@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CHK2_HUMAN: (2013-07-19 )
MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL

Atome Classification :

(74 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220..-.....230.......240.......250--........260.......270------.---.......280-..--......290-..-.-------.-.-.-.300.......310..--....----.320.......330.......-340.......350.......360-.......370-..-.-..-----..380-.......390....---...400.......410.......420.......--430----.........440.......450-------------------------..----------------------.......460.......470....-----...480......--------.490.......500.......510.......520.......530.......540.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SKRKFAIGSAREADPALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
25 PsiBlast_CBE 75.97100%-133 - C1 -4BDG ? A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS---GEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
23 PsiBlast_CBE 75.95100%-129 - C1 -4BDI ? A:[8-313] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLG----GEVKLAFERKTCKKVAIKII---SK-------------ALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLAQP----------------------------
7 PsiBlast_PDB 75.24100%-132 - C1 -2YCQ CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
6 PsiBlast_PDB 74.78100%-133 - C1 -2YIT CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SK--------------LNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
13 PsiBlast_PDB 74.63100%-129 - C1 -2WTI CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK------------PALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--E-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
31 PsiBlast_CBE 74.21100%-130 - C1 -2YCF CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
26 PsiBlast_CBE 74.16100%-133 - C1 -4BDF ? A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLG----GEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
21 PsiBlast_CBE 74.06100%-130 - C1 -4BDK ? A:[9-311] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLG----GEVKLAFERKTCKKVAIKII---SK-------------ALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLA------------------------------
22 PsiBlast_CBE 73.98100%-132 - C1 -4BDJ ? A:[9-311] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLG-----EVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--E-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLA------------------------------
29 PsiBlast_CBE 73.94100%-133 - C1 -4BDC ? A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--E-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
4 PsiBlast_PDB 73.91100%-132 - C1 -2YIQ CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLG----GEVKLAFERKTCKKVAIKII---SK----------------VE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
5 PsiBlast_PDB 73.76100%-132 - C1 -2YIR CHK2_HUMAN A:[2-301] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SK--------------LNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALP----------------------------------
12 PsiBlast_PDB 73.68100%-132 - C1 -2WTD CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK------------PALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
14 PsiBlast_PDB 73.47100%-132 - C1 -2WTJ CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK------------PALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--E-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
20 PsiBlast_PDB 73.08100%-135 - C1 -4BDA ? A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--E-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
9 PsiBlast_PDB 73.08100%-131 - C1 -2CN5 CHK2_HUMAN A:[8-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGSGACGEVKLAFERKTCKKVAIKII---SKR--------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENE---------------------------------------
32 PsiBlast_CBE 72.6399%-132 - C1 -2YCR CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLGS---GEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTAKPQ---------------------------------
28 PsiBlast_CBE 72.46100%-140 - C1 -4BDD ? A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TL------EVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
15 PsiBlast_PDB 72.33100%-130 - C1 -2XM9 CHK2_HUMAN A:[9-310] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLGS---GEVKLAFERKTCKKVAIKII---SK------------PALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L-GE-----TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
