@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : KKCC2_HUMAN: (2013-07-22 )
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQRRQPPGHRPAPRGGGGSALVRGSPCVESCWAPAPGSPARMHPLRPEEAMEPE
Atome Classification :
(29 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160-.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270....-.-..280........290.......300....-...310.......320--........330.......340.......350.......360.......370.......380.......390...-....400..--.....--410--.......420.......430...-----.-----...440....-----...450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQL-NQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVM-E-VPT-LKPLSEDQARFYFQDLIKGIEYLHYQ-KIIHRDIKPSNLLVG---EDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERI-MCLHSKIKS--QALEF--PDQ--PDIAEDLKDLITRMLDKNPESRI-----V-----VPEIKLHPWV-----TRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQRRQPPGHRPAPRGGGGSALVRGSPCVESCWAPAPGSPARMHPLRPEEAMEPE
1
PsiBlast_PDB
86.96
100%
-116
- C1 -
2ZV2
1
KKCC2_HUMAN
A:
[10-298]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
-
N
Q
Y
T
L
K
D
E
I
G
K
--
Y
G
V
V
K
L
A
Y
N
E
N
D
N
T
Y
Y
A
M
K
V
L
S
K
K
-------------------------------
E
Q
V
Y
Q
E
I
A
I
L
K
K
L
D
H
P
N
V
V
K
L
V
E
V
L
D
D
P
N
E
D
H
L
Y
M
V
F
E
L
V
N
Q
G
P
V
M
-
E
-
V
P
T
-
L
K
P
L
S
E
D
Q
A
R
F
Y
F
Q
D
L
I
K
G
I
E
Y
L
H
Y
Q
-
K
I
I
H
R
D
I
K
P
S
N
L
L
V
G
---
E
D
G
H
I
K
I
A
D
F
G
V
S
N
E
F
K
G
S
D
A
L
L
S
N
T
V
G
T
P
A
F
M
A
P
E
S
L
S
E
T
R
K
I
F
S
G
K
A
L
D
V
W
A
M
G
V
T
L
Y
C
F
V
F
G
Q
C
P
F
M
D
E
R
I
-
M
C
L
H
S
K
I
K
S
--
Q
A
L
E
F
--
P
D
Q
--
P
D
I
A
E
D
L
K
D
L
I
T
R
M
L
D
K
N
P
E
S
R
I
-----
V
-----
V
P
E
I
K
L
H
P
W
V
-----
T
R
--------------------------------------------------------------------------------------------------------------------------------------------
96
HHSearch
64.48
31%
-104
- C1 -
2Y94
1
AAPK1_RAT
A:
[9-281]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
H
D
G
R
V
K
I
-
G
H
Y
I
L
G
D
T
L
G
V
G
T
F
G
K
V
K
V
G
K
H
E
L
T
G
H
K
V
A
V
K
I
L
N
R
Q
K
I
R
S
L
-----------------------
D
V
V
G
K
I
R
R
E
I
Q
N
L
K
L
F
R
H
P
H
I
I
K
L
Y
Q
V
I
S
--
T
P
S
D
I
F
M
V
M
E
Y
V
S
G
G
E
L
F
-
D
-
Y
I
C
K
N
G
R
L
D
E
K
E
S
R
R
L
F
Q
Q
I
L
S
G
V
D
Y
C
H
R
H
-
M
V
V
H
R
D
L
K
P
E
N
V
L
L
D
---
A
H
M
N
A
K
I
A
D
F
G
L
S
N
M
M
S
D
-
G
E
F
L
R
T
S
C
G
S
P
N
Y
A
A
P
E
V
I
S
G
--
R
L
Y
A
G
P
E
V
D
I
W
S
S
G
V
I
L
Y
A
L
L
C
G
T
L
P
F
D
D
D
H
V
-
P
T
L
F
K
K
I
C
D
--
G
I
F
Y
T
--
P
Q
----
Y
L
N
P
S
V
I
S
L
L
K
H
M
L
Q
V
D
P
M
K
R
A
-----
T
-----
I
K
D
I
R
E
H
E
W
F
-----
K
Q
D
L
P
K
Y
L
F
P
E
-----------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.78
32%
-99
- C1 -
2VN9
2
KCC2D_HUMAN
A:
[4-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
T
K
K
L
S
A
R
D
H
------------------------
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
-
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
SKS
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
R
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
S
E
A
L
K
H
P
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
63.62
32%
-107
- C1 -
4GV1
5
AKT1_HUMAN
A:
[3-270]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
V
T
M
-
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
-----------------------
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
--
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
-
F
-
H
L
S
R
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
---
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
--
D
N
D
Y
-
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
Y
N
Q
D
H
-
E
K
L
F
E
L
I
L
M
--
E
E
I
R
F
--
P
R
----
T
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
-----
G
GGS
E
D
A
K
E
I
M
Q
H
R
F
F
-----
A
G
--------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
61.85
31%
-99
- C1 -
2V7O
3
KCC2G_HUMAN
A:
[23-291]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
T
C
T
R
F
T
D
D
Y
Q
L
F
E
E
L
G
K
G
-
F
S
V
V
R
R
C
V
K
K
T
P
T
Q
E
Y
A
A
K
I
I
N
T
K
K
L
S
A
R
D
H
------------------------
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
H
Q
I
L
E
S
V
N
H
I
H
Q
H
-
D
I
V
H
R
D
L
K
P
E
N
L
L
L
A
SKC
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
E
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
D
P
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
K
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
P
S
P
E
W
--
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
D
Q
A
L
K
H
P
W
V
---------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
61.50
31%
-103
- C1 -
2F7Z
1
KAPCA_BOVIN
E:
[36-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
H
L
-
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
-----------------------
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
--
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
-
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
-
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
---
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
---
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
---
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
-
I
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
--
P
S
H
----
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
GNLKN
G
-----
V
N
D
I
K
N
H
K
W
F
-----
A
---------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
61.20
31%
-102
- C1 -
2OJF
1
KAPCA_BOVIN
E:
[36-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
H
L
-
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
-----------------------
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
--
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
-
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
-
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
---
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
---
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
---
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
-
I
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
--
P
S
H
----
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
GNLKN
G
-----
V
N
D
I
K
N
H
K
W
F
-----
A
---------------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
60.89
31%
-101
- C1 -
2OH0
1
KAPCA_BOVIN
E:
[36-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
H
L
-
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
-----------------------
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
--
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
-
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
-
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
