@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : IRAK4_HUMAN: (2013-07-21 )
MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS

Atome Classification :

(57 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200...--.-...-210.......220.......230.......240.......250........260.......270.....----..280--.........290.......300...---..--..310.......320.......330.......340.......350........-.360.----.----..-....370.......380--.-......390---........400.......410......-.420.......430.......440.......450.......460
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS--
4 PsiBlast_PDB 87.6999% -99 - C2 -2OIC IRAK4_HUMAN A:[4-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKK-----------LKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARA------TVMTSRIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
116 HHSearch 87.09100%-100 - C2 -2NRU IRAK4_HUMAN A:[11-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
1 PsiBlast_PDB 86.8099% -95 - C2 -2NRY IRAK4_HUMAN A:[11-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAA---ITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARAS-----TVMTSRIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
23 PsiBlast_CBE 69.6599% -41 - C2 -2NRU IRAK4_HUMAN B:[10-305] ------------------------------------------------------------------------------------------------------------------------------------------------------------------TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVM--RIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
21 PsiBlast_CBE 69.2699% -39 - C2 -2NRU IRAK4_HUMAN D:[11-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVM--RIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
22 PsiBlast_CBE 69.0999% -39 - C2 -2NRU IRAK4_HUMAN C:[11-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--N-NTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF-SSDGDDLCLVYVYMPNGSLLDRLSCL----DGT----PPLSWHMRCKIAQGAANGINFLHEN---HH--IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVM--RIVG--TTAYMAPE-ALR-G----E----IT-PKSDIYSFGVVLLEIIT--G-LPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT----
10 PsiBlast_PDB 64.2035% -94 - C2 -3UIM BAK1_ARATH A:[15-307] ------------------------------------------------------------------------------------------------------------------------------------------------------------------GQLKRFSLRELQVASDNFSNK------NILGRGGFGKVYKGRLA-D-GTL-VAVKRLK---E-----GELQFQTEVEMISMAVHRNLLRLRGF-CMTPTERLLVYPYMANGSVA---SCLRERPESQ----PPLDWPKRQRIALGSARGLAYLHDHCDPKI--IHRDVKAANILLDEEFEAVVGDFGLAKLMD-YKDTHVTTAVRG--TIGHIAPE-YLSTG----K----SS-EKTDVFGYGVMLLELIT--G-QRAFDLARLANDDDVMLLDWVKGLL-KEKKLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRMLE-------
111 HHSearch 57.0931% -77 - C2 -3OMV RAF1_HUMAN A:[41-301] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STRIGSGSFGTVYKGKW--H-G-D-VAVKILKVV-D-PTPEQFQAFRNEVAVLRKTRHVNILLFMGY-MTK-DNLAIVTQWCEGSSLYKHLHVQ------E----TKFQMFQLIDIARQTAQGMDYLHAK---NI--IHRDMKSNNIFLHEGLTVKIGDFGLATV------------PTG--SVLWMAPE-VIR-MQDNNP----FS-FQSDVYSYGIVLYELMT--G-ELPYSHIN----NRDQIIFMV---G------RGYASPDL-SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHS--
83 PsiBlast_CBE 57.0531% -72 - C2 -3U4W SRC_CHICK A:[14-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
87 PsiBlast_CBE 56.9931% -77 - C2 -4DGG SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG-----------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
86 PsiBlast_CBE 56.9531% -75 - C2 -4DGG SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKP-----------AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARL-------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
82 PsiBlast_CBE 56.5531% -79 - C2 -3U51 SRC_CHICK A:[14-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG-----------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
28 PsiBlast_CBE 56.1531% -76 - C2 -4EHE B:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
102 Fugue 56.0631% -91 - C2 -1BYG CSK_HUMAN A:[15-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------GWAL---------------------NMKELKLLQTIGKGEFGDVMLGDYRG---NK-VAVKCIK--------NDAQAFLAEASVMTQLRHSNLVQLLGVIV--EEGLYIVTEYMAKGSLVDYLRSRG-----R----SVLGGDCLLKFSLDVCEAMEYLEGN---NF--VHRDLAARNVLVSEDNVAKVSDFG-------------------LLPVKWTAPE-ALREK----K----FS-TKSDVWSFGILLWEIYSFGR-VPYPRIPL-----KDVVPRVEK-------------GYKM-DAPDGCP-PAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHEL
65 PsiBlast_CBE 55.7131% -75 - C2 -2OFV LCK_HUMAN A:[25-272] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLKQ-----G-------LAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLA--------------------IKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
81 PsiBlast_CBE 55.5631% -78 - C2 -3U51 SRC_CHICK B:[14-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG---------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
