@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : GHRHR_HUMAN: (2016-01-09 )
MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC
Atome Classification :
(20 SA)
----------------.........10........20.......-----.30........40.---...---..------.---.--50-----.........60--------........70........80......-.--.--90........100.......110..---.....120.......--130........140.......150.......160----.......170.......180---.-....--..-.190.......200------........210.......220..------.....230-------.......-----.--240........250..---.....260...-.---.----..270.....---..----------280.-----.----.......290.......300..------.....310.--------.....--.320.......330.......340.......--350--.------------..------...----...360.......370....-------...380.......390.......400.......410.......420.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------MDRRMWG
A
H
V
F
C
V
LS
P
L
P
T
V
L
GHMHPE
C
-----
D
F
I
T
Q
LRE
D
E
S
A
C
L
---
Q
A
A
---
E
E------M---P--N------TTLGCPATWD
G
--------
L
L
C
W
PTAGSG
E
W
V
T
LP
C
P
D
F
F
S
H
FSS-E--S--GAVKR
D
C
T
ITGWSEPFPPYPVACPV---
P
L
E
L
L
AEEESY
F
S
T
V
--
K
I
-
I
Y
TVGH
S
I
S
I
V
A
L
F
V
A
I
T
I
L
V
A
L
R
R
LHCP
R
N
----
Y
V
H
T
Q
L
F
T
T
F
I
L
K
A
G
A
V
F
L
----
K
-
D
A
AL--FH-SDDTDHC
S
F
S
T
V
L
-------
C
K
V
S
V
A
A
S
H
F
A
T
M
T
N
F
S
W
L
L
A
E
A
------
V
Y
L
N
C
L
L--------ASTSPSS-----
R
--
R
-
A
F
W
W
L
V
LAGWG
L
P
V
---
L
F
TG
T
W
V
S
C
K
L
-
A
---
F
----
E
D
I
A
C
WDLDD---TS----------
P
--
Y
-----
W
----
W
I
I
KG
P
I
V
L
S
VGV
N
F
G
L
F
L
N
I
I
------
R
I
L
V
R
KLEP--------AQGSL--HTQS
Q
Y
W
R
LSK
S
T
L
F
L
I
P
L
F
G
I
H
Y
I
I
F
NFLP--D----N------------AG------
L
G
I
----
R
L
P
L
E
LGL
G
S
F
Q
G
F
I
V
A
I
L
Y
-------
C
FL
N
Q
E
V
R
T
E
I
S
R
KWHGHDPE
L
L
P
A
W
RTRAKWTTPS
R
S
A
A
K
V
L
T
SMC
1
PsiBlast_PDB
85.34
38%
-134
- C3 -
4L6R
1
C562_ECOLX (first)
A:
[111-394]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
V
Q
K
E
V
A
K
M
Y
S
S
F
--
Q
V
-
M
Y
T
V
G
Y
S
L
S
L
G
A
L
L
L
A
L
A
I
L
G
G
L
S
K
L
H
C
T
R
N
----
A
I
H
A
N
L
F
A
S
F
V
L
K
A
S
S
V
L
V
----
I
-
D
G
L
L
R
T---------------
L
SDGAVA
G
C
R
V
A
A
V
F
M
Q
Y
G
I
V
A
N
Y
C
W
L
L
V
E
G
------
L
Y
L
H
N
L
L
--------
G
L
A
T
L
P
E
-----
R
--
S
-
F
F
S
L
Y
L
G
I
G
W
G
A
P
M
---
L
F
V
V
P
W
A
V
V
K
C
-
L
---
F
----
E
N
V
Q
C
W
T
S
N
D
---
N
M
----------
G
--
F
-----
W
----
W
I
L
R
F
P
V
F
L
A
I
L
I
N
F
F
I
F
