@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : new_query: (2013-07-20 )
MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV

Atome Classification :

(71 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.....---..720.-----......730......-.-740.......750.......760.......770.......780.....---..-790.........800.......810-.---...--...820.......830.......840.......850...----....860.......870.......880---.......890.......900.......910.......920---........930......------.940.......950.......960.......970..--------.....980.......990.......1000......1010-.........1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300.....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P-EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLARLLEGDEKEYNADGGKM---PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDE----EDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
11 PsiBlast_PDB 74.28100%-126 - C5 -2R4B ERBB4_HUMAN A:[16-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAPNQAQLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P-EGETVKIPVAIKILN------ANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLARLLEGDEKEYNADGGKM---PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQGDD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 74.18100%-121 - C5 -3BCE C:[2-289] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAPNQAQLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P-EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLARLLE-DEKEYNADG-KM---PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQGD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 73.52100%-125 - C5 -2R4B B:[16-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAPNQAQLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P-EGETVKIPVAIKIL-------ANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLARLLEGDEKEYNADGGKM---PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQGDD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 73.4677%-118 - C5 -3W2O A:[7-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLP--------------------MDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 73.33100%-129 - C5 -3BBT ERBB4_HUMAN B:[7-297] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P-EGETVKIPVAIKILNE--GPKANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLARLL-----------------PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQ-DDRMKLPSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 72.6377%-110 - C5 -3W32 A:[9-325] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDE----EDMDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 72.5777%-117 - C5 -3W2P A:[7-327] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPS------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 72.03100%-130 - C5 -3BBT D:[8-287] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLRILKETE---LKRVKV-----LGSGAFGTVYKGIWV-P---ETVKIPVAIKILNE---PKANVEFMDEALIMASMDHPHLVRLLGVC---LS-P--TIQLVTQLMPHGCLLEYVHEHK-D---NIG--SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN----HVKITDFGLAR-------------------PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPY----DGIPTREIPDLLEKGER------LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF--------SRMARDPQRYLVIQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60 PsiBlast_CBE 71.8277%-122 - C5 -3VJN A:[9-330] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LSS---GTVYKGLWI-P-EGEKVKIPVAIKEL-EATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-------------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42 PsiBlast_CBE 71.8277%-121 - C5 -3POZ A:[6-322] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKEL-------ANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEK-------KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMD----------VVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 71.7777%-121 - C5 -3W33 A:[9-326] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELR-----KANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLL------------KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMD--------DDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 71.7577%-116 - C5 -3W2Q A:[7-326] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSP------------------MDDVVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
123 HHSearch 71.7277%-121 - C5 -3POZ A:[6-322] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKEL-------ANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEK-------KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMD----------VVDADEYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 71.7077%-119 - C5 -4JR3 ? A:[3-326] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-------------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 71.6077%-126 - C5 -2RGP A:[1-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKELR-----KANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEK--------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERM--------NFYRALMD----------VVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 71.5677%-119 - C5 -3W2S A:[9-327] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLL------------KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 PsiBlast_CBE 71.5377%-114 - C5 -4I23 A:[2-325] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEAPNQALLRILKETE---FKKIKV-----LGS---GTVYKGLWI-P-EGEKVKIPVAIKEL--ATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLP-------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 71.4977%-108 - C5 -3IKA EGFR_HUMAN A:[5-329] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMH---------------E----EDMDDVVDADEYLIPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 71.3677%-118 - C5 -2ITN A:[1-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LSSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEE---------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL-----------LMDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 71.1577%-117 - C5 -1M17 A:[7-330] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL------------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 71.1177%-111 - C5 -2GS6 A:[4-327] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKEL---TSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPS-----------------EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 71.0477%-118 - C5 -4JQ8 ? A:[3-326] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-------------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 71.0477%-121 - C5 -4JRV ? A:[3-326] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKEL---TSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-------------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 71.0077%-115 - C5 -2ITU