@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2T3_HUMAN: (2016-01-13 )
MCSGNQTSQNQTASTDFTLTGLFAESKHAALLYTVTFLLFLMALTGNALLILLIHSEPRLHTPMYFFISQLALMDLMYLCVTVPKMLVGQVTGDDTISPSGCGIQMFFYLTLAGAEVFLLAAMAYDRYAAVCRPLHYPLLMNQRVCQLLVSACWVLGMVDGLLLTPITMSFPFCQSRKILSFFCETPALLKLSCSDVSLYKTLMYLCCILMLLAPIMVISSSYTLILHLIHRMNSAAGHRKALATCSSHMIIVLLLFGASFYTYMLPSSYHTAEQDMMVSAFYTIFTPVLNPLIYSLRNKDVTRALRSMMQSRMNQEK
Atome Classification :
(20 SA)
--------.........10........20.----------.......30........40........50........60........70........80.-.......90........100.......110...-....120.......130...-....140.......150.......160.......170.......180.......190..-------.-------....200.......210.......220.....----..230---.----....-----------.--------------------..240----.........250.-------....--------..260.......270--..-------.-------..--...280.......290.......300.......310-........----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MCSGNQTSQNQTAST
D
F
T
L
T
G
L
----------FAESKH
A
A
L
L
Y
T
V
T
F
L
L
F
L
M
A
LTG
N
A
L
L
I
L
L
IHSEPRLH
T
P
M
Y
F
F
I
S
Q
L
A
L
M
D
L
M
Y
L
C
V
T
-
V
P
K
M
L
V
G
QVTGDDTISPSGC
G
I
Q
M
F
F
Y
L
T
LAG
A
-
E
V
F
L
L
A
A
M
A
Y
D
R
Y
A
A
V
C
R
PL-H
Y
P
L
L
M
N
Q
R
V
C
Q
L
L
V
S
A
C
W
V
L
G
M
VDG
L
L
LT
P
I
TMSFPFCQS
R
K
I
L
S
F
F
CET
P
A
L
L
K
L
SC-------
S
-------
D
V
S
L
Y
K
T
L
M
Y
L
C
C
I
L
M
L
L
A
P
I
M
V
ISS
S
Y
T
L
I
L
----
H
L
I
H
----
R
----
M
N
SA-----------A--------------------G
H
R
------
K
A
L
A
T
CSS
H
M
I
I
V
-------
L
L
L
F--------GAS
F
Y
T
Y
MLPSSYH---
T
A
-------
E
-------
Q
D
--
M
M
V
S
A
F
Y
T
I
F
T
P
V
L
N
P
L
I
Y
S
LRN
K
D
V
T
R
A
L
R
S
M
M
---
Q
S
R
MNQEK----------------
9
PsiBlast_PDB
93.86
22%
-158
- C1 -
4UG2
3
?
A:
[11-309]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
K
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
LF-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
L
A
A
R
----
R
Q
L-----------------------------------------A
R
S
T
L
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
R
------------------
8
PsiBlast_PDB
93.36
22%
-158
- C1 -
2YDV
6
?
A:
[11-311]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
K
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
LF-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
L
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
-----------------------------------S
T
L
Q
--
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
R
Q
Q
----------------
10
PsiBlast_PDB
93.16
22%
-158
- C1 -
4UHR
1
AA2AR_HUMAN
A:
[11-311]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
K
E
G
K
A
---
G
C
G
E
G
Q
V
A
C
LF-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
L
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
-
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
R
Q
Q
----------------
7
PsiBlast_PDB
92.95
22%
-158
- C1 -
2YDO
3
?
A:
[11-311]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
K
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
LF-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
L
A
A
R
----
R
Q
L
K
Q
M
E
S
------------------------------------T
L
Q
---
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
R
Q
Q
----------------
4
PsiBlast_PDB
92.38
23%
-173
- C1 -
3UZA
1
AA2AR_HUMAN
A:
[11-305]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
A
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
----------------------
40
Fugue
92.33
20%
-131
- C1 -
1F88
8
OPSD_BOVIN
A:
[1-348]
MN
G
T
E
G
PN
F
Y
V
P
F
S
N
K
T
G
V
V
R
S
P
F
E
A
P
Q
Y
Y
----------
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
-
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
-
S
-
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---
A
P
P
L
V
G
W
----
S
R
-------
Y
I
P
E
G
M
Q
C
S
C
-------
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
----
E
----
A
A
A
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
--------
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
---
F
T
-------
H
QGSDFGP
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
P
S
T
TVSKTETS
Q
V
A
P
A---
12
PsiBlast_PDB
91.63
22%
-170
- C1 -
3VGA
1
AA2AR_HUMAN
A:
[11-308]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
----
Q
----
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
-------------------
3
PsiBlast_PDB
91.62
23%
-169
- C1 -
3RFM
1
AA2AR_HUMAN
A:
[11-305]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
A
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
----------------------
11
PsiBlast_PDB
91.55
22%
-171
- C1 -
3VG9
8
?
