@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : KS6B1_HUMAN: (2013-07-22 )
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

Atome Classification :

(50 SA) .........10........20........30........40........50........60........70........80....---....90........100.......110.......120.......130....-...140.....-..-150........160.......170.......180....-...--190.......200.......210........220.......230.......240-.......250..-......260...--.-----...----270---.......280.......290....----...300......--.--310..--.---..---..320.......330......-.340.-......350.......360.......370..----.....380--.......---390.......400----...-.....410.......--420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520...
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEK---IRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKD-TAHTKAERNIL-EE-V-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-EGI--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLCKE-SIHDGTVT-HTF-CGTIEYMAPEIL--M-----RSG----HNR---AVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKC--K--LNLPP--Y---LT---QEARDLLKKLLKRNAASRLGA-GPGDA-GEVQAHPFFRHINWEELLARKVEPPFKPLLQ----SEEDVSQF--DSKFTRQ---TPVDSPDDSTLS-----ESA-NQVFLGFTYVAPSVL--ESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
78 HHSearch 83.92100%-120 * C1 *3A62 KS6B1_HUMAN A:[13-300] ------------------------------------------------------------------------------------K---IRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLK---------------KAERNIL-EE-V-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-EGI--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLC------------HTF-CGTIEYMAPEIL--M-----RSG----HNR---AVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKC--K--LNLPP--Y---LT---QEARDLLKKLLKRNAASRLGA-GPGDA-GEVQAHPFFRHINWEELLARKVEPPFKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 82.21100%-120 - C1 -3A61 KS6B1_HUMAN A:[15-299] -----------------------------------------------------------------------------------------RPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLK----------------AERNIL-EE-V-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-EGI--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFG-------------------GTIEYMAPEIL--M-----RSG----HNR---AVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKC--K--LNLPP--Y---LT---QEARDLLKKLLKRNAASRLGA-GPGDA-GEVQAHPFFRHINWEELLARKVEPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 79.47100%-119 - C1 -3A60 KS6B1_HUMAN A:[13-299] ------------------------------------------------------------------------------------K---IRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAM------------KAERNIL-EE-V-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-EGI--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLCKE----------------TIEYMAPEIL--M-----RSG----HNR---AVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKC--K--LNLPP--Y---LT---QEARDLLKKLLKRNAASRLGA-GPGDA-GEVQAHPFFRHINWEELLARKVEPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 75.63100%-112 - C1 -3A60 KS6B1_HUMAN B:[13-300] ------------------------------------------------------------------------------------K---IRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKK---------------------------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-EGI--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLCKE-S------------CGTIEYMAPEIL--M-----RSG----HNR---AVDWWSLGALMYDMLTGAPPFTGE----NRKKTIDKILKC--K--LNLPP--Y---LT---QEARDLLKKLLKRNAASRLGA-GPGDA-GEVQAHPFFRHINWEELLARKVEPPFKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 74.5545%-103 - C1 -2JDR AKT2_HUMAN A:[6-340] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII--AKDEVAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQSIT---------------------QEMFEDFDYIA----------------------------------------------------------------------------------------------------------------
68 HHSearch 74.3047%-100 - C1 -4GV1 AKT1_HUMAN A:[3-337] -----------------------------------------------------------------------------------SR---VTMNEFEYLKLLGKGTFGKVILVK---EKATGRYYAMKILKKEVIVA-KDE-VAHTLTENRVL-QN-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-ERV--FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE-GIKDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILME--E--IRFPR--T---LG---PEAKSLLSGLLKKDPKQRLGG-GSEDA-KEIMQHRFFAGIVWQHVYEKKLSPPFKPQVT----SETDTRYF--DEEFTAQ---MITITP-----SMECVDSER-RPHFPQFDYSAS---------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 74.2845%-106 - C1 -2JDO AKT2_HUMAN A:[6-340] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII--AKDEVAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQSIT-----------------------MFEDFDYIA----------------------------------------------------------------------------------------------------------------
