@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : IKKE_HUMAN: (2013-07-21 )
MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCVLEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSVAGTPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLSSLNRELVKSRDQVHEDRSIQQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV
Atome Classification :
(29 SA)
.........10........20...---...---..30........40-----...--------.....------50-...--.--.....60..-......70-........80..-......90.....-.---..100.-....-..110.......120.......130.......140-.......150.......-160.-..---....-170..-.....180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470-..--------.....480-.......490.......500.......510.......520--........530...-....540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQSTANYLWHTDDLLGQGATASVY---KAR---NKKSGELVAVKVFN-----TTS--------YLRPR------E--VQV--R--EFEVLRKLN-HQNIVKLF-AVEETGGSRQKV-LVMEYCSSGSLLS-V---LESPEN-AFGL-PEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIM-RLVGEEGQSIYKLTDFG-AARE-LD---DDEK-FVSVY-GTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCVLEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSL-GT--------ERFSSVAG-TPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLS---SLNRELVKSRDQVH-EDRSIQQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV
5
PsiBlast_PDB
94.80
50%
-98
- C2 -
4IW0
1
TBK1_HUMAN
A:
[3-657]
-
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---------------------------------------------------------------------
4
PsiBlast_PDB
92.66
50%
-100
- C2 -
4IWO
1
TBK1_HUMAN
A:
[5-659]
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---------------------------------------------------------------------
1
PsiBlast_PDB
92.46
50%
-103
- C2 -
4IM3
1
TBK1_HUMAN
A:
[7-662]
M
Q
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---------------------------------------------------------------------
3
PsiBlast_PDB
90.61
50%
-98
- C2 -
4IWQ
1
TBK1_HUMAN
A:
[4-658]
-
Q
S
T
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T
E
E
Y
L
H
P
D
M
Y
E
------------
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
R
M
V
I
H
V
F
S
L
Q
Q
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
T
I
F
H
E
L
V
Y
K
Q
T
K
I
I
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
P
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
V
S
R
E
P
L
N
T
I
G
L
I
Y
E
K
I
S
L
P
K
V
H
P
R
Y
D
L
D
G
D
A
S
M
A
K
A
I
T
G
V
V
C
Y
A
C
R
I
A
S
T
L
L
L
Y
Q
E
L
M
R
K
G
I
R
W
L
I
E
L
I
K
D
D
Y
N
E
T
V
H
K
K
T
E
V
V
I
T
L
D
F
C
I
R
N
I
--------
E
K
T
V
K
V
Y
E
-------
L
G
E
I
S
D
I
H
T
K
L
L
R
L
S
S
S
Q
G
T
I
E
T
S
L
Q
D
I
D
S
R
L
S
PGG
S
L
A
D
A
W
A
H
Q
E
G
T
H
P
-
K
D
R
N
V
E
K
L
Q
V
L
L
N
C
M
T
E
I
Y
Y
Q
F
K
K
D
K
A
E
R
R
L
A
Y
N
E
E
Q
I
H
K
F
D
K
Q
K
L
Y
Y
H
A
T
K
A
M
T
H
F
T
D
E
C
V
K
K
Y
E
A
F
L
N
K
S
E
E
W
I
R
K
M
L
H
L
R
K
Q
L
L
S
L
T
N
Q
C
F
D
I
E
E
E
V
S
K
Y
Q
E
Y
T
N
E
L
Q
E
---------------------------------------------------------------------
6
PsiBlast_PDB
90.04
52%
-98
- C2 -
4JL9
1
?
