@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : FGFR1_HUMAN: (2015-06-17 )
MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR

Atome Classification :

(82 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......-470.......480........490.......500.......510.......520....-...530.......540.......550.-......560.......570.......580.......590.......600.......610.......620.......630.......640.......650........660.......670.......680.......690.......700.....-..710........720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDP-RWELPRDRLVLG-KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
5 PsiBlast_PDB 95.0999%-123 - C3 -1FGI FGFR1_HUMAN A:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRP------------PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
7 PsiBlast_PDB 95.0199%-126 - C3 -2FGI FGFR1_HUMAN A:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPL-----GQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP--------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-DIHH-IDYYKKT-NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
20 PsiBlast_PDB 94.7599%-122 - C3 -3C4F FGFR1_HUMAN A:[1-302] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
9 PsiBlast_PDB 94.5099%-116 - C3 -3JS2 FGFR1_HUMAN A:[16-317] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGL-------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
21 PsiBlast_CBE 94.2399%-124 - C3 -3GQL C:[15-318] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-------------EQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR-----------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEY--------------------------------------------------------
12 PsiBlast_PDB 94.2299%-128 - C3 -4F64 FGFR1_HUMAN A:[8-306] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPL-----GQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
26 PsiBlast_CBE 94.1499%-127 - C3 -1FGI B:[6-306] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
37 PsiBlast_CBE 93.7599%-121 - C3 -3RHX FGFR1_HUMAN A:[5-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ----------------------------------------------------------
13 PsiBlast_PDB 93.6899%-121 - C3 -4F65 FGFR1_HUMAN A:[8-309] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDK--PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-----------PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF-----------YYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
11 PsiBlast_PDB 93.4799%-126 - C3 -4F63 FGFR1_HUMAN A:[8-306] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPL-----GQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
1 PsiBlast_PDB 93.4299%-112 - C3 -3GQL FGFR1_HUMAN A:[15-326] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-------------EQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR-------------NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLD------------------------------------------------
6 PsiBlast_PDB 93.2299%-124 - C3 -1AGW FGFR1_HUMAN A:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPL-----GQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRP------------PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
22 PsiBlast_CBE 93.1799%-118 - C3 -3GQL FGFR1_HUMAN B:[15-317] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-----------PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR-----------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
27 PsiBlast_CBE 93.1699%-125 - C3 -1AGW B:[6-306] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
38 PsiBlast_CBE 93.1199%-119 - C3 -3C4F B:[1-302] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
29 PsiBlast_CBE 93.0299%-114 - C3 -3JS2 B:[11-314] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVSEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-------------EQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS------------------------------------------------------------
33 PsiBlast_CBE 92.7599%-121 - C3 -4F65 B:[4-307] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLD---PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRP---------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF-------H-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSN-----------------------------------------------------------
34 PsiBlast_CBE 92.6099%-123 - C3 -4F64 B:[5-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
2 PsiBlast_PDB 92.4697%-121 - C3 -3GQI A:[16-322] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS----------------------------------------------------
23 PsiBlast_CBE 92.0299%-122 - C3 -3TT0 B:[52-356] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVSEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSN-----------------------------------------------------------
35 PsiBlast_CBE 91.8699%-123 - C3 -4F63 B:[5-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGA-GQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
3 PsiBlast_PDB 91.8699%-113 - C3 -3TT0 FGFR1_HUMAN A:[54-358] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
129 HHSearch 91.6398%-113 - C3 -3TT0 FGFR1_HUMAN A:[54-358] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE---------------------------------------------------------
25 PsiBlast_CBE 90.9399%-121 - C3 -2FGI B:[6-306] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
19 PsiBlast_PDB 90.6699%-120 - C3 -3RHX B:[2-302] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-RWELPRDRLVLG-KPLGEGAFGQVVLAEAIGL----PNRVTKVAVKMLKSDATEKDLS-DLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR----------------QLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-------DYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE-ELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT-------------------------------------------------------------
46 PsiBlast_CBE 89.5387%-117 - C3 -3B2T B:[1-307] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMLAGVSEYELPEDP-KWEFPRDKLTLG-KPL----FGQVVMAEAVGID--KPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP--------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLTARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
127 HHSearch 89.2286%-117 - C3 -2PVF A:[23-321] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKP---VTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPPGMEYSY--------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT------------------------------------------------------------
57 PsiBlast_CBE 89.1486%-121 - C3 -2PZP FGFR2_HUMAN A:[24-322] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPL------QVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEEDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRP-------------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------------------
76 PsiBlast_CBE 89.0686%-120 - C3 -2PY3 FGFR2_HUMAN A:[24-322] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPL----FGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVGYASKGNLREYLRARRP-------------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------------------
58 PsiBlast_CBE 88.9986%-123 - C3 -4J95 ? D:[23-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR----------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI------------GRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
56 PsiBlast_CBE 88.7886%-119 - C3 -2PZP B:[24-322] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPL------QVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEEDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPPG-----------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------------------
67 PsiBlast_CBE 88.7286%-119 - C3 -4J99 ? D:[21-320] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR----------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKT---GRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
61 PsiBlast_CBE 88.7086%-119 - C3 -4J95 FGFR2_HUMAN A:[23-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRP---------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-----YYKNTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
48 PsiBlast_CBE 88.3686%-121 - C3 -2PZR B:[23-322] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPL------QVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP------------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMRIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------------------
47 PsiBlast_CBE 88.3287%-114 - C3 -3B2T FGFR2_HUMAN A:[7-311] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYELPEDP-KWEFPRDKLTLG-KPLGEGCFGQVVMAEAVGID---PKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP--------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLTARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNQE---------------------------------------------------------
69 PsiBlast_CBE 88.2486%-117 - C3 -4J99 B:[23-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPPGMEYSYD-------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKTTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
68 PsiBlast_CBE 88.0986%-120 - C3 -4J99 ? C:[23-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPPGMEYSYD-------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKTTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
42 PsiBlast_CBE 88.0487%-120 - C3 -3RI1 ? A:[13-310] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP-------------EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT------------------------------------------------------------
52 PsiBlast_CBE 87.9686%-118 - C3 -4J97 ? D:[22-320] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELPEDP-KWEFPRDKLTLG-KPL-----GQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP---------RVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
65 PsiBlast_CBE 87.9186%-121 - C3 -2PZ5 B:[24-322] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPL------QVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIITLLGACTQ-DGPLYVIVEYASKGNLREYLRARRPP-------------EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------------------
74 PsiBlast_CBE 87.7486%-114 - C3 -2PWL FGFR2_HUMAN A:[23-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPEDP-KWEFPRDKLTLG-KPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMIGKHKNIIHLLGACTQ-DGPLYVIVEYASKGNLREYLRARRP--------------EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINN-IDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVE-ELF-KLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT-------------------------------------------------------------
63 PsiBlast_CBE 87.6286%-123 - C3 -2Q0B FGFR2_HUMAN A:[24-321] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEDP-KWEFPRDKLTLG-KPL-----GQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLS-DLVSEMEMMKMI<