@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : JAK3_HUMAN: (2013-07-21 )
MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Atome Classification :

(76 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530......-.540...-....550--.......560.......570.......580.......590..-.-....600.......610..-.....620.......630.......640.......650.......--660.......670.......680.......690....-...700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820....--...830.......840.-......850.....-.---.-860.........870.......880.......890.......900.......910......---.920.......930.......940.......950.......960.......970....-...980.......990.......1000......1010......1020......--1030......1040.....-.1050......1060......1070......1080......1090......1100......1110......1120.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRG-CRHEVVD-GEARKTE--VLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAG-D-STMVQEFVHLGAIDMYLRK-RGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREG--ADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECL-REAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMMGCERDVPALC-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS
7 PsiBlast_PDB 87.3799%-107 - C1 -4HVI A:[5-291] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q--------GPDQQRDFQREIQILKALHSDFIVKYRGVSY------LRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMM-----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSG-----------------------
2 PsiBlast_PDB 86.9799%-104 - C1 -3LXL A:[17-301] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMMG----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML--------------------------
6 PsiBlast_PDB 86.9399%-107 - C1 -4HVH A:[4-292] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSY------LRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMM-----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGS----------------------
5 PsiBlast_PDB 86.7899%-103 - C1 -4HVG A:[4-293] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSYGP----LRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMM-----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR---------------------
4 PsiBlast_PDB 86.6699%-105 - C1 -4HVD A:[5-291] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSY------LRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMM-----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSG-----------------------
1 PsiBlast_PDB 84.7699%-103 - C1 -3LXK A:[18-301] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIFEERHLKYIS--QLGKGNFGSVELCRYDP-LGDNTGALVAVKQL-Q---H-S--GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHR---ARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL-DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCS--PSAEFLRMM-----VPALS-RLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML--------------------------
9 PsiBlast_PDB 79.7861%-103 - C1 -4BBF JAK2_HUMAN A:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
21 PsiBlast_CBE 79.4361%-102 - C1 -4BBF D:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
8 PsiBlast_PDB 76.9161%-102 - C1 -4BBE JAK2_HUMAN A:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
23 PsiBlast_CBE 75.9761%-101 - C1 -4BBF JAK2_HUMAN B:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
24 PsiBlast_CBE 75.3061%-101 - C1 -4BBE D:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
22 PsiBlast_CBE 73.9661% -99 - C1 -4BBF JAK2_HUMAN C:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
26 PsiBlast_CBE 73.4961% -97 - C1 -4BBE JAK2_HUMAN B:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
10 PsiBlast_PDB 73.3561% -99 - C1 -3UGC A:[6-289] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTK--------------PGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
25 PsiBlast_CBE 73.1961% -96 - C1 -4BBE JAK2_HUMAN C:[5-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQFEERHLKFLQ--QLGKGNFGSVEMCRYDP-LQDNTGEVVAVKKL-Q---H-S--TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHK---ERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQ-DKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKS--PPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI--------------------------
18 PsiBlast_PDB 69.9550%-105 - C1 -3NYX A:[8-296] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TND--GEMVAVKAL-KA--D-C--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-EKSLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHSQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
28 PsiBlast_CBE 69.1551%-102 - C1 -4E20 A:[1-282] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPTVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-K---E-GC-GPQLRSGWQREIEILRTLYHEHIVKYKGCCED----SVQLVMEYVPLGSLRDYLPRHC---VGL--AQLLLFAQQICEGMAYLHAQHYIHRALAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSNQS--PHTKFTELIG----QMTVL-RLTELLERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPIL-----------------------------
20 PsiBlast_PDB 68.0850% -99 - C1 -3NZ0 A:[7-296] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPTVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-KA--D-C--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIG------TVL-RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
19 PsiBlast_PDB 67.8950%-104 - C1 -4GFO ? A:[9-296] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-----------------WKQEIDILRTLYHEHIIKYKGCCE------LQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHSQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
14 PsiBlast_PDB 67.5050% -91 - C1 -4GII ? A:[9-296] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-KA--D-A--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
16 PsiBlast_PDB 67.2550% -92 - C1 -4GJ3 ? A:[9-296] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-KA--D-A--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
15 PsiBlast_PDB 66.8450% -91 - C1 -4GJ2 ? A:[9-296] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-KA--D-A--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
12 PsiBlast_PDB 66.0456% -89 - C1 -4FVP A:[1-274] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFHKIRNEDLIFNESLGQGTFTKIFKG-VRREVGDYGQLHETE--VLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCG-DENILVQEFVKFGSLDTYLKK-NKNCINILWKLEVAKQLAAAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKAAELANLINNCMDYEPDHRPSFRAIIRDLNSLF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 66.0050% -90 - C1 -4GIH ? A:[9-296] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-KA--D-A--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYVPLGSLRDYLPRHS---IGL--AQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVL-RLTELLERGERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR---------------------
