@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : KPCD3_HUMAN: (2013-07-22 )
MSANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHESDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP

Atome Classification :

(43 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580---.........590.......600.......--610---..-....----.----620.......630.......640.......650.-..-.-.-..660.........670........680.......690.-......700.......710........720..-..-...730-.......740......-.750-.........760.......770....--.--.---.--780-.--.......-------------------.790---..----...----..800.......810.......820-----.......830..-----.....-----840.......850.......860.......870.......880.......890
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADE-----VLGSGQFGIVYGGKHRKTGRDVAIKVIDK--MRF---PT-KQES----Q----LRNEVAILQNLHHPGIVNLECMFETPERVFVVME-KL-H-G-DML--EMILSSEKSRL-PERITKFMVTQILVALRNLHFK-NIVHCDLKPENVLLASAE-PFPQVKLCDFGFA-RI-IGEKSF-RRSVVGTPAYLAPEVL-RS---KGYNRSLDMWSVGVIIYVSLSGTFPF--N--E---D--E---D--INDQIQN-------------------AAFM---YP----PNP----WREISGEAIDLINNLLQVKMRKRYS-----VDKSLSHPWLQD-----YQTWL-----DLREFETRIGERYITHESDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP
33 PsiBlast_CBE 70.2734%-107 - C1 -3MFR CSKP_HUMAN A:[19-315] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVLFEDVYELC--E-----VIGKGAFSVVRRCINRETGQQFAVKIVDV--AKFTSSPG-LSTE----D----LKREASICHMLKHPHIVELLETYSSDGMLYMVFE-FM-D-G-ADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDN-NIIHRDVKPENVLLASKE-NSAPVKLGDFGVA-IQ-LGESGLVAGGRVGTPHFMAPEVV-KR---EPYGKPVDVWGCGVILFILLSGCLPFY-G--T---K--E---R--LFEGIIK-------------------GKYK---MN----PRQ----WSHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNAR-------------------------------------------
32 PsiBlast_CBE 70.0034%-107 - C1 -3MFS CSKP_HUMAN A:[18-315] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDVLFEDVYELC--E-----VIGKGAFSVVRRCINRETGQQFAVKIVDV--AKFTSSPG-LSTE----D----LKREASICHMLKHPHIVELLETYSSDGMLYMVFE-FM-D-G-ADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDN-NIIHRDVKPENVLLASKE-NSAPVKLGDFGVA-IQ-LGESGLVAGGRVGTPHFMAPEVV-KR---EPYGKPVDVWGCGVILFILLSGCLPFY-G--T---K--E---R--LFEGIIK-------------------GKYK---MN----PRQ----WSHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNAR-------------------------------------------
31 PsiBlast_CBE 68.8334%-103 - C1 -3MFU CSKP_HUMAN A:[19-315] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVLFEDVYELC--E-----VIGKGAFSVVRRCINRETGQQFAVKIVDV--AKFTSSPG-LSTE----D----LKREASICHMLKHPHIVELLETYSSDGMLYMVFE-FM-D-G-ADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDN-NIIHRDVKPENVLLASKE-NSAPVKLGDFGVA-IQ-LGESGLVAGGRVGTPHFMAPEVV-KR---EPYGKPVDVWGCGVILFILLSGCLPFY-G--T---K--E---R--LFEGIIK-------------------GKYK---MN----PRQ----WSHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNAR-------------------------------------------
