@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AKT3_HUMAN: (2013-07-19 )
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE

Atome Classification :

(71 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.----...--.....150.....-..160.....---.---.---170----........180.......190.......-200--.-.-......210.......220.......230.......--240--.........250.......260..-..--...270.......280........290.......300.-..--.....310.......-----320--.----.......330.......340-....-----.--..----350.-......--360-----......--.---.370.......380.......390.....-...400.......---410.......420......-----.430.....--..440.......450.......460.......470.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHH--K----RKT--MNDFDYLKLLGKG-TFGKVILVRE---K---A---S-G----KYYAMKILKKEVIIAKDEVAHTLTESRV-L-K--N-T-RHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR--E----RVFSEDRTRFYGAEIVSALDYLHS-GK--IVYRDLKLENLMLD-KDGHIKITDFGLCKEGITDA-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------DIKFPR--T---LSSDAKSLLSGLLIKDPNKRLGG-GPDDA-KEIMRHSFFSGVN---WQDVYDKKLVPPFKPQVTS-----ETDTRYFDE--EFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
88 HHSearch 94.3483%-107 - C1 -4EJN AKT1_HUMAN A:[4-438] ---VAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERP------APLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADG---------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIV-------------V-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHSEKN--VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIK-------K--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYF----------------------------------------------
89 HHSearch 85.6486%-107 - C1 -4GV1 AKT1_HUMAN A:[3-337] ----------------------------------------------------------------------------------------------------------------------------------------------S----RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHSEKN--VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMITITP-------SMECVDSERRPHFPQFDYSAS---
16 PsiBlast_PDB 85.6082%-109 - C1 -3E87 AKT2_HUMAN A:[3-335] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSITITPP--------------QRTHFPQFDYSASIR-
3 PsiBlast_PDB 84.6785%-106 - C1 -3OCB AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQM---------------------RPHFPQFDYSAS---
8 PsiBlast_PDB 84.5285%-104 - C1 -4EKK AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMI-----------------SERRPHFPQFDYSAS---
17 PsiBlast_PDB 84.4882%-110 - C1 -3E88 AKT2_HUMAN A:[3-335] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSITIT----------------QRTHFPQFDYSASIR-
6 PsiBlast_PDB 84.4085%-105 - C1 -3QKL AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMIT-------------------RPHFPQFDYSAS---
13 PsiBlast_PDB 84.3185%-104 - C1 -3MVH AKT1_HUMAN A:[7-338] ----------------------------------------------------------------------------------------------------------------------------------------------------VT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQ----------------------RPHFPQFDYSA----
12 PsiBlast_PDB 84.1585%-105 - C1 -3MV5 AKT1_HUMAN A:[6-339] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMI--------------------RPHFPQFDYSAS---
15 PsiBlast_PDB 84.0783%-110 - C1 -1O6K AKT2_HUMAN A:[3-334] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT------------------QRTHFPQFDYSASI--
18 PsiBlast_PDB 83.8282%-111 - C1 -3E8D AKT2_HUMAN A:[3-335] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT---------------------HFPQFDYSASIR-
