@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
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Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : GP179_HUMAN: (2016-01-10 )
MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSGNWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPEVRGQVQMDVDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASPSGGLEESDFQTTGQFGFPEGRSGRLLQCLPCPEGCTSCMDATPCLVEEAAVLRAAVLACQACCMLAIFLSMLVSYRCRRNKRIWASGVVLLETVLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKLYRVLQLFLSRTAQRSALLSSGRLLRRLGLLLLPVLGFLAVWTVGALERGIQHAPLVIRGHTPSGRHFYLCHHDRWDYIMVVAELLLLCWGSFLCYATRAVLSAFHEPRYMGIALHNELLLSAAFHTARFVLVPSLHPDWTLLLFFFHTHSTVTTTLALIFIPKFWKLGAPPREEMVDEVCEDELDLQHSGSYLGSSIASAWSEHSLDPGDIRDELKKLYAQLEVHKTKEMAANNPHLPKKRGSSCQGLGRSFMRYLAEFPEALARQHSRDSGSPGHGSLPGSSRRRLLSSSLQEPEGTPALHKSRSTYDQRREQDPPLLDSLLRRKLAKKASRTESRESVEGPPALGFRSASAHNLTVGERLPRARPASLQKSLSVASSREKALLMASQAYLEETYRQAKEREERKKAKAAMASLVRRPSARRLERPRGAPLSAPPSPAKSSSVDSSHTSGRLHEEARRRLPHPPIRHQVSTPILALSGGLGEPRMLSPTSTLAPALLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAESQSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.-------......300.......310---.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430....-----.----.--.440.......450....-...-460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740----.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840--.......850.......860.......870.......880.......890.......900...----...---.910.......920.......930-----------.........940.......950...--....960.......970.......980.......990....--...1000...------------.----..1010......1020......1030......1040......1050......1060......1070...-...1080...-...1090......1100......1110........1120..-....1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......1970......1980......1990......2000......2010......2020......2030......2040......2050......2060......2070......2080......2090......2100......2110......2120......2130......2140......2150......2160......2170......2180......2190......2200......2210......2220......2230......2240......2250......2260......2270......2280......2290......2300......2310......2320......2330......2340......2350......2360....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGTRGAVMPP
