@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2B8_HUMAN: (2016-01-13 )
MDQKNGSSFTGFILLGFSDRPQLELVLFVVLLIFYIFTLLGNKTIIVLSHLDPHLHTPMYFFFSNLSFLDLCYTTGIVPQLLVNLRGADKSISYGGCVVQLYISLGLGSTECVLLGVMVFDRYAAVCRPLHYTVVMHPCLYVLMASTSWVIGFANSLLQTVLILLLTLCGRNKLEHFLCEVPPLLKLACVDTTMNESELFFVSVIILLVPVALIIFSYSQIVRAVMRIKLATGQRKVFGTCGSHLTVVSLFYGTAIYAYLQPGNNYSQDQGKFISLFYTIITPMINPLIYTLRNKDVKGALKKVLWKNYDSR
Atome Classification :
(20 SA)
--------------.........10-----.......----..---------------20....-------....30........40........50........60----........70......-..--80........90.....-...100..------..----...110...---.---------------...120.......130.......140.......150.......160......-.170.----......180.......190-----.........200.....---..210.......220-------.........230----------.--------------------.--------.----.....240.......250-------------.........260..--.---.-..---...270-------.......280-........290.....---..-------300.......310---------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------MDQKNGS
S
F
T
------
G
F
I
L
LGF----SD---------------RP
Q
L
E
L
-------
V
L
F
V
V
L
L
I
F
Y
I
F
T
L
LGN
K
T
I
I
V
L
SHLDPHLH
T
P
M
Y
F
----
F
FSN
L
S
F
L
D
L
C
Y
TTG
I
-
V
P
--
Q
L
L
V
N
LRGADKSISYG
G
-
C
V
V
Q
L
Y
I
S------LG----LGS
T
E
C
V
L
L
---
G
---------------
V
M
V
F
D
R
Y
A
A
V
CRP
L
H
Y
T
V
V
M
H
P
C
L
Y
V
L
MAST
S
W
V
I
G
F
A
N
S
L
L
Q
T
V
L
I
L
L
L
T
L
-CG
R
N
K
----
L
E
H
F
L
CEVPP
L
L
K
L
A
CV-------DTTMNES
E
L
F
F
V
S
V
I
I
L
---
L
V
P
V
A
L
I
I
F
S
Y
S
Q
---------
I
V
R
A
V
M
R
I
KLA-----------T--------------------G--------Q----R
K
V
F
GTCGS
H
L
T
V
V
S
L
---------------
F
YG
T
A
I
Y
A
Y
L--QP--G---N-NY---SQDQ
G
K
-------
F
I
S
L
F
Y
T
I
I
--
T
P
M
I
N
P
L
I
Y
T
LRNK
D
V
---
K
G
-------
A
L
K
K
V
L
W
KNYDSR---------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
85.18
19%
-111
- C5 -
1F88
8
OPSD_BOVIN
A:
[1-348]
--------------
M
N
G
T
E
G
P
N
F
Y
VPFSNK
T
G
V
V
R
S
P
----
F
E
---------------
A
P
Q
Y
Y
L
AE
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
----
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
--
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
-
C
N
L
E
G
F
F
A
------
T
L
----
G
G
E
I
A
L
W
S
L
---
V
---------------
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
V
F
T
V
K
E
A
A
A
S
-----------
A
--------------------
T
--------
T
----
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
---------------
A
F
L
I
C
W
L
P
Y
A
--
G
V
--
A
---
F
-
Y
I
---
F
T
H
Q
G
S
DFGPIFM
T
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
P
S
TTVSKTETS
Q
V
A
P
A-------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
84.44
16%
-125
- C5 -
2Z73
5
OPSD_TODPA
A:
[34-332]
--------------------------------------------------------------
Y
Y
-------
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
----
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
--
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
-
C
K
V
Y
G
F
I
G
------
G
I
----
F
G
F
M
S
I
M
T
M
---
A
---------------
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
----
T
L
-
E
----
G
V
L
C
N
C
S
F
D
Y
I
S
------------
R
D
S
T
T
R
S
N
I
L
C
M
F
I
L
G
F
---
F
G
P
I
L
I
I
F
F
C
Y
F
N
---------
I
V
M
S
V
S
N
H
E
K
E
-----------
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
--------
E
----
M
R
L
A
K
I
S
I
V
I
V
S
Q
F
L
L
---------------
S
W
S
P
Y
A
V
V
A
L
--
L
A
--
Q
FG-
P
L
E
W
---
V
T
P
Y
A
A
-------
Q
L
P
V
M
F
A
K
A
--
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
---
R
E
-------
A
I
S
Q
T
F
P
W
V
L
T
C
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
79.52
19%
-111
- C5 -
1U19
15
OPSD_BOVIN
A:
[4-349]
--------------
M
N
G
T
E
G
P
N
F
--------
Y
V
P
F
S
N
----
K
T
GVVRSPFEAPQYYLA
E
P
W
Q
F
S
-------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
----
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