47 PsiBlast_CBE 66.5033%-104 - C1 -3C0I CSKP_HUMAN A:[20-315] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLFEDVYELC--E-----VIGKGPFSVVRRCINRETGQQFAVKIVDV--AKFTSSPG-LSTE----D----LKREASICHMLKHPHIVELLETYSSDGMLYMVFE-FM-D-G-ADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDN-NIIHRDVKPHCVLLASKE-NSAPVKLGGFGVA-IQ-LGESGLVAGGRVGTPHFMAPEVV-KR---EPYGKPVDVWGCGVILFILLSGCLPFY-G--T---K--E---R--LFEGIIK-------------------GKYK---MN----PRQ----WSHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNAR-------------------------------------------
116 HHSearch 66.1135%-112 * C1 *4FG7 KCC1A_HUMAN A:[9-277] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RWKQAEDIRDIYDF--RD-----VLGTGAFSEVILAEDKRTQKLVAIKCIA--------------------S----MENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQ-LV-SGG-ELF--DRIV--EKGFY-TERDASRLIFQVLDAVKYLHDL-GIVHRDLKPENLLYYSLD-EDSKIMISDFGLS-KM-EDPG---------TPGYVAPEVL-AQ---K--SKAVDCWSIGVIAYILLCGYPPF--Y--DEN-D--A---K--LFEQILK-------------------AEYE---FD----SPY----WDDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWIA-------------------------------------------------------------------
136 HHSearch 65.9635%-104 - C1 -3Q5I ? A:[21-309] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------INPGMYVRKKEGKIGESYFK--VR-----KLGS--YGEVLLCKEKNGHSEKAIKVIKK-----------KFHE----E----IYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTE-FY-E-GGELF--EQIIN--RHKF-DECDAANIMKQILSGICYLHKH-NIVHRDIKPENILLENKN-SLLNIKIVDFGLS-SF-FSKDYK-LRDRLGTAYYIAPEVL-KK----KYNEKCDVWSCGVIMYILLCGYPPF--G--GQN-D--Q---D--IIKKVEK-------------------GKYY---FD----FND----WKNISDEAKELIKLMLTYDYNKRCT-----AEEALNSRWIKK-----YA-----------------------------------------------------------
57 PsiBlast_CBE 65.7935%-107 - C1 -3HX4 ? A:[47-312] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISK-----------DKES----L----LR-EVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYT-G-G-ELF--DEIIS--RKRF-SEVDAARIIRQVLSGITYMHKN-KIVHRDLKPENLLLESKS-KDANIRIIDFGLS-TH-FEASKK-MKDKIGTAYYIAPEVL-HG---T-YDEKCDVWSTGVILYILLSGCPPF--NGAN---E--Y---D--ILKKVEK-------------------GKYT---FE----LPQ----WKKVSESAKDLIRKMLTYVPSMRIS-----ARDALDHEWIQT-----Y------------------------------------------------------------
54 PsiBlast_CBE 65.3034% -96 - C1 -2XUU DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPAFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
20 PsiBlast_PDB 64.8434%-118 - C1 -4FG8 KCC1A_HUMAN A:[10-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKQAEDIRDIYD-FRD------VLGTGAFSEVILAEDKRTQKLVAIKCIAK--E-----------------------NEIAVLHKIKHPNIVALDDIYESGGHLYLIMQ-LV-S-GGELF--DRIV--EKGFY-TERDASRLIFQVLDAVKYLHDL-GIVHRDLKPENLLYYSLD-EDSKIMISDF--------------------TPGYVAPEVL-AQ---KPYSKAVDCWSIGVIAYILLCGYPPF--Y--D---E--N---DAKLFEQILK-------------------AEYE---FD----SPY----WDDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI--------------------------------------------------------------------
94 PsiBlast_CBE 64.6933% -94 - C1 -2W4J DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
89 PsiBlast_CBE 64.6133% -95 - C1 -2W4K DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
88 PsiBlast_CBE 64.5033% -99 - C1 -2YAK DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
