@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AURKA_HUMAN: (2013-07-19 )
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS

Atome Classification :

(89 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.---......160.......170.......180......-.190.......200.......210.......220.....-..230.......240.......250........260.......---270......--.280.--......-..290.......300.......310.......320.......330.......340......--.350-........360.......370-----.-----.------.-....380.......---390.......400.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRT-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PSNCQNKESASKQS
22 PsiBlast_CBE 91.44100%-128 - C1 -3EFW AURKA_HUMAN A:[126-388] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADF------------------------LDYLPPEMIE------KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
125 HHSearch 91.34100%-115 - C1 -3FDN AURKA_HUMAN A:[4-272] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A-----------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PSNCQ---------
60 PsiBlast_CBE 91.32100%-128 - C1 -2X81 AURKA_HUMAN A:[8-269] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLG---FGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIA------------------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
16 PsiBlast_PDB 90.4699%-111 - C1 -3UOD AURKA_HUMAN A:[2-267] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
36 PsiBlast_CBE 90.3199%-113 - C1 -3UP2 AURKA_HUMAN A:[2-267] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
72 PsiBlast_CBE 90.1199%-120 - C1 -3H0Z AURKA_HUMAN A:[5-265] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--------------------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
14 PsiBlast_PDB 90.0399%-113 - C1 -3UO5 AURKA_HUMAN A:[2-268] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---P-------------
65 PsiBlast_CBE 89.66100%-117 - C1 -3O50 AURKA_HUMAN A:[2-264] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGW---------------------TLDYLPPEMIE---HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
43 PsiBlast_CBE 89.4199%-115 - C1 -3K5U AURKA_HUMAN A:[4-272] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--------------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PSNCQ---------
54 PsiBlast_CBE 89.1599%-118 - C1 -3LAU AURKA_HUMAN A:[2-268] ----------------------------------------------------------------------------------------------------------------------------KRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADF------------------------LDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
31 PsiBlast_CBE 89.1099%-106 - C1 -4DEE AURKA_HUMAN A:[2-272] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PSNCQ---------
66 PsiBlast_CBE 89.0699%-122 - C1 -3P9J AURKA_HUMAN A:[3-265] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--V----------------GTLDYLPPEMIEG---DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
62 PsiBlast_CBE 88.79100%-114 - C1 -1MQ4 AURKA_HUMAN A:[7-269] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSR---TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
68 PsiBlast_CBE 88.6299%-108 - C1 -3H10 AURKA_HUMAN B:[2-268] ----------------------------------------------------------------------------------------------------------------------------KRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRA-ALCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
52 PsiBlast_CBE 88.59100%-113 - C1 -4JAJ ? A:[13-277] ----------------------------------------------------------------------------------------------------------------------------KRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRT-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
29 PsiBlast_CBE 88.5899%-119 - C1 -4JBQ ? A:[4-269] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--------------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
70 PsiBlast_CBE 88.5499%-121 - C1 -3H0Z AURKA_HUMAN C:[3-265] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIAD------------------------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
59 PsiBlast_CBE 88.50100%-117 - C1 -3MYG AURKA_HUMAN A:[7-269] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH----------------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
73 PsiBlast_CBE 88.3599%-120 - C1 -3H0Y AURKA_HUMAN A:[3-265] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--------------------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
69 PsiBlast_CBE 87.9899%-106 - C1 -3H10 AURKA_HUMAN A:[2-268] ----------------------------------------------------------------------------------------------------------------------------KRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRA-ALCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
21 PsiBlast_CBE 87.96100%-122 - C1 -3EFW AURKA_HUMAN B:[126-389] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADF------------------------LDYLPPEMIE-----EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
57 PsiBlast_CBE 87.66100%-115 - C1 -2W1E AURKA_HUMAN A:[7-269] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--V----------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
33 PsiBlast_CBE 87.5799%-110 - C1 -4DEB AURKA_HUMAN A:[3-266] ----------------------------------------------------------------------------------------------------------------------------KRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
84 PsiBlast_CBE 87.5594%-117 - C1 -3DJ7 AURKA_MOUSE A:[7-269] -----------------------------------------------------------------------------------------------------------------------------RQWTLEDFDIGRPLGKGKFGNVYLARER---QSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSR-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSNGE---LKIADFGWS--VH--A--PS-------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTF--PDF--VTEGARDLISRLLKHNASQRL-----T-----L------A-EVLEHPWIKANSS------------------
74 PsiBlast_CBE 87.5599%-117 - C1 -4DHF AURKA_HUMAN B:[8-269] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSR-----CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
83 PsiBlast_CBE 87.2897%-114 - C1 -3COH AURKA_HUMAN A:[5-265] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---NSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDSTRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-KVIHRDIKPENLLLGSAGE---LKIAD---------------------LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQDTYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
