@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CDK7_HUMAN: (2013-07-19 )
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF

Atome Classification :

(90 SA) .........10...-.....20........30.--.......40........50........60........70........80--.------.------.------.....90.....-...100..-----..-----...110........120.......130.......140...----...-.150.......160...----....170.......180.......190.......200.....-.-----------.210.....-------.----.220.......230.......240.--....---.--.250----..-..-.....260---.-----.......270.......280.......290.......300.......310.......320.......330.......340....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MALDVKSRAKRYEK-LDFLGEGQFATVYKARDK--NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAF--G------H------K------SNISLVFDFMET-DLEVIIKD-----NS-----LVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSP----NRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL-L-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPDMCSL--PDYV---T--FK------SF-PG-IPLHHIF----S-----AAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
113 HHSearch 91.95100%-124 - C1 -1UA2 CDK7_HUMAN A:[13-311] ------------EK-LDFLGEGQFATVYKARDK--NTNQIVAIKKI------------NRTALREIKLLQELSHPNIIGLLDAF--G------H------K------SNISLVFDFMET-DLEVIIKD-----NS-----LVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSP----NRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL-L-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPDMCSL--PDYV---T--FK------SF-PG-IPLHHIF----S-----AAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN-----------------------------------
22 PsiBlast_CBE 79.4899% -90 - C1 -1UA2 CDK7_HUMAN C:[13-311] ------------EK-LDFLGEGQFATVYKARDK--NTNQIVAIKKI------------NRTALREIKLLQELSHPNIIGLLDAF--G------H------K------SNISLVFDFMET-DLEVIIKD-----NS-----LVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSP----NRAY-HQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL-L-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPDMCSL--PDYV---T--FK------SF-PG-IPLHHIF----S-----AAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN-----------------------------------
21 PsiBlast_CBE 78.6899% -87 - C1 -1UA2 CDK7_HUMAN D:[13-311] ------------EK-LDFLGEGQFATVYKARDK--NTNQIVAIKKI------------NRTALREIKLLQELSHPNIIGLLDAF--G------H------K------SNISLVFDFMET-DLEVIIKD-----NS-----LVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSP----NRAY-HQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL-L-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPDMCSL--PDYV---T--FK------SF-PG-IPLHHIF----S-----AAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN-----------------------------------
59 PsiBlast_CBE 78.2744%-119 - C1 -3FZ1 CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFG-----------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
74 PsiBlast_CBE 77.8944%-120 - C1 -2W06 CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF-------------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
82 PsiBlast_CBE 77.8544%-117 - C1 -2VTO CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF------------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
23 PsiBlast_CBE 77.7399% -83 - C1 -1UA2 CDK7_HUMAN B:[13-311] ------------EK-LDFLGEGQFATVYKARDK--NTNQIVAIKKI------------NRTALREIKLLQELSHPNIIGLLDAF--G------H------K------SNISLVFDFMET-DLEVIIKD-----NS-----LVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL----DEN-GVLKLADFGLAKSFGSP----NRAY-HQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL-L-----------RVPFLPGDS-------D----LDQLTRIFETLGTPTEEQWPDMCSL--PDYV---T--FK------SF-PG-IPLHHIF----S-----AAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN-----------------------------------
95 PsiBlast_CBE 77.6444%-119 - C1 -2R64 CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
78 PsiBlast_CBE 77.5344%-119 - C1 -2VTS CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR-----------PSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF------------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
55 PsiBlast_CBE 77.0244%-117 - C1 -3NS9 CDK2_HUMAN A:[3-298] ----------NFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI----------GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
89 PsiBlast_CBE 76.9544%-116 - C1 -2VTA CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR------------STAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
73 PsiBlast_CBE 76.8944%-119 - C1 -2W1H CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
16 PsiBlast_PDB 76.7844%-115 - C1 -1E1V CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
17 PsiBlast_PDB 76.7344%-117 - C1 -1E1X CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
81 PsiBlast_CBE 76.6144%-120 - C1 -2VTP CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF-------------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
85 PsiBlast_CBE 76.3544%-110 - C1 -2VTL CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
58 PsiBlast_CBE 76.3444%-118 - C1 -3LFN CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARA-------------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
54 PsiBlast_CBE 76.2644%-120 - C1 -3S2P CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
79 PsiBlast_CBE 76.2244%-110 - C1 -2VTR CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR-----------PSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
56 PsiBlast_CBE 76.1944%-113 - C1 -3LFS CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR-----------PSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
6 PsiBlast_PDB 76.1944%-112 - C1 -2WIH CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
84 PsiBlast_CBE 76.0544%-112 - C1 -2VTM CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
5 PsiBlast_PDB 76.0144%-113 - C1 -2BKZ CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
68 PsiBlast_CBE 75.9444%-113 - C1 -2XMY CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDT------GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
49 PsiBlast_CBE 75.9344%-115 - C1 -3TIZ CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
9 PsiBlast_PDB 75.9044%-115 - C1 -2WXV CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
88 PsiBlast_CBE 75.8844%-119 - C1 -2VTH CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR------------STAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
50 PsiBlast_CBE 75.8644%-114 - C1 -3TIY CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
4 PsiBlast_PDB 75.8544%-113 - C1 -2BPM CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
3 PsiBlast_PDB 75.8244%-112 - C1 -2C4G CDK2_HUMAN A:[7-302] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------
57 PsiBlast_CBE 75.8044%-115 - C1 -3LFQ CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR------------STAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
8 PsiBlast_PDB 75.7144%-111 - C1 -2WPA CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
27 PsiBlast_CBE 75.7044%-116 - C1 -2WIH CDK2_HUMAN C:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
25 PsiBlast_CBE 75.6444%-116 - C1 -2WPA CDK2_HUMAN C:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
28 PsiBlast_CBE 75.6144%-115 - C1 -2C4G CDK2_HUMAN C:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
87 PsiBlast_CBE 75.5844%-122 - C1 -2VTI CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAF--------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
60 PsiBlast_CBE 75.4944%-115 - C1 -3F5X CDK2_HUMAN C:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
90 PsiBlast_CBE 75.4644%-114 - C1 -2V0D CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRL---------VPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
80 PsiBlast_CBE 75.4144%-120 - C1 -2VTQ CDK2_HUMAN A:[2-298] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIR------------STAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFG-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
30 PsiBlast_CBE 75.3844%-114 - C1 -2BKZ CDK2_HUMAN C:[7-302] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------
29 PsiBlast_CBE 75.2244%-116 - C1 -2BPM CDK2_HUMAN C:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
2 PsiBlast_PDB 75.1544%-110 - C1 -1VYW CDK2_HUMAN A:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
31 PsiBlast_CBE 75.0244%-116 - C1 -1VYW CDK2_HUMAN C:[7-303] ---------ENFQK-VEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNHPNIVKLLDVI--H------T------E------NKLYLVFEFLHQ-DLKKFMDA-----SA-----LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTE-GAIKLADFGLARAFGVP----VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-T-----------RRALFPGDS-------E----IDQLFRIFRTLGTPDEVVWPGVTSM--PDYKP--S--FP------KW-AR-QDFSKVV----P-----PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------
86 PsiBlast_CBE 74.8744%