L
R
L
G
I
F
G
F
L
A
F
G
F
V
L
I
T
F
S
C
H
F
Y
D
F
F
N
Q
A
E
W
-
E
R
S
F
R
D
Y
V
L
C
Q
A
------
D
C
E
I
-
K
N
R
P
S
L
L
V
E
K
I
N
L
F
A
M
F
G
T
G
I
A
M
S
T
W
V
W
T
K
A
T
L
L
I
W
R
R
T
W
C
R
L
T
------------------------------------------
7
PsiBlast_PDB
70.26
27%
-136
- C5 -
4JKV
10
C562_ECOLX (first)
A:
[121-470]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
P
K
S
W
Y
--
E
D
V
E
G
C
G
I
Q
C
Q
N
P
L
F
T
E
A
E
H
Q
D
M
H
---
S
Y
I
A
A
F
G
A
V
T
G
L
C
T
L
F
T
L
A
T
F
V
A
D
W
R
N
S
N
R
Y
P
A
V
I
L
F
Y
V
N
A
C
F
F
V
G
S
I
G
W
L
A
Q
F
M
D
G
A
-
R
R
E
I
V
C
R
A
D
G
T
M
R
L
G
E
P
T
S
N
E
T
L
S
C
V
I
I
F
V
I
V
Y
Y
A
L
M
A
G
V
V
W
F
V
V
L
T
Y
A
W
H
T
S
F
K
A
L
G
T
T
--
Y
Q
P
--
G
K
T
S
Y
F
H
L
L
T
W
S
L
P
F
V
L
T
V
A
I
L
A
V
A
Q
V
D
G
D
S
V
S
G
I
C
F
V
G
Y
K
N
Y
R
Y
R
A
G
F
V
L
A
P
I
G
L
V
L
I
V
G
G
Y
F
L
I
R
G
V
M
T
L
F
S
I
K
S
N
H
P
GL
L
S
E
K
A
A
S
K
I
N
E
T
M
L
R
L
G
I
F
G
F
L
A
F
G
F
V
L
I
T
F
S
C
H
F
Y
D
F
F
N
Q
A
E
W
-
E
R
S
F
R
D
Y
V
L
C
Q
A
N
------
C
E
I
-
K
N
R
P
S
L
L
V
E
K
I
N
L
F
A
M
F
G
T
G
I
A
M
S
T
W
V
W
T
K
A
T
L
L
I
W
R
R
T
W
C
---------------------------------------------
4
PsiBlast_PDB
66.55
50%
-124
- C6 -
5BQE
3
FZD4_HUMAN
C:
[5-126]
-------------------------------
R
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
-
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
-
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
66.30
51%
-121
- C6 -
5CM4
2
?
A:
[5-125]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
65.40
50%
-120
- C6 -
5BPB
2
FZD4_HUMAN
B:
[6-126]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
E
L
E
V
L
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
64.77
51%
-122
- C6 -
5CM4
2
?
B:
[5-125]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
64.77
50%
-119
- C6 -
5BPQ
1
FZD4_HUMAN
D:
[6-124]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
64.58
50%
-117
- C6 -
5BPQ
1
FZD4_HUMAN
B:
[6-124]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
64.40
50%
-119
- C6 -
5BPQ
1
FZD4_HUMAN
A:
[6-124]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
64.09
52%
-117
- C6 -
5CL1
2
?
D:
[15-131]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.09
52%
-122
- C6 -
5CL1
2
?
C:
[15-131]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
64.05
50%
-114
- C6 -
5BPB
1
FZD4_HUMAN
D:
[5-126]
-------------------------------
R
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
E
E
V
P
L
P
H
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
63.81
50%
-117
- C6 -
5BPB
1
FZD4_HUMAN
A:
[6-124]
--------------------------------
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_CBE
63.70
50%
-119
- C6 -
5BPQ
1
FZD4_HUMAN
C:
[7-124]
---------------------------------
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.77
50%
-117
- C6 -
5BQC
3
FZD4_HUMAN
B:
[5-126]
-------------------------------
R
R
C
D
P
I
R
I
S
M
C
Q
N
L
G
Y
N
V
T
K
M
P
N
L
V
G
H
E
L
Q
T
D
A
E
L
Q
L
T
T
F
T
P
L
I
Q
-
Y
G
C
S
S
Q
L
Q
F
F
L
C
S
V
Y
V
P
M
C
T
E
K
-
I
N
I
P
I
G
P
C
G
G
M
C
L
S
V
K
R
R
C
E
P
V
L
K
E
F
G
F
A
W
P
E
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
M
C
M
E
G
P
G
D
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
62.59
45%
-108
- C6 -
1IJY
-
FZD8_MOUSE
A:
[5-126]
------------------------------
E
L
A
C
Q
E
I
T
V
P
L
C
K
G
I
G
Y
E
Y
T
Y
M
P
N
Q
F
N
H
D
T
Q
D
E
A
G
L
E
V
H
Q
F
W
P
L
V
E
-
I
Q
C
S
P
D
L
K
F
F
L
C
S
M
Y
T
P
I
C
L
E
D
-
Y
K
K
P
L
P
P
C
R
S
V
C
E
R
A
K
A
G
C
A
P
L
M
R
Q
Y
G
F
A
W
P
D
R
M
R
C
D
R
L
P
E
Q
G
N
P
D
T
L
C
M
D
Y
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
62.57
46%
-105
- C6 -
1IJY
-
FZD8_MOUSE
A:
[5-126]
------------------------------
E
L
A
C
Q
E
I
T
V
P
L
C
K
G
I
G
Y
E
Y
T
Y
M
P
N
Q
F
N
H
D
T
Q
D
E
A
G
L
E
V
H
Q
F
W
P
L
V
E
-
I
Q
C
S
P
D
L
K
F
F
L
C
S
M
Y
T
P
I
C
L
E
D
Y
K
-
K
P
L
P
P
C
R
S
V
C
E
R
A
K
A
G
C
A
P
L
M
R
Q
Y
G
F
A
W
P
D
R
M
R
C
D
R
L
P
E
Q
G
N
P
D
T
L
C
M
D
Y
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
62.43
45%
-108
- C6 -
1IJY
-
FZD8_MOUSE
A:
[5-126]
------------------------------
E
L
A
C
Q
E
I
T
V
P
L
C
K
G
I
G
Y
E
Y
T
Y
M
P
N
Q
F
N
H
D
T
Q
D
E
A
G
L
E
V
H
Q
F
W
P
L
V
E
-
I
Q
C
S
P
D
L
K
F
F
L
C
S
M
Y
T
P
I
C
L
E
D
-
Y
K
K
P
L
P
P
C
R
S
V
C
E
R
A
K
A
G
C
A
P
L
M
R
Q
Y
G
F
A
W
P
D
R
M
R
C
D
R
L
P
E
Q
G
N
P
D
T
L
C
M
D
Y
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.94
49%
-115
- C6 -
4F0A
2
FZD8_MOUSE
A:
[8-124]
---------------------------------
C
Q
E
I
T
V
P
L
C
K
G
I
G
Y
N
Y
T
Y
M
P
N
Q
F
N
H
D
T
Q
D
E
A
G
L
E
V
H
Q
F
W
P
L
V
E
-
I
Q
C
S
P
D
L
K
F
F
L
C
S
M
Y
T
P
I
C
L
E
D
-
Y
K
K
P
L
P
P
C
R
S
V
C
E
R
A
K
A
G
C
A
P
L
M
R
Q
Y
G
F
A
W
P
D
R
M
R
C
D
R
L
P
E
Q
G
N
P
D
T
L
C
M
D
A
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------