P
M
W
G
L
L
G
C
C
F
V
C
A
W
ALGGPRPIRSLPPLSSQVKPGSV
P
M
QVPLEG
A
E
A
A
L
A
Y
L
YSG
D
A
Q
Q
L
S
QV
N
C
S
E
R
Y
EARGAGAMPGLPPSLQG
A
A
G
T
L
A
Q
A
A
N
F
L
N
M
L
L
QANDIR
E
S
S
V
E
E
D
V
E
W
Y
Q
A
L
V
R
S
V
AEG
D
P
R
V
Y
R
A
L
L
T
FNPPPG
A
S
H
L
Q
L
A
L
Q
ATRTG
E
E
T
I
L
Q
DLSGNWVQEENPPGDL
D
T
P
A
L
K
K
R
V
L
T
N
D
L
G
SLGSPKWPQADGYVGDT
Q
Q
V
RLSPP
F
L
E
CQEGRLRP
G
W
L
I
T
L
S
A
T
F
YGLKPDLSPEVR
G
Q
V
Q
M
D
V
D
L
Q
SV
D
I
N
QCASGPGWYSN
T
H
-------
L
CDLNST
Q
C
V
PLESQ
G
F
V
L
---
G
R
Y
L
C
RCRPGFYGASPSGGLEESDFQTTGQFGFPEGRSG
R
L
L
Q
C
LPCP
E
G
C
T
S
C
MDA
T
P
C
L
V
E
E
A
A
V
L
R
A
A
V
L
A
C
Q
A
C
C
M
L
A
I
F
L
S
M
L
V
S
Y
R
CRRN
K
R
IWA
S
G
V
V
L
L
E
T
V
L
F
G
F
L
L
L
Y
F
P
V
F
I
L
-----Y----F--K
P
S
V
F
R
C
I
A
L
R
W
V
R
L
L
G
F
-
A
I
V
-
Y
G
T
I
I
L
K
L
Y
R
V
L
Q
L
F
L
S
R
T
A
Q
R
S
A
L
L
S
S
G
R
L
L
R
R
L
G
L
L
L
L
P
V
L
G
F
L
A
V
W
T
V
G
A
L
E
RGIQHA
P
L
V
I
RGHTPSG
R
H
F
Y
L
C
HHDRW
D
Y
I
M
V
V
A
E
L
L
L
L
C
W
G
S
F
L
C
Y
A
T
R
A
V
L
S
A
FHEP
R
Y
M
G
I
A
L
H
N
E
L
L
L
S
A
A
F
H
T
A
R
F
V
L
VPSLHPD
W
T
L
L
L
F
F
FHTHS
T
V
T
T
T
L
A
L
I
F
I
P
K
F
W
KLGAP
P
R
E
E
M
V
D
E
V
C
E
D
E
LDLQHSG
S
Y
L
G
S
S
I
A
S
A
W
S
EHSL
D
P
G
D
I
R
D
E
L
K
K
L
Y
A
Q
L
E
V
H
K
T
K
E
MAANNPHLPKKRGS
S
C
Q
G
L
G
R
S
F
M
R
Y
L
A
E
F
P
E
A
L
A
R
QHSRDSGSPG----HGSLP
G
S
S
R
R
R
L
L
S
S
S
LQEPEGTP
A
L
HKSRS
T
Y
D
Q
R
REQDP
P
L
L
D
S
L
L
R
R
K
L
A
K
K
ASRTESRESVEGPPALGFRSASAHNL
T
V
G
ERLPRAR
P
A
S
L
Q
K
S
L
S
--
V
ASSR
E
K
A
L
L
M
A
S
Q
A
Y
L
E
E
T
Y
R
Q
A
K
E
R
E
E
R
K
K
A
K
A
A
M
A
S
L
V
RRP
S
A
R
RLERPRGAPLSAPPSP----AKS---SSVDSSHTSGR
L
H
E
E
A
R
RRLPH-------------PPIRHQVST
P
I
L
A
LSGGLGEPRMLS--P
T
S
T
L
A
P
A
L
L
P
ALAPTPAPALAPVPVSPQSP
N
L
L
T
Y
ICPWE--NAELPAKQEN------------V----PQEGPSGPERGHHSPA
P
A
R
A
R
L
W
R
A
L
S
V
A
V
E
KSRAGENEMD
A
E
D
A
HHQREANDVDEDRPKIFPKSHSLK-APVQQG
S
M
R
S
-
L
G
L
A
I
K
A
L
T
RSRSTY
R
E
K
E
SVEESP--EGQNSGTAGESMGA-PSRSPRLGRPKAVSKQAALIPSD