V
R
I
V
------
Q
L
L
V
A
K
L
R
A
--------
R
Q
--
M
--
H
H
T
D
Y
K
F
R
L
A
K
S
T
L
T
L
I
P
L
L
G
V
H
E
V
V
F
A
F
V
T
--
D
----
E
------------
H
A
------
Q
G
T
L
R
S
A
K
L
F
F
D
L
F
L
S
S
F
Q
G
L
L
V
A
V
L
Y
-------
C
F
L
N
K
E
V
Q
S
E
L
R
R
R
W
H
R
W
R
L
G
K
V
L
W
E
E
R
N
------------------
21
PsiBlast_CBE
70.79
96%
-86
- C4 -
2XDG
4
GHRHR_HUMAN
B:
[2-90]
-----------------------------------------------------
M
L
R
E
D
E
S
A
C
L
---
Q
A
A
---
E
E
------
M
---
P
--
Q
------
T
T
L
G
C
P
A
T
W
D
G
--------
L
L
C
W
P
T
A
G
S
G
E
W
V
T
L
P
C
P
D
F
F
S
H
F
S
S
-
E
--
S
--
G
A
V
K
R
D
C
T
I
T
G
W
S
E
P
F
P
P
Y
P
V
A
C
P
V
---
P
L
E
L
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.55
96%
-79
- C4 -
2XDG
2
GHRHR_HUMAN
A:
[2-90]
-----------------------------------------------------
M
L
R
E
D
E
S
A
C
L
---
Q
A
A
---
E
E
------
M
---
P
--
Q
------
T
T
L
G
C
P
A
T
W
D
G
--------
L
L
C
W
P
T
A
G
S
G
E
W
V
T
L
P
C
P
D
F
F
S
H
F
S
S
-
E
--
S
--
G
A
V
K
R
D
C
T
I
T
G
W
S
E
P
F
P
P
Y
P
V
A
C
P
V
---
P
L
E
L
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
66.12
34%
-111
- C3 -
4K5Y
2
CRFR1_HUMAN
C:
[284-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
M
F
I
C
I
G
W
G
V
P
F
---
P
I
I
V
A
W
A
I
G
K
L
-
Y
---
Y
----
D
N
E
K
C
W
A
G
K
R
---
P
G
----------
V
--
Y
-----
T
D---
Y
I
Y
Q
G
P
M
A
L
V
L
L
I
N
F
I
F
L
F
N
I
V
------
R
I
L
M
T
K
L
R
A
--------
S
T
T
S
E
--
T
I
Q
A
R
--
K
A
V
K
A
T
L
V
L
L
P
L
L
G
I
T
Y
M
L
A
F
V
N
P
GE
D
----
E
------------
V
S
------
R
V
V
----
F
I
Y
F
N
A
F
L
E
S
F
Q
G
F
F
V
S
V
F
A
-------
C
F
L
N
-------------------------------------------
68
Fugue
63.23
18%
-110
- C3 -
4K5Y
7
CRFR1_HUMAN (first)
A:
[13-423]
H
Y
H
V
A
A
I
I
N
Y
L
G
H
C
I
S
L
V
A
L
L
V
A
F
V
L
F
L
R
A
R
S
I
R
C
L
R
N
I
I
H
A
N
L
-----
I
A
A
F
I
L
R
N
A
T
W
F
V
V
---
Q
L
T
M
S
P
E
V
------
H
---
Q
--
S
------
N
V
G
W
C
R
L
V
T
A
A
Y
N
Y
F
H
V
T
N
F
F
W
M
F
G
E
G
C
Y
L
H
T
A
I
V
L
T
N
I
F
E
M
L
R
I
-
D
--
E
--
G
L
-----
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
---
L
L
T
K
S
P
S
L
S
V
A
K
S
E
L
D
K
A
I
-
G
R
N
S
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
----
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
S
A
L
I
----
N
-
M
V
F
Q
--
M
G
-
E
T
G
V
A
G
F
T
N
S
L
R
M
-------
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
------
N
R
A
K
R
V
I
--------
A
T
F
R
T
G
T
W
D