--
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
-
C
N
L
E
G
F
F
A
------
T
L
----
G
G
E
I
A
L
W
S
L
---
V
---------------
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
--------
P
P
L
-
V
G
W
S
R
----
Y
------
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
V
F
T
V
K
E
A
A
A
Q
-----------
Q
--------------------
Q
--------
E
SA
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
---------------
A
F
L
I
C
W
L
P
Y
A
--
G
V
--
A
---
F
-
Y
I
---
F
T
H
Q
G
S
DFGPIFM
T
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
P
L
GDDEA
S
T
T
V
S
K
TETSQVAPA-------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
77.93
14%
-118
* C5 *
2KS9
1
NK1R_HUMAN
A:
[35-324]
------------------------------------------------------------------------
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
----
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
--
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
-
C
K
F
H
N
F
F
P
------
I
A
----
A
V
F
A
S
I
Y
S
M
---
T
---------------
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
-
T
T
----
E
T
-
M
----
P
S
R
V
V
C
M
I
E
W
P
E
H
P
----------
N
K
I
Y
E
K
V
Y
H
I
C
V
T
V
L
I
Y
---
F
L
P
L
L
V
I
G
Y
A
Y
T
V
---------
V
G
I
T
L
W
A
S
E
I
P
GDSSDRYH
E
Q
V
S
--------------------
A
--------
K
----
R
K
V
V
K
M
M
I
V
V
V
C
T
F
A
I
---------------
C
W
L
P
F
H
I
F
F
L
--
L
P
--
Y
I
NP
D
-
L
Y
LKK
F
I
Q
Q
V
Y
-------
L
A
I
M
W
L
A
M
S
--
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
---
R
L
-------
G
F
K
H
A
F
R
C
C
P
F
I
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
72.97
17%
-120
- C5 -
1U19
14
OPSD_BOVIN
A:
[41-326]
---------------------------------------------------------------
S
-------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
----
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
--
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
-
C
N
L
E
G
F
F
A
------
T
L
----
G
G
E
I
A
L
W
S
L
---
V
---------------
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
----
I
P
-
E
----
G
M
Q
C
S
C
G
I
D
Y
Y
T
P
---
H
-------
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
V
F
T
V
K
E
A
A
A
Q
-----------
Q
--------------------
Q
ESA
T
T
Q
K
A
E
----
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
---------------
C
W
L
P
Y
A
G
V
A
F
--
Y
I
F
T
H
---
Q
G
S
D
---
F
G
P
I
F
M
-------
T
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
P
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
72.74
14%
-98
- C5 -
2RH1
16
ADRB2_HUMAN (first)
A:
[36-477]
----------------------------------------------------------
D
E
V
W
V
V
-------
G
M
G
I
V
M
S
L
I
V
L
A
I
V
F
G
N
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
T
N
Y
----
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
-
V
P
--
F
G
A
A
H
I
L
M
K
M
W
T
F
G
N
F
W
-
C
E
F
W
T
S
I
D
------
V
L
----
C
V
T
A
S
I
E
T
L
---
C
---------------
V
I
A
V
D
R
Y
F
A
I
T
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
W
I
V
S
G
L
T
S
F
L
P
I
Q
M
--------
H
W
Y
R
----
A
T
H
Q
E
A
I
N
C
Y
A
E
E
T
C
C
--------
D
F
F
T
N
Q
A
Y
A
I
A
S
S
I
V
S
F
---
Y
V
P
L
V
I
M
V
F
V
Y
S
R
---------
V
F
Q
E
A
K
R
Q
L
N
I
-----------
F
--------------------
E
--------
M
----
L
R
I
D
E
--
G
L
R
L
K
I
Y
K
D
---------------
T
E
G
Y
Y
T
I
G
I
G
--
H
L
--
L
---
T
-
K
S
---
P
S
L
N
A
A
-------
K
S
E
L
D
K
A
I
G
--
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
---
N
Q
-------
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
LD
A
V
R
R
A
A
L
I
N
M
V
F
Q
MG
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
KR
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
TGTWDAYKFCL
K
E
H
K
A
L
K
T
L
G
I
I
M
G
T
F
T
L
C
W
L
P
F
F
I
V
N
I
V
H
V
I
QDNLIR
K
E
V
Y
I
L
L
N
W
I
G
Y
V
N
S
G
F
N
PLIYCRS
P
D
F
R
I
A
F
Q
E
L
L
CL
48
Fugue
72.30
14%
-129
- C4 -
4TQG
1
?
