@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : O13C6_HUMAN: (2016-01-11 )
MVSANQTASVTEFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRKTISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPIRLPAPG
Atome Classification :
(20 SA)
----------.........10........20........30.------....-----...-40.---.-------......50........-----60........70.......-.80........90........100...-...-------------.110.......120-.......--------------.130.......140.......150----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MVSANQT
A
S
V
T
E
F
I
L
LGLSAHP
K
L
E
K
T
F
F
V
L
I
------
L
L
M
Y
-----
L
V
I
-
L
LG---N-------
G
V
L
I
L
M
TVSNSHLH
M
P
-----
M
Y
F
F
LGN
L
S
F
L
D
I
C
YTTSS-
V
P
L
I
L
D
S
FLTPRKTI
S
F
S
A
C
A
V
Q
M
F
L
S
-
F
AM-------------G
A
T
E
C
V
L
L
S
M
M
A
F
--
D
R
Y
V
A
I
C--------------NPLRY
P
V
V
MSKA
A
Y
M
P
I
RLPAPG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
82.61
22%
-127
- C6 -
1F88
8
OPSD_BOVIN
A:
[1-348]
MN
G
T
E
G
PNFY
V
P
F
S
N
K
T
G
V
V
R
S
-
P
F
E
A
P
Q
Y
Y
L
A
E
P
W
Q
F
S
M
L
A
------
A
Y
M
F
-----
L
L
I
-
M
L
G
F
P
I
N
-------
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
-----
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
-
T
L
G
-------------
G
E
I
A
L
W
S
L
V
V
L
A
I
--
E
R
Y
V
V
V
C
--------------
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
AAPPLVGW
S
R
Y
I
P
E
GMQC
S
C
G
I
DYYTPHEETN
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VFTVKEAAASATTQK
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QGSDFGPIFM
T
I
P
A
F
F
A
K
TSAVY
N
P
V
I
Y
I
M
MN
K
Q
F
R
N
C
M
V
T
T
L
C
CGKNPSTTVSKTETS
Q
V
A
P
A----------
27
HHSearch
81.74
24%
-154
- C6 -
2Z73
5
OPSD_TODPA
A:
[32-152]
--------------------------------
A
V
Y
Y
S
L
G
I
F
I
------
G
I
C
G
-----
I
I
G
-
C
G
G
---
N
-------
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
-----
A
N
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
-
G
I
F
-------------
G
F
M
S
I
M
T
M
A
M
I
S
I
--
D
R
Y
N
V
I
G
--------------
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
76.47
23%
-140
- C6 -
3SN6
1
R:
[187-296]
---------------------------------------
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
H
I
L
T
K
T
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
76.31
21%
-150
- C1 -
1AER
1
TOXA_PSEAE
A:
[1-211]
---AFLGDG
G
D
V
S
F
S
T
R
G
T
Q
N
W
T
V
E
R
L
L
Q
A
H
R
Q
L
E
E
R
G
Y
V
F
V
G
Y
H
G
T
F
L
E
A
A
-----
Q
S
I
-
V
F
G
---
G
VRAAIW
R
G
F
Y
I
A
G
D
P
A
L
A
Y
G
Y
A
Q
DQEPD
A
R
G
R
I
R
N
G
A
L
L
R
V
Y
V
P
R
S
S
-
L
P
G
F
Y
R
T
S
L
T
L
A
A
--
P
E
A
A
G
E
V
E
R
L
I
G
-
H
P
L
PLRL
D
A
I
T
G
P
EEE
G
G
R
L
E
T
I
L
G
W
P
L
A
--
E
R
T
V
V
I
P
S
A
I
P
T
D
PRNVGGDL
D
P
S
S
I
P
D
K
E
Q
A
I
S
A
L
P
D
Y
A
S
Q
P
G
KPPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
75.72
21%
-140
- C6 -
2RH1
5
ADRB2_HUMAN (first)
A:
[40-157]
----------------------------------
V
V
G
M
G
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
H
I
L
M
K
M
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.34
23%
-135
- C6 -
4LDL
3
ADRB2_HUMAN
A:
[187-296]
---------------------------------------
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
H
I
L
T
K
T
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
75.29
23%
-134
- C6 -
4LDO
3
A:
[187-296]
---------------------------------------
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
H
I
L
T
K
T
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
75.16
22%
-108
- C6 -
1U19
15
OPSD_BOVIN
A:
[4-349]
MN
G
T
E
G
PNFY
V
P
F
S
N
K
T
G
V
V
R
S
P
F
E
A
P
Q
Y
-
Y
L
A
E
P
W
Q
F
S
M
L
A
------
A
Y
M
F
-----
L
L
I
-
M
L
G
F
P
I
N
-------
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
-----
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
-
T
L
G
-------------
G
E
I
A
L
W
S
L
V
V
L
A
I
--
E
R
Y
V
V
V
C
--------------
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
GW
S
R
Y
I
P
E
GMQC
S
C
G
I
DYYTPHEETN
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VFTVKEAAAQQQESA
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QGSDFGPIFM
T
I
P
A
F
F
A
KTSAV
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
CGKNPLGDDEA
S
T
T
V
S
K
TETSQVAPA
2
PsiBlast_PDB
75.04
26%
-141
- C6 -
4MQT
2
ACM2_HUMAN
A:
[36-150]
-----------------------------------
K
T
F
E
V
V
F
------
I
V
L
V
A
G
S
L
S
L
V
T
-
I
I
G
---
N
-------
I
L
V
M
V
S
I
K
V
N
R
H
L
Q
T
V
-----
N
N
Y
F
L
F
S
L
A
C
A
D
L
I
I
G
V
F
S
-
M
N
L
Y
T
L
Y
T
V
I
G
Y
W
P
L
G
P
V
V
C
D
L
W
L
A
L
D
-
Y
V
V
-------------
S
N
A
S
V
M
N
L
L
I
I
S
F
--
D
R
Y
F
C
V
T
--------------
K
P
L
T
Y
P
V
K
R
T
T
K
M
A
G
M
M
I
A
A
A
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
74.62
21%
-146
- C6 -
3UON
2
ACM2_HUMAN (first)
A:
[25-141]
------------------------------------
F
I
V
L
V
A
------
G
S
L
S
-----
L
V
T
-
I
I
G
---
N
-------
I
L
V
M
V
S
I
K
V
N
R
H
L
Q
T
V
-----
N
N
Y
F
L
F
S
L
A
C
A
D
L
I
I
G
V
F
S
-
M
N
L
Y
T
L
Y
T
V
I
G
Y
W
P
L
G
P
V
V
C
D
L
W
L
A
L
D
-
Y
V
V
-------------
S
N
A
S
V
M
N
L
L
I
I
S
F
--
D
R
Y
F
C
V
T
--------------
K
P
L
T
Y
P
V
K
R
T
T
K
M
A
G
M
M
I
A
A
A
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
74.45
27%
-159
- C6 -
4ZWJ
-
?
