@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : BRSK1_HUMAN: (2013-07-19 )
MSSGAKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRRGPPKDKKLLATNGTPLP

Atome Classification :

(70 SA) .........10........20......--..30........40........50........60...--.....70.-----..----......---80.......-.-90........100.......110.......120.......130-.........140.......-150.......160.---.---...---.----.---170.....-.-.-180.....-...190........200......-----.210.......220.......230.......240....--.--..250.----..--....-------..260---........270..-----.-----.------...280..---.--------....290.......300....---...310.......320...-....330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSSGAKEGGGGSPAYHLPHPHPHPPQH--AQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKI--VNREKL-S-----ES----VLMKVE---REIAILKLI-E-HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP---KEARKFFRQIVSALDFCHS-YSICHRDLKPENLL---L---DEK---N----N---IRIADFGM-A-S-L-QVGDSL-LETS-CGSPHYACPEVIKGEKYD-----GRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRG--V--FHM--P----HF--IPPD-------CQSL----LRGMIEVEPEKRL-----S-----L------EQIQKHPW---Y--------LGGKHEPDPCLEPAPGRRVAM---RSLPSNGELDPDVLESMAS-LGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRRGPPKDKKLLATNGTPLP
13 PsiBlast_PDB 80.3950%-129 - C3 -2Y94 AAPK1_RAT A:[15-270] --------------------------------IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKI--LNRQKIRS-----LD----VVGKIR---REIQNLKLF-R-HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDE---KESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L---DAH---M----N---AKIADFGL-S-N-M-MSDGEF-LRTS-CGSPNYAAPEVISGRLYA-----GPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG--I--FYT--P----QY--LNPS-------VISL----LKHMLQVDPMKRA-----T-----I------KDIREHEW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 77.6249%-122 - C3 -3AQV AAPK2_HUMAN A:[10-265] --------------------------------IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKI--LNRQKIRS-----LD----VVGKIK---REIQNLKLF-R-HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE---MEARRLFQQILSAVDYCHR-HMVVHRDLKPENVL---L---DAH---M----N---AKIADFGL-S-N-M-MSDGEF-L-------PNYAAPEVISGRLYA-----GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG--V--FYI--P----EY--LNRS-------VATL----LMHMLQVDPLKRA-----T-----I------KDIREHEW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 75.5336%-115 - C3 -3BHH KCC2B_HUMAN A:[6-290] -----------------------------------YQLYEDIG----SVVRRCVKLCTGHEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIQQILEAVLHCHQ-MGVVHRDLKPENLL---L---ASK---C----KGAAVKLADFGL-A-I-E-VQGDQQ-AWFGFAGTPGYLSPEVLRKEAY------GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKNL----INQMLTINPAKRI-----T-----A------HEALKHPW---VCQRSTVASMMHRQETVECLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 74.6036%-115 - C3 -3BHH KCC2B_HUMAN B:[6-290] -----------------------------------YQLYEDIGK---SVVRRCVKLCTGHEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIQQILEAVLHCHQ-MGVVHRDLKPENLL---L---ASK---C----KGAAVKLADFGL-A-I-E-VQGDQQ-AWFGFAGTPGYLSPEVLRKEAY------GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKNL----INQMLTINPAKRI-----T-----A------HEALKHPW---VCQRSTVASMMHRQETVECLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 74.2642%-120 - C3 -4BL1 MELK_HUMAN A:[3-271] ------------------------KDY--DELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKI--MDKNTL--------------LPRIK---TEIEALKNL-R-HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSE---EETRVVFRQIVSAVAYVHS-QGYAHRDLKPENLL---F---DEY---H----K---LKLIDFGL-C-A-K---------------SLAYAAPELIQGK--------GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRG--K--YDV--P----KW--LSPS-------SILL----LQQMLQVDPKKRI-----S-----M------KNLLNHPW---I--------MQDYNYP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 72.8636%-128 - C3 -2Y7J PHKG2_HUMAN C:[91-363] ------------------------------EFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERL-SPEQL-EE----VREATR---RETHILRQV-AGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSE---KETRSIMRSLLEAVSFLHA-NNIVHRDLKPENIL---L---DDN---M----Q---IRLSDFGF-S-CHL-EPGEKL-REL--CGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEG--Q--Y---------QF--SSPEWDDRSSTVKDL----ISRLLQVDPEARL-----T-----A------EQALQHPF---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 72.4636%-111 - C3 -2VN9 KCC2D_HUMAN