A
Y
D
R
--
L
-
R
A
W
M
F
I
C
I
G
W
G
V
P
F
---
P
I
I
V
A
W
A
I
G
K
L
-
Y
---
Y
----
D
N
E
K
C
W
A
G
K
R
---
P
G
----------
V
--
Y
T----
D
----
Y
I
Y
Q
G
P
M
A
L
V
L
L
I
N
F
I
F
L
F
N
I
V
------
R
I
L
M
T
K
L
R
A
--------
S
T
T
S
E
--
T
I
Q
A
R
--
K
A
V
K
A
T
L
V
L
L
P
L
L
G
I
T
Y
M
L
A
F
--
V
--
N
----
E
------------
V
S
------
R
V
V
----
F
I
Y
F
N
A
F
L
E
S
F
Q
G
F
F
V
S
V
F
A
-------
C
F
L
N
S
------------------------------------------
45
HHSearch
62.42
87%
-48
- C4 -
2XDG
2
GHRHR_HUMAN
A:
[2-85]
-----------------------------------------------------
M
L
R
E
D
E
S
A
C
L
---
Q
A
A
---
E
E
------
M
---
P
--
Q
------
T
T
L
G
C
P
A
T
W
D
G
--------
L
L
C
W
P
T
A
G
S
G
E
W
V
T
L
P
C
P
D
F
F
S
H
F
S
S
-
E
--
S
--
G
A
V
K
R
D
C
T
I
T
G
W
S
E
P
F
P
P
-
Y
P
V
A
C
P
---
V
P
L
E
L
L
A
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
Fugue
61.53
17%
-110
* C2 *
3NOY
2
ISPG_AQUAE
A:
[10-358]
------------MIQK
R
K
T
R
Q
I
R
V
G
N
V
K
I
G
G
D
A
P
I
V
V
Q
S
M
-----------
T
S
T
K
T
H
D
V
E
A
T
L
---
N
Q
I
---
K
R
------
L
---
Y
--
E
------
A
--
G
C
------------------------
E
I
V
R
V
A
V
P
H
-----------------
K
E
D
V
E
A
L
E
E
I
V
K
K
S
P
M
P
V
I
A
D
I
H
F
A
P
S
Y
A
F
L
S
M
E
K
G
V
H
G
I
--
R
I
N
P
G
N
I
G
K
E
E
I
V
R
E
I
V
E
E
A
K
R
R
G
V
A
V
R
I
G
V
N
S
G
----
S
L
E
K
D
L
L
E
K
Y
-
G
Y
P
S
A
E
A
L
----
A
-
E
S
A
L
--
R
W
-
S
E
K
F
E
K
W
G
F
T
N
---------
Y
K
V
S
I
K
G
S
D
V
L
Q
N
V
R
A
N
L
I
F
A
E
R
------
T
D
V
P
L
H
I
G
I
T
EAGMG
T
K
G
I
I
K
S
-----
S
--
V
-
G
I
G
I
L
L
Y
M
G
I
G
D
T
V
R
V
S
L
T
D
D
P
V
V
E
V
E
T
-
A
---
Y
----
E
I
L
K
S
L
G
L
R
R
---
R
G
----------
V
-------------
E
I
V
A
C
P
T
C
G
R
I
E
V
D
---
L
P
K
V
V
------
K
E
V
Q
E
K
L
S
G
--------
V
K
T
P
L
-----------------
K
V
A
V
M
G
C
-----------
V
----
V
------------
N
A
------
I
G
E
----
A
R
E
A
D
I
G
L
A
C
G
R
G
----
F
A
W
-------
L
F
K
H
G
K
P
I
K
K
V
D
------
E
S
E
M
V
D
E
L
L
K
E
I
Q
N
---------------
4
PsiBlast_PDB
60.18
38%
-68
- C4 -
2X57
-
VIPR2_HUMAN
A:
[27-109]
--------------------------------------------------
F
H
L
E
I
Q
E
E
E
T
K
C
A
---
E
L
L
---
R
S
------
Q
---
T
--
E
------
K
H
K
A
C
S
G
V
W
D
N
--------
I
T
C
W
R
P
A
N
V
G
E
T
V
T
V
P
C
P
K
V
F
S
N
F
Y
S
-
K
--
A
--
G
N
I
S
K
N
C
T
S
D
G
W
S
E
T
F
P
D
F
V
D
A
C
G
Y
---
S
D
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
Fugue
58.57
22%
-120
- C2 -
5CMN
1
?
