@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : KCC2D_HUMAN: (2013-07-21 )
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI

Atome Classification :

(56 SA) .........10........20........30...---.....40...--....---.50.-..----..----.-...----60........-70........80........90........100....----.----..110.......120......-.130.......140......-.150-.......160-........170...-....180.....------..190.......200.......210.....--..220.......230.......240.......250.......260-----.-----......270----.----...----.----..280.......290.........300------........310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKI---PTGQEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILESVNHCH-LNGIVHRDLKPENLLLASKS-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----A-----SEALKHPWI----C----QRS----T----VASMMHRQETVDC--LKKFNARRKLK-------GAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI
138 HHSearch 83.3489% -95 - C1 -3SOA KCC2A_HUMAN A:[7-444] -------TRFTEEYQLFEELGKG--SVVRRCVKV---LAGQEYAAMI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILEAVLHCH-QMGVVHRNLKPENLLLASKL-KGAA-VKLADFGLA--IEVEGEQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDLWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT-----A-----AEALKHPWI----S----HRS----T----VASCMHRQETVDC--LKKFNARRKLK-------GAILTVMLATRNFS-----------------------------VRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPS-------------------------
2 PsiBlast_PDB 80.0999%-124 - C1 -2WEL KCC2D_HUMAN A:[2-308] ---------MTDEYQLFEELGKGAFSVVRRCMKI---PTGQEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILESVNHCH-LNGIVHRDLKPENLLLASKS-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----A-----SEALKHPWI----C----QR------------SMMHRQETVDC--LKKFNARRKLK-------GAILTTMLATRNFSA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 79.7399%-114 - C1 -2VN9 KCC2D_HUMAN A:[2-301] ---------MTDEYQLFEELGKGAFSVVRRCMKI---PTGQEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILESVNHCH-LNGIVHRDLKPENLLLASKS-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----A-----SEALKHPWI----C----QRS----T----VASMMHRQETVDC--LKKFNARRKLK-------GAILTTML----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 77.2799%-114 - C1 -2VN9 KCC2D_HUMAN B:[2-301] ---------MTDEYQLFEELGKGAFSVVRRCMKI---PTGQEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILESVNHCH-LNGIVHRDLKPENLLLASKS-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----A-----SEALKHPWI----C----QRS----T----VASMMHRQETVDC--LKKFNARRKLK-------GAILTTML----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 76.7991%-115 - C1 -3BHH KCC2B_HUMAN A:[2-293] ---------MTDEYQLYEDIG----SVVRRCVKL---CTGHEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILEAVLHCH-QMGVVHRDLKPENLLLASKC-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----A-----HEALKHPWV----C----QRS----T----VASMMHRQETVEC--LKKFNARRKLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 76.2791%-114 - C1 -3BHH KCC2B_HUMAN B:[2-293] ---------MTDEYQLYEDIGK---SVVRRCVKL---CTGHEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIQQILEAVLHCH-QMGVVHRDLKPENLLLASKC-KGAA-VKLADFGLA--IEVQGDQQAWFGFA-GTPGYLSPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----A-----HEALKHPWV----C----QRS----T----VASMMHRQETVEC--LKKFNARRKLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 76.1691%-109 - C1 -2V7O KCC2G_HUMAN A:[25-321] -----TCTRFTDDYQLFEELGKG-FSVVRRCVKK---TPTQEYAAKI--INTK---KL-S-AR----DH----Q-KLE----REARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----Y----YSEADASHCIHQILESVNHIH-QHDIVHRDLKPENLLLASKC-KGAA-VKLADFGLA--IEVQGEQQAWFGFA-GTPGYLSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----A-----DQALKHPWV----C----QRS----T----VASMMHRQETVEC--LRKFNARRKLK-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