4 PsiBlast_PDB 83.6085%-104 - C1 -3OW4 AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMIT-------------------RPHFPQFDYSAS---
91 HHSearch 83.2381%-108 - C1 -1O6L AKT2_HUMAN A:[1-336] ---------------------------------------------------------------------------------------------------------------------------------------------------KVT--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT-------------------QEMFEDFDYIAD---
19 PsiBlast_PDB 83.2282%-108 - C1 -3D0E AKT2_HUMAN A:[3-335] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSITITPPD-------------QRTHFPQFDYSASIR-
9 PsiBlast_PDB 83.1885%-103 - C1 -4EKL AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMITITP-------SMECVDSERRPHFPQFDYSAS---
7 PsiBlast_PDB 83.0785%-106 - C1 -3QKM AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMITITP-------SMECVDSERRPHFPQFDYSAS---
5 PsiBlast_PDB 82.9085%-102 - C1 -3QKK AKT1_HUMAN A:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMITI----------MECVDSERRPHFPQFDYSAS---
11 PsiBlast_PDB 82.8485%-107 - C1 -3CQW AKT1_HUMAN A:[6-339] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK--TFCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMI------------------ERRPHFPQFDYSAS---
29 PsiBlast_CBE 72.0981% -66 - C1 -2JDO AKT2_HUMAN A:[8-340] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT---------------------MFEDFDYIA----
21 PsiBlast_CBE 71.9485% -64 - C1 -4EKK AKT1_HUMAN B:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMI-----------------SERRPHFPQFDYSAS---
24 PsiBlast_CBE 71.9382% -64 - C1 -3E8D AKT2_HUMAN B:[3-335] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSI-------------------QRTHFPQFDYSASIR-
27 PsiBlast_CBE 71.5381% -64 - C1 -2UW9 AKT2_HUMAN A:[8-340] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT-------------------QEMFEDFDYIA----
22 PsiBlast_CBE 71.3785% -62 - C1 -3OW4 AKT1_HUMAN B:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMIT-------------------RPHFPQFDYSAS---
25 PsiBlast_CBE 71.0881% -68 - C1 -2XH5 AKT2_HUMAN A:[8-340] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT-------------------QEMFEDFDYIA----
26 PsiBlast_CBE 70.8481% -65 - C1 -2X39 AKT2_HUMAN A:[8-340] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT-------------------QEMFEDFDYIA----
28 PsiBlast_CBE 70.5681% -62 - C1 -2JDR AKT2_HUMAN A:[8-340] -----------------------------------------------------------------------------------------------------------------------------------------------------T--MNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-L-Q--N-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--E----RVFTEERARFYGAEIVSALEYLHS-RD--VVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHER-LFELIL--ME------EIRFPR--T---LSPEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDD--EFTAQSIT-------------------QEMFEDFDYIA----
102 HHSearch 69.9938% -92 - C1 -4AW2 MRCKA_RAT A:[70-407] ---------------------------------------------------------------------------------------------------------------------------------------------------RLH--REDFEILKVIGRG-AFGEVAVVKL---K---N---A-D----KVFAMKILNKWEMLKRAETACFREERDV-L-V--N-G-DSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKF-E----DRLPEEMARFYLAEMVIAIDSVHQ-LH--YVHRDIKPDNILMD-MNGHIRLADFGSCLKLMEDG-TVQSS--VAVGTPDYISPEILQAMEGGKG---R----YGPECDWWSLGVCMYEMLYG-ETPF-----Y--AE----SLVE-TYGKIM--NHKE----RFQFPT--QVTDVSENAKDLIRRLICSRE-HRLG---QNGI-EDFKKHPFFSGID---WDNI--RNCEAPYIPEVSS-----PTDTSNFDV--D-----------------------SGHHLPFVGFTYTSSC--