95 PsiBlast_CBE 64.4133% -97 - C1 -1WVY DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
125 HHSearch 64.0734%-102 - C1 -4GV1 AKT1_HUMAN A:[10-278] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEYL--K-----LLGKGTFGKVILVKEKATGRYYAMKILKK--EVI---VAKDEVA----H----TLTENRVLQNSRHPFLTALKYSFQTHDRLCFVME-YA-N-GGELF--FHLS--RERVF-SEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDG----HIKITDFGLC-KEGIKDGAT-MKTFCGTPEYLAPEVL-ED---NDYGRAVDWWGLGVVMYEMMCGRLPF--Y--NQD-H--E---K--LFELILM-------------------EEIR---FP------------RTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAG-----IV-WQ-----HVYE-----------------------------------------------
30 PsiBlast_CBE 63.5236%-102 - C1 -2WEL KCC2D_HUMAN A:[6-264] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQLF--E-----ELGKGAFSVVRRCMKIPTGQEYAAKIINT--KKL---SA-RDHQ----K----LEREARICRLLKHPNIVRLHDSISEEGFHYLVFD-LVTG-G-ELF--EDIVARE--YY-SEADASHCIQQILESVNHCHLN-GIVHRDLKPENLLLASKS-KGAAVKLADFGLAIEV-QGDQQA-WFGFAGTPGYLSPEVL-RK---DPYGKPVDMWACGVILYILLVGYPPFW-D--E---D--Q---HR-LYQQIKA-------------------GAYD---FP----SPE----WDTVTPEAKDLINKMLTINPAKRIT-----ASEALKHPWI--------------------------------------------------------------------
7 PsiBlast_PDB 63.3139%-106 - C1 -2YCS CHK2_HUMAN A:[16-280] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGS---GEVKLAFERKTCKKVAIKIISK--------------------N---VETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-L--TSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
9 PsiBlast_PDB 63.0839%-106 - C1 -2CN5 CHK2_HUMAN A:[22-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGSGACGEVKLAFERKTCKKVAIKIISK--R-----------------N---VETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-LGETSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
2 PsiBlast_PDB 63.0539%-107 - C1 -2YCR CHK2_HUMAN A:[16-280] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGS---GEVKLAFERKTCKKVAIKIISK--------------------N---VETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-LGETSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
58 PsiBlast_CBE 62.9834%-108 - C1 -3BHH KCC2B_HUMAN B:[6-264] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQLYED-------IGK---SVVRRCVKLCTGHEYAAKIINT--KKL---SA-RDHQ----K----LEREARICRLLKHSNIVRLHDSISEEGFHYLVFD-LVTG-G-ELF--EDIVARE--YY-SEADASHCIQQILEAVLHCHQM-GVVHRDLKPENLLLASKC-KGAAVKLADFGLAIEV-QGDQQA-WFGFAGTPGYLSPEVL-RK---EAYGKPVDIWACGVILYILLVGYPPFW-D--E---D--QH--K--LYQQIKA-------------------GAYD---FP----SPE----WDTVTPEAKNLINQMLTINPAKRIT-----AHEALKHPWV--------------------------------------------------------------------
39 PsiBlast_CBE 62.9635%-104 - C1 -2V7O KCC2G_HUMAN A:[33-291] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQLF--E-----ELGKG-FSVVRRCVKKTPTQEYAAKIINT--KKL---SA-RDHQ----K----LEREARICRLLKHPNIVRLHDSISEEGFHYLVFD-LVTG-G-ELF--EDIVARE--YY-SEADASHCIHQILESVNHIHQH-DIVHRDLKPENLLLASKC-KGAAVKLADFGLAIEV-QGEQQA-WFGFAGTPGYLSPEVL-RK---DPYGKPVDIWACGVILYILLVGYPPFW-D--E---D--QH--K--LYQQIKA-------------------GAYD---FP----SPE----WDTVTPEAKNLINQMLTINPAKRIT-----ADQALKHPWV--------------------------------------------------------------------
