@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : GSK3A_HUMAN: (2013-07-20 )
MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLTNSS

Atome Classification :

(54 SA) .........10........20........30........40........50........60........70........80........90........100.......110.....-------..120.......130.......140.......150------.------.....------.160.......170.......180.......190.......200.......210...-....220.......230.......240.......250.......260.......270.-...-----...---280.......290.......300.......310...-----------....320..-------.....330.......340.--.---......350.---......360-.......370..---.....380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEV-------AYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQ------D------KRFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLT-IPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FKFPQIKAH-PWTKVFKSRTPP---EAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLTNSS
49 PsiBlast_CBE 94.0684%-130 - C1 -1H8F GSK3B_HUMAN A:[1-352] -------------------------------------------------------------------------------------------------SKVTTVVATPGQGPDRPQEV-------SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQ------G------KAFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQT-LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FAFPQIKAH-PWTKVFRPRTPP---EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQA----------------------------------
45 PsiBlast_CBE 93.7086%-130 - C1 -3SD0 GSK3B_HUMAN B:[1-349] -------------------------------------------------------------------------------------------------SKVTTVVATPGQGPDRPQEV-------SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQ------D------KRFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQT-LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FKFPQIKAH-PWTKVFRPRTPP---EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR-------------------------------------
48 PsiBlast_CBE 93.0484%-130 - C1 -1H8F GSK3B_HUMAN B:[1-350] -------------------------------------------------------------------------------------------------SKVTTVVATPGQGPDRPQEV-------SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQ------G------KAFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQT-LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FAFPQIKAH-PWTKVFRPRTPP---EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARI------------------------------------
110 HHSearch 92.0583%-132 - C1 -1J1B GSK3B_HUMAN A:[35-388] -------------------------------------------------------------------------------------------------SKVTTVVATPGQGPDRPQEV-------SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQ------D------KRFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQT-LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FKFPQIKAH-PWTKVFRPRTPP---EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAA--------------------------------
46 PsiBlast_CBE 91.8886%-128 - C1 -3SD0 GSK3B_HUMAN A:[1-349] -------------------------------------------------------------------------------------------------SKVTTVVATPGQGPDRPQEV-------SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQ------D------KRFKN------RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQT-LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPN-----VSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-----------GQPIFPGDS-------GVDQLVEIIKVLGTPT-RE--Q---IREMNPNYTE---FKFPQIKAH-PWTKVFRPRTPP---EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR-------------------------------------
118 HHSearch 58.6837%-122 - C1 -3N9X ? A:[11-374] ------------------------------------------------------------------------------------------------------------RENLYFQGIKNVHVPDNYIIKHLIGRGSYGYVYLAYDKNTEKNVAIKKVNRMFEDLID------CKRIL------REITILNRLKSDYIIRLYDLIIPDDLL-KFDELYIVLEIADSDLKKLF----KTPIF-LTEEHIKTILYNLLLGENFIHESGIIHRDLKPANCLLNQD-CSVKVCDFGLARTI--------------H---VVTRWYRAPELILLQENYTKSIDIWSTGCIFAELLNMLQSHINDPTNRFPLFPGSSCFPHEKSNRDQLNIIFNIIGTPT-ED--D---LKNINKPEVIKYIKLFPHRKPI-NLKQKY-PSISD---DGINLLESMLKFNPNKRITIDQALDHPYLKDVRKKKLE-----------------------------------------------------------------------
52 PsiBlast_CBE 55.0835%-141 - C1 -3EZR CDK2_HUMAN A:[6-291] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------VPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADF--------------------------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
50 PsiBlast_CBE 54.2635%-133 - C1 -3NIZ ? A:[23-307] -----------------------------------------------------------------------------------------------------------------------------YQKLEKVGEGTYGVVYKAKDSQGR-IVALKRIR------------------GIPSTAIREISLLKELHHPNIVSLIDVIHS------ERCLTLVFEFMEKDLKKV---LDENKTG-LQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLINSDGA-LKLADFGLARAF--G-IPV-----R--HE-VVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMIT-----------GKPLFPGVT-------DDDQLPKIFSILGTPNPREWPQ---VQEL-PLWKQ---RTFQVFEKK-PWSSIIPGFC-Q---EGIDLLSNMLCFDPNKRISARDAMNHPYFKDL-----------------------------------------------------------------------------
51 PsiBlast_CBE 53.9435%-139 - C1 -3EZV CDK2_HUMAN A:[6-291] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------VPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGL----------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
75 PsiBlast_CBE 53.3535%-140 - C1 -3RAL CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLA---------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