100 PsiBlast_CBE 55.4631% -74 - C2 -3EN4 SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARL-----------AKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
89 PsiBlast_CBE 55.4631% -73 - C2 -4AGW SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADF----------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
90 PsiBlast_CBE 55.2931% -77 - C2 -3UQG SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLI----------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
92 PsiBlast_CBE 55.0531% -78 - C2 -3UQF SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLA-------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
71 PsiBlast_CBE 54.7531% -72 - C2 -2H8H SRC_HUMAN A:[274-522] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
30 PsiBlast_CBE 54.7131% -80 - C2 -4E4X B:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
95 PsiBlast_CBE 54.6731% -73 - C2 -3F6X SRC_CHICK D:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIE----------KF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
97 PsiBlast_CBE 54.6231% -72 - C2 -3F6X SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGC-GEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLI-----------KF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
93 PsiBlast_CBE 54.6231% -71 - C2 -3G6G SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADF---------------GAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
31 PsiBlast_CBE 54.5631% -83 - C2 -4E4X BRAF_HUMAN A:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWS-------LSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
85 PsiBlast_CBE 54.5031% -73 - C2 -4FIC SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQ---GEVWMGTW--N-GTTRVAIKTLKP-------------LQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG-----------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
91 PsiBlast_CBE 54.4931% -71 - C2 -3UQF SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKT--------PE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG---------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
99 PsiBlast_CBE 54.4331% -72 - C2 -3EN5 SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQG-FGEVWMGTW--N-GTTRVAIKTL-------------------QVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVA------------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
74 PsiBlast_CBE 54.3731% -71 - C2 -2BDF SRC_HUMAN A:[18-268] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIE-----------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
67 PsiBlast_CBE 54.3531% -71 - C2 -2OF4 LCK_HUMAN A:[20-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLK-----QGSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
72 PsiBlast_CBE 54.2331% -65 * C2 *2BDJ SRC_HUMAN A:[18-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIE-----------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFT---
96 PsiBlast_CBE 54.1831% -71 - C2 -3F6X SRC_CHICK C:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKP-----PE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIE----------KF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
73 PsiBlast_CBE 54.1831% -72 - C2 -2BDF SRC_HUMAN B:[18-268] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIE---------AKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
66 PsiBlast_CBE 54.1231% -69 - C2 -3BYU LCK_HUMAN A:[26-273] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLKQ-----GSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGL---------------KF---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
88 PsiBlast_CBE 54.0031% -70 - C2 -4AGW SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADF----------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
84 PsiBlast_CBE 53.9531% -73 - C2 -4FIC SRC_CHICK B:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTL-------------------QVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG-----------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
94 PsiBlast_CBE 53.8131% -75 - C2 -3G6G SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFG--------------GAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
98 PsiBlast_CBE 53.6231% -75 - C2 -3EN7 SRC_CHICK A:[25-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQ---GEVWMGTW--N---TRVAIKTLKP------------FLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----MGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADF----------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS--
14 PsiBlast_PDB 53.5831% -69 - C2 -1UWH BRAF_HUMAN A:[13-258] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-ST-APQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATV------------LSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