A:
[11-309]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
----
Q
----
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
H
V
L
R
------------------
2
PsiBlast_PDB
91.28
23%
-173
- C1 -
3REY
1
AA2AR_HUMAN
A:
[11-305]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
A
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
----------------------
1
PsiBlast_PDB
91.13
23%
-174
- C1 -
3PWH
1
?
A:
[11-305]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
LF-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
A
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
----------------------
5
PsiBlast_PDB
90.91
23%
-171
- C1 -
3UZC
1
AA2AR_HUMAN
A:
[11-305]
---------------------------------------------------
T
V
E
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
-
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
-
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
I
G
--
L
T
P
M
-
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
-----
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
----
A
A
A
R
----
R
Q
L
K
Q
M
E
S
Q
PL---------
P
--------------------
G
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
--------
I
I
N
C
F
T
F
F
C
P
D
C
S
H
---
A
P
-------
L
-------
W
L
--
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---
R
S
----------------------
41
Fugue
88.07
20%
-109
- C1 -
1U19
15
OPSD_BOVIN
A:
[4-349]
----------
M
N
G
T
E
G
P
N
F
Y
V
P
F
S
N
K
T
G
V
V
RSPFEAPQYY
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
-
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
-
S
-
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
---
P
P
L
V
G
W
----
S
R
-------
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTP
H
-------
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
----
E
----
A
A
A
Q
QQES-------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
--------
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
---
F
T
H
QGSDFG
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
CG
K
N
P
L
G
D
D
E
A
S
T
T
V
S
K
TETSQVAPA
34
HHSearch
86.26
16%
-158
* C1 *
2Z73
5
OPSD_TODPA
A:
[34-332]
----------------------------------------------
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
-
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
-
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
---
Y
T
-
L
E
G
V
L
C
N
C
S
F
D
Y
I
S
R
-------------------
D
S
T
T
R
S
N
I
L
C
M
F
I
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
----
M
S
V
S
----
N
----
H
E
K
E
-----------
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
M
------
R
L
A
K
I
S
I
V
I
V
S
Q
F
-------
L
L
S
W
--------
S
P
Y
A
V
V
A
L
L
A
Q
F
G
P
LEW
V
T
-------
P
-------
Y
A
--
A
Q
L
P
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
---
P
W
V
L
T
C
C
Q
----------------
15
PsiBlast_PDB
86.20
21%
-155
- C1 -
3C9L
13
OPSD_BOVIN
A:
[32-312]
-----------------------------------------
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
-
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
--
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-------
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
EAAA
Q
----
Q
Q
E
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
---
F
G
-------
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
D
D
E
----------------
17
PsiBlast_PDB
85.32
21%
-153
- C1 -
3DQB
5
GNAT1_BOVIN (first)
A:
[32-312]
-----------------------------------------
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
-
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
--
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-------
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
E
A
A
A
Q
----
Q
Q
E
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
---
F
G
-------
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
-------------------
14
PsiBlast_PDB
84.48
21%
-153
- C1 -
3CAP
6
OPSD_BOVIN
A:
[32-312]
-----------------------------------------
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
-
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
--
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-------
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
E
A
A
A
Q
----
Q
Q
E
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
---
F
G
-------
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
-------------------
19
PsiBlast_PDB
83.48
21%
-156
- C1 -
3PXO
4
OPSD_BOVIN
A:
[32-312]
-----------------------------------------
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
-
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
--
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-------
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
E
A
A
A
Q
----
Q
Q
E
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
---
F
G
-------
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
-------------------
16
PsiBlast_PDB
83.43
21%
-152
- C1 -
1F88
7
OPSD_BOVIN
A:
[32-312]
-----------------------------------------
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
-
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
--
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-------
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
----
F
T
V
K
EAAA--------
S
-----------
A
--------------------
T
T
Q
------
K
A
E
K
E
V
T
R
M
V
I
I
M
-------
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
---
F
G
-------
P
-------
I
F
--
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---
C
C
G
K
N
P
S
T
----------------
30
HHSearch
83.34
16%
-152
- C1 -
2KS9
1
NK1R_HUMAN
A:
[34-324]
------------------------------------------------
L
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
N
F
F
P
I
A
A
V
F
A
-
S
I
Y
S
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
-
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
---
T
T
-
E
-
T
M
P
S
R
V
V
C
M
I
E
W
P
E
H
P
N
-----------------
K
I
Y
E
K
V
Y
H
I
C
V
T
V
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
----
I
T
L
W
----
A
----
S
E
I
P
GDSSDRYH
E
Q
V
S
--------------------
A
K
R
------
K
V
V
K
M
M
I
V
V
V
C
T
F
-------
A
I
C
W
--------
L
P
F
H
I
F
F
L
L
P
Y
I
N
P
---
D
L
YLK----
K
F------
I
Q
Q
V
Y
L
A
I
M
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
---
R
C
C
P
F
I
S
A
----------------