150 HHSearch 66.1648%-100 - C1 -3C0I CSKP_HUMAN A:[20-317] -------VLFEDVYELCEVIGKGPFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRA----DAGFVYSEAVASHYMRQILEALRYCH-DNNIIHRDVKPHCVLLASKE-NSAP-VKLGGFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT--K-ERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 PsiBlast_PDB 65.4749%-100 - C1 -3MFU CSKP_HUMAN A:[22-320] ---------FEDVYELCEVIGKGAFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPENVLLASKE-NSAP-VKLGDFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT---KERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKLK-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 65.1547%-103 - C1 -3C0H CSKP_HUMAN A:[22-318] ---------FEDVYELCEVIGKGPFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPHCVLLASKE-NSAP-VKLGGFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT--KE-RLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 64.9149%-103 - C1 -3MFS CSKP_HUMAN A:[22-320] ---------FEDVYELCEVIGKGAFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPENVLLASKE-NSAP-VKLGDFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT---KERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKLK-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 64.7449%-100 - C1 -3MFR CSKP_HUMAN A:[22-320] ---------FEDVYELCEVIGKGAFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPENVLLASKE-NSAP-VKLGDFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT---KERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKLK-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 63.4347%-104 - C1 -3C0H CSKP_HUMAN B:[22-318] ---------FEDVYELCEVIGKGPFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPHCVLLASKE-NSAP-VKLGGFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT--KE-RLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
140 HHSearch 62.9943%-112 * C1 *4FG7 KCC1A_HUMAN A:[13-277] ------AEDIRDIYDFRDVLGTGAFSEVILAEDK---RTQKLVAIKC--IA------------------------SME----NEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG----F----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLD-EDSK-IMISDFGLS--KMEDP-G---------TPGYVAPEVLA------QK--SKAVDCWSIGVIAYILLCGYPPFYDE--NDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFT-----C-----EQALQHPWI----A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114 PsiBlast_CBE 62.9141%-114 - C1 -2PHK PHKG1_RABIT A:[2-276] ---------FYENYEPKEILGRGVSSVVRRCIHK---PTCKEYAVKI--IDVTGGGSF-S-AE----EV----Q-ELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKV----T----LSEKETRKIMRALLEVICALH-KLNIVHRDLKPENILL---D-DDMN-IKLTDFGFS--CQLDPGEKLR-EVC-GTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWHR--KQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYT-----A-----EEALAHPFF----Q----Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113 PsiBlast_CBE 62.8540%-112 - C1 -1PHK PHKG1_RABIT A:[15-291] ---------FYENYEPKEILGRGVSSVVRRCIHK---PTCKEYAVKI--IDVTGGGSF-S-AE----EV----Q-ELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKV----T----LSEKETRKIMRALLEVICALH-KLNIVHRDLKPENILL---D-DDMN-IKLTDFGFS--CQLDPGEKLR-EVC-GTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWHR--KQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYT-----A-----EEALAHPFF---------QQY----V-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108 PsiBlast_CBE 62.1038%-105 - C1 -2CKE DAPK2_HUMAN A:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-ASRRGVSR----E-EIE----REVSILRQVL-HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----N----QQAMVRRESVVNLENFRKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 61.4047%-100 - C1 -3C0G CSKP_HUMAN A:[22-326] ---------FEDVYELCEVIGKGPFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPHCVLLASKE-NSAP-VKLGGFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT--KE-RLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKLK---------VLAAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104 PsiBlast_CBE 61.3440%-111 - C1 -1QL6 PHKG1_RABIT