3 PsiBlast_PDB 72.11100%-133 - C1 -2W0J CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS---GEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENE-TALPQ---------------------------------
11 PsiBlast_PDB 71.96100%-129 - C1 -2WTC CHK2_HUMAN A:[9-310] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK------------PALNVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
8 PsiBlast_PDB 70.59100%-130 - C1 -2YCS CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSK-TLGS---GEVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLCGTPTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H------RTQVSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
10 PsiBlast_PDB 68.75100%-135 - C1 -2CN8 CHK2_HUMAN A:[10-301] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPKALRDEYIMSK-TLGS----EVKLAFERKTCKKVAIKII---SK---------------NVE-------T---EIEILKKL-N-HP--CIIKIKNFF-DA-E-------D-Y-Y-IVLELMEGGELFDKVV--GNKR----LKEATCKLYFYQMLLAVQYLH-ENGIIHRDLKPENVLLSSQEEDC-LIKITDFGHS-KI-L--------TSLMR-TLC--PTYLAPEVL---VSVGTAGYNRAVDCWSLGVILFICLSGYPPFSE--H---------VSLKDQITSGKYNFIPE---------------------------VW----------------------AEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD--------EDMKRKFQDLLSEEN----------------------------------------
41 PsiBlast_CBE 55.2942%-126 - C1 -4FG7 KCC1A_HUMAN A:[16-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDIYDFRD-VLGTGAFSEVILAEDKRTQKLVAIKCI---A----------------SME-------N---EIAVLHKI-K-HP--NIVALDDIY-ES-G-------G-HLY-LIMQLVSGGELFDRIV--EKGF----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLDEDS-KIMISDFGLS-KM-E-DP-----G---------TPGYVAPEVL------AQK--SKAVDCWSIGVIAYILLCGYPPFYD---------ENDAKLFEQILKAEYEFDSP---------------------------YW----------------------DDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI-----------------------------------------------------------------
46 PsiBlast_CBE 54.2742%-126 - C1 -3LIJ ? A:[35-297] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEMYQRVK-KLGS---GEVLLCRDKVTHVERAIKII-----RK-----SSNS----KLL-------E---EVAVLKLL-D-HP--NIMKLYDFFEDK-R-------N-Y-Y-LVMECYKGGELFDEII--HRMK----FNEVDAAVIIKQVLSGVTYLH-KHNIVHRDLKPENLLLESKEKDA-LIKIVDFGLS-AV-F-EN-----QKKMK-ERLGTAYYIAPEVL-------RKKYDEKCDVWSIGVILFILLAGYPPFGG--Q------TDQEILR-KVEKGKYTFDSP---------------------------EW----------------------KNVSEGAKDLIKQMLQFDSQRRIS-----AQQALEHPWIKE---------------------------------------------------------------
74 PsiBlast_CBE 53.0738%-121 - C1 -3MFS CSKP_HUMAN A:[22-294] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEDVYELCE-VIGKGAFSVVRRCINRETGQQFAVKIV---DVAKFT------SSPGLSTE-------DLKREASICHML-K-HP--HIVELLETY-SS-D-------G-MLY-MVFEFMDGADLCFEIV--KRADAGFVYSEAVASHYMRQILEALRYCH-DNNIIHRDVKPENVLLASKENSA-PVKLGDFGVA-IQ-L-GE-----SGLVAGGRVGTPHFMAPEV------VKREPYGKPVDVWGCGVILFILLSGCLPF----Y------GTKERLFEGIIKGKYKMNPR---------------------------QW----------------------SHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKE--------RD-----------------------------------------------------
73 PsiBlast_CBE 52.6938%-120 - C1 -3MFU CSKP_HUMAN A:[22-294] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEDVYELCE-VIGKGAFSVVRRCINRETGQQFAVKIV---DVAKFT------SSPGLSTE-------DLKREASICHML-K-HP--HIVELLETY-SS-D-------G-MLY-MVFEFMDGADLCFEIV--KRADAGFVYSEAVASHYMRQILEALRYCH-DNNIIHRDVKPENVLLASKENSA-PVKLGDFGVA-IQ-L-GE-----SGLVAGGRVGTPHFMAPEV------VKREPYGKPVDVWGCGVILFILLSGCLPF----Y------GTKERLFEGIIKGKYKMNPR---------------------------QW----------------------SHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKE--------RD-----------------------------------------------------
70 PsiBlast_CBE 51.8838%-116 - C1 -2WEL KCC2D_HUMAN A:[1-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMTDEYQLFE-ELGKGAFSVVRRCMKIPTGQEYAAKII---NTKKL---SARDHQ---KLE-------R---EARICRLL-K-HP--NIVRLHDSI-SE-E-------G-FHY-LVFDLVTGGELFEDIV--AREY----YSEADASHCIQQILESVNHCH-LNGIVHRDLKPENLLLASKSKGA-AVKLADFGLAIEV-Q-GD-----QQAWF-GFAGTPGYLSPEVL---RK---DPYGKPVDMWACGVILYILLVGYPPFWD---------EDQHRLYQQIKAGAYDFPSP---------------------------EW----------------------DTVTPEAKDLINKMLTINPAKRIT-----ASEALKHPWI-----------------------------------------------------------------