A:
[3-612]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
Y
A
V
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
D
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
---------
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
R
K
D
H
Q
K
K
Y
G
A
T
V
D
L
W
S
V
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
L
S
C
S
L
S
Q
G
L
Q
A
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
V
L
H
R
M
V
I
H
V
F
S
L
Q
H
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
A
V
F
H
E
L
V
Y
K
Q
T
K
I
V
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
L
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
T
S
R
E
Q
L
N
T
V
G
L
R
Y
E
K
I
S
L
P
K
I
H
P
R
Y
D
L
D
G
D
A
S
M
A
K
A
V
T
G
V
V
C
Y
A
C
R
T
A
S
T
L
L
L
Y
Q
E
L
M
R
K
G
V
R
W
L
V
E
L
V
K
D
D
Y
N
E
T
V
H
K
K
T
E
V
V
I
T
L
D
F
C
I
-
R
N
I
E
K
T
V
K
V
Y
E
K
L
M
K
V
---
N
----
E
L
G
E
I
S
D
I
H
T
K
L
L
R
L
S
S
S
Q
G
T
I
E
S
S
L
Q
D
I
S
S
R
L
S
PG-
G
L
L
A
D
T
W
A
H
Q
E
G
T
H
P
R
D
R
N
V
E
K
L
Q
V
L
L
N
C
I
T
E
I
Y
Y
Q
F
K
K
D
K
A
E
R
R
L
A
Y
N
E
E
Q
I
H
K
F
D
K
Q
K
L
Y
Y
H
A
T
K
A
M
S
H
F
S
E
E
C
V
R
K
Y
E
A
------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.73
50%
-94
- C2 -
4IWP
1
TBK1_HUMAN
A:
[4-658]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
F
A
I
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
D
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
---------------
G
T
E
E
Y
L
H
P
D
M
Y
E
------------
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
R
M
V
I
H
V
F
S
L
Q
Q
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
T
I
F
H
E
L
V
Y
K
Q
T
K
I
I
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
P
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
V
S
R
E
P
L
N
T
I
G
L
I
Y
E
K
I
S
L
P
K
V
H
P
R
Y
D
L
D
G
D
A
S
M
A
K
A
I
T
G
V
V
C
Y
A
C
R
I
A
S
T
L
L
L
Y
Q
E
L
M
R
K
G
I
R
W
L
I
E
L
I
K
D
D
Y
N
E
T
V
H
K
K
T
E
V
V
I
T
L
D
F
C
I
R
N
I
--------
E
K
T
V
K
V
Y
-----
A
A
E
L
G
E
I
S
D
I
H
T
K
L
L
R
L
S
S
S
Q
G
T
I
E
T
S
L
Q
D
I
D
S
R
L
S
PGG
S
L
A
D
A
W
A
H
Q
E
G
T
H
P
-
K
D
R
N
V
E
K
L
Q
V
L
L
N
C
M
T
E
I
Y
Y
Q
F
K
K
D
K
A
E
R
R
L
A
Y
N
E
E
Q
I
H
K
F
D
K
Q
K
L
Y
Y
H
A
T
K
A
M
T
H
F
T
D
E
C
V
K
K
Y
E
A
F
L
N
K
S
E
E
W
I
R
K
M
L
H
L
R
K
Q
L
L
S
L
T
N
Q
C
F
D
I
E
E
E
V
S
K
Y
Q
E
Y
T
N
E
L
Q
E
---------------------------------------------------------------------
7
PsiBlast_PDB
88.35
52%
-101
- C2 -
4JLC
1
?