D
K
E
S
L
Q
N
Q
QN
A
H
T
S
R
M
L
Q
V
C
Q
REGSR
E
Q
E
D
R
G
R
R
M
T
Q
G
L
G
E
R
K
A
E
RAG
K
T
G
L
A
M
L
R
Q
V
SRDKNIKQSKETPV
G
W
Q
E
L
P
K
A
G
L
Q
S
LGSADH
R
V
A
EVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGD
S
Q
K
K
RGEARGKSEPID
V
V
P
M
M
RK
K
P
E
R
L
V
R
E
Q
EAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGK
P
A
Q
E
A
V
K
D
L
P
Q
E
K
Q
K
T
R
KATFWKEQKPGG
D
L
E
SLCPWESTDFRGP
S
A
V
S
I
QAPGSSECSGS
L
G
S
G
I
A
E
V
C
LWEAGDAPAIQKAEICPWELDD
N
V
M
G
Q
E
M
L
S
LGT
G
R
E
S
L
Q
E
K
E
K
A
SRKGSF
G
E
M
G
E
Q
T
V
K
A
V
Q
K
L
S
Q
Q
Q
E
SVCPRESTVPGHSSPCLDNSSSKAG
S
Q
F
L
CNGGSRATQVC
P
Q
EDLRPEAQEATPAKTEICPWEV
N
E
R
T
R
E
E
WTSAQVPRGGESQ
K
D
K
E
KMPGKSEIEDVTAWEKPEG
Q
I
Q
KQEAVGPWESVDPGSFSPQPRPQDTER
P
Q
T
L
L
Q
MSGSVGSKAADICPLD
V
E
ENLTAGKAEICPWEVGAGAGEERAL
G
A
E
A
I
RKSPNDTGKVSADLGPRERAVTAPEKPQKPTPE
W
E
V
ACPWGSVGPGACSQHPGTLDADGP
K
A
G
F
Q
E
L
D
HMGCRPGEVCPW
E
A
Q
E
AATSEKAKIC
P
W
EVSEGTTGKGLDQKAGS
E
S
A
E
Q
R
E
K
A
L
E
KGRL
T
S
L
G
E
D
V
S
K
G
M
A
K
L
C
QQQE
T
I
C
I
WENKDLRESPAQAPKISDL
P
S
S
M
S
S
E
V
AEGHSLEATEKGDLRQDPKTGS
F
P
E
H
I
T
QEKAPAADTEEFTTEDGE
K
T
S
H
E
L
Q
SVCPWETTAP
A
D
S
V
S
H
L
D
RQRPDQPKAS
S
Q
R
L
V
STGGRAADVCPWDVPDAGVYKSDSSAKAETCP
W
E
V
TERIPVKGVSRQDGKGD
S
Q
E
E
KGRAPEKSEPKGVPVQKKP
E
M
A
D
F
R
Q
Q
EAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAG
S
V
E
T
R
V
A
E
V
C
L
W
E
V
VEAPSAKKAEICPWEAGGGAAEE
G
E
Q
E
R
E
SQGQG
E
M
F
L
QKAGPGG
T
E
E
H
F
S
K
A
AAKPR
E
Q
EAVCPGEGTGSGGLLPQSGALDPE
L
K
VS
P
K
EAG
S
M
G
S
R
M
A
E
L
C
Q
W
E
ITDPEG
N
K
IK
G
T
MADICPGEETGVPSEES
G
L
L
A
L
TAT
R
R
EFFPTAPEK
P
L
C
L
L
V
HG
P
L
D
HFFPESKIPCPKVSRPAST
F
T
L
E
G
V
R
E
LQGPSGLEPRTSLAPEP
S
L
Q
E
A
E
SQSSSLTEDSG
Q
V
A
F
E
A
Q
Y
EEFTPPTVYPWDWE
42
Fugue
68.89
16%
67
* C8 *
4MT0
1
?
A:
[1-445]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
T
M
I
P
Q
Y
E
Q
P
K
V
E
V
A
E
T
F
Q
N
D
T
S
V
S
S
I
R
A
V
DLG
W
H
D
Y
F
A
D
P
R
L
Q
K
L
I
D
I
A
L
E
R
N
T
S
L
R
T
A
V
L
N
S
E
I
Y
R
K
Q
Y
M
I
E
R
N
N
L
L
P
T
L
A
A
N
A
N
G
S
R
Q
G
S
L
S
G
G
N
V
S
S
S
Y
N
V
G
L
G
A
A
S
Y
E
L
D
L
F
G
-
R
V
R
S
S
S
E
A