75 HHSearch 73.7146%-102 - C1 -1O6L AKT2_HUMAN A:[1-336] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII-AKDE-VAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQ---SIT------------------QEMFEDFDYIAD---------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 73.2545%-104 - C1 -2XH5 AKT2_HUMAN A:[6-340] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII--AKDEVAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQSIT---------------------QEMFEDFDYIA----------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 72.3545%-104 - C1 -2X39 AKT2_HUMAN A:[6-340] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII--AKDEVAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQSIT---------------------QEMFEDFDYIA----------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 72.1345%-103 - C1 -2UW9 AKT2_HUMAN A:[6-340] ------------------------------------------------------------------------------------K---VTMNDFDYLKLLGKGTFGKVILVRE---KATGRYYAMKILRKEVII--AKDEVAHTVTESRVL-QN-T-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-ERV--FTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKE-GISDGATM-KTF-CGTPEYLAPEVL--E-----DND----YGR---AVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILME--E--IRFPR--T---LS---PEAKSLLAGLLKKDPKQRLGG-GPSDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVT----SEVDTRYF--DDEFTAQSIT---------------------QEMFEDFDYIA----------------------------------------------------------------------------------------------------------------
85 HHSearch 69.6937% -95 - C1 -1RDQ KAPCA_MOUSE E:[34-350] ---------------------------------------------------------------------------------SQNT---AQLDQFDRIKTLGTGSFGRVMLVK---HKESGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEALAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D-DYEEE---EIRVSINEK----------C-GKEFTEF--------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 67.4734%-110 - C1 -3QFV MRCKB_HUMAN A:[70-409] ------------------------------------------------------------------------------------Q---LHREDFEIIKVIGRGAFGEVAVVKM---KNTERIYAMKILNKWEMLKRA-E-TACFREERDVL-VN-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDK--LPEDMARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLK-MNDDGTVQ-SSVAVGTPDYISPEILQAM-----EDG----MGKYGPECDWWSLGVCMYEMLYGETPFYAE----SLVETYGKIMNHEER--FQFPS--H---VTDVSEEAKDLIQRLI---CSRERRL-GQNGI-EDFKKHAFFEGLNWENI--RNLEAPYIPDVS----SPSDTSNFDV---------------------------SGL-HLPFIGFTFTTESCF------------------------------------------------------------------------------------------------------------
81 HHSearch 67.3637%-101 - C1 -4AW2 MRCKA_RAT A:[69-412] -----------------------------------------------------------------------------------MR---LHREDFEILKVIGRGAFGEVAVVKL---KNADKVFAMKILNKWEMLK-RAE-TACFREERDVL-VN-G-DSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDR--LPEEMARFYLAEMVIAIDSVHQ-LHYVHRDIKPDNILMDMNGHIRLADFGSCLK-LMEDGTVQSSVA-VGTPDYISPEIL--QAMEGGKGR----YGP---ECDWWSLGVCMYEMLYGETPFYAE----SLVETYGKIMNHKER--FQFPT--QVTDVS---ENAKDLIRRLICSR-EHRLGQ---NGI-EDFKKHPFFSGIDWDNI--RNCEAPYIPEVS----SPTDTSNF--DVD------------------------SGH-HLPFVGFTYTSSCVL--SDR-------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 66.9935%-107 - C1 -3TKU MRCKB_HUMAN B:[86-425] ------------------------------------------------------------------------------------Q---LHREDFEIIKVIGRGAFGEVAVVKM---KNTERIYAMKILNKWEMLKRA-E-TACFREERDVL-VN-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDK--LPEDMARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLK-MNDDGTVQ-SSVAVGTPDYISPEILQAM-----EDG----MGKYGPECDWWSLGVCMYEMLYGETPFYAE----SLVETYGKIMNHEER--FQFPS--H---VTDVSEEAKDLIQRLIC-SRERRLGQ-NGIE---DFKKHAFFEGLNWENI--RNLEAPYIPDVS----SPSDTSNFD----------------------F-----SGL-HLPFIGFTFTTESCF------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 66.4155%-109 - C1 -3G51 KS6A3_MOUSE A:[14-304] ------------------------------------------------------------------------------VKEGHEK---ADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVRD----------IL-VE-V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE-SI-------------TVEYMAPEVV--N-----RRG----HTQ---SADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKA--K--LGMPQ--F---LS---PEAQSLLRMLFKRNPANRLGA-GPDGV-EEIKRHSFFSTIDWNKLYRREIHPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 65.0535%-105 - C1 -3TKU MRCKB_HUMAN