---
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
---
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
---
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
-
I
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
--
P
S
H
----
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
GNLKN
G
-----
V
N
D
I
K
N
H
K
W
F
-----
A
---------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.62
32%
-101
- C1 -
2WEL
7
KCC2D_HUMAN
A:
[4-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
T
K
K
L
S
A
R
D
H
------------------------
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
-
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
SKS
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
R
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
S
E
A
L
K
H
P
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
60.37
31%
-100
- C1 -
2F7X
1
KAPCA_BOVIN
E:
[36-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
H
L
-
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
-----------------------
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
--
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
-
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
-
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
---
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
---
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
---
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
-
I
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
--
P
S
H
----
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
GNLKN
G
-----
V
N
D
I
K
N
H
K
W
F
-----
A
---------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
59.86
32%
-98
- C1 -
2VN9
1
KCC2D_HUMAN
B:
[4-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
T
K
K
L
S
A
R
D
H
------------------------
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
-
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
SKS
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
R
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
S
E
A
L
K
H
P
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
59.58
31%
-104
- C1 -
2F7E
1
KAPCA_BOVIN
E:
[36-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
H
L
-
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
-----------------------
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
--
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
-
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
-
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
---
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
---
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
---
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
-
I
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
--
P
S
H
----
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
GNLKN
G
-----
V
N
D
I
K
N
H
K
W
F
-----
A
---------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
57.70
31%
-97
- C1 -
3SOA
1
KCC2A_HUMAN
A:
[12-272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
Q
L
F
E
E
L
G
K
G
--
S
V
V
R
R
C
V
K
V
L
A
G
Q
E
Y
A
A
M
I
I
N
T
K
K
L
S
A
R
D
H
------------------------
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
--
E
G
H
H
Y
L
I
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
-
G
V
V
H
R
N
L
K
P
E
N
L
L
L
A
SKL
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
E
G
E
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
D
P
Y
G
K
P
V
D
L
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
R
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
S
K
R
I
-----
T
-----
A
A
E
A
L
K
H
P
W
I
-----
S
---------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
53.79
31%
-99
- C1 -
3BHH
1
KCC2B_HUMAN
B:
[4-266]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
Q
L
Y
E
D
I
G
K
---
S
V
V
R
R
C
V
K
L
C
T
G
H
E
Y
A
A
K
I
I
N
T
K
K
L
------
S
A
R
D
H
Q
K
L
E
R
E
A
R
------------------
I
C
R
L
L
K
H
S
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
-
G
V
V
H
R
D
L
K
P
E
N
L
L
L
A
SKC
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
E
A
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
K
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
H
E
A
L
K
H
P
W
V
-----
C
Q
--------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
53.53
31%
-97
- C1 -
3BHH
1
KCC2B_HUMAN
A:
[4-266]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
Q
L
Y
E
D
I
G
----
S
V
V
R
R
C
V
K
L
C
T
G
H
E
Y
A
A
K
I
I
N
T
K
K
L
------
S
A
R
D
H
Q
K
L
E
R
E
A
R
------------------
I
C
R
L
L
K
H
S
N
I
V
R
L
H
D
S
I
S
E
--
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
-
E
D
I
V
A
-
R
E
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
-
G
V
V
H
R
D
L
K
P
E
N
L
L
L
A
SKC
K
G
A
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
---
R
K
E
A
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
D
Q
-
H
K
L
Y
Q
Q
I
K
A
--
G
A
Y
D
F
PS
P
E
W
--
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
-----
T
-----
A
H
E
A
L
K
H
P
W
V
-----
C
Q
--------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
53.02
31%
-97
- C1 -
2CN8
1
CHK2_HUMAN
A:
[16-301]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
----
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
---------------------------------
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
--
T
S
L
M
R
T
L
C
--
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
---
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
----------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
52.69
31%
-99
- C1 -
4BDD
3
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
------
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
---------------------------------
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
--
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
52.57
31%
-95
- C1 -
2WTI
3
CHK2_HUMAN
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
----
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
------------------------------
P
A
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
-
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
52.38
31%
-92
- C1 -
2YCR
1
CHK2_HUMAN
A:
[10-300]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
---
G
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
---------------------------------
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
G
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
-------------
L
Q
D
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
K
----------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
52.10
31%
-94
- C1 -
3MWU
1
?