6 PsiBlast_PDB 87.18100%-116 - C1 -2X6D AURKA_HUMAN A:[8-270] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLE----EHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSR-----CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
30 PsiBlast_CBE 87.0599%-109 - C1 -4JBO ? A:[4-269] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRT-DLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
76 PsiBlast_CBE 87.0499%-113 - C1 -3R22 AURKA_HUMAN A:[6-269] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
58 PsiBlast_CBE 87.04100%-118 - C1 -2W1D AURKA_HUMAN A:[7-269] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--V----------------GTLDYLPPEMIEGRMHD-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
77 PsiBlast_CBE 87.0399%-117 - C1 -3R21 AURKA_HUMAN A:[7-269] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--V--------------LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
11 PsiBlast_PDB 87.0298%-115 - C1 -2WTW AURKA_HUMAN A:[10-271] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PS-------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
34 PsiBlast_CBE 86.8999%-110 - C1 -4DEA AURKA_HUMAN A:[2-267] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
78 PsiBlast_CBE 86.8799%-117 - C1 -2W1G AURKA_HUMAN A:[7-269] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
82 PsiBlast_CBE 86.7897%-115 - C1 -3COH AURKA_HUMAN B:[5-265] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---NSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDSTRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-KVIHRDIKPENLLLGSAGE---LKIAD---------------------LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQDTYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
75 PsiBlast_CBE 86.6499%-114 - C1 -4DHF AURKA_HUMAN A:[8-269] -------------------------------------------------------------------------------------------------------------------------------WALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSR-----CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
56 PsiBlast_CBE 86.5299%-115 - C1 -2XNE AURKA_HUMAN A:[7-268] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLF-------GVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIANFGWS--VH--A--P----------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
49 PsiBlast_CBE 86.4499%-111 - C1 -3NRM AURKA_HUMAN A:[6-268] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRA-ALCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
45 PsiBlast_CBE 86.4399%-115 - C1 -2C6E AURKA_HUMAN B:[9-270] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIAD-----------------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
13 PsiBlast_PDB 86.2299%-110 - C1 -3UO4 AURKA_HUMAN A:[2-267] ---------------------------------------------------------------------------------------------------------------------------KKRQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
40 PsiBlast_CBE 86.1399%-109 - C1 -3UOH AURKA_HUMAN B:[4-267] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
63 PsiBlast_CBE 86.11100%-126 - C1 -3O51 AURKA_HUMAN A:[2-264] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADF------------------------LDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
17 PsiBlast_PDB 86.0299%-109 - C1 -3UOH AURKA_HUMAN A:[4-267] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
71 PsiBlast_CBE 85.9299%-119 - C1 -3H0Z AURKA_HUMAN B:[3-265] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLG------VYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIAD------------------------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
88 PsiBlast_CBE 85.8594%-116 - C1 -3D15 AURKA_MOUSE A:[7-269] -----------------------------------------------------------------------------------------------------------------------------RQWTLEDFDIGRPLGKGKFGNVYLARER---QSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSR-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSNGE---LKIADFGWS--VH--A--PS--------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTF--PDF--VTEGARDLISRLLKHNASQRL-----T-----L------A-EVLEHPWIKANSS------------------
5 PsiBlast_PDB 85.85100%-113 - C1 -4B0G AURKA_HUMAN A:[6-271] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQL----VEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--V-----------------TLDYLPPEMIE---HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK---PS------------
86 PsiBlast_CBE 85.8194%-126 - C1 -3DJ5 AURKA_MOUSE A:[9-269] -------------------------------------------------------------------------------------------------------------------------------WTLEDFDIGRPLGKGKFGNVYLARER---QSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSR-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSNGE---LKIADFGW---------------T-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTF--PDF--VTEGARDLISRLLKHNASQRL-----T-----L------A-EVLEHPWIKANSS------------------
46 PsiBlast_CBE 85.5699%-116 - C1 -2C6E AURKA_HUMAN A:[9-271] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS-------------------GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
87 PsiBlast_CBE 85.4594%-118 - C1 -3D2I AURKA_MOUSE A:[8-269] ------------------------------------------------------------------------------------------------------------------------------QWTLEDFDIGRPLGKGKFGNVYLARER---QSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSR-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSNGE---LKIADFGWS--VH--A--P--------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTF--PDF--VTEGARDLISRLLKHNASQRL-----T-----L------A-EVLEHPWIKANSS------------------
41 PsiBlast_CBE 85.3999%-107 - C1 -3UO6 AURKA_HUMAN B:[4-267] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------
67 PsiBlast_CBE 85.3599%-111 - C1 -3H10 AURKA_HUMAN D:[3-265] -----------------------------------------------------------------------------------------------------------------------------RQWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PS---------TLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSS------------------
37 PsiBlast_CBE 85.2399%-109 - C1 -3UOL AURKA_HUMAN B:[5-267] ------------------------------------------------------------------------------------------------------------------------------QWALEDFEIGRPLGKGKFGNVYLAREK---QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK-RVIHRDIKPENLLLGSAGE---LKIADFGWS--VH--A--PSSRRD-TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF--PDF--VTEGARDLISRLLKHNPSQRP-----M-----L------R-EVLEHPWITANSSK-----------------