A:
[3-612]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
Y
A
V
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
D
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
---------
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
R
K
D
H
Q
K
K
Y
G
A
T
V
D
L
W
S
V
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
L
S
C
S
L
S
Q
G
L
Q
A
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
V
L
H
R
M
V
I
H
V
F
S
L
Q
H
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
A
V
F
H
E
L
V
Y
K
Q
T
K
I
V
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
L
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
T
S
R
E
Q
L
N
T
V
G
L
R
Y
E
K
I
S
L
P
K
I
H
P
R
Y
D
L
D
G
D
A
S
M
A
K
A
V
T
G
V
V
C
Y
A
C
R
T
A
S
T
L
L
L
Y
Q
E
L
M
R
K
G
V
R
W
L
V
E
L
V
K
D
D
Y
N
E
T
V
H
K
K
T
E
V
V
I
T
L
D
F
C
I
-
R
N
I
E
K
T
V
K
V
Y
E
K
L
M
K
V
---
N
----
E
L
G
E
I
S
D
I
H
T
K
L
L
R
L
S
S
S
Q
G
T
I
E
S
S
L
Q
D
I
S
S
R
L
S
PG-
G
L
L
A
D
T
W
A
H
Q
E
G
T
H
P
R
D
R
N
V
E
K
L
Q
V
L
L
N
C
I
T
E
I
Y
Y
Q
F
K
K
D
K
A
E
R
R
L
A
Y
N
E
E
Q
I
H
K
F
D
K
Q
K
L
Y
Y
H
A
T
K
A
M
S
H
F
S
E
E
C
V
R
K
Y
E
A
------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
73.05
67%
-108
- C2 -
4EUT
1
TBK1_HUMAN
B:
[4-385]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
F
A
I
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
N
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
E
Q
-
F
V
S
L
Y
-
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
R
-------
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
R
M
V
I
H
V
F
S
L
Q
Q
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
T
I
F
H
E
L
V
Y
K
Q
T
K
I
I
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
P
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
HHSearch
71.09
67%
-102
- C2 -
4EUT
1
TBK1_HUMAN
A:
[4-387]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
F
A
I
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
N
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
E
Q
-
F
V
S
L
Y
-
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
--
D
H
Q
K
K
Y
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
R
M
V
I
H
V
F
S
L
Q
Q
M
T
A
H
K
I
Y
I
H
S
Y
N
T
A
T
I
F
H
E
L
V
Y
K
Q
T
K
I
I
S
S
N
Q
E
L
I
Y
E
G
R
R
L
V
L
E
P
G
R
L
A
Q
H
F
P
K
T
T
E
E
N
P
I
F
V
V
S
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.65
72%
-92
- C2 -
4EUU
6
TBK1_HUMAN
A:
[4-309]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
F
A
I
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
N
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
E
Q
-
F
V
S
L
Y
-
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
R
K
D
H
Q
K
K
Y
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
46.27
72%
-56
- C2 -
4EUU
6
TBK1_HUMAN
B:
[4-309]
-
Q
S
T
S
N
H
L
W
L
L
S
D
I
L
G
Q
G
A
T
A
N
V
F
---
R
G
R
---
H
K
K
T
G
D
L
F
A
I
K
V
F
N
-----
N
I
S
--------
F
L
R
P
V
------
D
--
V
Q
M
--
R
--
E
F
E
V
L
K
K
L
N
-
H
K
N
I
V
K
L
F
-
A
I
E
E
E
T
T
T
R
H
K
V
-
L
I
M
E
F
C
P
C
G
S
L
Y
T
-
V
---
L
E
E
P
S
N
-
A
Y
G