E:
[3-260]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
P
G
L
LKGV
Y
Q
S
E
H
L
F
E
S
D
-
H
Q
S
G
A
W
C
K
DPLQ
A
-
S
D
K
I
--
Y
Y
-
M
P
W
T
P
Y
R
T
--
D
T
L
-------
T
E
Y
S
S
K
D
D
F
I
A
G
R
P
T
T
T
Y
K
L
P
H
R
VDGTGF
V
V
Y
D
G
A
L
--------
F
F
N
K
E
R
T
-----
R
--
N
-
I
V
K
F
D
L
R
T
R
--------
I
K
S
G
E
A
I
----------------
I
A
N
A
N
Y
H
D
---
T
S
----------
P
--
Y
-----
R
----
W
G
G
K
S
D
I
D
L
A
V
D
E
N
-
G
L
W
V
I
Y
A
TEQNNG
K
I
V
I
S
Q
L
N
P
--------
Y
T
L
R
I
EG
T
W
D
T
A
Y
D
K
R
S
A
S
N
A
F
M
I
--
C
G
I
L
Y
V
V
K
S
N
K
I
--
D
YIY-
N
------------
T
D
------
Q
S
K
----
D
S
L
V
D
V
P
F
P
N
S
Y
Q
Y
I
A
A
V
D
Y
NPRDNLL
Y
V
W
N
N
Y
H
V
V
K
Y
S
L
D
F
--------------------------------
56
HHSearch
57.09
15%
-111
- C3 -
2KS9
1
NK1R_HUMAN
A:
[36-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
-
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
----
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
T
V
----
V
-
N
F
T
Y
--
A
V
H
N
E
W
Y
----
Y
G
L
F
Y
-------
C
K
F
H
N
F
F
P
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
------
F
D
R
Y
M
A
I
--------
I
H
P
L
Q
P
R
-----
L
S
A
T
-
A
T
K
V
V
I
C
V
I
W
V
L
A
L
---
L
L
A
F
P
Q
G
Y
Y
S
T
-
T
---
E
TMP-
S
R
V
V
C
M
I
E
W
P
EHP
N
K
IY
E
K
------
V
--
Y
H
I
C
V
T
V
----
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
I
T
L
W
------
A
S
E
-
I
P
G
D
S
--------
S
D
R
Y
H
--
E
Q
V
S
A
K
R
K
V
V
K
M
M
I
V
V
V
C
T
F
A
I
C
W
L
P
F
H
I
F
F
--
L
----
L
P
Y
I
N--------
P
D
LYLKKF
I
Q
Q
----
V
Y
L
A
I
M
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
-------
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
R
C
C
P
F
I
S
A
G
D
Y
E
G
L
E
M
K
S
T
R
Y
L
Q
T
Q
G
S
V
Y
K
V
S
49
HHSearch
56.16
12%
-112
* C3 *
2Z73
5
OPSD_TODPA
A:
[34-333]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
S
L
--
G
I
-
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
----
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
----
P
L
M
T
I
S
C
-
F
L
-
K
K
W
I
----
F
G
F
A
A
-------
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
------
I
D
R
Y
N
V
I
--------
G
R
P
M
A
A
S
K
K
M
S
-
H
--
R
-
R
A
F
I
M
I
I
F
V
W
L
W
S
V
---
L
W
A
I
G
P
I
F
G
W
G
A
Y
T
L
E
G
----
V
L
C
N
C
S
F
D
Y
I
---
S
R
D
S
T
T
R
S
N
I
L
C