23 PsiBlast_CBE 62.8234%-116 - C1 -4FG8 KCC1A_HUMAN B:[14-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIRDIYD-FRD------VLGTGAFSEVILAEDKRTQKLVAIKCIAK--------------------------NEIAVLHKIKHPNIVALDDIYESGGHLYLIMQ-LV-S-GGELF--DRIV--EKGFY-TERDASRLIFQVLDAVKYLHDL-GIVHRDLKPENLLYYSLD-EDSKIMISDFG---------GSV-LSTACGTPGYVAPEVL-AQ---KPYSKAVDCWSIGVIAYILLCGYPPF--Y--D---E--N---DAKLFEQILK-------------------AEYE---FD----SPY----WDDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI--------------------------------------------------------------------
59 PsiBlast_CBE 62.6734%-106 - C1 -3BHH KCC2B_HUMAN A:[6-264] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQLYED-------IG----SVVRRCVKLCTGHEYAAKIINT--KKL---SA-RDHQ----K----LEREARICRLLKHSNIVRLHDSISEEGFHYLVFD-LVTG-G-ELF--EDIVARE--YY-SEADASHCIQQILEAVLHCHQM-GVVHRDLKPENLLLASKC-KGAAVKLADFGLAIEV-QGDQQA-WFGFAGTPGYLSPEVL-RK---EAYGKPVDIWACGVILYILLVGYPPFW-D--E---D--QH--K--LYQQIKA-------------------GAYD---FP----SPE----WDTVTPEAKNLINQMLTINPAKRIT-----AHEALKHPWV--------------------------------------------------------------------
77 PsiBlast_CBE 62.6333% -97 - C1 -3EHA DAPK1_HUMAN A:[5-275] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEK-SLT-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
74 PsiBlast_CBE 62.5833% -92 - C1 -3F5U DAPK1_HUMAN A:[6-276] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDFLAEKESLT-EEEATEF--KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
38 PsiBlast_CBE 62.4837%-107 - C1 -3HZT ? A:[12-263] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGSGAYGEVLLCKDKLTGAERAIKIIKK--SSV---TT-TSNSG---A----LLDEVAVLKQLDHPNIMKLYEFFEDKRNYYLVME-VY-R-G-GELFDEIIL---RQKF-SEVDAAVIMKQVLSGTTYLHKH-NIVHRDLKPENLLLESKS-RDALIKIVDFGLS-AH-FEVG---------TAYYIAPEVL-RK---K-YDEKCDVWSCGVILYILLCGYPPFGGQ--T---D--Q---E--ILKRVEK-------------------GKFS---FD----PPD----WTQVSDEAKQLVKLMLTYEPSKRIS-----AEEALNHPWI--------------------------------------------------------------------
29 PsiBlast_CBE 62.3835% -95 - C1 -3IGO ? A:[29-285] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGKGSFGEVLKCKDRITQQEYAVKVINK--ASA---KN-K-TS----T----ILREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYT-G-G-ELF--DEII--KRKRF-SEHDAARIIKQVFSGITYMHKH-NIVHRDLKPENILLESKE-KDCDIKIIDFGLS-TC-FQQNT--------TAYYIAPEVL-RG---T-YDEKCDVWSAGVILYILLSGTPPFYGK--N---E--Y---D--ILKRVET-------------------GKYA---FD----LPQ----WRTISDDAKDLIRKMLTFHPSLRIT-----ATQCLEHPWIQK-----YSS----------------------------------------------------------
42 PsiBlast_CBE 62.3635%-103 - C1 -2YAA DAPK2_MOUSE B:[18-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-----ELGSGQFAIVKKCREKSTGLEYAAKFIKK--RQS---RA-SRRGVCREE----IEREVSILRQVLHPNIITLHDVYENRTDVVLILE-LV-S-G-GEL--FDFLAQKESLS-EEEATSF-IKQILDGVNYLHTK-KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLA-HE-IEDGVE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANITA-------------------VSYD---FD----EEF----FSQTSELAKDFIRKLLVKETRKRLT-----IQEALRHPWI--------------------------------------------------------------------