L
-
P
E
S
E
F
L
I
V
L
R
D
V
V
G
G
M
N
H
L
R
E
N
G
I
V
H
R
N
I
K
P
G
N
I
M
-
R
V
I
G
E
D
G
Q
S
V
Y
K
L
T
D
F
G
-
A
A
R
E
-
L
E
---
D
D
E
Q
-
F
V
-
L
Y
-
G
T
E
E
Y
L
H
P
D
M
Y
E
R
A
V
L
R
K
D
H
Q
K
K
Y
G
A
T
V
D
L
W
S
I
G
V
T
F
Y
H
A
A
T
G
S
L
P
F
R
P
F
E
G
P
R
R
N
K
E
V
M
Y
K
I
I
T
G
K
P
S
G
A
I
S
G
V
Q
K
A
E
N
G
P
I
D
W
S
G
D
M
P
V
S
C
S
L
S
R
G
L
Q
V
L
L
T
P
V
L
A
N
I
L
E
A
D
Q
E
K
C
W
G
F
D
Q
F
F
A
E
T
S
D
I
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
39.05
32%
-74
- C2 -
2YAA
1
DAPK2_MOUSE
B:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
-----
K
R
Q
--------
S
R
A
S
R
RGVC
R
E
E
--
I
E
---
R
--
E
V
S
I
L
R
Q
V
L
-
H
P
N
I
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
37.94
32%
-74
- C2 -
2CKE
1
DAPK2_HUMAN
B:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
K
R
QSR
A
S
R
--------
R
G
V
S
R
------
E
--
E
I
E
--
R
--
E
V
S
I
L
R
Q
V
L
-
H
H
N
V
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
37.69
32%
-72
- C2 -
2YAA
1
DAPK2_MOUSE
A:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
-----
K
R
Q
--------
S
R
A
S
R
RGVC
R
E
E
--
I
E
---
R
--
E
V
S
I
L
R
Q
V
L
-
H
P
N
I
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
37.01
33%
-67
- C2 -
2WEL
7
KCC2D_HUMAN
A:
[12-206]
--------------
L
G
K
G
A
F
S
V
V
R
---
R
C
M
---
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
-----
T
K
K
---------
L
S
A
R
------
D
--
H
Q
K
L
E
R
--
E
A
R
I
C
R
L
L
K
-
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
---
Y
-
L
V
F
D
L
V
T
G
G
E
L
F
E
-
D
---
I
V
A
R
E
Y
----
Y
-
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
S
K
G
A
A
V
-
K
L
A
D
F
G
-
L
A
I
E
-
V
Q
---
G
D
Q
Q
A
W
F
G
F
A
-
G
T
P
G
Y
L
S
P
E
-----
V
L
R
K
---
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
36.62
32%
-70
- C2 -
2CKE
1
DAPK2_HUMAN
C:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
KRQSR
A
S
R
--------
R
G
V
S
R
------
E
--
E
I
E
--
R
--
E
V
S
I
L
R
Q
V
L
-
H
H
N
V
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
36.24
32%
-72
- C2 -
2CKE
1
DAPK2_HUMAN
D:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
KRQSR
A
S
R
--------
R
G
V
S
R
------
E
--
E
I
E
--
R
--
E
V
S
I
L
R
Q
V
L
-
H
H
N
V
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
35.96
32%
-70
- C2 -
2CKE
1
DAPK2_HUMAN
A:
[20-219]
--------------
L
G
S
G
Q
F
A
I
V
K
---
K
C
R
---
E
K
S
T
G
L
E
Y
A
A
K
F
I
K
K
R
QSR
A
S
R
--------
R
G
V
S
R
------
E
--
E
I
E
--
R
--
E
V
S
I
L
R
Q
V
L
-
H
H
N
V
I
T
L
H
-
D
V
Y
E
--
N
R
T
D
V
V
-
L
I
L
E
L
V
S
G
G
E
L
F
D
-
F
---
L
A
Q
K
E
S
----
L
-
S
E
E
E
A
T
S
F
I
K
Q
I
L
D
G
V
N
Y
L
H
T
K
K
I
A
H
F
D
L
K
P
E
N
I
M
-
L
L
D
K
N
I
P
I
P
H
I
K
L
I
D
F
G
-
L
A
H
E
-
I
E
---
D
G
V
E
-
F
K
N
I
F
-
G
T
P
E
F
V
A
P
E
I
V
--------
N
Y
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
34.44
32%
-69
- C2 -
1PHK
1
PHKG1_RABIT
A:
[23-229]
------------
E
I
L
G
R
G
V
S
S
V
V
R
---
R
C
I
---
H
K
P
T
C
K
E
Y
A
V
K
I
I
D
-----
V
T
G
GGSFS
A
E
E
V
Q
E
L
R
------
E
--
A
T
L
--
K
--
E
V
D
I
L
R
K
V
S
G
H
P
N
I
