@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : GRK5_HUMAN: (2013-07-20 )
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQVGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS

Atome Classification :

(54 SA) .........10........20....---....30........40........50.....--...60........70-----........80........90-.--.......100.......110.......120.......130.......-140.......150.......160.......170.......-180.......190.......200...---..-----..----210.......220.......230.....-..240-..---......250.......260.......270.......--280.......290.......300...-....310......---.320.......330...-.-...-340.....----...350......-.360.......370.......380.......390.......400...----....410.......420.......430.......440........450.......460.......470.......480..--.....490.......500.......510.......520.......530......-.540.......550.......560.......570.......580.......590
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MELENIVANTVLLKAREGGGGKRKG---KSKKWKEILKFPHISQCEDLRRTIDRDYCSL--CDKQPIGRLLFRQFC-----ETRPGLECYIQFLDSVAEYE-V--TPDEKLGEKGKEIMTKYLTPKSPVFIAQVGQDLVSQTEEKLLQKPCK-ELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKRLEKKRIKKRKGESMALNEKQI-LEK-V-NS---QFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG--NPGFEEERALFYAAEILCGLEDLHRE-NTVYRDLKPENIL---LDDYGHIRISDLGLAVK-I-PEG-DL-IRGRV----GTVGYMAPEVLN-NQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE----EVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAE-VKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFS--TVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-RNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
109 Fugue 91.7269%-101 - C1 -2ACX GRK6_HUMAN A:[14-532] --------------------KARKG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERNPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRNLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDP-------------------QAIYCEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGS-----------------------------------------------------------
10 PsiBlast_CBE 91.3371%-100 - C1 -2ACX GRK6_HUMAN B:[14-535] -------------KAR-------KG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERNPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRNLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHM----AGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQQ---KIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIY--------------------EPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPP--------------------------------------------------------
15 PsiBlast_CBE 84.7747% -94 - C1 -3C4W RK_BOVIN B:[9-533] -----VVANSAFIAAR-GSFDASSGPASRDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG------D-GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN----------TVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
13 PsiBlast_CBE 84.4047% -97 - C1 -3C50 RK_BOVIN B:[30-533] -------------------------S--RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG----AGD-GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYA--------FS--TVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
14 PsiBlast_CBE 84.2947%-102 - C1 -3C4X RK_BOVIN B:[31-533] ----------------------------RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARA-------------FQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPDSRT----------------------EKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
110 Fugue 83.2148% -98 - C1 -3C4Z RK_BOVIN A:[31-533] ----------------------------RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG--------GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAGQTK-TKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN-------G--AFSGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
4 PsiBlast_PDB 83.0347% -95 - C1 -3C4X RK_BOVIN A:[30-533] -------------------------S--RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG----AGD-GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPD--------IQDVGAFS--TVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
8 PsiBlast_PDB 82.5447% -98 - C1 -3C4W RK_BOVIN A:[31-533] ----------------------------RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG----AGD-GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPD---------QDVGAFS--TVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
7 PsiBlast_PDB 81.3847% -95 - C1 -3C51 RK_BOVIN A:[31-533] ----------------------------RDRKYLARLKLPPLSKCEALRESLDLGFEGM--CLEQPIGKRLFQQFL-----RTHEQHGPALQLWKDIEDYD-T--ADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAG--------GLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---KA-----TG----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LAK-V-HS---RFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQR-NIIYRDLKPENVL---LDDDGNVRISDLGLAVE-L-KAG-QTKTKGYA----GTPGFMAPELLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQA----VTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDG-LRTHPLFRDISWRQLEAGMLTPPFVPDSR-------------S--TVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP--------------------------------------------------------------