M
--
F
-----
I
----
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
M
S
V
S
------
N
H
E
K
E
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
--
A
G
A
N
A
E
M
R
L
A
K
I
S
I
V
I
V
S
Q
F
L
L
S
W
S
P
Y
A
V
V
A
--
L
----
L
A
Q
FGPLE-----
W
V
------
T
P
Y
----
A
A
Q
L
P
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
-------
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
P
W
V
L
T
C
C
Q
F
D
D
K
E
T
E
D
D
K
D
A
E
T
E
I
P
A
G
E
----
65
Fugue
55.37
33%
-64
- C4 -
2JOD
-
PACR_HUMAN
A:
[17-122]
-----------------------------------
M
G
S
M
A
H
S
D
G
-----
I
----
F
K
K
E
Q
A
M
C
L
---
E
K
I
---
Q
R
------
A
---
N
--
E
L
MGFND
S
S
P
G
C
P
G
M
W
D
N
--------
I
T
C
W
K
P
A
H
V
G
E
M
V
L
V
S
C
P
E
L
F
R
I
F
N
P
-
D
--
Q
DM
G
V
V
S
R
N
C
T
E
D
G
W
S
E
P
F
P
H
Y
F
D
A
C
G
F
---
D
E
Y
E
S
E
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
54.98
33%
-54
- C4 -
3N94
1
MALE_ECOLI
A:
[370-468]
------------------------------------------
A
A
-----
A
E
F
A
I
F
K
K
E
Q
A
M
C
L
---
E
K
I
---
Q
R
A
N
E
L
M
G
F
---
N
--
D
------
S
S
P
G
C
P
G
M
W
D
N
--------
I
T
C
W
K
P
A
H
V
G
E
M
V
L
V
S
C
P
E
L
F
R
I
F
N
P
-
D
QD
M
--
G
V
V
S
R
N
C
T
E
D
G
W
S
E
P
F
P
H
-
Y
F
D
A
C
G
---
F
D
E
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
54.97
40%
-93
- C4 -
3N94
1
MALE_ECOLI
A:
[377-463]
------------------------------------------------------
F
K
K
E
Q
A
M
C
L
E
K
I
Q
R
A
---
N
E
------
L
M
G
F
N
--
D
------
S
S
P
G
C
P
G
M
W
D
N
--------
I
T
C
W
K
P
A
H
V
G
E
M
V
L
V
S
C
P
E
L
F
R
I
F
N
P
-
D
--
Q
DM
G
V
V
S
R
N
C
T
E
D
G
W
S
E
P
F
P
H
Y
F
D
A
C
G
F
---
D
E
Y
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
54.19
16%
-112
- C3 -
2LNL
-
CXCR1_HUMAN
A:
[42-322]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
--
I
I
-
A
Y
A
L
V
F
L
L
S
L
L
G
N
S
L
V
M
L
V
I
L
Y
S
R
V
G
R
S
V
T
D
----
V
Y
L
L
N
L
A
L
A
D
L
L
F
A
L
T
L
P
I
----
W
-
A
A
S
K
--
V
--
N
G
W
I
----
F
G
T
F
L
-------
C
K
V
V
S
L
L
K
E
V
N
F
Y
S
G
I
L
L
L
A
C
I
S
------
V
D
R
Y
L
A
I
--------
V
H
A
T
R
T
L
-----
T
Q
K
R
H
L
V
K
F
V
C
L
G
C
W
G
L
S
M
---
N
L
S
L
P
F
F
L
F
R
Q
-
A
---
Y
HPNN
S
S
P
V
C
Y
E
V
L
G
---
N
D
TAKW------
R
MV
L
R----
I
LPHT
F
G
F
I
V
P
L
F
V
M
L
F
C
Y
----
G
F
T
L
------
R
T
L
F
K