I
Q
L
K
-
D
T
Y
E
T
N
T
F
F
--
F
-
L
V
F
D
L
M
K
K
G
E
L
F
D
-
Y
---
L
T
E
----
K
V
T
L
-
S
E
K
E
T
R
K
I
M
R
A
L
L
E
V
I
C
A
L
H
K
L
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
---
D
D
D
M
N
I
-
K
L
T
D
F
G
-
F
S
C
Q
-
L
D
---
P
G
E
K
-
L
R
E
V
C
-
G
T
P
S
Y
L
A
P
E
I
I
E
C
S
M
--
N
D
N
H
P
G
Y
G
K
E
V
D
M
W
S
T
G
V
I
M
Y
T
L
L
A
G
S
P
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
33.77
32%
-69
- C2 -
3A61
1
KS6B1_HUMAN
A:
[24-230]
-------------
V
L
G
K
G
G
Y
G
K
V
F
---
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
------------------------------------A-
E
R
N
I
L
E
E
V
K
-
H
P
F
I
V
D
L
I
-
Y
A
F
Q
T
G
G
--
K
L
Y
-
L
I
L
E
Y
L
S
G
G
E
L
F
M
-
Q
---
L
E
R
-
E
G
-
I
F
---
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
-
L
----
N
H
Q
G
H
V
K
L
T
D
F
G
----------------------
G
T
I
E
Y
M
A
P
E
I
----
L
M
R
S
G
H
N
R
A
----
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
T
---
G
E
N
R
K
K
T
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
33.00
32%
-64
- C2 -
3A60
1
KS6B1_HUMAN
A:
[24-230]
-------------
V
L
G
K
G
G
Y
G
K
V
F
---
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
K
-----
K
A
M
----------------------------KA
E
R
N
I
L
E
E
V
K
-
H
P
F
I
V
D
L
I
-
Y
A
F
Q
T
G
G
--
K
L
Y
-
L
I
L
E
Y
L
S
G
G
E
L
F
M
-
Q
---
L
E
R
-
E
G
-
I
F
---
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
-
L
----
N
H
Q
G
H
V
K
L
T
D
F
G
-
L
C
K
E
------------------
T
I
E
Y
M
A
P
E
I
----
L
M
R
S
G
H
N
R
A
----
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
T
---
G
E
N
R
K
K
T
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
31.05
35%
-70
- C2 -
2Z7Q
1
KS6A1_HUMAN
A:
[35-230]
-------------
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
T
---
R
P
D
S
G
H
L
Y
A
M
K
V
L
------------------------------------------
I
L
A
D
V
N
-
H
P
F
V
V
K
L
H
-
Y
A
F
Q
T
E
G
--
K
L
Y
-
L
I
L
D
F
L
R
G
G
D
L
F
T
-
R
---
L
-
S
K
E
V
-
M
F
---
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
---
L
L
D
E
E
G
H
--
I
K
L
T
D
F
G
-
L
S
K
E
-----------------
G
T
V
E
Y
M
A
P
E
V
V
N
R
--------
Q
G
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
30.50
35%
-66
- C2 -
3G51
1
KS6A3_MOUSE
A:
[31-226]
-------------
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
S
D
A
R
Q
L
Y
A
M
K
V
L
K
K
----
A
T
L
--------
K
V
R
D
---------------------
I
L
V
E
V
N
-
H
P
F
I
V
K
L
H
-
Y
A
F
Q
T
E
G
--
K
L
Y
-
L
I
L
D
F
L
R
G
G
D
L
F
T
-
R
---
L
-
S
K
E
V
-
M
F
---
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
---
L
L
D
E
E
G
H
--
I
K
L
T
D
F
G
-
L
S
K
E
S
I
----------------
T
V
E
Y
M
A
P
E
V
V
N
R
---
R
G
H
T
Q
S
A
-----
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
25.49
31%
-60
- C2 -
3ZDU
2
CDKL3_HUMAN
A:
[4-203]
-------
M
Y
E
T
L
G
K
V
G
E
G
S
Y
G
T
V
M
---
K
C
K
---
H
K
N
T
G
Q
I
V
A
I
K
I
F
-----------------
Y
-----------N
K
I
A
M
--
R
--
E
I
K
F
L
K
Q
F
H
-
H
E
N
L
V
N
L
I
----
E
V
F
R
Q
K
K
K
I
H
L
V
F
E
F
I
D
H
----
T
-
V
---
L
D
E
L
Q
H
Y
C
H
G
L
-
E
S
K
R
L
R
K
Y
L
F
Q
I
L
R