A:[1-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAE----------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPS----------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 70.9677%-124 - C5 -1XKK A:[32-348] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKELRE----KANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEK--------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERM-------SNFYRALMDE---------VVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67 PsiBlast_CBE 70.8577%-117 - C5 -2ITV A:[1-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAEE---------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL------------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 70.8577%-116 - C5 -4JQ7 ? A:[3-326] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-------------------------DMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 PsiBlast_CBE 70.7677%-111 - C5 -3VJO A:[8-330] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGS--FGTVYKGLWI-P-EGEKVKIPVAIK---EATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDE------------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 70.7577%-126 - C5 -3BEL A:[1-314] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKEL------KANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEK--------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDER---------NFYRALM-----------VVDADE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64 PsiBlast_CBE 70.7077%-119 - C5 -2GS7 B:[9-324] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHA---KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQG-----------------------------DVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 70.6477%-118 - C5 -2ITT A:[2-324] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGRAKLLGAEE---------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL------------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 70.5977%-118 - C5 -2GS7 EGFR_HUMAN A:[11-320] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYH----KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQG-----------------------------DVVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 70.5877%-118 - C5 -3UG2 A:[9-330] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LSS---GTVYKGLWI-P-EGEKVKIPVAIKE-----SPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL-------------------EDMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 70.5077%-116 - C5 -3GT8 EGFR_HUMAN C:[7-315] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLL-------------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDE----EDM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 70.4777%-119 - C5 -4G5P EGFR_HUMAN A:[4-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDER--------------------------DVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 PsiBlast_CBE 70.4277%-109 - C5 -2J6M A:[2-325] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD------------------DE----EDMDDVVDADEYLIPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46 PsiBlast_CBE 70.2177%-111 - C5 -2ITX A:[2-324] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKL----EKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL------------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 70.1577%-113 - C5 -2ITQ A:[2-323] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LSSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQG--------------------------DMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 70.0877%-114 - C5 -2ITO A:[1-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LSSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEE---------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL------------MDE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45 PsiBlast_CBE 70.0777%-118 - C5 -2ITY A:[2-324] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAE----------V---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHL-------------DE----EDMDDVVDADEYLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62 PsiBlast_CBE 69.6577%-112 - C5 -3UG1 A:[9-330] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LSS---GTVYKGLWI-P-EGEKVKIPVAIKE-----SPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLIMQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD------------------DE----EDMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 69.6477%-113 - C5 -2ITP A:[2-323] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPNQALLRILKETE---FKKIKV-----LSSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD-----------------MDE----EDMDDVVDADEYLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78 PsiBlast_CBE 69.5174%-112 - C5 -3PP0 ERBB2_HUMAN A:[5-292] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETE---LRKVKV-----LGSGAFGTVYKGIWI-P-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGIC---LT-S--TVQLVTQLMPYGCLLDHVRENR-G---RLG--SQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPN----HVKITDFGLARLLDIDETEYHA--GKV---PIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPY----DGIPAREIPDLLEKGER------LPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF--------SRMARDPQRFVVIQNED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 69.4177%-119 - C5 -4HJO A:[18-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-----VKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 69.3677%-107 - C5 -4G5J A:[4-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEAPNQALLRILKETE---FKKIKV-----LGS----TVYKGLWI-P-EGEKVKIPVAIKE----------KEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGLAKLLGAEEKEYHAEGGKV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDE----EDMDDVVDADEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 69.2574%-111 - C5 -3PP0 B:[5-308] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNQALLRILKETE---LRKVKV-----LGSGAFGTVYKGIWI-P-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGIC---LT-S--TVQLVTQLMPYGCLLDHVRENR-G---RLG--SQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPN----HVKITDFGLARLLDIDETEYHA--GKV---PIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPY----DGIPAREIPDLLEKGER------LPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF--------SRMARDPQRFVVIQNE-------PLDSTFYRSLL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88 PsiBlast_CBE 69.1779%-122 - C5 -3LZB EGFR_HUMAN B:[8-288] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLRILKETE---FKKIKV-----LGSGAFGTVYKGLWI-P-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC---LT-S--TVQLITQLMPFGCLLDYVREHK-D---NIG--SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQ----HVKITDFGL----------------KV---PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPY----DGIPASEISSILEKGER------LPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEF--------SKMARDPQRYLVIQG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------