63 PsiBlast_CBE 53.5531% -68 - C2 -2PL0 LCK_HUMAN A:[30-277] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLKQ-----GSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLERGY------RM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
68 PsiBlast_CBE 53.5431% -72 - C2 -2OF2 LCK_HUMAN A:[20-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLK-----QGSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
77 PsiBlast_CBE 53.4031% -70 - C2 -1Y57 SRC_HUMAN A:[191-441] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-----MSPEAFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
76 PsiBlast_CBE 53.3931% -69 - C2 -2SRC SRC_HUMAN A:[191-439] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-----MSPEAFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
44 PsiBlast_CBE 53.2531% -71 - C2 -3PRI B:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATV------------LSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
45 PsiBlast_CBE 53.1731% -70 - C2 -3PRI BRAF_HUMAN A:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATV------------LSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
64 PsiBlast_CBE 53.0931% -76 - C2 -2OFV ? B:[25-272] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLKQ-----G-----AFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLARLIED--------------PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYP-------IQNLE-------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
62 PsiBlast_CBE 52.7431% -66 - C2 -3B2W LCK_HUMAN A:[25-272] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLKQ-----GSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA--GAKF---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
79 PsiBlast_CBE 52.6332% -69 - C2 -1YOM SRC_HUMAN B:[22-272] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMNKGSLLDFLKGE----TGKYLRLPQLV-DMSAQIASGMA----YVERM---NY--VHRDLRAANILVGENLVCKVADF------------------F---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
29 PsiBlast_CBE 52.5631% -74 - C2 -4EHE BRAF_HUMAN A:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATVKSR----------SG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
70 PsiBlast_CBE 52.4531% -59 - C2 -3MPM LCK_HUMAN A:[16-263] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLK-----QGSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRNLRAANILVSDTLSCKIADFGLARLIEDNEYTAR----F---PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
78 PsiBlast_CBE 52.4131% -66 - C2 -1KSW SRC_HUMAN A:[191-439] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-----MSPEAFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVGEYMSKGSLLDFLKGE----TGK----Y-LRLPQLVDMAAQIASGMAYVERM---NY--VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKF---PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
69 PsiBlast_CBE 52.0131% -67 - C2 -2OG8 ? B:[15-262] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--NGHTK-VAVKSLK-----QGSMSPDAFLAEANLMKQLQHQRLVRLYAV-VTQ-EPIYIITEYMENGSLVDFLKTP----SGI----K-LTINKLLDMAAQIAEGMAFIEER---NY--IHRDLRAANILVSDTLSCKIADFGLA-------------------PIKWTAPE-AINYG----T----FT-IKSDVWSFGILLTEIVT---------HGR----IPYPGMTNPEVIQNLER------GYRM-VRPDNCP-EELYQLMRLCWKERPEDRPTFDYLRSVLEDF-----
33 PsiBlast_CBE 51.8331% -71 - C2 -4E26 BRAF_HUMAN A:[41-286] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRIGSGSFGTVYKGKW--H-GD--VAVKMLN--VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY-STK-PQLAIVTQWCEGSSLYHHLHII----ETK----FEMI--KLIDIARQTAQGMDYLHAK---SI--IHRDLKSNNIFLHEDLTVKIGDFGLATVKSR------FEQLSG--SILWMAPE-VIR-M----QDKNPYS-FQSDVYAFGIVLYELMT--GQLPYSNINN----RDQIIFMVG----------RGYLSPDL-SKVRSNCPKAMKRLMAECLKKKRDERP-----------------
80 PsiBlast_CBE 50.4832% -67 - C2 -1YOM SRC_HUMAN A:[22-272] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGCFGEVWMGTW--N-GTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAV-VSE-EPIYIVTEYMNKGSLLDFLKGE----TGKYLRLPQLV-DMSAQIASGMA----YVERM---NY--VHRDLRAANILVGENLVCKVADF----------------------PIKWTAPEAALY-G----R----FT-IKSDVWSFGILLTELTT---------KGR----VPYPGMVNREVLDQVERGYR--------MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS--
61 PsiBlast_CBE 47.7436% -91 - C2 -3P86 CTR1_ARATH A:[44-234] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIGAGSFGTVHRAEW--H-GSD-VAVKILMEQ-DFHAERV-NEFLREVAIMKRLRHPNIVLFMGA-VTQPPNLSIVTEYLSRGSLYRLLHKS----GAR----EQLDERRRLSMAYDVAKGMNYLHNR---NPPIVHRNLKSPNLLVDKKYTVKVCDF-------------------G--TPEWMAPE-VLR-D----E----PSNEKSDVYSFGVILWELAT----------------------------------------------------------------------------------------
75 PsiBlast_CBE 39.9637% -83 - C2 -3A4O X:[20-206] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLGAGQFGEVWMGYY--N-NSTKVAVKTLKPGTMSV-----QAFLEEANLMKTLQHDKLVRLYAV-VTREEPIYIITEYMAKGSLLDFLKSD----EGG----KVLLPKLIDFSAQ-IAEGMAYIERK---NY--IHRDLRAANVLVSESLMCKIADFGLARV---------EGAKF---PIKWTAPE-AINFG----C----FT-IKSDVWSFGILLYEIVT----------------------------------------------------------------------------------------