25 PsiBlast_CBE 71.5237% -90 - C1 -3PVU ARBK1_BOVIN A:[30-531] -------------------------------K-KILLPEPSIRSVMQ-KYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKP----LVEFYEEIKKYE-KLETEEERLV-CSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---AD-----TG----KMYAMKCLDKKRIKMKQGETLALNERIM-LSL-V-STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG--V--FSEADMRFYAAEIILGLEHMHNR-FVVYRDLKPANIL---LDEHGHVRISDLGLACD-F-SKK-K--PHASV----GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKH-EIDRMTLTMA----VELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQE-VKESPFFRSLDWQMVFLQKYPPPLIPPRG------------------------DSDQELYRNFPL-TISERWQQEVAET-VFDTINA-----------------------------------------------------------------
24 PsiBlast_CBE 70.8237% -86 - C1 -3PVW ARBK1_BOVIN A:[29-531] ------------------------------SK-KILLPEPSIRSVMQ-KYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKP----LVEFYEEIKKYE-KLETEEERLV-CSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---AD-----TG----KMYAMKCLDKKRIKMKQGETLALNERIM-LSL-V-STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG--V--FSEADMRFYAAEIILGLEHMHNR-FVVYRDLKPANIL---LDEHGHVRISDLGLACD-F-SKK-K--PHASV----GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKH-EIDRMTLTMA----VELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQE-VKESPFFRSLDWQMVFLQKYPPPLIPPRG---------------------KLLDSDQELYRNFPL-TISERWQQEVAET-VFDTINA-----------------------------------------------------------------
21 PsiBlast_CBE 70.5337% -85 - C1 -3KRW ARBK1_HUMAN A:[29-530] -------------------------------K-KILLPEPSIRSVMQ-KYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARP----LVEFYEEIKKYEKL--ETEEERVARSREIFDSYIMKELLA--HPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---AD-----TG----KMYAMKCLDKKRIKMKQGETLALNERIM-LSL-V-STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG--V--FSEADMRFYAAEIILGLEHMHNR-FVVYRDLKPANIL---LDEHGHVRISDLGLACD-F-SKK-K--PHASV----GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK-HEIDRMTLTMA----VELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQE-VKESPFFRSLDWQMVFLQKYPPPLIPPR---------------EEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFDTINA-----------------------------------------------------------------
20 PsiBlast_CBE 69.8137% -83 - C1 -3KRX ARBK1_HUMAN A:[29-530] -------------------------------K-KILLPEPSIRSVMQ-KYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARP----LVEFYEEIKKYEKL--ETEEERVARSREIFDSYIMKELLA--HPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---AD-----TG----KMYAMKCLDKKRIKMKQGETLALNERIM-LSL-V-STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG--V--FSEADMRFYAAEIILGLEHMHNR-FVVYRDLKPANIL---LDEHGHVRISDLGLACD-F-SKK-K--PHASV----GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK-HEIDRMTLTMA----VELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQE-VKESPFFRSLDWQMVFLQKYPPPLIPPR---------------EEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFDTINA-----------------------------------------------------------------
11 PsiBlast_CBE 63.6172% 25 - C1 -3NYO GRK6_HUMAN B:[4-557] -ELENIVANTVLLKAREGGGGNRKG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERQPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQ---KKIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS----------------------------------
2 PsiBlast_PDB 62.8872% 29 - C1 -3NYN GRK6_HUMAN A:[4-557] -ELENIVANTVLLKAREGGGGNRKG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERQPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQ---KKIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS----------------------------------
3 PsiBlast_PDB 62.7372% 30 - C1 -3NYO GRK6_HUMAN A:[4-557] -ELENIVANTVLLKAREGGGGNRKG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERQPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQ---KKIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS----------------------------------
12 PsiBlast_CBE 62.4972% 31 - C1 -3NYN GRK6_HUMAN B:[4-557] -ELENIVANTVLLKAREGGGGNRKG---KSKKWRQMLQFPHISQCEELRLSLERDYHSL--CERQPIGRLLFREFC-----ATRPELSRCVAFLDGVAEYE-V--TPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK-DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---RA-----TG----KMYACKKLEKKRIKKRKGEAMALNEKQI-LEK-V-NS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLHRE-RIVYRDLKPENIL---LDDHGHIRISDLGLAVH-V-PEG-QT-IKGRV----GTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQ---KKIKREEVERLVKEVP----EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSARE-VKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS----------------------------------