23 PsiBlast_CBE 69.9085% -58 - C1 -3OCB AKT1_HUMAN B:[5-338] ---------------------------------------------------------------------------------------------------------------------------------------------------RVT--MNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-L-Q--N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--E----RVFSEDRARFYGAEIVSALDYLHS-EKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDG-AT-MK---FCGTPEYLAPEVLE-----DN---D----YGRAVDWWGLGVVMYEMMCG-RLPF-----Y--NQ----DHEK-LFELIL--ME------EIRFPR--T---LGPEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDE--EFTAQMITIT-----------------RPHFPQFDYSAS---
97 HHSearch 69.7545%-105 - C1 -1XJD A:[16-335] --------------------------------------------------------------------------------------------------------------------------------------------------------IEDFILHKMLGKG-SFGKVFLAEF---K---K---T-N----QFFAIKALKKDVVLMDDDVECTMVEKRV-L-S--L-AWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS--C----HKFDLSRATFYAAEIILGLQFLHS-KG--IVYRDLKLDNILLD-KDGHIKIADFGMCKENMLGD-AK-TN--TFCGTPDYIAPEILL-----GQ---K----YNHSVDWWSFGVLLYEMLIG-QSPF-----H--GQ----DEEE-LFHSIR--MD------NPFYPR--W---LEKEAKDLLVKLFVREPEKRLGV-R-----GDIRQHPLFREIN---WEELERKEIDP---------------------------------------------------QNMFRNFSF------
34 PsiBlast_CBE 68.4645%-104 - C1 -4DC2 KPCI_MOUSE A:[49-363] ------------------------------------------------------------------------------------------------------------------------------------------------------LGLQDFDLLRVIGRG-SYAKVLLVRL---K---K---T-D----RIYAMRVVKKELVN----IDWVQTEKHV-F-E--QAS-NHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQR--Q----RKLPEEHARFYSAEISLALNYLHE-RG--IIYRDLKLDNVLLD-SEGHIKLTDYGMCKEGLRPG-DT-TS--TFCGTPNYIAPEILR-----GE---D----YGFSVDWWALGVLMFEMMAG-RSPFDIVGS---------NTEDYLFQVIL--EK------QIRIPR--S---LSVKAASVLKSFLNKDPKERLGC-HPQTGFADIQGHPFFRNVD---WDMMEQKQVVPPFKPNISG-----EFGLDNFDS--QFTNEPVQL---------------------------------
105 HHSearch 67.2043% -90 - C1 -1RDQ KAPCA_MOUSE E:[34-341] ------------------------------------------------------------------------------------------------------------------------------------------SQ--N----TAQ--LDQFDRIKTLGTG-SFGRVMLVKH---K---E---S-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRV---K-GR-TW--TLCGTPEALAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINE-----------------------------
42 PsiBlast_CBE 66.0245%-105 - C1 -2Z7Q KS6A1_HUMAN A:[24-308] ---------------------------------------------------------------------------------------------------------------------------------------------------KAD--PSHFELLKVLGQG-SFGKVFLVRK---V---TRPDS-G----HLYAMKVL-------------------I-L-A--D-V-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK--E----VMFTEEDVKFYLAELALGLDHLHS-LG--IIYRDLKPENILLD-EEGHIKLTDFGLSKE----------------GTVEYMAPEVVN-----RQ---G----HSHSADWWSYGVLMFEMLTG-SLPF-----Q--GK----DRKE-TMTLIL--KA------KLGMPQ--F---LSTEAQSLLRALFKRNPANRLGS-GPDGA-EEIKRHVFYSTID---WNKLYRREIKPPFKP--------------------------------------------------------------
51 PsiBlast_CBE 65.9641% -89 - C1 -2UZT KAPCA_BOVIN A:[11-328] -----------------------------------------------------------------------------------------------------------------------------DFLKKWENPAQNTAH------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRV---K-GR-TW--TLCGTPEYLAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINEK----------------------------