27 PsiBlast_CBE 65.3951% -96 - C1 -4E1Z A:[2-283] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPTVFHKRYLKKIR--DLGEGHFGKVSLYCYDP-TNDGTGEMVAVKAL-K---E-GC-GPQLRSGWQREIEILRTLYHEHIVKYKGCCED---KSVQLVMEYVPLGSLRDYLPRHC---VGL--AQLLLFAQQICEGMAYLHAQHYIHRALAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSNQS--PHTKFTELIGHTQGQMTVL-RLTELLERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPIL-----------------------------
130 HHSearch 62.0737% -95 - C1 -4FL3 KSYK_HUMAN A:[375-632] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--ELGSGNFGTVKKGYYQM-K--KVVKTVAVKIL-K---N-EANDPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR----HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA--------------PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY----------------RGMKGS-EVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD-----------------------
76 PsiBlast_CBE 59.5536%-103 - C1 -3POZ A:[11-269] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-----VKIPVAIKEL-------------ANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK---------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
86 PsiBlast_CBE 59.1836%-104 - C1 -1XKK A:[36-294] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-----VKIPVAIKEL-R---E------KANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK----------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
120 HHSearch 59.1437% -97 - C1 -4AOJ NTRK1_HUMAN A:[33-320] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVHHIKRRDIVLKW--ELGEGAFGKVFLAECHNLLP---KMLVAVKAL-K---E-A--SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRP--LLMVFEYMRHGDLNRFLRSHGPDPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFG------------------TMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPW----------------YQLSNT-EAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQA-----------------------
85 PsiBlast_CBE 58.8036%-103 - C1 -2RGP A:[5-263] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-----VKIPVAIKEL-R----------KANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEK----------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
41 PsiBlast_CBE 58.3937%-102 - C1 -4I24 EGFR_HUMAN A:[13-271] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-------------ANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL---------------VPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
68 PsiBlast_CBE 57.5636%-104 - C1 -3W33 A:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R----------KANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL--------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
40 PsiBlast_CBE 56.4437% -96 - C1 -4I24 B:[13-271] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLG-------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
32 PsiBlast_CBE 56.2838% -87 - C1 -3BCE C:[11-273] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETELKRVK--VLGSGAFGTVYKGIWVP-EGETVKIPVAIKIL-N---E-TT-GPKANVEFMDEALIMASMDHPHLVRLLGVCLSP---TIQLVTQLMPHGCLLEYVHEHK---DNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLE--DEKEYNA-DG-KMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPT----------REIP-------DLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF-----------------------------
69 PsiBlast_CBE 56.1936% -93 - C1 -3W32 A:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
30 PsiBlast_CBE 56.1837% -88 - C1 -2R4B B:[16-296] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAP-----NQAQL------RILKETELKRVK--VLGSGAFGTVYKGIWVP-EGETVKIPVAIKIL-------------ANVEFMDEALIMASMDHPHLVRLLGVCLSP---TIQLVTQLMPHGCLLEYVHEHK---DNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEG-DEKEYNA-DGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYD--GIP--------TREIP-------DLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF-----------------------------
29 PsiBlast_CBE 56.0044% -87 - C1 -3ZON A:[39-331] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV-----------ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL-AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLP-----LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP---QLATLTSQCLTYEPTQRPSFRTILRDLTRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91 PsiBlast_CBE 55.6236% -95 - C1 -3W2Q A:[15-273] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
57 PsiBlast_CBE 55.4436% -96 - C1 -3GT8 EGFR_HUMAN B:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKL-----------------PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFREL---------------------------------
42 PsiBlast_CBE 55.2737% -94 - C1 -2JIU EGFR_HUMAN A:[12-270] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
74 PsiBlast_CBE 55.2136% -96 - C1 -3UG2 A:[18-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLSS---GTVYKGLWIP-EGEKVKIPVAIKE-----------SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
70 PsiBlast_CBE 55.1836%-100 - C1 -3W2S A:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL--------------KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
35 PsiBlast_CBE 55.1038% -93 - C1 -3BBT ERBB4_HUMAN B:[11-273] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETELKRVK--VLGSGAFGTVYKGIWVP-EGETVKIPVAIKIL-N---E----GPKANVEFMDEALIMASMDHPHLVRLLGVCLSP---TIQLVTQLMPHGCLLEYVHEHK---DNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLL----------------PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPT----------REIP-------DLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF-----------------------------
71 PsiBlast_CBE 54.9836% -92 - C1 -2GS6 A:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-------T--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
73 PsiBlast_CBE 54.9136% -96 - C1 -3VJN A:[18-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLSS---GTVYKGLWIP-EGEKVKIPVAIKEL-----EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLIMQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------
31 PsiBlast_CBE 54.8137% -86 - C1 -2R4B ERBB4_HUMAN A:[16-296] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVEPLTPSGTAP-----NQAQL------RILKETELKRVK--VLGSGAFGTVYKGIWVP-EGETVKIPVAIKIL-N-----------ANVEFMDEALIMASMDHPHLVRLLGVCLSP---TIQLVTQLMPHGCLLEYVHEHK---DNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEG-DEKEYNA-DGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYD--GIP--------TREIP-------DLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF-----------------------------
55 PsiBlast_CBE 54.7636% -97 - C1 -3GT8 D:[14-272] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-R---EAT--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKL-----------------PIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFREL---------------------------------
87 PsiBlast_CBE 54.5936% -92 - C1 -4JRV ? A:[13-271] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKETEFKKIK--VLGSGAFGTVYKGLWIP-EGEKVKIPVAIKEL-------T--SPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLMPFGCLLDYVREHK---DNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA--EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYD---------------GIPA-S-EISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFREL---------------------------------