A
L
Q
G
Y
F
A
--
S
V
A
N
R
D
A
A
H
L
S
L
I
A
T
V
A
K
A
Y
F
N
E
R
Y
A
E
E
A
M
S
L
A
Q
R
V
L
K
T
R
E
E
T
Y
N
A
V
R
I
A
V
Q
G
R
R
D
F
R
R
R
P
A
P
----
A
E
A
L
I
E
S
A
K
A
D
Y
A
H
A
A
R
S
R
E
Q
A
R
N
A
L
A
T
L
I
NRPIPEDLPAG
L
P
L
D
K
Q
F
F
V
E
--
K
L
P
A
G
L
S
S
E
V
L
L
D
R
P
D
I
R
A
A
E
H
A
L
K
Q
A
N
A
N
I
G
A
A
R
A
A
F
F
P
S
I
R
L
T
G
S
V
G
T
G
S
V
E
L
G
GL
F
K
S
G
T
G
V
W
A
F
------------
A
----
P
S
I
T
L
P
I
F
T
W
G
T
N
K
A
N
L
D
V
A
K
L
R
Q
Q
A
Q
I
V
A
Y
E
S
A
V
Q
S
A
F
Q
D
V
A
N
A
L
A
A
R
E
Q
L
D
K
A
Y
D
A
L
S
K
Q
S
R
A
S
K
E
A
-
L
R
L
V
G
L
R
Y
K
H
G
V
S
G
A
L
D
L
L
D
A
E
R
S
S
Y
S
A
E
G
A
A
L
S
A
Q
L
T
R
A
E
N
L
A
D
L
Y
K
A
L
G
G
G
L
K
R
D
T
Q
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
53.10
15%
1944
- C- -
3J8E
-
RYR1_RABIT
G:
[5003-5015]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
T
G
Q
E
S
Y
V
W
K
M
Y
Q
E
R
C
W
D
F
F
P
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
51.09
16%
360
- C6 -
2KW6
-
CDKA1_HUMAN
A:
[51-115]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
H
H
H
H
H
H
S
H
--
S
K
Y
A
E
L
L
A
I
I
E
E
L
G
K
E
I
R
P
T
Y
A
G
S
K
S
A
M
E
R
L
K
R
G
I
I
H
A
R
G
L
V
R
E
C
L
A
E
T
E
R
N
A
R
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.37
27%
-26
- C6 -
5CGC
4
?
A:
[12-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
A
P
I
A
A
V
V
F
A
C
L
G
--
L
L
A
T
L
F
V
T
V
V
F
I
I
Y
R
D
T
P
V
V
K
S
S
S
R
E
L
C
Y
I
I
L
A
G
I
C
L
G
Y
L
C
T
F
C
L
-----
I
----
A
--
K
P
K
Q
I
Y
C
Y
L
Q
R
I
G
I
G
L
S
P
-
A
M
S
-
Y
S
A
L
V
T
K
T
Y
R
A
A
R
I
L
A
M
S
K
K
N
I
F
E
M
L
R
I
D
E
G
L
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
N
A
A
K
S
E
L
D
K
A
I
G
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
T
G
T
W
D
A
Y
K
I
S
A
C
A
Q
L
V
I
A
F
I
L
I
C
I
Q
L
G
I
I
V
A
L
F
I
M
E
P
P
D
I
M
V
Y
L
I
C
N
T
T
N
L
G
V
V
A
P
L
G
Y
N
G
L
L
I
L
A
C
T
F
Y
A
F
K
T
R
N
V
P
A
N
F
N
E
A
K
Y
I
A
F
T
M
Y
T
T
C
I
I
W
L
A
F
V
P
I
Y
F
G
S
N
Y
----
K
I
I
T
M
C
F
S
V
S
L
S
A
T
V
A
L
G
C
M
F
V
P
K
V
Y
I
I
L
A
K
P
E
R
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
47.03
27%
-30
- C6 -
5CGD
4
?