A:[86-425] ------------------------------------------------------------------------------------Q---LHREDFEIIKVIGRGAFGEVAVVKM---KNTERIYAMKILNKWEMLKRA-E-TACFREERDVL-VN-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDK--LPEDMARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLK-MNDDGTVQ-SSVAVGTPDYISPEILQAM-----EDG----MGKYGPECDWWSLGVCMYEMLYGETPFYAE----SLVETYGKIMNHEER--FQFPS--H---VTDVSEEAKDLIQRLIC-SRERRLGQ-NGIE---DFKKHAFFEGLNWENI--RNLEAPYIPDVS----SPSDTSNFDV---------------------------SGL-HLPFIGFTFTTESCF------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 64.8439%-101 - C1 -2OJF KAPCA_BOVIN E:[44-329] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 63.9539% -97 - C1 -2F7E KAPCA_BOVIN E:[44-329] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 63.9554%-113 - C1 -2Z7R KS6A1_HUMAN A:[21-308] ---------------------------------------------------------------------------------GSEK---ADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL--KV------------IL-AD-V-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE---------------GTVEYMAPEVV--N-----RQG----HSH---SADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKA--K--LGMPQ--F---LS---TEAQSLLRALFKRNPANRLGS-GPDGA-EEIKRHVFYSTIDWNKLYRREIKPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 63.8839%-100 - C1 -2UZW KAPCA_BOVIN E:[29-314] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 63.8639%-102 - C1 -2OH0 KAPCA_BOVIN E:[44-329] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 63.5739%-102 - C1 -2UZT KAPCA_BOVIN A:[29-314] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 63.5154%-114 - C1 -2Z7S KS6A1_HUMAN A:[24-308] ------------------------------------------------------------------------------------K---ADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLK--------------------IL-AD-V-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE---------------GTVEYMAPEVV--N-----RQG----HSH---SADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKA--K--LGMPQ--F---LS---TEAQSLLRALFKRNPANRLGS-GPDGA-EEIKRHVFYSTIDWNKLYRREIKPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 63.5039% -99 - C1 -2F7X KAPCA_BOVIN E:[44-329] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
72 HHSearch 63.2443% -93 - C1 -3TXO KPCL_HUMAN A:[23-349] -------------------------------------------------------------------------------------------DNFEFIRVLGKGSFGKVMLARV---KETGDLYAVKVLKKDVILQ-DDD-VECTMTEKRIL-SL-ARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQK-SRR--FDEARARFYAAEIISALMFLHD-KGIIYRDLKLDNVLLDHEGHCKLADFGMCKE-GIC-----------GTPDYIAPEIL--Q-----EML----YGP---AVDWWAMGVLLYEMLCGHAPFEAE----NEDDLFEAILND--E--VVYPT--W---LH---EDATGILKSFMTKNPTMRLGSLTQGGE-HAILRHPFFKEIDWAQLNHRQIEPPFRPRIK----SREDVSNF--DPDFIKE---EPVLTPIDEGHL-----PMINQDEFRNFEYVSP---------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 62.8134%-107 - C1 -3QFV MRCKB_HUMAN B:[70-409] ------------------------------------------------------------------------------------Q---LHREDFEIIKVIGRGAFGEVAVVKM---KNTERIYAMKILNKWEMLKRA-E-TACFREERDVL-VN-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDK--LPEDMARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLK-MNDDGTVQ-SSVAVGTPDYISPEILQAM-----EDG----MGKYGPECDWWSLGVCMYEMLYGETPFYAE----SLVETYGKIMNHEER--FQFPS--H---VTDVSEEAKDLIQRLI---CSRERRL-GQNGI-EDFKKHAFFEGLNWENI--RNLEAPYIPDVS----SPSDTSNFD---------------------GF-----SGL-HLPFIGFTFTTESCF------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 62.6933% -94 - C1 -2ESM ROCK1_HUMAN A:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
84 HHSearch 62.2436%-100 - C1 -2ACX GRK6_HUMAN A:[179-518] -----------------------------------------------------------------------------------QP---VTKNTFRQYRVLGKGGFGEVCACQV---RATGKMYACKKLEKKRIKK-RKG-EAMALNEKQIL-EK-V-NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYH-MGQAGFPEARAVFYAAEICCGLEDLHR-ERIVYRDLKPENILLDDHGHIRISDLGLAVH-VP-EGQTI-KGR-VGTVGYMAPEVV--K-----NER----YTF---SPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEV--P--EEYSE--R---FS---PQARSLCSQLLCKDPAERLGC-RGGSA-REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYC-------------------------------E-----PTD-QDFYQKFATGSVPIPWQNEMVET----------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 62.0839%-101 - C1 -2UZU KAPCA_BOVIN E:[29-314] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 62.0839%-105 - C1 -2F7Z KAPCA_BOVIN E:[44-329] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKNGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 61.7733% -96 - C1 -2ETK ROCK1_HUMAN B:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