A:
[30-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
K
A
S
------------------------
A
K
N
K
D
T
S
T
I
L
R
E
V
E
L
L
K
K
L
D
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
--
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
-
I
I
K
-
R
K
R
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
-
N
I
V
H
R
D
L
K
P
E
N
I
L
L
E
SKE
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
-
Q
N
----
D
R
I
G
T
A
Y
Y
I
A
P
E
V
L
---
R
G
T
Y
D
E
K
C
-
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
-
Y
D
I
L
K
R
V
E
T
GK
Y
A
F
D
L
--
P
Q
W
--
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
-----
T
-----
A
T
Q
C
L
E
H
P
W
I
-----
Q
K
Y
S
S
E
T
---------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
51.76
31%
-95
- C1 -
3IGO
8
?
A:
[30-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
K
A
S
------------------------
A
K
N
K
-
T
S
T
I
L
R
E
V
E
L
L
K
K
L
D
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
--
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
-
I
I
K
-
R
K
R
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
-
N
I
V
H
R
D
L
K
P
E
N
I
L
L
E
SKE
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
-
Q
N
T
-------
T
A
Y
Y
I
A
P
E
V
L
---
R
G
T
Y
D
E
K
C
-
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
-
Y
D
I
L
K
R
V
E
T
GK
Y
A
F
D
L
--
P
Q
W
--
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
-----
T
-----
A
T
Q
C
L
E
H
P
W
I
-----
Q
K
Y
S
S
E
T
---------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
51.28
31%
-92
- C1 -
2XM9
1
CHK2_HUMAN
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
---
G
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
------------------------------
P
A
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
G
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
51.27
31%
-96
- C1 -
4BDK
4
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
----
G
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
-------------------------------
A
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
G
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
51.05
31%
-100
- C1 -
4BDB
10
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
------
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
--------------------------------
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
-
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
50.04
31%
-97
- C1 -
3NCG
1
?
A:
[30-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
K
A
S
------------------------
A
K
N
K
D
T
S
T
I
L
R
E
V
E
L
L
K
K
L
D
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
--
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
-
I
I
K
-
R
K
R
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
-
N
I
V
H
R
D
L
K
P
E
N
I
L
L
E
SKE
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
-
Q
N
T
-----
I
G
T
A
Y
Y
I
A
P
E
V
L
---
R
G
T
Y
D
E
K
C
-
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
-
Y
D
I
L
K
R
V
E
T
GK
Y
A
F
D
L
--
P
Q
W
--
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
-----
T
-----
A
T
Q
C
L
E
H
P
W
I
-----
Q
K
Y
S
S
E
T
---------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
49.40
31%
-98
- C1 -
4BDA
8
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
----
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
---------------------------------
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
-
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
49.08
31%
-96
- C1 -
4BDE
5
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
------
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
-------------------------------
A
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
--
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
49.01
31%
-95
- C1 -
2WTC
1
CHK2_HUMAN
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
G
S
----
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
------------------------------
P
A
L
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
--
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
V
W
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
48.23
31%
-99
- C1 -
4BDH
4
?
A:
[16-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
Y
I
M
S
K
T
L
------
E
V
K
L
A
F
E
R
K
T
C
K
K
V
A
I
K
I
I
S
K
---------------------------------
N
V
E
T
E
I
E
I
L
K
K
L
N
H
P
C
I
I
K
I
K
N
F
F
D
--
A
E
D
Y
-
Y
I
V
L
E
L
M
E
G
G
E
L
F
-
D
K
V
V
G
-
N
K
R
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
N
-
G
I
I
H
R
D
L
K
P
E
N
V
L
L
S
SQE
E
D
C
L
I
K
I
T
D
F
G
H
S
-
K
I
L
G
E
T
S
L
M
R
T
L
C
G
T
P
T
Y
L
A
P
E
V
L
V
S
V
G
T
A
G
Y
N
R
A
V
D
C
W
S
L
G
V
I
L
F
I
C
L
S
G
Y
P
P
F
S
E
H
R
T
Q
V
S
L
K
D
Q
I
T
S
--
G
K
Y
N
F
--
I
P
E
VW
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
-----
T
E
E
A
L
R
H
P
W
L
QD
E
D
M
K
R
K
F
Q
D
L
L
S
E
E
N
E
S
T
A
L
P
Q
V
--------------------------------------------------------------------------------------------------------------------------