104 HHSearch 65.6335% -91 - C1 -3C4Z RK_BOVIN A:[180-510] ----------------------------------------------------------------------------------------------------------------------------------------------Q----PMG--EDWFLDFRVLGRG-GFGEVFACQM---K---A---T-G----KLYACKKLNKKRLKKRKGYQGAMVEKKI-L-A--K-V-HSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYN--VDEDNPGFQEPRAIFYTAQIVSGLEHLHQ-RN--IIYRDLKPENVLLD-DDGNVRISDLGLAVELKAGQ-TK-TK--GYAGTPGFMAPELLL-----GE---E----YDFSVDYFALGVTLYEMIAA-RGPF-----R--ARGEKVENKE-LKQRVL--EQ------AVTYPD--K---FSPASKDFCEALLQKDPEKRLGF-RDGSC-DGLRTHPLFRDIS---WRQLEAGMLTPPFVPDSRTVYAKN----GAFS--------GVAFE--------------KADTEFFQEFASGT----
94 HHSearch 65.5150%-111 - C1 -2R5T SGK1_HUMAN A:[30-320] -----------------------------------------------------------------------------------------------------------------------------------------SSN--P----HAK--PSDFHFLKVIGKG-SFGKVLLARH---K---A---E-E----VFYAVKVLQKKAIL-------------VLL-K--N-V-KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--E----RCFLEPRARFYAAEIASALGYLHS-LN--IVYRDLKPENILLD-SQGHIVLTDFGLCKENIEHN-ST-TS--TFCGTPEYLAPEVLH-----KQ---P----YDRTVDWWCLGAVLYEMLYG-LPPF-----Y--SR----NTAE-MYDNIL--NK------PLQLKP--N---ITNSARHLLEGLLQKDRTKRLGA-K-DDF-MEIKSHVFFSLIN---WDDLINKKITPPFNPNVSG----------------------------------------------------------
95 HHSearch 65.4645% -90 - C1 -3TXO KPCL_HUMAN A:[23-349] ---------------------------------------------------------------------------------------------------------------------------------------------------------DNFEFIRVLGKG-SFGKVMLARV---K---E---T-G----DLYAVKVLKKDVILQDDDVECTMTEKRI-L-S--L-ARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQK--S----RRFDEARARFYAAEIISALMFLHD-KG--IIYRDLKLDNVLLD-HEGHCKLADFGMCKEGIC-------------GTPDYIAPEILQ-----EM---L----YGPAVDWWAMGVLLYEMLCG-HAPF-----E--AE----NEDD-LFEAIL--ND------EVVYPT--W---LHEDATGILKSFMTKNPTMRLGSLTQGGE-HAILRHPFFKEID---WAQLNHRQIEPPFRPRIKS-----REDVSNFDP--DFIKEEPVLTPIDEGHL---P---MINQDEFRNFEYVSP---
71 PsiBlast_CBE 65.4340%-103 - C1 -2ACX GRK6_HUMAN A:[182-467] -----------------------------------------------------------------------------------------------------------------------------------------------------T--KNTFRQYRVLGKG-GFGEVCACQV---R---A---T-G----KMYACKKLEKKRIKKRKGEAMALNEKQI-L-E--K-V-NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQ----AGFPEARAVFYAAEICCGLEDLHR-ER--IVYRDLKPENILLD-DHGHIRISDLGLAVH-VPEG-QT-IK--GRVGTVGYMAPEVVK-----NE---R----YTFSPDWWALGCLLYEMIAG-QSPF-----Q--QRKKKIKREE-VERLVK--EV------PEEYSE--R---FSPQARSLCSQLLCKDPAERLGC-RGGSA-REVKEHPLFKKLN---FKRLGAGMLEPPFKP--------------------------------------------------------------
78 PsiBlast_CBE 65.3133% -82 - C1 -3D9V ROCK1_HUMAN B:[42-402] ---------------------------------------------------------------------------------------------------------------------DFPALRKNKNIDNFLSRYKDTIN--KIRDLRMK--AEDYEVVKVIGRG-AFGEVQLVRH---K---S---T-R----KVYAMKLLSKFEMIKRSDSAFFWEERDI-M-A--F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN--Y----DV-PEKWARFYTAEVVLALDAIHS-MG--FIHRDVKPDNMLLD-KSGHLKLADFGTCMKMNKEGMVR-CD--TAVGTPDYISPEVLK-----SQ---GGDGYYGRECDWWSVGVFLYEMLVG-DTPF-----Y--AD----SLVG-TYSKIMNHKN------SLTFPDDND---ISKEAKNLICAFLT-DREVRLG---RNGV-EEIKRHLFFKNDQ---WAWETLRDTVAPVVPDLSS-----DIDTSNFDDLEEDKGEEETFPIPKAFVGNQLP---------FVGFTYYSN---