74 HHSearch 61.3847%-118 - C1 -2R5T SGK1_HUMAN A:[32-320] ----------------------------------------------------------------------------------NPH---AKPSDFHFLKVIGKGSFGKVLLARH---KAEEVFYAVKVLQKKAIL---------------VL-LKNV-KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR-ERC--FLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLDSQGHIVLTDFGLCKE-NIEHNSTT-STF-CGTPEYLAPEVL--H-----KQP----YDR---TVDWWCLGAVLYEMLYGLPPFYSR----NTAEMYDNILNK--P--LQLKP--N---IT---NSARHLLEGLLQKDRTKRLGA-K-DDF-MEIKSHVFFSLINWDDLINKKITPPFNPNVS----G-------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 61.3254%-114 - C1 -2Z7Q KS6A1_HUMAN A:[24-308] ------------------------------------------------------------------------------------K---ADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVL---------------------IL-AD-V-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE---------------GTVEYMAPEVV--N-----RQG----HSH---SADWWSYGVLMFEMLTGSLPFQGK----DRKETMTLILKA--K--LGMPQ--F---LS---TEAQSLLRALFKRNPANRLGS-GPDGA-EEIKRHVFYSTIDWNKLYRREIKPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 61.2033% -93 - C1 -2ETR ROCK1_HUMAN B:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 61.1333% -98 - C1 -2ETK ROCK1_HUMAN A:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
77 HHSearch 60.8741%-103 - C1 -1XJD A:[16-335] ------------------------------------------------------------------------------------------IEDFILHKMLGKGSFGKVFLAEF---KKTNQFFAIKALKKDVVLM-DDD-VECTMVEKRVL-SL-AWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-CHK--FDLSRATFYAAEIILGLQFLHS-KGIVYRDLKLDNILLDKDGHIKIADFGMCKE-NMLGDAKT-NTF-CGTPDYIAPEIL--L-----GQK----YNH---SVDWWSFGVLLYEMLIGQSPFHGQ----DEEELFHSIRMD--N--PFYPR--W---LE---KEAKDLLVKLFVREPEKRLGV-R-----GDIRQHPLFREINWEELERKEIDP----------------------------------------------------QNMFRNFSF------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 60.5633% -94 - C1 -2ESM ROCK1_HUMAN B:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 60.5056%-108 - C1 -4EL9 KS6A3_MOUSE A:[15-305] ------------------------------------------------------------------------------VKEGHEK---ADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVRD-RVR-----DIL-VE-V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE-S---EKKA-YSF-CGTVEYMAPEVV--N-----RRG----HTQ---SADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKA--K--LGMPQ--F---LS---PEAQSLLRMLFKRNPANRLGA-GPDGV-EEIKRHSFFSTIDWNKLYRREIHPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 60.1133% -92 - C1 -3D9V ROCK1_HUMAN B:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 60.0733% -95 - C1 -2ETR ROCK1_HUMAN A:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 59.9433% -95 - C1 -3D9V ROCK1_HUMAN A:[70-401] ------------------------------------------------------------------------------------R---MKAEDYEVVKVIGRGAFGEVQLVR---HKSTRKVYAMKLLSKFEMIKRS-D-SAFFWEERDIM-AF-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN-YD---VPEKWARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMK-MNKEGMVRCDTA-VGTPDYISPEVL--K-----SQGGDGYYGR---ECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNH--KNSLTFPDDND---IS---KEAKNLICAFLT-DREVRLGR-N--GV-EEIKRHLFFKNDQWAWETLRDTVAPVVPDLS----SDIDTSNF--DDLEEDK---GEEETFPIPKAF-----VGN-QLPFVGFTYYS----------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 59.7956%-107 - C1 -4GUE KS6A3_MOUSE A:[15-305] ------------------------------------------------------------------------------VKEGHEK---ADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVRD-RV--------L-VE-V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE------KKA-YSF-CGTVEYMAPEVV--N-----RRG----HTQ---SADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKA--K--LGMPQ--F---LS---PEAQSLLRMLFKRNPANRLGA-GPDGV-EEIKRHSFFSTIDWNKLYRREIHPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70 HHSearch 59.0955%-107 - C1 -3UBD KS6A3_MOUSE A:[7-304] ----------------------------------------------------------------------EIAITH-HVKEGHEK---ADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVRD-RV------DIL-VE-V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-EVM--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE------KKA-YSF-CGTVEYMAPEVV--N-----RRG----HTQ---SADWWSFGVLMFEMLTGTLPFQGK----DRKETMTMILKA--K--LGMPQ--F---LS---PEAQSLLRMLFKRNPANRLGA-GPDGV-EEIKRHSFFSTIDWNKLYRREIHPPFKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 58.6039% -97 - C1 -2UZV KAPCA_BOVIN A:[29-314] ---------------------------------------------------------------------------------------------FERIKTLGTGSFGRVMLVKHM---ETGNHYAMKILDKQKVVK-LKQ-IEHTLNEKRIL-QA-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-IGR--FSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-V---KGRT-WTL-CGTPEYLAPEII--L-----SKG----YNK---AVDWWALGVLIYEMAAGYPPFFAD----QPIQIYEKIVSG--K--VRFPS--H---FS---SDLKDLLRNLLQVDLTKRFGN-LKDGV-NDIKNHKWFATTDWIAIYQRKVEAPFIPKFK----GPGDTSNF--D---------------------------------------------------------------------------------------------------------------------------------------------------------