A:[15-291] ---------FYENYEPKEILGRGVSSVVRRCIHK---PTCKEYAVKI--IDVTGGGSF-S-AE----EV----Q-ELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKV----T----LSEKETRKIMRALLEVICALH-KLNIVHRDLKPENILL---D-DDMN-IKLTDFGFS--CQLDPGEKLR-SVC-GTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWHR--KQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYT-----A-----EEALAHPFF---------QQY----V-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106 PsiBlast_CBE 61.2338%-102 - C1 -2CKE DAPK2_HUMAN C:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-ASRRGVSR----E-EIE----REVSILRQVL-HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----N----QQAMVRRESVVNLENFRKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94 PsiBlast_CBE 61.0240%-113 - C1 -2Y7J PHKG2_HUMAN C:[92-363] ---------FYQKYDPKDVIGRGVSSVVRRCVHR---ATGHEFAVKIMEVTAE---RL-S-PE----QL----E-EVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV----A----LSEKETRSIMRSLLEAVSFLH-ANNIVHRDLKPENILL---D-DNMQ-IRLSDFGFS--CHLEPGEKLR-ELC-GTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHR--RQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLT-----A-----EQALQHPFF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105 PsiBlast_CBE 60.1438%-103 - C1 -2CKE DAPK2_HUMAN D:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-ASRRGVSR----E-EIE----REVSILRQVL-HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----N----QQAMVRRESVVNLENFRKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 59.8840%-115 - C1 -2Y7J PHKG2_HUMAN A:[92-363] ---------FYQKYDPKDVIGRGVSSVVRRCVHR---ATGHEFAVKIMEVTAE---RL-S-PE----QL----E-EVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV----A----LSEKETRSIMRSLLEAVSFLH-ANNIVHRDLKPENILL---D-DNMQ-IRLSDFGFS--CHLEPGEKLR-ELC-GTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHR--RQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLT-----A-----EQALQHPFF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 59.6847% -99 - C1 -3C0G CSKP_HUMAN B:[22-326] ---------FEDVYELCEVIGKGPFSVVRRCINR---ETGQQFAVKI--VDVA---KF-T-SSPGL-ST----E-DLK----REASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFV----YSEAVASHYMRQILEALRYCH-DNNIIHRDVKPHCVLLASKE-NSAP-VKLGGFGVA--IQLGESGLVAGGRV-GTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGCLPFYGT--KE-RLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----V-----YEALNHPWL----K----ERD----R----YAYKIHLPETVEQ--LRKFNARRKLK-------GAVLAAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 59.6440%-113 - C1 -3LIJ ? A:[26-335] MFITSKKGHLSEMYQRVKKLGS---GEVLLCRDK---VTHVERAIKI--IRK----------S----SN----S-KLL----EEVAVLKLLD-HPNIMKLYDFFEDKRNYYLVMECYKGGELFDEIIHRM----K----FNEVDAAVIIKQVLSGVTYLH-KHNIVHRDLKPENLLLESKE-KDAL-IKIVDFGLS--A-VFENQKKMKERL-GTAYYIAPEVLR------K-KYDEKCDVWSIGVILFILLAGYPPFGGQ--TDQEILRKVEKGKYTFDSPEWKNVSEGAKDLIKQMLQFDSQRRIS-----A-----QQALEHPWIKEMCS----KKE----S-------LPSLANAIEN--MRKFQNSQKLA-------QAALLYM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84 PsiBlast_CBE 59.4741%-107 - C1 -4FG8 KCC1A_HUMAN A:[18-299] -----------DIYDFRDVLGTGAFSEVILAEDK---RTQKLVAIKC--IAKE-----------------------------NEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG----F----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLD-EDSK-IMISDF---------------------TPGYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDE--NDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFT-----C-----EQALQHPWI----A----GDT----A----LDKNIH-QSVSEQ--IKKNFA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107 PsiBlast_CBE 59.2938%-107 - C1 -2CKE DAPK2_HUMAN B:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-ASRRGVSR----E-EIE----REVSILRQVL-HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----N----QQAMVRRESVVNLENFRKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 PsiBlast_CBE 59.1540%-115 - C1 -2Y7J PHKG2_HUMAN D:[92-363] ---------FYQKYDPKDVIGRGVSSVVRRCVHR---ATGHEFAVKIMEV------RL-S-PE----QL----E-EVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV----A----LSEKETRSIMRSLLEAVSFLH-ANNIVHRDLKPENILL---D-DNMQ-IRLSDFGFS--CHLEPGEKLR-ELC-GTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHR--RQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLT-----A-----EQALQHPFF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 