A:
[1-319]
--------------------
S
Q
I
N
------
D
K
T
I
M
I
F
----
G
G
---------------
S
G
S
L
G
N
-------
R
L
I
E
T
Y
I
---------
N
N
N
I
I
V
N
Y
S
R
D
E
S
K
H
W
S
M
E
L
----
K
Y
K
S
D
K
L
K
N
I
I
G
D
I
R
D
-
F
E
--
K
V
Q
Q
S
I
M
R
I
N
P
D
I
I
I
I
A
-
A
A
L
K
H
I
D
R
------
C
E
----
Y
E
I
N
E
C
L
D
T
---
N
---------------
I
K
G
L
Q
N
V
L
K
V
T
E
I
N
R
S
N
--
L
S
N
L
K
A
V
C
F
V
S
T
D
K
A
C
S
P
V
N
S
Y
G
M
S
K
A
I
C
E
T
L
V
-
V
E
K
S
K
Y
I
KD
I
K
Y
V
C
V
R
Y
G
N
V
L
N
F
T
L
T
-------
H
T
S
M
T
R
F
I
M
T
L
D
D
S
V
K
L
---
I
E
Y
A
I
I
N
G
N
S
G
E
I
---------
V
I
P
K
L
N
S
M
Y
I
K
-----------
D
--------------------
M
--------
I
----
E
L
F
A
D
K
--
Y
P
I
V
I
T
G
L
---------------
R
S
G
E
R
M
Y
E
S
L
IN
D
T
--
Q
---
S
-
M
K
---
T
V
P
K
G
D
------------
Y
Y
H
I
--
L
P
T
Y
D
P
T
I
V
T
E
E
F
Y
E
Y
S
SK
Q
N
-------
I
L
S
K
Q
E
L
E
N
Y
L
N
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.09
21%
-121
- C5 -
3DQB
6
GNAT1_BOVIN (first)
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
71.52
21%
-118
- C5 -
3PQR
9
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
71.20
21%
-107
- C5 -
3C9L
13
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
D
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
70.67
21%
-113
- C5 -
4J4Q
9
GNAT1_BOVIN (first)
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.48
21%
-115
- C5 -
4PXF
7
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
70.37
21%
-115
- C5 -
3PXO
5
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.20
21%
-113
- C5 -
2I35
3
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
D
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.19
21%
-111
- C5 -
1F88
7
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
----------------
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.15
21%
-121
- C5 -
3CAP
5
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.34
21%
-85
- C5 -
1GZM
15
OPSD_BOVIN
A:
[78-322]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
D
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
68.07
21%
-117
- C5 -
2I36
2
OPSD_BOVIN
A:
[75-321]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
--------
Q
----
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
ICWLP
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
67.65
15%
-136
- C3 -
1A6Q
3
PPM1A_HUMAN
A:
[2-368]
GAFLDKPKM
E
K
H
N
A
Q
G
Q
G
N
G
L
R
Y
G
------
L
S
S
M
Q
G
W
RVEM
E
D
---------------
A
H
T
A
V
I
G
LPSG--
L
E
S
W
S
F
F
A
V
Y
D
G
H
A
G
S
Q
V
A
K
Y
C
C
E
H
L
L
D
H
I
T
N
N
Q
D
F
KGSA
G
A
P
S
V
E
N
V
K
N
G
I
R
T
G
F
-
L
E
I
D
E
H
M
R
V
M
S
E
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
L
I
S
PQ
H
T
Y
F
I
N
----
C
G
D
S
R
G
L
L
C
R
NR
K
---------------
V
H
F
F
T
Q
D
H
K
P
S
N
P
L
E
K
E
R
I
Q
N
A
G
G
S
V
M
I
Q
R
V
N
G
S
L
A
V
S
R
A
L
G
D
F
D
Y
K
C
V
H
----
G
K
G
P
----
T
E
Q
L
---
V
S
P
E
P
E
V
H
D
I
-------
E
R
S
E
E
D
D
Q
F
I
I
L
A
C
D
G
I
W
D
V
M
G
N
E
E
L
C
D
F
V
R
S
R
L
E
V
TDD
L
E
K
V
C
N
E
V
V
D
T
C
L
Y
-----------
K
--------------------
G
--------
S
----
R
D
-------
N
M
S
V
I
L
I
---------------
C
F
P
N
A
P
K
V
S
P
--
E
A
--
V
---
K
-
K
E
---
A
E
L
D
K
Y
-------
L
E
C
R
V
E
E
I
I
KG
V
P
D
L
V
H
V
M
R
T
L
A
S
E
N
I
---
P
S
LPPGGEL
A
S
K
R
N
V
I
E
A
V
Y
N
R
L
N
PY-----------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
67.44
21%
-86
- C5 -
1HZX
14
OPSD_BOVIN
A:
[78-322]
-------------------------------------------------------------------------------------------------------------------------------------
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
------
L
H
GYFV
F
G
P
T
G
C
N
L
E
---
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
----
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
---
I
I
P
L
I
V
I
F
F
C
Y
G
Q
---------
L
---
V
F
T
V
K
E
A
-----------
A
--------------------
A
-----------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
--
H
Q
--
G
---
S
-
D
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
--
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
---
R
N
-------
C
M
V
T
T
L
C
C
G
K
N
P
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------