A:
[12-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
A
P
I
A
A
V
V
F
A
C
L
G
--
L
L
A
T
L
F
V
T
V
V
F
I
I
Y
R
D
T
P
V
V
K
S
S
S
R
E
L
C
Y
I
I
L
A
G
I
C
L
G
Y
L
C
T
F
C
L
-----
I
----
A
--
K
P
K
Q
I
Y
C
Y
L
Q
R
I
G
I
G
L
S
P
-
A
M
S
-
Y
S
A
L
V
T
K
T
Y
R
A
A
R
I
L
A
M
S
K
K
N
I
F
E
M
L
R
I
D
E
G
L
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
N
A
A
K
S
E
L
D
K
A
I
G
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
T
G
T
W
D
A
Y
K
I
S
A
C
A
Q
L
V
I
A
F
I
L
I
C
I
Q
L
G
I
I
V
A
L
F
I
M
E
P
P
D
I
M
V
Y
L
I
C
N
T
T
N
L
G
V
V
A
P
L
G
Y
N
G
L
L
I
L
A
C
T
F
Y
A
F
K
T
R
N
V
P
A
N
F
N
E
A
K
Y
I
A
F
T
M
Y
T
T
C
I
I
W
L
A
F
V
P
I
Y
F
G
S
N
Y
----
K
I
I
T
M
C
F
S
V
S
L
S
A
T
V
A
L
G
C
M
F
V
P
K
V
Y
I
I
L
A
K
P
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.34
30%
336
- C10 -
4DFH
-
PVRL2_HUMAN
A:
[23-93]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
H
L
L
P
P
V
P
G
L
Y
I
S
L
V
T
W
Q
--
R
P
D
A
P
A
N
H
Q
N
------------
V
A
A
F
H
P
K
M
G
P
S
F
P
-----
S
P
K
P
G
S
E
R
L
---
S
F
V
S
A
K
Q
S
T
G
Q
D
T
E
A
E
L
Q
D
A
T
L
A
L
H
G
L
T
V
E
D
E
G
N
Y
T
C
E
F
A
T
F
P
K
-
G
S
V
R
G
M
T
W
L
R
-
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
45.30
30%
343
* C10 *
3R0N
1
PVRL2_HUMAN
A:
[23-93]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
H
L
L
P
P
V
P
G
L
Y
I
S
L
V
T
W
Q
--
R
P
D
A
P
A
N
H
Q
N
------------
V
A
A
F
H
P
K
M
G
P
S
F
P
-----
S
P
K
P
G
S
E
R
L
---
S
F
V
S
A
K
Q
S
T
G
Q
D
T
E
A
E
L
Q
D
A
T
L
A
L
H
G
L
T
V
E
D
E
G
N
Y
T
C
E
F
A
T
F
P
K
-
G
S
V
R
G
M
T
W
L
R
-
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.62
30%
357
- C10 -
4HZA
-
PVRL2_HUMAN
A:
[53-123]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
H
L
L
P
P
V
P
G
L
Y
I
S
L
V
T
W
Q
--
R
P
D
A
P
A
N
H
Q
N
------------
V
A
A
F
H
P
K
M
G
P
S
F
P
-----
S
P
K
P
G
S
E
R
L
---
S
F
V
S
A
K
Q
S
T
----
E
A
E
L
Q
D
A
T
L
A
L
H
G
L
T
V
E
D
E
G
N
Y
T
C
E
F
A
T
F
P
K
-
G
S
V
R
G
M
T
W
L
R
-
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
43.50
12%
67
- C5 -
3J9T
-
VA0D_YEAST
Q:
[1-345]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
G
V
Y
F
N
I
D
N
G
F
I
E
G
V
V
R
G
Y
R
N
G
L
L
S
N
N
Q
Y
I
N
L
T
Q
C
D
T
L
E
D
L
K
L
Q
L
S
-
S
T
D
Y
G
N
F
L
S
S
V
S
S
E
S
L
--
T
T
S
--
L
I
Q
E
Y
A
S
S
K
L
Y
H
E
F
N
Y
I
R
D
Q
S
S
G
S
T
R
K
F
M
D
Y
I
T
Y
G
Y
M
I
D
N
V
A
L
M
I
T
G
T
I
H
D
R
D
K
G
E
I
L
Q
R
C
H
P
LGWF
D
T
L
---
P
T
L
S
V
A
T
D
L