A:
[197-303]
-------------------------------------
F
S
M
L
A
------
A
Y
M
F
-----
L
L
I
-
V
L
G
F
P
I
N
-------
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
-----
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
L
G
G
-
F
T
S
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
Q
G
F
F
A
-
T
L
G
-------------
G
E
I
A
L
W
S
L
V
V
L
A
I
--
E
R
Y
V
V
V
C
--------------
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.34
23%
-130
- C6 -
4LDE
3
A:
[187-296]
---------------------------------------
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
H
I
L
T
K
T
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
73.99
27%
-135
- C6 -
3QAK
2
ENLYS_BPT4
A:
[18-127]
--------------------------------
I
M
G
S
S
V
Y
I
T
V
------
E
L
A
I
-----
A
V
L
A
I
L
G
---
N
-------
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
-----
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
-----
F
A
I
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
-------------
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
--------------
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
73.99
26%
-137
- C6 -
4MQS
1
?
A:
[36-150]
-----------------------------------
K
T
F
E
V
V
F
------
I
V
L
V
A
G
S
L
S
L
V
T
-
I
I
G
---
N
-------
I
L
V
M
V
S
I
K
V
N
R
H
L
Q
T
V
-----
N
N
Y
F
L
F
S
L
A
C
A
D
L
I
I
G
V
F
S
-
M
N
L
Y
T
L
Y
T
V
I
G
Y
W
P
L
G
P
V
V
C
D
L
W
L
A
L
D
-
Y
V
V
-------------
S
N
A
S
V
M
N
L
L
I
I
S
F
--
D
R
Y
F
C
V
T
--------------
K
P
L
T
Y
P
V
K
R
T
T
K
M
A
G
M
M
I
A
A
A
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
73.64
27%
-138
- C6 -
3EML
8
ENLYS_BPT4
A:
[18-127]
--------------------------------
I
M
G
S
S
V
Y
I
T
V
------
E
L
A
I
-----
A
V
L
A
I
L
G
---
N
-------
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
-----
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
-----
F
A
I
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
-------------
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
--------------
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
72.52
23%
-134
- C6 -
4QKX
2
ADRB2_HUMAN
A:
[187-296]
---------------------------------------
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
A
A
C
I
L
T
K
T
W
T
F
G
N
F
W
C
E
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
71.23
21%
-146
- C6 -
3EML
8
ENLYS_BPT4
A:
[21-136]
----------------------------------
S
S
V
Y
I
T
V
E
------
L
A
I
A
-----
V
L
A
-
I
L
G
---
N
-------
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
-----
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
T
I
S
T
--
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
-
L
V
L
-------------
T
Q
S
S
I
F
S
L
L
A
I
A
I
--
D
R
Y
I
A
I
R
--------------
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
70.54
27%
-138
- C6 -
2X72
3
GNAT1_BOVIN (first)
A:
[40-144]
-------------------------------------
F
S
M
L
A
------
A
Y
M
F
-----
L
L
I
-
M
L
G
F
P
I
N
-------
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
-----
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
Q
G
F
F
A
-
T
L
G
-------------
G
E
I
A
L
W
S
L
V
V
L
A
I
--
E
R
Y
V
V
V
C
--------------
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
70.43
21%
-145
- C6 -
2R4R
-
ADRB2_HUMAN
A:
[37-151]
--------------------------------------
G
I
V
M
------
S
L
I
V
-----
L
A
I
-
V
F
G
---
N
-------
V
L
V
I
T
A
I
A
-
F
E
R
L
Q
T
V
-----
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
F
G
-----------------
F
W
T
S
I
D
-
V
L
C
-------------
V
T
A
S
I
E
T
L
C
V
I
A
V
--
D
R
Y
F
A
I
T
--------------
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
68.43
18%
-150
- C6 -
2KS9
1
NK1R_HUMAN
A:
[34-146]
------------------------------------
L
W
A
A
A
Y
------
T
V
I
V
-----
V
T
S
-
V
V
G
---
N
-------
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
-----
T
N
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
N
F
F
P
-
I
A
A
-------------
V
F
A
S
I
Y
S
M
T
A
V
A
F
--
D
R
Y
M
A
I
I
--------------
H
P
L
Q
P
R
L
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------