43 PsiBlast_CBE 62.2135%-102 - C1 -2YAA DAPK2_MOUSE A:[18-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-----ELGSGQFAIVKKCREKSTGLEYAAKFIKK--RQS---RA-SRRGVCREE----IEREVSILRQVLHPNIITLHDVYENRTDVVLILE-LV-S-G-GEL--FDFLAQKESLS-EEEATSF-IKQILDGVNYLHTK-KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLA-HE-IEDGVE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANITA-------------------VSYD---FD----EEF----FSQTSELAKDFIRKLLVKETRKRLT-----IQEALRHPWI--------------------------------------------------------------------
25 PsiBlast_CBE 62.1434%-119 - C1 -4FG9 KCC1A_HUMAN A:[10-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKQAEDIRDIYD-FRD------VLGTGAFSEVILAEDKRTQKLVAIKCIAK--E----------------------ENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQ-LV-S-GGELF--DRIV--EKGFY-TERDASRLIFQVLDAVKYLHDL-GIVHRDLKPENLLYYSLD-EDSKIMISDF---------------------PGYVAPEVL-AQ---KPYSKAVDCWSIGVIAYILLCGYPPF--Y--D---E--N---DAKLFEQILK-------------------AEYE---FD----SPY----WDDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI--------------------------------------------------------------------
12 PsiBlast_PDB 62.1339%-110 - C1 -4BDG ? A:[22-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGS---GEVKLAFERKTCKKVAIKIISK--------------------N---VETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-LGETSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
70 PsiBlast_CBE 61.5135% -99 - C1 -3I7B ? A:[23-288] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQ---KT-DKES----L----LR-EVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYT-G-G-ELF--DEIIS--RKRF-SEVDAARIIRQVLSGITYMHKN-KIVHRDLKPENLLLESKS-KDANIRIIDFGLS-TH-FEASKK-MKDKIGTAYYIAPEVL-HG---T-YDEKCDVWSTGVILYILLSGCPPF--NGAN---E--Y---D--ILKKVEK-------------------GKYT---FE----LPQ----WKKVSESAKDLIRKMLTYVPSMRIS-----ARDALDHEWIQT-----Y------------------------------------------------------------
105 PsiBlast_CBE 61.0734%-101 - C1 -2CKE DAPK2_HUMAN D:[18-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-----ELGSGQFAIVKKCREKSTGLEYAAKFIKK--RQS---RA-SRRGVSREE----IEREVSILRQVLHHNVITLHDVYENRTDVVLILE-LV-S-G-GEL--FDFLAQKESLS-EEEATSF-IKQILDGVNYLHTK-KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLA-HE-IEDGVE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANITS-------------------VSYD---FD----EEF----FSHTSELAKDFIRKLLVKETRKRLT-----IQEALRHPWI--------------------------------------------------------------------
83 PsiBlast_CBE 60.8533% -97 - C1 -1P4F DAPK1_HUMAN A:[5-275] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENVD--DYYD--TGE-----ELGSGQFAVVKKCREKSTGLQYAAKFIKK--RRT---KS-SRRGVSRED----IEREVSILKEIQHPNVITLHEVYENKTDVILILE-LV-A-G-GEL--FDF-------T-EEEATEFL-KQILNGVYYLHSL-QIAHFDLKPENIMLLDRNVP--RIKIIDFGLA-HK-IDFGNE-FKNIFGTPEFVAPEIV-NY---EPLGLEADMWSIGVITYILLSGASPF--L--G---DTKQ---E--TLANVSA-------------------VNYE---FE----DEY----FSNTSALAKDFIRRLLVKDPKKRMT-----IQDSLQHPWIK-------------------------------------------------------------------