A
-------------------
H
M
G
Q
K
H
R
A
M
R
V
I
F
A
V
V
L
I
F
L
L
C
W
L
P
Y
N
L
V
L
--
L
A
D
T
L
M
RTQVIQE
S
C
E
R
R
N
N
------
I
G
R
----
A
L
D
A
T
E
I
L
G
F
L
H
S
C
L
N
P
I
I
Y
-------
A
F
I
G
Q
N
F
R
H
G
F
L
K
I
L
A
M
H
G
----------------------------
18
PsiBlast_PDB
52.70
34%
-31
- C4 -
3C5T
2
GLP1R_HUMAN
A:
[13-85]
---------------------------------------------------
V
Q
K
W
R
E
Y
R
R
Q
C
Q
---
R
S
L
---
T
E
------
D
---
P
PP
A
------
T
D
L
F
C
N
R
T
F
D
E
--------
Y
A
C
W
P
D
G
E
P
G
S
F
V
N
V
S
C
P
W
Y
L
P
W
A
S
S
V
P
--
Q
--
G
H
V
Y
R
F
C
T
A
E
G
L
W
L
Q
K
D
N
S
S
L
P
W
R
D
---
L
S
E
C
E
E
S
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.58
41%
-48
- C4 -
3L2J
-
MALE_ECOLI (first)
A:
[450-494]
--------------------------------------------------------------------------------------------------
C
L
P
E
W
D
H
--------
I
L
C
W
P
L
G
A
P
G
E
V
V
A
V
P
C
P
D
Y
I
Y
D
F
N
H
-
K
--
G
--
H
A
Y
R
R
-
C
D
R
N
G
S
W
E
L
V
P
G
H
N
R
T
W
A
N
---
Y
S
E
C
V
K
F
L
T
N
E
T
R
E
R
--
E
V
-
F
D
R
L
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.25
41%
-33
- C4 -
3C4M
1
MALE_ECOLI (first)
A:
[454-498]
--------------------------------------------------------------------------------------------------
C
L
P
E
W
D
H
--------
I
L
C
W
P
L
G
A
P
G
E
V
V
A
V
P
C
P
D
Y
I
Y
D
F
N
H
-
K
--
G
--
H
A
Y
R
R
-
C
D
R
N
G
S
W
E
L
V
P
G
H
N
R
T
W
A
N
---
Y
S
E
C
V
K
F
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
52.06
34%
-32
- C4 -
3C59
1
GLP1R_HUMAN
A:
[13-85]
---------------------------------------------------
V
Q
K
W
R
E
Y
R
R
Q
C
Q
---
R
S
L
---
T
E
------
D
---
P
PP
A
------
T
D
L
F
C
N
R
T
F
D
E
--------
Y
A
C
W
P
D
G
E
P
G
S
F
V
N
V
S
C
P
W
Y
L
P
W
A
S
S
V
P
--
Q
--
G
H
V
Y
R
F
C
T
A
E
G
L
W
L
Q
K
D
N
S
S
L
P
W
R
D
---
L
S
E
C
E
E
S
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
51.99
32%
-38
- C4 -
3IOL
1
GLP1R_HUMAN
A:
[10-89]
--------------------------------------------TVS
L
W
E
T
V
Q
K
W
R
E
Y
R
R
Q
C
Q
---
R
S
L
---
T
E
------
D
---
P
PP
A
------
T
D
L
F
C
N
R
T
F
D
E
--------
Y
A
C
W
P
D
G
E
P
G
S
F
V
N
V
S
C
P
W
Y
L
P
W
A
S
S
V
P
--
Q
--
G
H
V
Y
R
F
C
T
A
E
G
L
W
L
Q
K
D
N
S
S
L
P
W
R
D
---
L
S
E
C
E
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------