E
S
L
Y
E
T
V
L
V
D
T
P
L
-------------
A
P
----
Y
F
K
N
C
F
D
T
A
E
E
L
D
D
M
N
I
E
I
--
I
R
N
K
L
Y
K
A
Y
L
E
D
F
Y
N
F
V
T
E
E
I
P
E
-
P
A
K
E
C
M
Q
T
L
L
G
F
E
A
D
R
R
--
S
I
N
I
A
L
N
S
L
Q
SSDIDPDLKSDL
L
----
P
N
I
G
K
L
Y
P
L
A
T
F
H
L
A
Q
A
Q
D
F
E
G
V
R
A
A
L
A
N
V
Y
E
Y
R
G
F
L
E
T
G
N
L
E
D
H
F
Y
Q
L
E
M
E
L
C
R
D
A
F
T
Q
Q
F
A
I
S
T
V
W
A
W
M
K
S
K
E
Q
E
V
R
N
-
I
T
W
I
A
E
C
I
A
Q
-
N
Q
R
E
R
I
N
N
Y
I
S
V
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
42.91
38%
8593
- C2 -
3J8B
-
EIF3F_HUMAN
F:
[166-280]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
L
I
L
G
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.44
29%
343
- C10 -
4DFI
-
PVRL2_HUMAN
A:
[23-93]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
H
L
L
P
P
V
P
G
L
Y
I
S
L
V
T
W
Q
--
R
P
D
A
P
A
N
H
Q
N
------------
V
A
A
F
H
P
K
S
G
P
S
-----
F
S
S
P
K
P
G
S
E
R
L
---
S
F
V
S
A
K
Q
S
T
----
E
A
E
L
Q
D
A
T
L
A
L
H
G
L
T
V
E
D
E
G
N
Y
T
C
E
F
S
T
S
P
K
-
G
S
V
R
G
M
T
W
L
R
-
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
41.44
25%
786
- C6 -
1JEK
2
A:
[1-40]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
A
--
N
A
T
A
A
Q
Q
E
V
L
E
A
S
Y
A
M
V
Q
H
I
A
K
G
I
R
I
L
E
A
R
V
A
R
V
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
40.82
28%
782
- C6 -
2YY0
-
MYCBP_HUMAN
A:
[57-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
N
P
E
I
E
L
L
R
L
E
L
A
E
M
K
E
K
Y
E
A
I
V
E
E
N
K
K
L
K
A
K
L
A
Q
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
40.69
23%
1035
* C6 *
1BB1
1
?
A:
[4-34]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
A
A
I
E
Y
E
Q
A
A
I
K
E
E
I
A
A
I
K
D
K
I
A
A
I
K
E
Y
I
A
A
I
N
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
39.91
13%
-4
- C6 -
3ODU
4
CXCR4_HUMAN (first)
A:
[53-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
Y
S
I
I
F
L
T
G
I
V
G
N
G
L
V
I
L
V
M
G
Y
Q
K
K
L
R
--
S
M
T
D
K
Y
R
L
H
L
S
V
A
D
L
L
F
V
I
T
L
P
F
W
A
V
D
A
V
A
N
----
W
--
Y
F
G
N
F
L
C
K
A
V
H
V
I
Y
T
V
N
L
-
Y
S
S
V
W
I
L
A
F
I
S
L
D
R
Y
L
A
I
V
H
A
T
N
S
Q
R
P
R
K
L
L
A
E
K
V
V
Y
V
G
V
W
I
P
A
L
L
L
T
I
P
D
F
I
F
A
N
V
S
E
A
D
D
R
Y
I
C
D
R
F
Y
P
N
D
L
W
V
V
V
F
Q
F
Q
H
I
M
V
G
L
I
L
P
G
I
V
I
L
S
C
Y
C
I
I
I
S
K
L
S
H
S
G
S
N
I
F
E
M
L
R
I
D
E
G
L
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
N
A
A
K
S
E
L
D
K
A
I
G
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
T
G
T
W
D
A
Y
G