58.6843%-105 - C1 -3MA6 ? A:[30-291] ---------FSDRYKGQRVLGKGSFGEVILCKDK---ITGQECAVKV--ISKR---QV-K-QKT---DK----E-SLL----REVQLLKQLD-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRK----R----FSEVDAARIIRQVLSGITYMH-KNKIVHRDLKPENLLLESKS-KDAN-IRIIDFGLS--THFE-SKKMKDKI--GTAYYIAPEVLH-------GTYDEKCDVWSTGVILYILLSGCPPFNGA--NEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRIS-----A-----RDALDHEWI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89 PsiBlast_CBE 58.5037%-101 - C1 -2YAA DAPK2_MOUSE B:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-AS----RRGVCRE-EIE----REVSILRQVL-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----T----QQAMVRRESVVNLENFKKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90 PsiBlast_CBE 58.2637%-103 - C1 -2YAA DAPK2_MOUSE A:[12-302] -----------DFYDIGEELGSGQFAIVKKCREK---STGLEYAAKF--IKKR---QS-R-AS----RRGVCRE-EIE----REVSILRQVL-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKE----S----LSEEEATSFIKQILDGVNYLH-TKKIAHFDLKPENIMLLDKN-IPIPHIKLIDFGLA--HEIE-DGVEFKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLT-----I-----QEALRHPWI----T----PVD----T----QQAMVRRESVVNLENFKKQYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 57.7841%-105 - C1 -4FG8 KCC1A_HUMAN B:[18-299] -----------DIYDFRDVLGTGAFSEVILAEDK---RTQKLVAIKC--IAK------------------------------NEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG----F----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLD-EDSK-IMISDFG----------GSVLSTAC-GTPGYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDE--NDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFT-----C-----EQALQHPWI----A----GDT----A----LDKNIH-QSVSEQ--IKKNFA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78 PsiBlast_CBE 57.5340%-101 - C1 -3HZT ? A:[3-317] ----------SDRYQRVKKLGSGAYGEVLLCKDK---LTGAERAIKI--IKKS---SV-T-TT----SN----SGALL----DEVAVLKQLD-HPNIMKLYEFFEDKRNYYLVMEVYRGGELFDEIILRQ----K----FSEVDAAVIMKQVLSGTTYLH-KHNIVHRDLKPENLLLESKS-RDAL-IKIVDFGLSAHFEVG------------TAYYIAPEVLR------K-KYDEKCDVWSCGVILYILLCGYPPFGGQ--TDQEILKRVEKGKFSFDPPDWTQVSDEAKQLVKLMLTYEPSKRIS-----A-----EEALNHPWI----VKFCSQ------------VGKHALTGALGN--MKKFQSSQKLAQAAMLFMGSKLTTLEETKELT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 56.8845%-106 - C1 -2JAM KCC1G_HUMAN A:[6-265] --------NIRKTFIFMEVLGSGAFSEVFLVKQR---LTGKLFALKC--I--K---KS-----------------SLE----NEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG----V----YTEKDASLVIQQVLSAVKYLH-ENGIVHRDLKPENLLYLTPE-ENSK-IMITDFGLS-----KMEQNGIMSTACGTPGYVAPEVLA------QKPYSKAVDCWSIGVITYILLCGYPPFYEE--TESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYT-----C-----EKALSHPWI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79 PsiBlast_CBE 56.5243%-106 - C1 -3MA6 ? B:[30-291] ---------FSDRYKGQRVLGKGSFGEVILCKDK---ITGQECAVKV--ISKR---QV-K-Q-T---DK----E-SLL----REVQLLKQLD-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRK----R----FSEVDAARIIRQVLSGITYMH-KNKIVHRDLKPENLLLESKS-KDAN-IRIIDFGLS--THFEASKKMKDKI--GTAYYIAPEVLH-------GTYDEKCDVWSTGVILYILLSGCPPFNGA--NEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRIS-----A-----RDALDHEWI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81 PsiBlast_CBE 56.3445%-105 - C1 -2JAM KCC1G_HUMAN B:[5-265] -------TNIRKTFIFMEVLGSGAFSEVFLVKQR---LTGKLFALKC--I--K---KS-----------------SLE----NEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG----V----YTEKDASLVIQQVLSAVKYLH-ENGIVHRDLKPENLLYLTPE-ENSK-IMITDFGLS-----KMEQNGIMSTACGTPGYVAPEVLA------QKPYSKAVDCWSIGVITYILLCGYPPFYEE--TESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYT-----C-----EKALSHPWI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 55.7243%-102 - C1 -2W4O KCC4_HUMAN A:[51-346] ---------LSDFFEVESELGRGATSIVYRCKQK---GTQKPYALKV--LK--------K------------------------IGVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKG----Y----YSERDAADAVKQILEAVAYLH-ENGIVHRDLKPENLLYATPA-PDAP-LKIADF--------------------GTPGYCAPEILR------GCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLT-----T-----FQALQHPWV----T----GKA----------ANFVHMDTAQKK--LQEFNARRKLK-------AAVKAVVASS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115 