A
I
D
Y
L
H
S
N
N
I
I
H
R
D
I
K
P
E
N
I
---
L
V
S
Q
S
G
--
I
T
K
L
C
D
F
G
-
F
A
R
T
---DIY
D
D
E
------
V
-
A
T
R
W
Y
R
A
P
E
L
----
V
L
K
---
D
T
S
Y
G
K
P
V
D
I
W
A
L
G
C
M
I
I
E
M
A
T
G
N
-
P
Y
L
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
25.30
33%
-60
- C2 -
2JAM
3
KCC1G_HUMAN
B:
[15-207]
------------
E
V
L
G
S
G
A
F
S
E
V
F
---
L
V
K
---
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
-----
K
--------------
S
------
S
--
L
E
---
N
--
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
-
D
I
Y
E
S
--
T
T
H
Y
Y
-
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
---
L
E
R
------
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
I
-
M
I
T
D
F
G
-
L
S
K
--
M
E
---
Q
N
G
I
-
M
S
T
A
C
-
G
T
P
G
Y
V
A
P
E
V
----
L
A
Q
K
P
Y
S
K
A
----
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
23.92
33%
-60
- C2 -
2JAM
3
KCC1G_HUMAN
A:
[15-207]
------------
E
V
L
G
S
G
A
F
S
E
V
F
---
L
V
K
---
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
-----
K
--------------
S
------
S
--
L
E
---
N
--
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
-
D
I
Y
E
S
--
T
T
H
Y
Y
-
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
---
L
E
R
------
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
I
-
M
I
T
D
F
G
-
L
S
K
--
M
E
---
Q
N
G
I
-
M
S
T
A
C
-
G
T
P
G
Y
V
A
P
E
V
----
L
A
Q
K
P
Y
S
K
A
----
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
23.78
32%
-49
- C2 -
3A60
1
KS6B1_HUMAN
B:
[24-230]
-------------
V
L
G
K
G
G
Y
G
K
V
F
---
Q
V
R
KVT
G
A
N
T
G
K
I
F
A
M
K
V
L
K
-----
K
----------------------------------------
K
-
H
P
F
I
V
D
L
I
-
Y
A
F
Q
T
G
G
--
K
L
Y
-
L
I
L
E
Y
L
S
G
G
E
L
F
M
-
Q
---
L
E
R
-
E
G
-
I
F
---
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
-
L
----
N
H
Q
G
H
V
K
L
T
D
F
G
-
L
C
K
E
-
S
--------------C
G
T
I
E
Y
M
A
P
E
I
----
L
M
R
S
G
H
N
R
A
----
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
T
---
G
E
N
R
K
K
T
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
17.06
31%
-45
- C2 -
2J51
5
SLK_HUMAN
A:
[38-234]
-------
F
W
E
I
I
G
E
L
G
D
G
A
F
G
K
V
Y
---
K
A
Q
---
N
K
E
T
S
V
L
A
A
A
K
V
I
D
-----
T
K
S
--------
E
E
E
L
E
------
D
--
Y
M
V
-----
E
I
D
I
L
A
S
C
D
-
H
P
N
I
V
K
L
---
L
D
A
F
Y
Y
E
N
N
L
W
-
I
L
I
E
F
C
A
G
G
A
V
D
A
-
V
M
L
E
L
E
R
P
------
L
-
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
-----
I
K
L
A
D
F
G
V
S
A
K
N
-
T
R
---
T
I
Q
R
-
R
D
S
F
I
-
G
T
P
Y
W
M
A
P
---
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
15.38
31%
-44
- C2 -
2UV2
6
SLK_HUMAN
A:
[38-234]
-------
F
W
E
I
I
G
E
L
G
D
--
F
G
K
V
Y
---
K
A
Q
---
N
K
E
T
S
V
L
A
A
A
K
V
I
D
-----
T
K
S
--------
E
E
E
L
E
------
D
--
Y
M
V
-----
E
I
D
I
L
A
S
C
D
-
H
P
N
I
V
K
L
---
L
D
A
F
Y
Y
E
N
N
L
W
-
I
L
I
E
F
C
A
G
G
A
V
D
A
-
V
M
L
E
L
E
R
P
------
L
-
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
-----
I
K
L
A
D
F
G
V
S
A
K
N
-
T
R
---
T
I
Q
R
-
R
D
S
F
I
-
G
T
P
Y
W
M
A
P
---
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------