39 PsiBlast_CBE 51.7342%-131 - C1 -4FG8 KCC1A_HUMAN B:[16-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDIYDFRD-VLGTGAFSEVILAEDKRTQKLVAIKCI---AK-------------------------N---EIAVLHKI-K-HP--NIVALDDIY-ES-G-------G-HLY-LIMQLVSGGELFDRIV--EKGF----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLDEDS-KIMISDFG---------------GSVLS-TACGTPGYVAPEVL------AQKPYSKAVDCWSIGVIAYILLCGYPPFYD---------ENDAKLFEQILKAEYEFDSP---------------------------YW----------------------DDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI-----------------------------------------------------------------
53 PsiBlast_CBE 51.3541%-126 - C1 -3HX4 ? A:[50-310] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRYKGQR-VLGKGSFGEVILCKDKITGQECAVKVI---SK-------DKES-----LL-------R---EVQLLKQL-D-HP--NIMKLYEFF-ED-K-------G-YFY-LVGEVYTGGELFDEII--SRKR----FSEVDAARIIRQVLSGITYMH-KNKIVHRDLKPENLLLESKSKDA-NIRIIDFGLS-TH-F-EA-----SKKMK-DKIGTAYYIAPEVL-----HGT--YDEKCDVWSTGVILYILLSGCPPFNG--A------NEYDILK-KVEKGKYTFELP---------------------------QW----------------------KKVSESAKDLIRKMLTYVPSMRIS-----ARDALDHEWIQ----------------------------------------------------------------
45 PsiBlast_CBE 51.3042%-130 - C1 -2JC6 KCC1D_HUMAN A:[28-280] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-TLGTGAFSEVVLAEEKATGKLFAVKCI---PKKA--------S----SIE-------N---EIAVLRKI-K-HE--NIVALEDIY-ES-P-------N-HLY-LVMQLVSGGELFDRIV--EKGF----YTEKDASTLIRQVLDAVYYLH-RMGIVHRDLKPENLLYYSQDEES-KIMIS-----------------------------PGYVAPEVL------AQKPYSKAVDCWSIGVIAYILLCGYPPFYD--E------NDS-KLFEQILKAEYEFDSP---------------------------YW----------------------DDISDSAKDFIRNLMEKDPNKRYT-----CEQAARHPWI-----------------------------------------------------------------
83 PsiBlast_CBE 51.2836%-114 - C1 -2V7O KCC2G_HUMAN A:[31-291] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDYQLFE-ELGKG-FSVVRRCVKKTPTQEYAAKII---NTKKL---SARDHQ---KLE-------R---EARICRLL-K-HP--NIVRLHDSI-SE-E-------G-FHY-LVFDLVTGGELFEDIV--AREY----YSEADASHCIHQILESVNHIH-QHDIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEV-Q-GE-----QQAWF-GFAGTPGYLSPEVL---RK---DPYGKPVDIWACGVILYILLVGYPPFWD---------EDQHKLYQQIKAGAYDFPSP---------------------------EW----------------------DTVTPEAKNLINQMLTINPAKRIT-----ADQALKHPWV-----------------------------------------------------------------
69 PsiBlast_CBE 50.7939%-123 - C1 -3Q5I ? A:[38-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFKVR-KLGS--YGEVLLCKEKNGHSEKAIKVI---KK------------------KFHEEIYN---EISLLKSL-D-HP--NIIKLFDVFEDK-K-------Y-F-Y-LVTEFYEGGELFEQII--NRHK----FDECDAANIMKQILSGICYLH-KHNIVHRDIKPENILLENKNSLL-NIKIVDFGLS-SF-F-SK-----DYKLR-DRLGTAYYIAPEVL-------KKKYNEKCDVWSCGVIMYILLCGYPPFGG--Q------NDQDIIK-KVEKGKYYFDFN---------------------------DW----------------------KNISDEAKELIKLMLTYDYNKRCT-----AEEALNSRWIK----------------------------------------------------------------
40 PsiBlast_CBE 50.2642%-133 - C1 -4FG8 KCC1A_HUMAN A:[16-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDIYDFRD-VLGTGAFSEVILAEDKRTQKLVAIKCI---AKE------------------------N---EIAVLHKI-K-HP--NIVALDDIY-ES-G-------G-HLY-LIMQLVSGGELFDRIV--EKGF----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLDEDS-KIMISDF--------------------------TPGYVAPEVL------AQKPYSKAVDCWSIGVIAYILLCGYPPFYD---------ENDAKLFEQILKAEYEFDSP---------------------------YW----------------------DDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI-----------------------------------------------------------------
42 PsiBlast_CBE 50.1444%-118 - C1 -2JAM KCC1G_HUMAN B:[7-265] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRKTFIFME-VLGSGAFSEVFLVKQRLTGKLFALKCI---KK-----------S---SLE-------N---EIAVLKKI-K-HE--NIVTLEDIY-ES-TT------H-Y-Y-LVMQLVSGGELFDRIL--ERGV----YTEKDASLVIQQVLSAVKYLH-ENGIVHRDLKPENLLYLTPEENS-KIMITDFGLS-K--M-EQ-----NGIMS-TACGTPGYVAPEVL------AQKPYSKAVDCWSIGVITYILLCGYPPFYE---------ETESKLFEKIKEGYYEFESP---------------------------FW----------------------DDISESAKDFICHLLEKDPNERYT-----CEKALSHPWI-----------------------------------------------------------------
43 PsiBlast_CBE 50.1244%-120 - C1 -2JAM KCC1G_HUMAN A:[7-265] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRKTFIFME-VLGSGAFSEVFLVKQRLTGKLFALKCI---KK-----------S---SLE-------N---EIAVLKKI-K-HE--NIVTLEDIY-ES-TT------H-Y-Y-LVMQLVSGGELFDRIL--ERGV----YTEKDASLVIQQVLSAVKYLH-ENGIVHRDLKPENLLYLTPEENS-KIMITDFGLS-K--M-EQ-----NGIMS-TACGTPGYVAPEVL------AQKPYSKAVDCWSIGVITYILLCGYPPFYE---------ETESKLFEKIKEGYYEFESP---------------------------FW----------------------DDISESAKDFICHLLEKDPNERYT-----CEKALSHPWI-----------------------------------------------------------------