B:[6-290] -----------------------------------YQLFEELGKGAFSVVRRCMKIPTGQEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIQQILESVNHCHL-NGIVHRDLKPENLL---L---ASK---S----KGAAVKLADFGL-A-I-E-VQGDQQ-AWFGFAGTPGYLSPEVLRKDPY------GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKDL----INKMLTINPAKRI-----T-----A------SEALKHPW---ICQRSTVASMMHRQETVDCLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 72.4536%-125 - C3 -2WEL KCC2D_HUMAN A:[6-290] -----------------------------------YQLFEELGKGAFSVVRRCMKIPTGQEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIQQILESVNHCHL-NGIVHRDLKPENLL---L---ASK---S----KGAAVKLADFGL-A-I-E-VQGDQQ-AWFGFAGTPGYLSPEVLRKDPY------GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKDL----INKMLTINPAKRI-----T-----A------SEALKHPW---ICQRS----MMHRQETVDCLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 72.2934%-101 - C3 -3SOA KCC2A_HUMAN A:[8-297] ------------------------------RFTEEYQLFEELGKG--SVVRRCVKVLAGQEYAAMI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE---ADASHCIQQILEAVLHCHQ-MGVVHRNLKPENLL---L---ASKLKGA----A---VKLADFGL-A-I-E-VEGEQQ-AWFGFAGTPGYLSPEVLRKDPY------GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKDL----INKMLTINPSKRI-----T-----A------AEALKHPW---ISHRSTVASCMHRQETVDCLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136 HHSearch 72.2441%-127 * C3 *4FG7 KCC1A_HUMAN A:[19-277] ----------------------------------IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IA--------------------SME---NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE---RDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL---DED---S----K---IMISDFGL-S-K-M-EDPG----------TPGYVAPEVLAQK--S------KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA--E--YEF--DSPYWDD--ISDS-------AKDF----IRHLMEKDPEKRF-----T-----C------EQALQHPW---I--------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 72.2236%-111 - C3 -2VN9 KCC2D_HUMAN A:[6-290] -----------------------------------YQLFEELGKGAFSVVRRCMKIPTGQEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIQQILESVNHCHL-NGIVHRDLKPENLL---L---ASK---S----KGAAVKLADFGL-A-I-E-VQGDQQ-AWFGFAGTPGYLSPEVLRKDPY------GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKDL----INKMLTINPAKRI-----T-----A------SEALKHPW---ICQRSTVASMMHRQETVDCLKKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 72.2135%-109 - C3 -2V7O KCC2G_HUMAN A:[28-317] ------------------------------RFTDDYQLFEELGKG-FSVVRRCVKKTPTQEYAAKI--INTKKL-S-----AR----DHQKLE---REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE---ADASHCIHQILESVNHIHQ-HDIVHRDLKPENLL---L---ASK---C----KGAAVKLADFGL-AIE-V-QGEQQA-WFGF-AGTPGYLSPEVLRKDPY------GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAG--A--YDF--PSPEWDT--VTPE-------AKNL----INQMLTINPAKRI-----T-----A------DQALKHPW---VCQRSTVASMMHRQETVECLRKFNARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 70.6234%-107 - C3 -3HZT ? A:[6-335] -----------------------------------YQRVKKLGSGAYGEVLLCKDKLTGAERAIKI--IKKSSV-T-----TTSNSGALLD------EVAVLKQL-D-HPNIMKLYEFFEDKRNYYLVMEVYRGGELFDEIILRQKFSE---VDAAVIMKQVLSGTTYLHK-HNIVHRDLKPENLL---L---ESK---S----RDALIKIVDFGLSA-H-F-EVG-----------TAYYIAPEVLR-KKYD------EKCDVWSCGVILYILLCGYPPFGGQTDQEILKRVEKG--K--F---------SF--DPPDWTQVSDEAKQL----VKLMLTYEPSKRI-----S-----A------EEALNHPWIVKF--------CSQ-----VGKHALTGALGNM---KKFQSSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQ-----LDRKE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134 HHSearch 69.0234%-126 - C3 -4GV1 AKT1_HUMAN A:[9-270] ----------------------------------EFEYLKLLGKGTFGKVILVKEKATGRYYAMKI--LKKEVIVA-----KD----EVAHTL---TENRVLQNS-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSE---DRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM---L---DKD---G----H---IKITDFGL-C-K-EGIKDGAT-MKTF-CGTPEYLAPEVLEDNDY------GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME--E--IRF--P----RT--LGPE-------AKSL----LSGLLKKDPKQRL-----GGGSEDA------KEIMQHRF---F--------AG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103 PsiBlast_CBE 68.4133%-117 - C3 -2F7X KAPCA_BOVIN E:[33-298] ----------------------NPAQN--TAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKI--LDKQKV-V-----K------LKQIEHTLNEKRILQAV-N-FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLL---I---DQQ---G----Y---IQVTDFGF-A-K-R-VKGRTW---TL-CGTPEYLAPEIILSKGYN------KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--K--VRF--P----SH--FSSD-------LKDL----LRNLLQVDLTKRFGNLKNG-----V------NDIKNHKW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104 