113 HHSearch 52.9234%-124 - C1 -4IC7 MK07_HUMAN A:[57-368] -----------------------------------------------------------------------------------------------------------------------------YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPN------AFDVVTNAKRTL------RELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII----HSSQP-LTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTS-PAEHQYFMTEY---VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA-----------RRQLFPGKN-------YVHQLQLIMMVLGTPS-PA--V---IQAVGAERVRAYIQSLPPRQPV-PWETVY-PGADR---QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDD-EPD---CAPPFDFA---------------------------------------------------------
57 PsiBlast_CBE 52.5835%-136 - C1 -3S1H CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLA---------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
76 PsiBlast_CBE 52.2335%-139 - C1 -3RAK CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLA---------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
61 PsiBlast_CBE 52.2035%-138 - C1 -3RPY CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLA---------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
78 PsiBlast_CBE 51.3935%-133 - C1 -3RAH CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
89 PsiBlast_CBE 51.3735%-134 - C1 -3R83 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
92 PsiBlast_CBE 51.2835%-134 - C1 -3R7U CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
66 PsiBlast_CBE 51.0935%-136 - C1 -3RNI CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
91 PsiBlast_CBE 51.0635%-134 - C1 -3R7V CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
63 PsiBlast_CBE 51.0535%-133 - C1 -3RPR CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
67 PsiBlast_CBE 50.9535%-136 - C1 -3RMF CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLA---------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
96 PsiBlast_CBE 50.9335%-132 - C1 -3R71 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
80 PsiBlast_CBE 50.7935%-133 - C1 -3R9N CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
79 PsiBlast_CBE 50.7335%-129 - C1 -3R9O CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
88 PsiBlast_CBE 50.5735%-133 - C1 -3R8L CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
62 PsiBlast_CBE 50.5535%-134 - C1 -3RPV CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
60 PsiBlast_CBE 50.5435%-135 - C1 -3RZB CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------------------PSTAI-REISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-V-------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
85 PsiBlast_CBE 50.5035%-133 - C1 -3R8U CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
74 PsiBlast_CBE 50.4135%-134 - C1 -3RJC CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
82 PsiBlast_CBE 50.2435%-132 - C1 -3R9D CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
90 PsiBlast_CBE 50.2235%-132 - C1 -3R7Y CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
83 PsiBlast_CBE 50.1935%-136 - C1 -3R8Z CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VP---------THEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
84 PsiBlast_CBE 50.1735%-135 - C1 -3R8V CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
99 PsiBlast_CBE 50.1335%-132 - C1 -3R1Y CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
95 PsiBlast_CBE 50.1235%-133 - C1 -3R73 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
97 PsiBlast_CBE 50.1035%-132 - C1 -3R6X CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
71 PsiBlast_CBE 50.0635%-132 - C1 -3RK9 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
56 PsiBlast_CBE 50.0335%-135 - C1 -3SQQ CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLAR--------------RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
94 PsiBlast_CBE 49.8335%-135 - C1 -3R7E CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
81 PsiBlast_CBE 49.6935%-131 - C1 -3R9H CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
70 PsiBlast_CBE 49.4935%-135 - C1 -3RKB CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
114 HHSearch 49.4334%-120 - C1 -4B99 MK07_HUMAN A:[56-368] -----------------------------------------------------------------------------------------------------------------------------YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPN------AFDVVTNAKRTL------RELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII----HSSQP-LTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGL---QYFM-----TEY---VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA-----------RRQLFPGKN-------YVHQLQLIMMVLGTPS-PA--V---IQ-----RVRAYIQSLPPRQPV-PWETVYP-GADR---QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE-PD---CAPPFDFAF--------------------------------------------------------
86 PsiBlast_CBE 49.3735%-131 - C1 -3R8P CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
87 PsiBlast_CBE 49.3535%-132 - C1 -3R8M CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G------------E--VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
59 PsiBlast_CBE 49.2735%-133 - C1 -3S00 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
98 PsiBlast_CBE 49.2635%-129 - C1 -3R28 CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----------------TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------
53 PsiBlast_CBE 49.2435%-126 - C1 -4GCJ CDK2_HUMAN A:[12-297] -----------------------------------------------------------------------------------------------------------------------------FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL------D------TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENK------LYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI-KLADFGLARAF--G-VPV-----RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDS-------EIDQLFRIFRTLGTPD-EV--VWPGVTSM-PDYKP----SFPKWARQ-DFSKV----VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-----------------------------------------------------------------------------