PsiBlast_CBE 55.5235%-100 - C1 -2W4K DAPK1_HUMAN A:[11-302] -----------DYYDTGEELGSGQFAVVKKCREK---STGLQYAAKF--IKKR---RTKS-SRRGV-SR----E-DIE----REVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE----S----LTEEEATEFLKQILNGVYYLH-SLQIAHFDLKPENIMLLDRNVPKPR-IKIIDFGLA--HKIDFGNE-FKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMT-----I-----QDSLQHPWI----K----PKD----T----QQALSRKASAVNMEKFKKFAAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
153 HHSearch 55.3141% -94 - C1 -3MWU ? A:[18-324] -------GTFAERYNIVCMLGKGSFGEVLKCKDR---ITQQEYAVKV--INKA---SA-K-NK----DT----S-TIL----REVELLKKLD-HPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRK----R----FSEHDAARIIKQVFSGITYMH-KHNIVHRDLKPENILLESKE-KDCD-IKIIDFGLS--TCFQQN-----DRI-GTAYYIAPEVLR------G-TYDEKCDVWSAGVILYILLSGTPPFYGK--NEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRIT-----A-----TQCLEHPWI----Q----KYS----SETPTISDLPSLESAMTN--IRQFQAEKKLA-------QAALLYMASKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 54.7338% -90 - C1 -3UPX ? A:[24-365] ---------FSDRYKGQRVLGKGSFGEVILCKDK---ITGQECAVKV--ISKR---QV-K-QKT---DK----E-SLL----REVQLLKQLD-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRK----R----FSEVDAARIIRQVLSGITYMH-KNKIVHRDLKPENLLLESKS-KDAN-IRIIDFGLS--THFEASKKMKDKI--GTAYYIAPEVLH-------GTYDEKCDVWSTGVILYILLSGCPPFNGA--NEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRIS-----A-----RDALDHEWI----------------------QTYTK------V--PSLDNAILNIR-------QFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELM---------------------------------------------------------------------------------------------------------------------------------------------
122 PsiBlast_CBE 54.5234%-101 - C1 -2Y0A DAPK1_HUMAN A:[11-293] -----------DYYDTGEELGSGQFAVVKKCREK---STGLQYAAKF--IKKR---RTKS-SRRGV-SR----E-DIE----REVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE----S----LTEEEATEFLKQILNGVYYLH-SLQIAHFDLKPENIMLLDRNVPKPR-IKIIDFGLA--HKIDFGNE-FKNIF-GTPEFVAPEIVN------YEPLGLEADMWSIGVITYILLSGASPFLGD--TKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMT-----I-----QDSLQHPWI----K----PKD----T----QQALSRKASAVNM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86 PsiBlast_CBE 54.3441% -99 - C1 -4FG9 KCC1A_HUMAN A:[18-313] -----------DIYDFRDVLGTGAFSEVILAEDK---RTQKLVAIKC--IAKE------------------------E----NEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG----F----YTERDASRLIFQVLDAVKYLH-DLGIVHRDLKPENLLYYSLD-EDSK-IMISDF----------------------PGYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDE--NDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFT-----C-----EQALQHPWI----A----GDT----A----LDKNIH-QSVSEQ--IKKNFAKSKWK-------QAFNATAVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
159 HHSearch 53.6040% -99 - C1 -3NYV ? A:[21-326] ------TAIFSDRYKGQRVLGKGSFGEVILCKDK---ITGQECAVKV--ISKR---QV-KQKT----DK----E-SLL----REVQLLKQLD-HPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRK----R----FSEVDAARIIRQVLSGITYMH-KNKIVHRDLKPENLLLESKS-KDAN-IRIIDFGLS--THFEASK-KMKDKI-GTAYYIAPEVLH------G-TYDEKCDVWSTGVILYILLSGCPPFNGA--NEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRIS-----A-----RDALDHEWI----Q----TYT----K------DVPSLDNAILN--IRQFQGTQKLA-------QAALLYMGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 53.4740% -97 - C1 -3IGO ? A:[20-320] ---------FAERYNIVCMLGKGSFGEVLKCKDR---ITQQEYAVKV--INKA---SA-K-NK-----T----S-TIL----REVELLKKLD-HPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRK----R----FSEHDAARIIKQVFSGITYMH-KHNIVHRDLKPENILLESKE-KDCD-IKIIDFGLS--TCFQQNT---------TAYYIAPEVLR-------GTYDEKCDVWSAGVILYILLSGTPPFYGK--NEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRIT-----A-----TQCLEHPWI----Q----KYSSETPT----ISDLPSLESAMTN--IRQFQAEKKLA-------QAALLYM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------