11 PsiBlast_PDB 60.8039% -99 - C1 -4A9T CHK2_HUMAN A:[22-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGS---GEVKLAFERKTCKKVAIKIISK--------------------PALNVETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-LGETSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
17 PsiBlast_PDB 60.7337%-105 - C1 -2W4O KCC4_HUMAN A:[61-309] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGRGATSIVYRCKQKGTQKPYALKVLKK----------------------------IGVLLRLSHPNIIKLKEIFETPTEISLVLE-LVTG-G-ELF--DRIV--EKGYY-SERDAADAVKQILEAVAYLHEN-GIVHRDLKPENLLYATPA-PDAPLKIADF-------------------GTPGYCAPEIL-RG---CAYGPEVDMWSVGIITYILLCGFEPF--Y--DERGD--Q---F--MFRRILN-------------------CEYY---FI----SPW----WDEVSLNAKDLVRKLIVLDPKKRLT-----TFQALQHPWV--------------------------------------------------------------------
69 PsiBlast_CBE 60.6935% -96 - C1 -3N51 ? A:[23-288] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQ---KT-DKES----L----LR-EVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYT-G-G-ELF--DEIIS--RKRF-SEVDAARIIRQVLSGITYMHKN-KIVHRDLKPENLLLESKS-KDANIRIIDFGLS-TH-FEASKK-MKDKIGTAYYIAPEVL-HG---T-YDEKCDVWSTGVILYILLSGCPPF--NGAN---E--Y---D--ILKKVEK-------------------GKYT---FE----LPQ----WKKVSESAKDLIRKMLTYVPSMRIS-----ARDALDHEWIQT-----Y------------------------------------------------------------
10 PsiBlast_PDB 60.5039%-104 - C1 -2XM9 CHK2_HUMAN A:[22-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-----TLGS---GEVKLAFERKTCKKVAIKIISK--------------------PALNVETEIEILKKLNHPCIIKIKNFFDA-EDYYIVLE-LM-E-GGELF--DKVVGNK--RL-KEATCKLYFYQMLLAVQYLHEN-GIIHRDLKPENVLLSSQE-EDCLIKITDFGHS-KI-LGETSL-MRTLCGTPTYLAPEVL-VSVGTAGYNRAVDCWSLGVILFICLSGYPPF--S--E---H--RTQVS--LKDQITS-------------------GKYN---FI----PEV----WAEVSEKALDLVKKLLVVDPKARFT-----TEEALRHPWLQD------------------------------------------------------------------
37 PsiBlast_CBE 60.4336%-105 - C1 -2VN9 KCC2D_HUMAN A:[6-264] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQLF--E-----ELGKGAFSVVRRCMKIPTGQEYAAKIINT--KKL---SA-RDHQ----K----LEREARICRLLKHPNIVRLHDSISEEGFHYLVFD-LVTG-G-ELF--EDIVARE--YY-SEADASHCIQQILESVNHCHLN-GIVHRDLKPENLLLASKS-KGAAVKLADFGLAIEV-QGDQQA-WFGFAGTPGYLSPEVL-RK---DPYGKPVDMWACGVILYILLVGYPPFW-D--E---D--Q---HR-LYQQIKA-------------------GAYD---FP----SPE----WDTVTPEAKDLINKMLTINPAKRIT-----ASEALKHPWI--------------------------------------------------------------------
16 PsiBlast_PDB 59.9037%-105 - C1 -2JAM KCC1G_HUMAN A:[15-265] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-----VLGSGAFSEVFLVKQRLTGKLFALKCIKK--S----------------S----LENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQ-LV-S-GGELF--DRIL--ERGVY-TEKDASLVIQQVLSAVKYLHEN-GIVHRDLKPENLLYLTPE-ENSKIMITDFGLS-KM--EQNGI-MSTACGTPGYVAPEVL-AQ---KPYSKAVDCWSIGVITYILLCGYPPF--Y--E---E--T---ESKLFEKIKE-------------------GYYE---FE----SPF----WDDISESAKDFICHLLEKDPNERYT-----CEKALSHPWI--------------------------------------------------------------------
106 PsiBlast_CBE 59.8034% -99 - C1 -