PsiBlast_CBE 68.2433%-121 - C3 -2F7E KAPCA_BOVIN E:[33-298] ----------------------NPAQN--TAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKI--LDKQKV-V-----K------LKQIEHTLNEKRILQAV-N-FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLL---I---DQQ---G----Y---IQVTDFGF-A-K-R-VKGRTW---TL-CGTPEYLAPEIILSKGYN------KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--K--VRF--P----SH--FSSD-------LKDL----LRNLLQVDLTKRFGNLKNG-----V------NDIKNHKW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115 PsiBlast_CBE 67.6635%-125 - C3 -2YAA DAPK2_MOUSE B:[14-275] -----------------------------------YDIGEELGSGQFAIVKKCREKSTGLEYAAKF--IKKRQS-R-----ASRRGVCREEIE---REVSILRQV-L-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSE---EEATSFIKQILDGVNYLHT-KKIAHFDLKPENIM---L---LDK---NIPIPH---IKLIDFGL-A-H---EIEDGVEFKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANITAV--S--YDFD-E----EF--FSQTSEL----AKDF----IRKLLVKETRKRL-----T-----I------QEALRHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100 PsiBlast_CBE 67.6433%-119 - C3 -2OJF KAPCA_BOVIN E:[33-298] ----------------------NPAQN--TAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKI--LDKQKV-V-----K------LKQIEHTLNEKRILQAV-N-FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLL---I---DQQ---G----Y---IQVTDFGF-A-K-R-VKGRTW---TL-CGTPEYLAPEIILSKGYN------KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--K--VRF--P----SH--FSSD-------LKDL----LRNLLQVDLTKRFGNLKNG-----V------NDIKNHKW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102 PsiBlast_CBE 67.3033%-121 - C3 -2F7Z KAPCA_BOVIN E:[33-298] ----------------------NPAQN--TAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKI--LDKQKV-V-----K------LKQIEHTLNEKRILQAV-N-FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLL---I---DQQ---G----Y---IQVTDFGF-A-K-R-VKGRTW---TL-CGTPEYLAPEIILSKGYN------KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--K--VRF--P----SH--FSSD-------LKDL----LRNLLQVDLTKRFGNLKNG-----V------NDIKNHKW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101 PsiBlast_CBE 66.7633%-121 - C3 -2OH0 KAPCA_BOVIN E:[33-298] ----------------------NPAQN--TAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKI--LDKQKV-V-----K------LKQIEHTLNEKRILQAV-N-FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLL---I---DQQ---G----Y---IQVTDFGF-A-K-R-VKGRTW---TL-CGTPEYLAPEIILSKGYN------KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--K--VRF--P----SH--FSSD-------LKDL----LRNLLQVDLTKRFGNLKNG-----V------NDIKNHKW---F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 PsiBlast_CBE 66.6639%-128 - C3 -4FG8 KCC1A_HUMAN B:[20-278] -----------------------------------YDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAK-------------------------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE---RDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL---DED---S----K---IMISDFG-----------GSV-LSTA-CGTPGYVAPEVLAQKPY------SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA--E--YEFDSP----YWDDISDS-------AKDF----IRHLMEKDPEKRF-----T-----C------EQALQHPW---I--------AG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 66.4737%-122 - C3 -2Y0A DAPK1_HUMAN A:[13-274] -----------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 66.4739%-136 - C3 -4FG9 KCC1A_HUMAN A:[20-278] -----------------------------------YDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAKE--------------------E---NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE---RDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL---DED---S----K---IMISDF------------------------PGYVAPEVLAQKPY------SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA--E--YEFDSP----YWDDISDS-------AKDF----IRHLMEKDPEKRF-----T-----C------EQALQHPW---I--------AG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 65.7937%-118 - C3 -3EH9 DAPK1_HUMAN A:[18-273] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRGV-SREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEK-SLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 65.6639%-140 - C3 -4FG8 KCC1A_HUMAN