@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ERBB2_HUMAN: (2013-07-20 )
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV

Atome Classification :

(66 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720..---.....730.......740........750.......760.......770.......780.......790-.-......800.......810...---....820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.....---..980.......990..-......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTS-T-VQLVTQLMPYGCLLDHVRENRG---RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS---RMARDPQRFVVIQ-NED-LGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
22 PsiBlast_CBE 70.8599%-108 - C3 -3PP0 B:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETELRKVK---VLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTS-T-VQLVTQLMPYGCLLDHVRENRG---RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA--GKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS---RMARDPQRFVVIQ-NE-------PLDSTFYRSLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 70.5999%-111 - C3 -3PP0 ERBB2_HUMAN A:[5-292] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETELRKVK---VLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTS-T-VQLVTQLMPYGCLLDHVRENRG---RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA--GKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS---RMARDPQRFVVIQ-NED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 70.1477%-106 - C3 -3W32 A:[9-325] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDMDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 69.8977%-104 - C3 -3IKA EGFR_HUMAN A:[5-329] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MH---------------EEDMDDVVDADEYLIPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62 PsiBlast_CBE 69.7377%-115 - C3 -2GS7 B:[9-324] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA---KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQG--------------------------DVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 69.6277%-112 - C3 -3W2O A:[8-326] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLP----------------MDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 69.5177%-114 - C3 -3W2S A:[9-327] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 69.2278%-113 - C3 -1M17 A:[7-330] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL------------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 69.1577%-115 - C3 -3VJN A:[9-330] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLSS---GTVYKGLWIP-EGEKVKIPVAIKEL-EATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD----------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 69.1377%-116 - C3 -3W33 A:[9-326] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELR-----KANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMD----DDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 69.0877%-113 - C3 -2GS7 EGFR_HUMAN A:[11-320] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYH----KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQG--------------------------DVVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 69.0278%-126 - C3 -2RGP A:[1-315] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-----VKIPVAIKELR-----KANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK--------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-M--------NFYRALMD------VVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 68.9877%-110 - C3 -3W2P A:[8-327] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPS--------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 68.9677%-105 - C3 -2GS6 A:[4-327] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL---TSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPS-------------EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 68.8277%-110 - C3 -3W2Q A:[8-326] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSP--------------MDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64 PsiBlast_CBE 68.7377%-116 - C3 -4JRV ? A:[3-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL---TSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD----------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 68.6377%-112 - C3 -3GT8 EGFR_HUMAN C:[7-315] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL-------------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 68.6278%-122 - C3 -1XKK A:[32-348] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-----VKIPVAIKELRE----KANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK--------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-M-------SNFYRALMDE-----VVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 68.4274%-110 - C3 -3BCE C:[2-289] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAPNQAQLRILKETELKRVK---VLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSP-T-IQLVTQLMPHGCLLEYVHEHKD---NIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLE-DEKEYNADG-KMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS---RMARDPQRYLVIQ-GD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 68.3277%-111 - C3 -3UG2 A:[9-330] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLSS---GTVYKGLWIP-EGEKVKIPVAIKE-----SPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL---------------EDMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 68.2977%-104 - C3 -2ITO A:[1-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLSSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEE---------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL------------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 68.2777%-116 - C3 -4JR3 ? A:[3-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD----------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67 PsiBlast_CBE 68.2577%-113 - C3 -4JQ7 ? A:[3-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD----------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 68.1178%-106 - C3 -4I23 A:[2-325] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEAPNQALLRILKETEFKKIK---VLGS---GTVYKGLWIP-EGEKVKIPVAIKEL--ATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLP---------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66 PsiBlast_CBE 68.0777%-115 - C3 -4JQ8 ? A:[3-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD----------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81 PsiBlast_CBE 68.0478%-111 - C3 -2R4B ERBB4_HUMAN A:[16-313] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAPNQAQLRILKETELKRVK---VLGSGAFGTVYKGIWVP-EGETVKIPVAIKILN------ANVEFMDEALIMASMDHPHLVRLLGVCLSP-T-IQLVTQLMPHGCLLEYVHEHKD---NIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS---RMARDPQRYLVIQ-GDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60 PsiBlast_CBE 68.0277%-108 - C3 -2ITT A:[2-324] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEE---------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL------------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31 PsiBlast_CBE 67.9378%-107 - C3 -3VJO A:[8-330] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGS--FGTVYKGLWIP-EGEKVKIPVAIK---EATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDE---------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 67.9099%-108 - C3 -3RCD ERBB2_HUMAN C:[9-321] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETELRKVK---VLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLR----PKANKEILDEAYVMAGVGSPYVSRLLGICLTS-T-VQLVTQLMPYGCLLDHVRENRG---RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGL-----------------VPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS---RMARDPQRFVVIQ-N---------LDSTFYRSLLEDD---DLVDAEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 67.7577%-106 - C3 -4I22 A:[7-321] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELR-----KANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLL-------------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDMDDVVDAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 67.7378%-120 - C3 -3BEL A:[1-314] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-----VKIPVAIKEL------KANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK--------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER----------NFYRALM-------VVDADE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46 PsiBlast_CBE 67.7377%-105 - C3 -4I24 EGFR_HUMAN A:[7-321] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-------ANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL-------------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDMDDVVDAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 67.7278%-114 - C3 -4HJO A:[18-299] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-----VKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 67.7277%-105 - C3 -2ITX A:[2-324] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKL----EKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL------------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87 PsiBlast_CBE 67.7180%-118 - C3 -3LZB EGFR_HUMAN A:[8-287] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGL----------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 PsiBlast_CBE 67.7177%-106 - C3 -4G5J A:[4-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGS----TVYKGLWIP-EGEKVKIPVAIKE----------KEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMDEEDMDDVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 67.6677%-111 - C3 -4G5P EGFR_HUMAN A:[4-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLIMQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-----------------------DVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 67.6077%-117 - C3 -3POZ A:[6-322] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-----VKIPVAIKEL-------ANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK-------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPSPTDSNFYRALMD------VVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 67.5977%-108 - C3 -2ITU A:[1-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAE----------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHLPS----------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 67.5877%-104 - C3 -2J6M A:[2-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD-------------------DEEDMDDVVDADEYLIPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 67.2077%-109 - C3 -2ITN A:[1-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLSSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEE---------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL-----------LMDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 67.1377%-110 - C3 -2ITV A:[1-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEE---------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL------------MDEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 67.1278%-112 - C3 -2R4B B:[16-313] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAPNQAQLRILKETELKRVK---VLGSGAFGTVYKGIWVP-EGETVKIPVAIKIL-------ANVEFMDEALIMASMDHPHLVRLLGVCLSP-T-IQLVTQLMPHGCLLEYVHEHKD---NIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS---RMARDPQRYLVIQ-GDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 67.1277%-107 - C3 -2ITP A:[2-323] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLSSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGD------------------MDEEDMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86 PsiBlast_CBE 67.1080%-115 - C3 -3LZB EGFR_HUMAN B:[8-287] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGL----------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 66.9899%-109 - C3 -3RCD ERBB2_HUMAN A:[9-321] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETELRKVK---VLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLR----PKANKEILDEAYVMAGVGSPYVSRLLGICLTS-T-VQLVTQLMPYGCLLDHVRENRG---RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGL-----------------VPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS---RMARDPQRFVVIQ-N---------LDSTFYRSLLEDD---DLVDAEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 PsiBlast_CBE 66.8677%-108 - C3 -2ITY A:[2-324] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETEFKKIK---VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS-T-VQLITQLMPFGCLLDYVREHKD---NIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAE----------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFS---KMARDPQRYLVIQGDER-MHL-------------DEEDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 66.7577%-108 - C3 -2ITQ A:[2-323] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E