S
K
G
H
Q
K
R
K
A
L
K
T
T
V
I
----
L
I
L
A
F
F
A
C
W
L
P
Y
Y
I
G
I
S
I
D
S
F
I
L
L
E
I
I
K
Q
G
C
E
F
E
N
T
V
H
K
W
I
S
I
T
E
A
L
A
F
F
H
C
C
L
N
P
I
L
Y
A
F
L
G
A
K
F
K
T
S
A
Q
H
A
L
T
S
G
R
P
L
E
V
L
F
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.83
38%
597
- C7 -
1G1R
2
LYAM3_HUMAN
A:
[99-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
P
G
K
W
N
D
E
H
CLK
K
K
H
A
L
C
Y
T
A
S
C
Q
D
M
S
C
S
K
Q
G
E
C
L
E
T
I
G
N
Y
T
C
S
C
Y
P
G
F
Y
G
P
E
C
E
Y
V
R
D
D
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
39.47
10%
-7
- C6 -
3V2Y
1
ENLYS_BPT4
A:
[68-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
F
I
L
I
C
C
F
I
I
L
E
N
I
F
V
L
L
T
I
W
K
T
K
K
F
H
--
R
P
M
Y
Y
F
I
G
N
L
A
L
S
D
L
L
A
G
V
A
Y
T
A
N
L
-----
L
L
SGA
T
TY
K
L
T
P
A
Q
W
F
L
R
E
G
S
M
F
V
A
L
S
A
S
V
-
F
S
L
L
A
I
A
I
E
R
Y
I
T
M
L
K
N
N
F
R
L
F
L
L
I
S
A
C
W
V
I
S
L
I
L
G
G
L
P
I
M
G
W
N
C
I
S
A
L
S
S
C
S
T
V
L
P
L
Y
H
K
H
Y
I
L
F
C
T
T
V
F
T
L
L
L
L
S
I
V
I
L
Y
C
R
I
Y
S
L
V
R
T
R
N
I
F
E
M
L
R
I
D
E
G
L
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
N
A
A
K
S
E
L
D
K
A
I
G
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
T
G
T
W
D
A
Y
A
S
R
S
S
E
N
V
A
L
L
K
T
V
I
I
V
L
S
V
F
I
A
C
W
A
P
L
F
I
L
----
L
L
L
D
V
G
C
K
V
K
T
C
D
I
L
F
R
A
E
Y
F
L
V
L
A
V
L
N
S
G
T
N
P
I
I
Y
T
L
T
N
K
E
M
R
R
A
F
I
R
I
M
G
R
P
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
39.44
6%
178
- C8 -
4JLE
5
?
A:
[19-167]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
A
E
E
I
N
E
M
I
N
S
S
N
E
F
I
N
R
N
D
M
N
I
I
F
S
Y
V
H
E
S
E
R
E
K
F
K
K
V
E
E
N
I
F
K
F
I
Q
S
I
V
E
T
Y
K
I
P
D
E
Y
K
M
R
K
F
K
F
A
H
F
E
M
Q
G
Y
A
L
K
Q
E
K
F
L
L
E
Y
A
F
L
S
L
N
GK
L
C
E
R
K
K
F
K
E
V
L
E
Y
V
K
R
E
W
I
E
F
R
K
S
M
F
D
V
W
K
E
K
L
A
S
E
F
R
E
H
G
E
M
L
N
Q
K
R
K
L
K
Q
H
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_CBE
39.23
38%
620
- C7 -
1G1Q
1
LYAM3_HUMAN
B:
[99-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
P
G
K
W
N
D
E
H
CLKKKHA
L
C
Y
T
A
S
C
Q
D
M
S
C
S
K
Q
G
E
C
L
ETI
G
N
Y
T
C
S
C
Y
P
G
F
Y
G
P
E
C
E
Y
V
R
D
D
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
39.03
38%
630
- C7 -
1G1R
1
LYAM3_HUMAN
D:
[99-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
P
G
K
W
N
D
E
H
CLKKKHA
L
C
Y
T
A
S
C
Q
D
M
S
C
S
K
Q
G
E
C
L
ETI
G
N
Y
T
C
S
C
Y
P
G
F
Y
G
P
E
C
E
Y
V
R
D
D
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------