A:[20-278] -----------------------------------YDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAKE------------------------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE---RDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL---DED---S----K---IMISDF-----------------------TPGYVAPEVLAQKPY------SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA--E--YEFDSP----YWDDISDS-------AKDF----IRHLMEKDPEKRF-----T-----C------EQALQHPW---I--------AG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 65.4236%-126 - C3 -3HX4 ? A:[31-308] --------------DHLHATPGMFVQHSTAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISK-----DK---ES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91 PsiBlast_CBE 64.8037%-123 - C3 -2YAK DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 64.6239%-131 - C3 -4FG9 KCC1A_HUMAN B:[20-278] -----------------------------------YDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAK--------------------------EIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE---RDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL---DED---S----K---IMISDF--------------V-LSTA-CGTPGYVAPEVLAQKPY------SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA--E--YEFDSP----YWDDISDS-------AKDF----IRHLMEKDPEKRF-----T-----C------EQALQHPW---I--------AG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 64.3637%-116 - C3 -1JKK DAPK1_HUMAN A:[18-273] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 64.2137%-117 - C3 -3DFC DAPK1_HUMAN B:[19-274] -----------------------------------------LGSGKFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 PsiBlast_CBE 64.1737%-121 - C3 -1WVY DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106 PsiBlast_CBE 63.9137%-118 - C3 -3GU6 DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGVFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 63.6637%-117 - C3 -2W4K DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108 PsiBlast_CBE 63.2637%-114 - C3 -3GU4 DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGVFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79 PsiBlast_CBE 63.2137%-117 - C3 -3EHA DAPK1_HUMAN A:[18-273] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEK-SLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107 PsiBlast_CBE 63.0937%-115 - C3 -3GU5 DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGVFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 62.9836%-117 - C3 -3V51 ? A:[20-284] ---------------------------STAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQV-KQKTDKES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 62.8836%-119 - C3 -3I7B ? A:[23-284] ------------------------------IFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQV-KQKTDKES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 62.8536%-116 - C3 -3T3V ? A:[22-284] -----------------------------AIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQV-KQKTDKES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105 PsiBlast_CBE 62.8137%-115 - C3 -3GU7 DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGVFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 62.7436%-119 - C3 -3KU2 ? A:[44-307] ---------------------------T-AIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQV-KQKTDKES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111 PsiBlast_CBE 62.7237%-118 - C3 -3GU8 DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILIGELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92 PsiBlast_CBE 62.4437%-115 - C3 -2W4J DAPK1_HUMAN A:[19-274] -----------------------------------------LGSGQFAVVKKCREKSTGLQYAAKF--IKKRRT-K-----SSRRGVSREDIE---REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTE---EEATEFLKQILNGVYYLHS-LQIAHFDLKPENIM---L---LDR---NVPKPR---IKIIDFGL-AHK-I-DFGNE--FKNI-FGTPEFVAPEIVNYEPL------GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAV--N--YEF--E----DE--YFSN-------TSALAKDFIRRLLVKDPKKRM-----T-----I------QDSLQHPW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 62.3836%-117 - C3 -3N51 ? A:[22-284] -----------------------------AIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQV-KQKTDKES----LL-------REVQLLKQL-D-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSE---VDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L---ESK---SKDA-N---IRIIDFGL-S-T-H-FEASKK-MKDK-IGTAYYIAPEVLHG-TYD------EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYT--FEL--P----QWKKVSES-------AKDL----IRKMLTYVPSMRI-----S-----A------RDALDHEW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------