84 HHSearch 57.7141% -97 - C1 -4GV1 AKT1_HUMAN A:[3-290] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-RVTMNEFEYLKLLGKGTFGKVILVKE---KA-----TG----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQN-S-RH---PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM---LDKDGHIKITDFGLCKEGI-KDG-AT-MKTFC----GTPEYLAPEVLE-DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEE----IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKE-IMQHRFFAGIVWQHVYEKKLSPPFKPQVT---------------------------------------------------------------------------------------------------------------------------
92 HHSearch 56.4242% -98 * C1 *1O6L AKT2_HUMAN A:[2-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTMNDFDYLKLLGKGTFGKVILVRE---KA-----TG----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQN-T-RH---PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRE----RVFTEERARFYGAEIVSALEYLHSR-DVVYRDIKLENLM---LDKDGHIKITDFGLCKEGI-SDG-AT-MKTFC----GTPEYLAPEVLE-DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQD----HERLFELILMEE----IRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKE-VMEHRFFLSINWQDVVQKKLLPPFKPQVT---------------------------------------------------------------------------------------------------------------------------
48 PsiBlast_CBE 51.1838% -88 - C1 -3TXO A:[23-303] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNFEFIRVLGKGSFGKVMLARV---KE-----TG----DLYAVKVLKKDVILQDDDVECTMTEKRI-LSL-ARNH---PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQK----SRRFDEARARFYAAEIISALMFLHDK-GIIYRDLKLDNVL---LDHEGHCKLADFGMCKEGI-C---------------GTPDYIAPEILQ-EMLYGPAVDWWAMGVLLYEMLCGHAPFEAENE----DDLFEAILNDE----VVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRP------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 50.7037% -97 - C1 -3G51 KS6A3_MOUSE A:[24-304] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVK----KI-----SGSDARQLYAMKVLKKATLKVRD----------I-LVE-V-NH---PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALALDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKESI------------------TVEYMAPEVVN-RRGHTQSADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKAK----LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE-IKRHSFFSTIDWNKLYRREIHPPFKP------------------------------------------------------------------------------------------------------------------------------
71 PsiBlast_CBE 50.4332% -92 - C1 -2UZU KAPCA_BOVIN E:[27-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 50.4332% -90 - C1 -2UZW KAPCA_BOVIN E:[27-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 49.8738% -99 - C1 -2Z7S KS6A1_HUMAN A:[30-308] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLKVLGQGSFGKVFLVRK---VTRPD--SG----HLYAMKVLK------------------I-LAD-V-NH---PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALGLDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKE-------------------GTVEYMAPEVVN-RQGHSHSADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKAK----LGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEE-IKRHVFYSTIDWNKLYRREIKPPFKP------------------------------------------------------------------------------------------------------------------------------
45 PsiBlast_CBE 49.7637% -93 - C1 -3A61 KS6B1_HUMAN A:[19-299] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLRVLGKGGYGKVF--QV---RKVTGANTG----KIFAMKVLK--------------AERNI-LEE-V-KH---PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--I--FMEDTACFYLAEISMALGHLHQK-GIIYRDLKPENIM---LNHQGHVKLTDFG-----------------------GTIEYMAPEILM-RSGHNRAVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKCK----LNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGE-VQAHPFFRHINWEELLARKVEPPFKP------------------------------------------------------------------------------------------------------------------------------
90 HHSearch 49.6438% -91 - C1 -3UBD KS6A3_MOUSE A:[21-304] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADPSQFELLKVLGQGSFGKVFLVKKISGSD-----AR----QLYAMKVLKKATLKVRD-RV------DI-LVE-V-NH---PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV----MFTEEDVKFYLAELALALDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSK------E-KK-AYSFC----GTVEYMAPEVVN-RRGHTQSADWWSFGVLMFEMLTGTLPFQGKD----RKETMTMILKAK----LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE-IKRHSFFSTIDWNKLYRREIHPPFKP------------------------------------------------------------------------------------------------------------------------------
94 HHSearch 49.4239%-101 - C1 -2R5T SGK1_HUMAN A:[32-319] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NP-HAKPSDFHFLKVIGKGSFGKVLLARH---KA-----EE----VFYAVKVLQKKAIL-------------VLLKN-V-KH---PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRE----RCFLEPRARFYAAEIASALGYLHSL-NIVYRDLKPENIL---LDSQGHIVLTDFGLCKE-NIEHN-ST-TSTFC----GTPEYLAPEVLH-KQPYDRTVDWWCLGAVLYEMLYGLPPFYSRN----TAEMYDNILNKP----LQLKPNITNSARHLLEGLLQKDRTKRLGAK-DDFME-IKSHVFFSLINWDDLINKKITPPFNPNVS---------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 49.1932% -91 - C1 -2UZT KAPCA_BOVIN A:[27-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 49.1031% -89 - C1 -2F7Z KAPCA_BOVIN E:[16-317] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQN-TAHLDQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 