48 PsiBlast_CBE 65.2741% -86 - C1 -2UZW KAPCA_BOVIN E:[11-328] -----------------------------------------------------------------------------------------------------------------------------DFLKKWENPAQNTAH------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRV---K-GR-TW--TLCGTPEYLAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINEK----------------------------
70 PsiBlast_CBE 65.2040%-103 - C1 -2ACX GRK6_HUMAN B:[182-467] -----------------------------------------------------------------------------------------------------------------------------------------------------T--KNTFRQYRVLGKG-GFGEVCACQV---R---A---T-G----KMYACKKLEKKRIKKRKGEAMALNEKQI-L-E--K-V-NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHM------AGFPEARAVFYAAEICCGLEDLHR-ER--IVYRDLKPENILLD-DHGHIRISDLGLAVH-VPEG-QT-IK--GRVGTVGYMAPEVVK-----NE---R----YTFSPDWWALGCLLYEMIAG-QSPF-----Q--Q-KI--KREE-VERLVK--EV------PEEYSE--R---FSPQARSLCSQLLCKDPAERLGC-RGGSA-REVKEHPLFKKLN---FKRLGAGMLEPPFKP--------------------------------------------------------------
40 PsiBlast_CBE 65.1545%-104 - C1 -2Z7S KS6A1_HUMAN A:[24-308] ---------------------------------------------------------------------------------------------------------------------------------------------------KAD--PSHFELLKVLGQG-SFGKVFLVRK---V---TRPDS-G----HLYAMKVLK------------------I-L-A--D-V-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK--E----VMFTEEDVKFYLAELALGLDHLHS-LG--IIYRDLKPENILLD-EEGHIKLTDFGLSKE----------------GTVEYMAPEVVN-----RQ---G----HSHSADWWSYGVLMFEMLTG-SLPF-----Q--GK----DRKE-TMTLIL--KA------KLGMPQ--F---LSTEAQSLLRALFKRNPANRLGS-GPDGA-EEIKRHVFYSTID---WNKLYRREIKPPFKP--------------------------------------------------------------
56 PsiBlast_CBE 65.0139% -82 - C1 -2F7E KAPCA_BOVIN E:[16-343] -------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQNTAH------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKR---VK-GR-TW--TLCGTPEYLAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINEK----------------------------
117 Fugue 64.6040% -90 - C1 -1CDK KAPCA_PIG A:[8-350] -------------------------------------------------------------------------------------------KGSEQESVKEFLAKAKEDFLKKWENPAQNTA-------------------------H----LDQFERIKTLGT-GSFGRVMLVKH---K---E---TG-----NHFAMKILDKQKVVKLKQIEHTLNEKRI-L-QAV----NFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRI------GRFSEPHARFYAAQIVLTFEYLHS---LDLIYRDLKPENLLIDQ-QGYIQVTDFGFAKRV-K---G---RTWTLCGTPEYLAPEIIL-----S-KGY------NKAVDWWALGVLIYEMAAGY-PPF-----FAD------QPIQ-IYEKIV--SGKVRFPS--------H---FSSDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFA---TTDWIAIYQRKVEAPFIPKFKG-----PGDTSNFDD--YEEEEIRVSI-------------NEKCGKEFSEF--------
52 PsiBlast_CBE 64.4039% -82 - C1 -2OJF KAPCA_BOVIN E:[16-343] -------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQNTAH------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKR---VK-GR-TW--TLCGTPEYLAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINEK----------------------------
50 PsiBlast_CBE 64.3441% -84 - C1 -2UZU KAPCA_BOVIN E:[11-328] -----------------------------------------------------------------------------------------------------------------------------DFLKKWENPAQNTAH------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-L-Q--A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR--I----GRFSEPHARFYAAQIVLTFEYLHS-LD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRV---K-GR-TW--TLCGTPEYLAPEIIL-----SK---G----YNKAVDWWALGVLIYEMAAG-YPPF-----F--AD----QPIQ-IYEKIV--SG------KVRFPS--H---FSSDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD---DYEEEEIRVSINEK----------------------------