49.0831% -86 - C1 -2OH0 KAPCA_BOVIN E:[16-317] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQN-TAHLDQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 49.0331% -83 - C1 -2F7E KAPCA_BOVIN E:[16-317] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQN-TAHLDQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 48.9931% -82 - C1 -2OJF KAPCA_BOVIN E:[16-317] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEFLAKAKEDFLKKWENPAQN-TAHLDQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 48.6437% -88 - C1 -3A60 KS6B1_HUMAN A:[19-299] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLRVLGKGGYGKVF--QV---RKVTGANTG----KIFAMKVLKKAM----------KAERNI-LEE-V-KH---PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--I--FMEDTACFYLAEISMALGHLHQK-GIIYRDLKPENIM---LNHQGHVKLTDFGLCKE--------------------TIEYMAPEILM-RSGHNRAVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKCK----LNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGE-VQAHPFFRHINWEELLARKVEPPFKP------------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 48.1438%-101 - C1 -2Z7Q KS6A1_HUMAN A:[30-308] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLKVLGQGSFGKVFLVRK---VTRPD--SG----HLYAMKVL-------------------I-LAD-V-NH---PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALGLDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKE-------------------GTVEYMAPEVVN-RQGHSHSADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKAK----LGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEE-IKRHVFYSTIDWNKLYRREIKPPFKP------------------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 48.1232% -90 - C1 -2UZV KAPCA_BOVIN A:[27-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQFERIKTLGTGSFGRVMLVKH---ME-----TG----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQA-V-NF---PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--R--FSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLL---IDQQGYIQVTDFGFAKR----------VKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPI----QIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVND-IKNHKWFATTDWIAIYQRKVEAPFIP------------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 46.9638% -90 - C1 -2Z7R KS6A1_HUMAN A:[30-308] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLKVLGQGSFGKVFLVRK---VTRPD--SG----HLYAMKVLKKATLKV------------I-LAD-V-NH---PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALGLDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKE-------------------GTVEYMAPEVVN-RQGHSHSADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKAK----LGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEE-IKRHVFYSTIDWNKLYRREIKPPFKP------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 46.9137% -88 - C1 -4EL9 KS6A3_MOUSE A:[25-305] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVK----KI-----SGSDARQLYAMKVLKKATLKVRDRVR------DI-LVE-V-NH---PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALALDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKES----E-KK-AYSFC----GTVEYMAPEVVN-RRGHTQSADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKAK----LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE-IKRHSFFSTIDWNKLYRREIHPPFKP------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 46.4837% -85 - C1 -4GUE KS6A3_MOUSE A:[25-305] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVK----KI-----SGSDARQLYAMKVLKKATLKVRDRV----------LVE-V-NH---PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK----EVMFTEEDVKFYLAELALALDHLHSL-GIIYRDLKPENIL---LDEEGHIKLTDFGLSKE-------KK-AYSFC----GTVEYMAPEVVN-RRGHTQSADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKAK----LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE-IKRHSFFSTIDWNKLYRREIHPPFKP------------------------------------------------------------------------------------------------------------------------------
46 PsiBlast_CBE 46.3237% -93 - C1 -3A60 KS6B1_HUMAN B:[19-300] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLRVLGKGGYGKVF--QV---RKVTGANTG----KIFAMKVLKK-------------------------KH---PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--I--FMEDTACFYLAEISMALGHLHQK-GIIYRDLKPENIM---LNHQGHVKLTDFGLCKES-------------C----GTIEYMAPEILM-RSGHNRAVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKCK----LNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGE-VQAHPFFRHINWEELLARKVEPPFKP-----L------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 45.9438% -90 - C1 -3HDN SGK1_HUMAN A:[40-316] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHFLKVIGKGSFGKVLLARH---KA-----EE----VFYAVKVLQKKAIL-------------V-LLKNV-KH---PFLVGLHFSFQTADKLYFVLDYINGGELFYHL--QR--ERCFLEPRARFYAAEIASALGYLHSL-NIVYRDLKPENIL---LDSQGHIVLTDFGLCKENI-EHN-ST-TSTFC----GTPEYLAPEVLH-KQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK----P----NITNSARHLLEGLLQKDRTKRLGAKDD-FME-IKSHVFFSLINWDDLINKKITPPFNP------------------------------------------------------------------------------------------------------------------------------